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| 1 | Key factors in developing the trinitrobenzene sulfonic acid-induced post-inflammatory irritable bowel syndrome model in rats显示文摘AIM:To investigate the key factors in developing the trinitrobenzene sulfonic acid(TNBS)-induced postinflammatory irritable bowel syndrome(PI-IBS)model in rats. METHODS:TNBS was administered to rats at the following conditions:(1)with different doses(20,10,5 mg/0.8 mL per rat);(2)with same dose in different concentrations(20 mg/rat,25,50 mg/mL);(3)in different ethanol percentage(25%,50%);and(4)at depth either 4 cm or 8 cm from anus.At 5 d and 4 wk after TNBS administration,inflammation severity and inflammation resolution were evaluated.At 4 and 8 wk after TNBS application,visceral hyperalgesia and enterochromaffin(EC)cell hyperplasia were assayed by abdominal withdrawal reflex test,silver staining and capillary electrophoresis. RESULTS:Our results showed that:(1)TNBS induced dose-dependent acute inflammation and inflammation resolution.At 5 d post TNBS,the pathological score and myeloperoxidase(MPO)activity in all TNBS treated rats were significantly elevated compared to that of the control(9.48±1.86,8.18±0.67,5.78± 0.77 vs 0,and 3.55±1.11,1.80±0.82,0.97±0.08 unit/mg vs 0.14±0.01 unit/mg,P<0.05).At 4 wk post TNBS,the pathological score in high and median dose TNBS-treated rats were still significantly higher than that of the control(1.52±0.38 and 0.80±0.35 vs 0,P<0.05);(2)Intracolonic TNBS administration position affected the persistence of visceral hyperalgesia.At 4 wk post TNBS,abdominal withdrawal reflex (AWR)threshold pressure in all TNBS-treated groups were decreased compared to that of the control(21.52 ±1.73 and 27.10±1.94 mmHg vs 34.44±1.89 mmHg,P<0.05).At 8 wk post TNBS,AWR threshold pressure in 8 cm administration group was still significantly decreased(23.33±1.33 mmHg vs 36.79±2.29 mmHg,P<0.05);(3)Ethanol percentage affected the TNBS-induced inflammation severity and visceral hyperalgesia.In TNBS-25%ethanol-treated group,the pathological score and MPO activity were significantly lowered compared to that of the TNBS-50%ethanoltreated group,while AWR threshold pressure were significantly elevated(36.33±0.61 mmHg vs 23.33±1.33 mmHg,P<0.05);and(4)TNBS(5 mg/0.8 mL per rat, in 50%ethanol,8 cm from anus)-treated rats recovered completely from the inflammation with acquired visceral hyperalgesia and EC cell hyperplasia at 4 wk after TNBS administration.CONCLUSION:TNBS dosage,concentration,intraco-lonic administration position,and ethanol percentage play important roles in developing visceral hyperalgesia and EC cell hyperplasia of TNBS-induced PI-IBS rats. | Hong-Yan Qin Hai-Tao Xiao Justin CY Wu Brian M Berman Joseph JY Sung Zhao-Xiang Bian | 2012 | World Journal of Gastroenterology2012，18，20： | 10 |
| 2 | Assessing keloid recurrence following surgical excision and radiation显示文摘Keloids are a fibroproliferative disorder that can result from a cutaneous injury to the reticular dermis.Recurrence rates as high as 100%have been reported following surgical excision alone.Consequently,a variety of post-surgical techniques have been employed to prevent keloid recurrence,including the use of radiation.Although numerous studies have shown post-excisional X-rays,electron beam,lasers and brachytherapy can reduce the rate of keloid recurrence,numerous inconsistencies,including a wide range of definitions for keloid recurrence,make it difficult to compare study outcomes.The review aims to examine the various means for defining keloid recurrence in clinical trials involving the use of radiation therapy.Searches of the Cochrane Library and PubMed were performed to identify the available information for post-surgical keloid recurrence following radiation therapy.Each identified study was reviewed for patient followup and criteria used to define keloid recurrence.The search results included clinical studies with external beam radiation,brachytherapy and superficial radiation therapy.Many studies did not include a definition of keloid recurrence,or defined recurrence only as the return of scar tissue.Other studies defined keloid recurrence based on patient self-assessment questionnaires,symptoms and scar elevation and changes in Kyoto Scar Scale,Japan Scar Workshop Scale and Vancouver Scar Scale scores.The results of this review indicate keloidectomy followed by radiation therapy provide satisfactory recurrence rates;however,clinical studies evaluating these treatments do not describe treatment outcomes or use different definitions of keloid recurrence.Consequently,recurrence rates vary widely,making comparisons across studies difficult.Keloid recurrence should be clearly defined using both objective and subjective measures. | Michael H.Gold Mark S.Nestor Brian Berman David Goldberg | 2020 | Burns & Trauma2020，8，1： | 8 |
| 3 | Diagnosis of gastrointestinal stromal tumors: A consensus approach显示文摘 | Christopher D.M. Fletcher Jules J. Berman Christopher Corless Fred Gorstein Jerzy Lasota B.Jack Longley Markku Miettinen Timothy J. O’Leary Helen Remotti Brian P. Rubin Barry Shmookler Leslie H. Sobin Sharon W. Weiss | 2002 | Human Pathology2002，，5： | 7 |
| 4 | The CT-STAT (Coronary Computed Tomographic Angiography for Systematic Triage of Acute Chest Pain Patients to Treatment) Trial显示文摘 | James A. Goldstein Kavitha M. Chinnaiyan Aiden Abidov Stephan Achenbach Daniel S. Berman Sean W. Hayes Udo Hoffmann John R. Lesser Issam A. Mikati Brian J. O’Neil Leslee J. Shaw Michael Y.H. Shen Uma S. Valeti Gilbert L. Raff | 2011 | Journal of the American College of Cardiology2011，，14： | 1 |
| 5 | The Epidemiology of Postpartum Hemorrhage in a Large, Nationwide Sample of Deliveries显示文摘 | Brian T. Bateman Mitchell F. Berman Laura E. Riley Lisa R. Leffert | 2010 | Anesthesia & Analgesia2010，，5： | 1 |
| 6 | Perioperative Acute Ischemic Stroke in Noncardiac and Nonvascular Surgery: Incidence, Risk Factors, and Outcomes显示文摘 | Brian T. Bateman H Christian Schumacher Shuang Wang Shahzad Shaefi Mitchell F. Berman | 2009 | Anesthesiology2009，，2： | 1 |
| 7 | Suppression of Ongoing Experimental Arthritis by a Chinese Herbal Formula (Huo-Luo-Xiao-Ling Dan) Involves Changes in Antigen-Induced Immunological and Biochemical Mediators of Inflammation显示文摘 | Ying-Hua Yang Rajesh Rajaiah David Y.-W Lee Zhongze Ma Hua Yu Harry H. S. Fong Lixing Lao Brian M. Berman Kamal D. Moudgil | 2010 | Evidence-Based Complementary and Alternative Medicine2010，，： | 1 |
| 8 | Diagnosis of gastrointestinal stromal tumors: A consensus approach显示文摘 | Christopher D.M. Fletcher Jules J. Berman Christopher Corless Fred Gorstein Jerzy Lasota B.Jack Longley Markku Miettinen Timothy J. O'Leary Helen Remotti Brian P. Rubin Barry Shmookler Leslie H. Sobin Sharon W. Weiss | 2002 | Human Pathology2002，，5： | 1 |
| 9 | Abstract B56 :Notch sig- naling in prostate cancer progression显示文摘 | FILIPE L F BRIAN S BERMAN D M | 2012 | Cancer Res2012，72，4： | 1 |
| 10 | Peripartum subarachnoid hemorrhage: nationwide data and institutional experience显示文摘 | Bateman Brian T Olbrecht Vanessa A Berman Mitchell F | 2012 | Anesthesiology2012，116，2： | 1 |
| 11 | Can peak systolic velocities be used for prediction of stroke in sickle cell anemia?显示文摘 | Anne Jones Suzanne Granger Don Brambilla Dianne Gallagher Elliott Vichinsky Gerald Woods Brian Berman Steve Roach Fenwick Nichols Robert J. Adams | 2005 | Pediatric Radiology2005，，1： | 1 |
| 12 | Risk of recurrent stroke in patients with sickle cell disease treated with erythrocyte transfusions显示文摘 | Charles H. Pegelow Robert J. Adams Virgil McKie Miguel Abboud Brian Berman Scott T. Miller Nancy Olivieri Elliott Vichinsky Winfred Wang Donald Brambilla | 1995 | The Journal of Pediatrics1995，，6： | 1 |
| 13 | NeuroAIDS, Drug Abuse, and Inflammation: Building Collaborative Research Activities显示文摘 | Joan W. Berman Monica J. Carson Linda Chang Brian M. Cox Howard S. Fox R. Gilberto Gonzalez Glen R. Hanson Kurt F. Hauser Wen-Zhe Ho Jau-Shyong Hong Eugene O. Major William F. Maragos Eliezer Masliah Justin C. McArthur Diane B. Miller Avindra Nath James P | 2006 | Journal of Neuroimmune Pharmacology2006，，4： | 1 |
| 14 | The CT-STAT (Coronary Computed Tomographic Angiography for Systematic Triage of Acute Chest Pain Patients to Treatment) Trial显示文摘 | James A. Goldstein Kavitha M. Chinnaiyan Aiden Abidov Stephan Achenbach Daniel S. Berman Sean W. Hayes Udo Hoffmann John R. Lesser Issam A. Mikati Brian J. O’Neil Leslee J. Shaw Michael Y.H. Shen Uma S. Valeti Gilbert L. Raff | 2011 | Journal of the American College of Cardiology2011，，14： | 1 |
| 15 | Acupuncture for Chronic Low Back Pain 显示文摘 | Brian M Berman | 2010 | New England Journal of Med2010，363，： | 1 |
| 16 | Diagnosis of gastrointestinal stromal tumors: A consensus approach显示文摘 | Christopher D.M. Fletcher Jules J. Berman Christopher Corless Fred Gorstein Jerzy Lasota B.Jack Longley Markku Miettinen Timothy J. O’Leary Helen Remotti Brian P. Rubin Barry Shmookler Leslie H. Sobin Sharon W. Weiss | 2002 | Human Pathology2002，，5： | 1 |
| 17 | The VIVA Trial: Vascular Endothelial Growth Factor in Ischemia for Vascular Angiogenesis显示文摘 | Timothy D. Henry Brian H. Annex George R. McKendall Michael A. Azrin John J. Lopez Frank J. Giordano P. K. Shah James T. Willerson Raymond L. Benza Daniel S. Berman C. Michael Gibson Alex Bajamonde Amy Chen Rundle Jennifer Fine Edward R. McCluskey | 2003 | Circulation: Journal of the American Heart Association2003，，10： | 1 |
| 18 | Interscan reproducibility of quantitative coronary plaque volume and composition from CT coronary angiography using an automated method显示文摘 | Annika Schuhbaeck Damini Dey Yuka Otaki Piotr Slomka Brian G. Kral Stephan Achenbach Daniel S. Berman Elliott K. Fishman Shenghan Lai Hong Lai | 2014 | European Radiology2014，，： | 1 |
| 19 | Acupuncture for chronic low back pain显示文摘 | Brian M Berman MD Helene M | 2010 | N Engl J Med2010，363，5： | 1 |
| 20 | Digital Preservation Lifecycle Management for Multi-media Collections 显示文摘 | Arcot Rajasekar Reagan Moore Fran Berman Brian Schottlaender | 2005 | Digital Libraries : Implementing Strategies and Sharing Experiences Lecture Notes in Computer Science2005，，3815： | 1 |
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