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| 1 | Effect of age on aortic atherosclerosis显示文摘Objective To examine the association of atherosclerosis burden in the survivors of an asymptomatic elderly cohort study and its relationship to other coronary risk factors (specifically, age) by evaluating aortic atherosclerotic wall burden by magnetic resonance imaging (MRI). Methods A total of 312 participants in an ongoing observational cohort study underwent cardiac and descending thoracic aorta imaging by MRI. Maximum wall thickness was measured and the mean wall thickness calculated.Wall/outer wall ratio was used as a normalized wall index (NWI) adjusted for artery size difference among participants. Percent wall volume (PWV) was calculated as NWI ×100.Results In this asymptomatic cohort (mean age: 76 years), the mean (SD) aortic wall area andwall thicknesswere 222 ±45 mm2 and 2.7 ±0.4 mm, respectively. Maximum wall thickness was 3.4 ±0.6 mm, and PWV was 32% ±4%. Women appeared to have smaller wall area,but after correcting for their smaller artery size, had significantly higher PWV than men (P = 0.03). Older age was associatedwith larger wall area (P = 0.04 for trend) with similar PWVs. However, there were no statistically significant associations between standard risk factors,Framingham global risk, or metabolic syndrome status, therapy for cholesterol or hypertension, coronary or aortic calcium score, and the aortic wall burden. Aortic calcificationwas associated with coronary calcification. Conclusions Asymptomatic elderly in this cohort had a greater descending thoracic aortic wall volume that correlated with age, andwomen had a significantly increased PWV compared to men. In these survivors, the atherosclerotic aortic wall burden was not significantly associated with traditional risk factors or with coronary or aortic calcium scores or coronary calcium progression. Results suggest that age, or as yet unidentified risk factor(s), may be responsible for the increase in atherosclerosis. | Michael A. Chen Miwa Kawakubo Patrick M. Colletti Dongxiang Xu Laurie LaBree Dustin Robert Detrano Stanley P Azen Nathan D. Wong Xue-Qiao Zhao | 2013 | Journal of Geriatric Cardiology2013，10，2： | 6 |
| 2 | Transient elastography: A non-invasive tool for assessing liver fibrosis in HIV/HCV patients显示文摘AIM: To assess the prevalence of advanced liver fibrosis (ALF) in human immunodeficiency virus (HIV), hepatitis C virus (HCV) and HIV/HCV patients using transient elastography, and to identify factors associated with ALF. METHODS: Between September 2008 and October 2009, 71 HIV mono-infected, 57 HIV/HCV co-infected and 53 HCV mono-infected patients on regular follow-up at our Center were enrolled in this study. Alcohol intake, the main parameters of liver function, presence of HCV-RNA, HIV-RNA, duration of highly active anti-retroviraltherapy (HAART) and CD4 cell count were recorded. ALF was defined as liver stiffness (LS) ≥ 9.5 kPa. To estimate liver fibrosis (LF) a further 2 reliable biochemical scores, aspartate aminotransferase platelet ratio index (APRI) and FIB-4, were also used. RESULTS: LS values of co-infected patients were higher than in either HIV or HCV mono-infected patients (χ 2M H = 4, P < 0.04). In fact, LS ≥ 9.5 was significantly higher in co-infected than in HIV and HCV mono-infected pa-tients (χ 2 = 5, P < 0.03). Also APRI and the FIB-4 index showed more LF in co-infected than in HIV mono-infect-ed patients (P < 0.0001), but not in HCV mono-infected patients. In HIV?HCV co-infected patients, the extent of LS was significantly associated with alcohol intake (P < 0.04) and lower CD4+ cell count (P < 0.02). In HCV pa-tients, LS was correlated with alcohol intake (P < 0.001) and cholesterol levels (P < 0.03). Body mass index, dia-betes, HCV-and HIV-viremia were not significantly cor-related with LS. In addition, 20% of co-infected patients had virologically unsuccessful HAART; in 50% compliance was low, CD4+ levels were < 400 cells/mm 3 and LS was > 9.5 kPa. There was no significant correlation between extent of LF and HAART exposure or duration of HAART exposure, in particular with specific dideoxynucleoside analogues. CONCLUSION: ALF was more frequent in co-infected than mono-infected patients. This result correlated with lower CD4 levels. Protective immunological effects of HAART on LF progression outweigh its hepatotoxic effects. | Valentina Li Vecchi Maurizio Soresi Claudia Colomba Giovanni Mazzola Pietro Colletti Maurizio Mineo Paola Di Carlo Emanuele La Spada Giovanni Vizzini Giuseppe Montalto | 2010 | World Journal of Gastroenterology2010，16，41： | 4 |
| 3 | Evidence-based Guidelines From ESPGHAN and NASPGHAN for Helicobacter pylori Infection in Children显示文摘 | Sibylle Koletzko Nicola L. Jones Karen J. Goodman Benjamin Gold Marion Rowland Samy Cadranel Sonny Chong Richard B. Colletti Thomas Casswall Yoram Elitsur Jeannette Guarner Nicolas Kalach Armando Madrazo Francis Megraud Giuseppina Oderda | 2011 | Journal of Pediatric Gastroenterology and Nutrition2011，，2： | 2 |
| 4 | Stem cell factor and c-kit are involved in hepatic recovery after acetaminophen-induced liver injury in mice显示文摘 | Hu B Colletti LM | 2008 | Am J Physiol Gastrointest Liver Physiol2008，295，： | 1 |
| 5 | Collagenous gastri- tis: a long-term follow-up with the development of endo- crine cell hyperplasia, intestinal metaplasia, and epithelial changes indeterminate for dysplasia 显示文摘 | Winslow JL Trainer TD Colletti RB | 2001 | Am J Clin- Pathol2001，，5： | 1 |
| 6 | Intraoperative monitoring for hearing preservation and restoration in acoustic neuroma surgery 显示文摘 | Colletti V Fiorino FG Carner M | 2000 | Skull Base Surg2000，10，4： | 1 |
| 7 | Pediatric Procedural Sedation and Anal- gesia 显示文摘 | Doyle L Colletti JE | 2006 | Pediatr Clin North Am2006，53，2： | 1 |
| 8 | The ratio of ELR_ to ELR- CXC chemokines affects the lung and liver injury following hepatic ischemia/reperfusion in the rat 显示文摘 | Colletti L M Green M E Burdick M D | 2000 | Hepatology2000，31，： | 1 |
| 9 | Mini-retromandibular approach to condylar fractures显示文摘 | Biglioli F Colletti G | 2008 | J Craniomaxillofac Surg2008，36，7： | 1 |
| 10 | IL-22 is involved in liver regeneration after hepatectomy 显示文摘 | Ren XD Hu B Colletti LM | 2010 | Am J Physiol Gastrointest Liver Physiol2010，298，1： | 1 |
| 11 | Myelin-containing corpora amylacea in vestibular root entry zone 显示文摘 | Sabarbati A Carner M Colletti V | 1995 | Ul- trastruct Path1995，20，5： | 1 |
| 12 | Stem cell factor and its receptor, c-kit,are important for hepatocyte proliferation in wild-type and tumor necrosis factor receptor-1 knockout mice after 70% hepatectomy 显示文摘 | Ren XD Hu B Colletti L | 2008 | Surgery2008，143，6： | 1 |
| 13 | Tympanometry from 200 to 2 000Hz probe tone显示文摘 | Colletti V | 1976 | Audiology1976，15，： | 1 |
| 14 | Tumor neerosisfaetor up - regulates intracellular adhesion molecule 1, which is important in the neutrophil - dependent lung and liver injury associated with hepatic ischemia and reperfusion in the rat 显示文摘 | Colletti JM Cortis A Lukacs N | 1998 | Shock1998，10，3： | 1 |
| 15 | MR findings in patients with acute tibial plateau fractures 显示文摘 | Colletti P Greenberg H Terk MR | 1996 | Comput Med Imaging Graph1996，20，3： | 1 |
| 16 | The impact on treatment planning of MRI of the spine in patients suspected of vertebral metastasis: an efficacy study显示文摘 | Colletti PM Siegel HJ Woo MY | 1996 | Comput Med Imaging Graph1996，90，3： | 1 |
| 17 | Advances in monitoring of seventh and eighth cranial nerve function during posterior fossa surgery显示文摘 | Colletti V Fiorino FG | 1998 | Am J Otol1998，19，4： | 1 |
| 18 | Transmasseter approach to condylar frac- tures by mini-retromandibular access显示文摘 | Biglioli F Colletti G | 2009 | J Oral Maxillafac Surg2009，67，11： | 1 |
| 19 | The floating mass transducer for external auditory' canal and middle ear malformations 显示文摘 | Colletti L Carner M Mandala M | 2011 | Otol Neurotol2011，32，1： | 1 |
| 20 | Tumor necrosis factor up-regulates intercellular adhesion molecule1,which is important in the neutrophil-dependent lung and liver injury associated with hepatic ischemia and reperfusion in the rat显示文摘 | COLLETTI L CORTIS A LUKACS N | 1998 | Shock1998，10，3： | 1 |
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