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93篇 您的检索式:作者名="Redgrave"
    题名 作者 年代 出处 被引量
1A simple score (ABCD) to identify individuals at high early risk of stroke after transient ischaemic attack显示文摘PM Rothwell MF Giles E Flossmann CE Lovelock JNE Redgrave CP Warlow Z Mehta 2005The Lancet2005,,9479:3
2Remote ischaemic conditioning for stroke: unanswered questions and future directions显示文摘Remote ischaemic conditioning(RIC)refers to a process whereby periods of intermittent ischaemia,typically via the cyclical application of a blood pressure cuff to a limb at above systolic pressure,confers systemic protection against ischaemia in spatially distinct vascular territories.The mechanisms underlying this have not been characterised fully but have been shown to involve neural,hormonal and systemic inflammatory signalling cascades.Preclinical and early clinical studies have been promising and suggest beneficial effects of RIC in acute ischaemic stroke,symptomatic intracranial stenosis and vascular cognitive impairment.Through systematic searches of several clinical trials databases we identified 48 active clinical trials of RIC in ischaemic stroke,intracerebral haemorrhage and subarachnoid haemorrhage.We summarise the different RIC protocols and outcome measures studied in ongoing clinical trials and highlight which studies are most likely to elucidate the underlying biological mechanisms of RIC and characterise its efficacy in the near future.We discuss the uncertainties of RIC including the optimal frequency and duration of therapy,target patient groups,cost-effectiveness,the confounding impact of medications and the absence of a clinically meaningful biomarker of the conditioning response.With several large clinical trials of RIC expected to report their outcomes within the next 2 years,this review aims to highlight the most important studies and unanswered questions that will need to be addressed before this potentially widely accessible and low-cost intervention can be used in clinical practice.Sheharyar Baig Bethany Moyle Krishnan Padmakumari Sivaraman Nair Jessica Redgrave Arshad Majid Ali Ali 2021Stroke & Vascular Neurology2021,6,2:2
3Brain metabolite alterations and cognitive dysfunction in early Huntington’s disease显示文摘Paul G. Unschuld Richard A. E. Edden Aaron Carass Xinyang Liu Megan Shanahan Xin Wang Kenichi Oishi Jason Brandt Susan S. Bassett Graham W. Redgrave Russell L. Margolis Peter C. M. van Zijl Peter B. Barker Christopher A. Ross 2012Mov Disord2012,,7:1
4A simple score (ABCD) to identify individuals at high early risk of stroke after transient ischaemic attack显示文摘PM Rothwell MF Giles E Flossmann CE Lovelock JNE Redgrave CP Warlow Z Mehta 20052005 (9479)2005,,9479:1
5Histological assessment of 526 symptomatic carotid plaques in relation to the nature and timing of ischemic symptoms:the Oxford plaque study显示文摘Redgrave JN Lovett JK Gallagher PJ 0,,19:1
6Functional properties of the basal ganglia' s re entrant loop architecture: Selection and reinforcement 显示文摘Redgrave P 2011of neuroscience2011,,7:1
7Goal-directed and habitual control in the basal ganglia: implications for Parkinson's disease显示文摘Redgrave P Rodriguez M Smith Y 2010Nature Reviews Neuroscienee2010,11,11:1
8A computational model of action selection in the basal ganglia I: A new ftmetional anatomy 显示文摘Gurney K Prescott T J Redgrave P 2001Biological Cybernetic (S0340-1200)2001,84,6:1
9Presence of acute ischaemic lesions ou diffusion-weighted imaging is associ-ated with clinical predictors of early risk of stroke after transient ischaemie attack显示文摘Redgrave JN Schulz UG Briley D 2007Cerebrovasc Dis2007,24,1:1
10Systematic review of associations between the presence of acute ischemic lesions on diffusion weighted imaging and clinical predictors of early stroke risk after tran- sient ischemic attack显示文摘Redgrave J N Coutts SB Schulz UG 2007Stroke2007,38,5:1
11A simple score (ABCD) to identify individuals at high early risk of stroke after transient ischaemic attack显示文摘PM Rothwell MF Giles E Flossmann CE Lovelock JNE Redgrave CP Warlow Z Mehta 2005The Lancet2005,,9479:1
12Histological assessment of 526 symptomaticcarotid plaques in relation to the nature and timing of ischemic symptoms:the Oxford plaquestudy显示文摘Redgrave JN Lovett JK Gallagher PJ 2006Circulation2006,113,19:1
13Histological features of carotid plaque in patients with ocular ischemia versus cerebral events显示文摘Howard DP van Lammeren GW Redgrave JN 2013Stroke2013,44,3:1
14Histological assessment of 526 symptomatic carotid plaques in relation to the nature and timing of ischemic symptoms : the Oxford Plaque Study 显示文摘Redgrave JN Lovett JK Gallagher PJ 2006Circulation2006,113,19:1
15Goal-directed and habitual control in the basal ganglia: implications for Parkinson's disease显示文摘Redgrave P Rodriguez M Smith 2010Na- ture Reviews Neuroseience2010,11,11:1
16Submicron lipid emulsion containing amphipathic polyethylene glycol for use as drug-carries with prolonged circulation time 显示文摘Lundeberg B B Mortimer B C Redgrave T G 1996Int J Pharm1996,134,12:1
17glycol for as drug-carriers with prolonged circulation time 显示文摘Lundberg B B Mortimer B C Redgrave T (2 Submicron lipid emulsion containing amphipathic polyethylene 1996lnt J Pharm1996,134,12:1
18Submicron lipid emulsions containing amphipathic polyethylene glycol for use as drugcarries with prolonged circulation time显示文摘Lundberg BB Mortimer BC Redgrave TG 1996Int J Pharm1996,134,12:1
19Presence of acute ischaemic lesions on diffusion--weighted imaging is associated with clinical predictors of early risk of stroke after transient isehaemic attack显示文摘Redgrave JN Schulz UG Briley D 2007Cerebrovasc Dis2007,24,1:1
20Systematic review of associations between the presence of acute ischemic lesions on diffusion-weighted imaging and clinical predictors of early stroke risk after transient ischemic attack显示文摘Redgrave JN Coutts SB Schulz UG 2007Stroke2007,38,:1
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