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时间 1989 - 2010 学科选择学科
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19篇 您的检索式：作者名="David Margolis"
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    题名 作者 年代 出处 被引量
1Yin and Yang of mesenchymal stem cells and aplastic anemia显示文摘Acquired aplastic anemia(AA) is a bone marrow failure syndrome characterized by peripheral cytopenias and bone marrow hypoplasia. It is ultimately fatal without treatment, most commonly from infection or hemorrhage. Current treatments focus on suppressing immune-mediated destruction of bone marrow stem cells or replacing hematopoietic stem cells(HSCs) by transplantation. Our incomplete understanding of the pathogenesis of AA has limited development of targeted treatment options. Mesenchymal stem cells(MSCs) play a vital role in HSC proliferation; they also modulate immune responses and maintain an environment supportive of hematopoiesis. Some of the observed clinical manifestations of AA can be explained by mesenchymal dysfunction. MSC infusions have been shown to be safe and may offer new approaches for the treatment of this disorder. Indeed, infusions of MSCs may help suppress auto-reactive, T-cell mediated HSC destruction and help restore an environment that supports hematopoiesis. Small pilot studies using MSCs as monotherapy or as adjuncts to HSC transplantation have been attempted as treatments for AA. Here we review the current understanding of the pathogenesis of AA and the function of MSCs, and suggest that MSCs should be a target for further research and clinical trials in this disorder.Larisa Broglie David Margolis Jeffrey A Medin 2017World Journal of Stem Cells2017，9，12：3
2Effectiveness of recombinant human platelet - derived growth factor for the treament of diabetic neuropathic foot ulcers 显示文摘David J Margolis M 2005Wound Repair Regener2005，13，18：1
3Prevalence of Incidental Findings on Abdominal Computed Tomography Angiograms on Prospective Renal Donors显示文摘Nelly Tan Aphinya Charoensak Khobkhoon Ajwichai Hans Albin Gritsch Gabriel Danovitch Peter Schulam David S.K. Lu Daniel J. Margolis Steven S. Raman 2015Transplantation2015，，6：1
4Extrinsic risk factors for pressure ulcer early in the hospital stay: A nested case control study显示文摘Mona Baumgarten David J Margolis 2008The Journal of Gerontology2008，63，4：1
5Enteric Neuronal Density Contributes to the Severity of Intestinal Inflammation显示文摘Kara Gross Margolis Korey Stevanovic Nima Karamooz Zi Shan Li Ankur Ahuja Fabien D’Autréaux Virginia Saurman Alcmene Chalazonitis Michael David Gershon 2011Gastroenterology2011，，2：1
6Calcium Plus Vitamin D Supplementation and the Risk of Incident Diabetes in the Women’s Health Initiative显示文摘Connelly Stephanie Curb J David Howard Barbara V Kestenbaum Bryan Larson Joseph C Manson JoAnn E Margolis Karen L Siscovick David S Weiss Noel S 2008Diabetes Care2008，，4：1
7Incidence and Prognosis of Resistant Hypertension in Hypertensive Patients显示文摘Stacie L. Daugherty J. David Powers David J. Magid Heather M. Tavel Frederick A. Masoudi Karen L. Margolis Patrick J. O?Connor Joe V. Selby P. Michael Ho 2012Circulation2012，，13：1
8Variation in Care in Pediatric Crohn Disease显示文摘Richard B Colletti Robert N Baldassano David E Milov Peter A Margolis Athos Bousvaros Wallace V Crandall Karen D Crissinger Michael A D?Amico Andrew S Day Lee A Denson Marla Dubinsky Dawn R Ebach Edward J Hoffenberg Howard A Kader David J Keljo Ian H Leib 2009Journal of Pediatric Gastroenterology and Nutrition2009，，3：1
9Immediate antiviral therapy appears to restrict resting CD4+ cell HIV-1 infection without accelerating the decay of latent infection显示文摘Nancie M. Archin Naveen K. Vaidya JoAnn D. Kuruc Abigail L. Liberty Ann Wiegand Mary F. Kearney Myron S. Cohen John M. Coffin Ronald J. Bosch Cynthia L. Gay Joseph J. Eron David M. Margolis Alan S. Perelson Proceedings of the National Academy of Sciences0，，：1
10Acute Pancreatitis with Hyperlipemia: The Incidence of Lipid Abnormalities in Acute Pancreatitis显示文摘JOHN L CAMERON DAVID M. CAPUZZI GEORGE D. ZUIDEMA SIMEON MARGOLIS 1973Annals of Surgery1973，，4：1
11Association of Crohn’s Disease, Thiopurines, and Primary Epstein-Barr Virus Infection with Hemophagocytic Lymphohistiocytosis显示文摘Vincent F. Biank Mehul K. Sheth Julie Talano David Margolis Pippa Simpson Subra Kugathasan Michael Stephens 2011The Journal of Pediatrics2011，，5：1
12Prevalence of cardiovascular risk factors in patients with psoriasis显示文摘Andrea L. Neimann Daniel B. Shin Xingmei Wang David J. Margolis Andrea B. Troxel Joel M. Gelfand 2006Journal of the American Academy of Dermatology2006，，：1
13Diabetes, lower extremity amputation, loss of protective sensation, and neuronal nitric oxide synthase associated protein in the C hronic R enal I nsufficiency C ohort study显示文摘David J. Margolis Jayanta Gupta Stephen R. Thom Raymond R. Townsend Peter A. Kanetsky Ole Hoffstad Maryte Papdopoulos Michael Fischer Jeffrey R. Schelling Nandita Mitra 2012Wound Repair Regen2012，，1：1
14'Minimum Wages and Employment in France and the United States'显示文摘 John M & Kramarz Francis & Margolis David N 1999CEPR Discussion Papers with number 21591999，1999，：1
15Diffusion Tensor Magnetic Resonance Tractography of the Prostate: Feasibility for Mapping Periprostatic Fibers显示文摘David S. Finley Benjamin M. Ellingson Shyam Natarajan Taryar M. Zaw Steve S. Raman Peter Schulam Robert E. Reiter Daniel Margolis 2012Urology2012，，：1
16Prevention of Cardiovascular Disease in Persons with Type 2 Diabetes Mellitus: Current Knowledge and Rationale for the Action to Control Cardiovascular Risk in Diabetes (ACCORD) Trial显示文摘David C. Goff Hertzel C. Gerstein Henry N. Ginsberg William C. Cushman Karen L. Margolis Robert P. Byington John B. Buse Saul Genuth Jeffrey L. Probstfield Denise G. Simons-Morton 2007The American Journal of Cardiology2007，，12：1
17Prefrontal executive function associated coupling relates to Huntington’s disease stage显示文摘Paul G. Unschuld Xinyang Liu Megan Shanahan Russell L. Margolis Susan S. Bassett Jason Brandt David J. Schretlen Graham W. Redgrave Jun Hua Christoph Hock Sarah A. Reading Peter C.M. van Zijl James J. Pekar Christopher A. Ross 2013Cortex2013，，：1
18Effectiveness of platelet releasate for the treatment of diabetic neuropathic foot ulcers显示文摘David J Margolis DJ Kantor J 2001Diabetes Care(S1475--3898)2001，24，：1
19Impaired cortico-striatal functional connectivity in prodromal Huntington’s Disease显示文摘Paul G. Unschuld Suresh E. Joel Xinyang Liu Megan Shanahan Russell L. Margolis Kevin M. Biglan Susan S. Bassett David J. Schretlen Graham W. Redgrave Peter C.M. van Zijl James J. Pekar Christopher A. Ross 2012Neuroscience Letters2012，，2：1
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