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| 1 | FibroSURE^(TM) and FibroScan~ in relation to treatment response in chronic hepatitis C virus显示文摘AIM:To compare histological endpoint assessment using noninvasive alternatives to biopsy during treatment in a chronic hepatitis C virus(HCV)cohort.METHODS:Patients with chronic HCV were randomized to receive interferon-based therapy for 24(genotypes 2/3)or 48(genotype 1)wk.FibroSURE~TM(FS)was assessed at baseline and at week-12 post-treatment follow-up.Baseline biopsy for METAVIR was assessed by a single pathologist.FibroScan~ transient elastogra-phy(TE)was performed during treatment in a patient subset.RESULTS:Two thousand and sixty patients(n = 253 in Asia)were classif ied as METAVIR F0-1(n = 1682)or F2-4(n = 378).For F2-4,FS(n = 2055)had sensitiv-ity and specif icity of 0.87 and 0.61,respectively,with area under the receiver-operating curve of 0.82;corre-sponding values for TE(n = 214)and combined FS/TE(n = 209)were 0.77,0.88 and 0.88,and 0.93,0.68 and 0.88.Overall FS/TE agreement for F2-4 was 71%(κ = 0.41)and higher in Asians vs non-Asians(κ = 0.86 vs 0.35;P < 0.001).Combined FS/TE had 97% accuracy in Asians(n = 33).Baseline FS(0.38 vs 0.51,P < 0.001)and TE(8.0 kPa vs 11.9 kPa,P = 0.006)scores were lower in patients with sustained virological response than in nonresponders,and were maintained through follow-up.CONCLUSION:FS and TE may reliably differentiate mild from moderate-advanced disease,with a potential for high diagnostic accuracy in Asians with chronic HCV. | Keyur Patel Mireen Friedrich-Rust Yoav Lurie Mircea Grigorescu Carol Stanciu Chuan-Mo Lee Eugene R Schiff Dieter Hussinger Michael P Manns Guido Gerken Isabelle Colle Michael Torbenson Erik Pulkstenis G Mani Subramanian John G McHutchison Stefan Zeuzem | 2011 | World Journal of Gastroenterology2011，17，41： | 4 |
| 2 | Hepatopulmonary syndrome and portopulmonary hypertension: recent knowledge in pathogenesis and overview of clinical assessment显示文摘 | Sarah Raevens Anja Geerts Christophe Van Steenkiste Xavier Verhelst Hans Van Vlierberghe Isabelle Colle | 2015 | Liver Int2015，，6： | 2 |
| 3 | Modulation of Portal Graft Inflow: A Necessity in Adult Living-Donor Liver Transplantation?显示文摘 | Roberto Troisi Guy Cammu Giuseppe Militerno Luc De Baerdemaeker Johan Decruyenaere Eric Hoste Peter Smeets Isabelle Colle Hans Van Vlierberghe Mirko Petrovic Dirk Voet Eric Mortier Uwe J. Hesse Bernard de Hemptinne | 2003 | Annals of Surgery2003，，3： | 2 |
| 4 | Angiogenesis in liver disease显示文摘 | Mercedes Fernández David Semela Jordi Bruix Isabelle Colle Massimo Pinzani Jaume Bosch | 2009 | Journal of Hepatology2009，，3： | 2 |
| 5 | Evaluation of inflammatory and angiogenic factors in patients with non-alcoholic fatty liver disease显示文摘 | Stephanie Coulon Sven Francque Isabelle Colle An Verrijken Bram Blomme Femke Heindryckx Steffi De Munter Janne Prawitt Sandrine Caron Bart Staels Hans Van Vlierberghe Luc Van Gaal Anja Geerts | 2012 | Cytokine2012，，： | 1 |
| 6 | Oral vasodilator therapy in patients with moderate to severe portopulmonary hypertension as a bridge to liver transplantation显示文摘 | Sarah Raevens Michel De Pauw Koen Reyntjens Anja Geerts Xavier Verhelst Frederik Berrevoet Xavier Rogiers Roberto I. Troisi Hans Van Vlierberghe Isabelle Colle | 2013 | European Journal of Gastroenterology & Hepatology2013，，4： | 1 |
| 7 | Arterial embolisation or chemoembolisation versus symptomatic treatment in patients with unresectable hepatocellular carcinoma: a randomised controlled trial显示文摘 | Josep M Llovet Maria Isabel Real Xavier Monta?a Ramon Planas Susana Coll John Aponte Carmen Ayuso Margarita Sala Jordi Muchart Ricard Solà Joan Rodés Jordi Bruix | 2002 | The Lancet2002，，9319： | 1 |
| 8 | Diagnosis of portopulmonary hypertension in candidates for liver transplantation: A prospective study显示文摘 | Isabelle O. Colle Richard Moreau Erica Godinho Jacques Belghiti Florence Ettori Alain Cohen-Solal Hervé Mal Jacques Bernuau Jean Marty Didier Lebrec Dominique Valla Fran?ois Durand | 2003 | Hepatology2003，，2： | 1 |
| 9 | Arterial embolisation or chemoembolisation versus symptomatic treatment in patients with unresectable hepatocellular carcinoma: a randomised controlled trial显示文摘 | Josep M Llovet Maria Isabel Real Xavier Monta?a Ramon Planas Susana Coll John Aponte Carmen Ayuso Margarita Sala Jordi Muchart Ricard Solà Joan Rodés Jordi Bruix | 2002 | The Lancet2002，，9319： | 1 |
| 10 | Evaluation of inflammatory and angiogenic factors in patients with non-alcoholic fatty liver disease显示文摘 | Stephanie Coulon Sven Francque Isabelle Colle An Verrijken Bram Blomme Femke Heindryckx Steffi De Munter Janne Prawitt Sandrine Caron Bart Staels Hans Van Vlierberghe Luc Van Gaal Anja Geerts | 2012 | Cytokine2012，，2： | 1 |
| 11 | Detection of QTL affecting fatty acid composition in the pig显示文摘 | Alex Clop Cristina Ovilo Miguel Perez-Enciso Albert Cercos Anna Tomas Ana Fernandez Agustina Coll Josep M. Folch Carmen Barragan Isabel Diaz Maria A. Oliver Luis Varona Luis Silio Armand Sanchez Jose L. Noguera | 2003 | Mammalian Genome2003，，9： | 1 |
| 12 | Arterial embolisation or chemoembolisation versus symptomatic treatment in patients with unresectable hepatocellular carcinoma: a randomised controlled trial显示文摘 | Josep M Llovet Maria Isabel Real Xavier Monta?a Ramon Planas Susana Coll John Aponte Carmen Ayuso Margarita Sala Jordi Muchart Ricard Solà Joan Rodés Jordi Bruix | 2002 | The Lancet2002，，9319： | 1 |
| 13 | Arterial embolisation or chemoembolisation versus symptomatic treatment in patients with unresectable hepatocellular carcinoma: a randomised controlled trial显示文摘 | Josep M Llovet Maria Isabel Real Xavier Monta?a Ramon Planas Susana Coll John Aponte Carmen Ayuso Margarita Sala Jordi Muchart Ricard Solà Joan Rodés Jordi Bruix | 2002 | The Lancet2002，，9319： | 1 |
| 14 | N -glycan based biomarker distinguishing non-alcoholic steatohepatitis from steatosis independently of fibrosis显示文摘 | Bram Blomme Sven Francque Eric Trépo Louis Libbrecht Dieter Vanderschaeghe An Verrijken Piet Pattyn Yves Van Nieuwenhove Dirk Van De Putte Anja Geerts Isabelle Colle Joris Delanghe Christophe Moreno Luc Van Gaal Nico Callewaert Hans Van Vlierberghe | 2011 | Digestive and Liver Disease2011，，4： | 1 |
| 15 | Detection of QTL affecting fatty acid composition in the pig显示文摘 | Alex Clop Cristina Ovilo Miguel Perez-Enciso Albert Cercos Anna Tomas Ana Fernandez Agustina Coll Josep M. Folch Carmen Barragan Isabel Diaz Maria A. Oliver Luis Varona Luis Silio Armand Sanchez Jose L. Noguera | 2003 | Mammalian Genome2003，，9： | 1 |
| 16 | Enteral nutrition with or without N -acetylcysteine in the treatment of severe acute alcoholic hepatitis: A randomized multicenter controlled trial显示文摘 | Christophe Moreno Philippe Langlet Axel Hittelet Luc Lasser Delphine Degré Sylvie Evrard Isabelle Colle Arnaud Lemmers Jacques Devière Olivier Le Moine | 2010 | Journal of Hepatology2010，，6： | 1 |
| 17 | Arterial embolisation or chemoembolisation versus symptomatic treatment in patients with unresectable hepatocellular carcinoma: a randomised controlled trial显示文摘 | Josep M Llovet Maria Isabel Real Xavier Monta?a Ramon Planas Susana Coll John Aponte Carmen Ayuso Margarita Sala Jordi Muchart Ricard Solà Joan Rodés Jordi Bruix | 2002 | The Lancet2002，，9319： | 1 |
| 18 | Arterial embolisation or chemoembolisation versus symptomatic treatment in patients with unresectable hepatocellular carcinoma: a randomised controlled trial显示文摘 | Josep M Llovet Maria Isabel Real Xavier Monta?a Ramon Planas Susana Coll John Aponte Carmen Ayuso Margarita Sala Jordi Muchart Ricard Solà Joan Rodés Jordi Bruix | 2002 | The Lancet2002，，9319： | 1 |
| 19 | Hepatitis B virus and hepatitis C virus infections in Belgium: similarities and differences in epidemics and initial management显示文摘 | Bénédicte De Vroey Christophe Moreno Wim Laleman Marc van Gossum Isabelle Colle Chantal de Galocsy Philippe Langlet Geert Robaeys Hans Orlent Peter Michielsen Jean Delwaide Hendrik Reynaert Fran?ois D’Heygere Dirk Sprengers Stefan Bourgeois Collins Assene | 2013 | European Journal of Gastroenterology & Hepatology2013，，5： | 1 |
| 20 | Diagnosis of portopulmonary hypertension in candidates for liver transplantation: A prospective study显示文摘 | Isabelle O. Colle Richard Moreau Erica Godinho Jacques Belghiti Florence Ettori Alain Cohen-Solal Hervé Mal Jacques Bernuau Jean Marty Didier Lebrec Dominique Valla Fran?ois Durand | 2003 | Hepatology2003，，2： | 1 |
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