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| 1 | Biliary Drainage in Patients With Unresectable, Malignant Obstruction Where ERCP Fails: Endoscopic Ultrasonography-Guided Choledochoduodenostomy Versus Percutaneous Drainage显示文摘 | Everson L.A. Artifon Dayse Aparicio Jose B. Paione Simon K. Lo Andre Bordini Carolina Rabello Jose P. Otoch Kapil Gupta | 2012 | Journal of Clinical Gastroenterology2012，，9： | 5 |
| 2 | “Zero Ischemia” Partial Nephrectomy: Novel Laparoscopic and Robotic Technique显示文摘 | Inderbir S. Gill Manuel S. Eisenberg Monish Aron Andre Berger Osamu Ukimura Mukul B. Patil Vito Campese Duraiyah Thangathurai Mihir M. Desai | 2010 | European Urology2010，，1： | 3 |
| 3 | Endoscopic radiofrequency ablation for malignant biliary obstruction: a nationwide retrospective study of 84 consecutive applications显示文摘 | Werner Dolak Florian Schreiber Hubert Schwaighofer Michael Gschwantler Wolfgang Plieschnegger Alexander Ziachehabi Andreas Mayer Ludwig Kramer Andreas Kopecky Christiane Schrutka-K?lbl Gernot Wolkersd?rfer Christian Madl Frieder Berr Michael Trauner Andre | 2014 | Surgical Endoscopy2014，，3： | 3 |
| 4 | Imaging iron stores in the brain using magnetic resonance imaging显示文摘 | E. Mark Haacke Norman Y.C. Cheng Michael J. House Qiang Liu Jaladhar Neelavalli Robert J. Ogg Asadullah Khan Muhammad Ayaz Wolff Kirsch Andre Obenaus | 2005 | Magnetic Resonance Imaging2005，，1： | 3 |
| 5 | Functional analysis and drug response to zinc and D-penicillamine in stable ATP7B mutant hepatic cell lines显示文摘AIM: To study the effect of anti-copper treatment for survival of hepatic cells expressing different ATP7 B mutations in cell culture. METHODS: The most common Wilson disease(WD) mutations p.H1069 Q, p.R778 L and p.C271*, found in the ATP7 B gene encoding a liver copper transporter, were studied. The mutations represent major genotypes of the United States and Europe, China, and India, respectively. A human hepatoma cell line previously established to carry a knockout of ATP7 B was used to stably express WD mutants. m RNA and protein expression of mutant ATP7 B, survival of cells, apoptosis, and protein trafficking were determined.RESULTS: Low temperature increased ATP7 B protein expression in several mutants. Intracellular ATP7 B localization was significantly impaired in the mutants. Mutants were classified as high, moderate, and no survival based on their viability on exposure to toxic copper. Survival of mutant p.H1069 Q and to a lesser extent p.C271* improved by D-penicillamine(DPA) treatment, while mutant p.R778 L showed a pronounced response to zinc(Zn) treatment. Overall, DPA treatment resulted in higher cell survival as compared to Zn treatment; however, only combined Zn + DPA treatment fully restored cell viability. CONCLUSION: The data indicate that the basic impact of a genotype might be characterized by analysis of mutant hepatic cell lines. | Gursimran Chandhok Judit Horvath Annu Aggarwal Mohit Bhatt Andree Zibert Hartmut HJ Schmidt | 2016 | World Journal of Gastroenterology2016，22，16： | 3 |
| 6 | Polymorphisms Near IL28B and Serologic Response to Peginterferon in HBeAg-Positive Patients With Chronic Hepatitis B显示文摘 | Milan J. Sonneveld Vincent W.–S. Wong Andrea M. Woltman Grace L.H. Wong Yilmaz Cakaloglu Stefan Zeuzem Erik H.C.J. Buster Andre G. Uitterlinden Bettina E. Hansen Henry L.Y. Chan Harry L.A. Janssen | 2012 | Gastroenterology2012，，3： | 3 |
| 7 | Dietary copper triggers onset of fulminant hepatitis in the Long-Evans cinnamon rat model显示文摘AIM:To investigate the impact of dietary copper given at different time points on the onset of fulminant hepatitis. METHODS:The Long-Evans cinnamon (LEC) rat model of Wilson's disease (WD) was used to study the impact of high dietary copper (hCu) on the induction of fulminant hepatitis at early or late time points of life. High Cu diet was started in rat pups or in adults (month 5) for three months. Animals that received reduced dietary copper (rCu) throughout their lifetime served as a control. Hepatitis-associated serum markers (alanine aminotransferase, aspartate transaminase, bilirubin) were analyzed in animal groups receiving hCu or rCu. Liver copper content and liver histology were revealed at sacrifice. A set of 5 marker genes previously found to be affected in injured liver and which are related to angiogenesis (Vegfa), fat metabolism (Srebf1), ex-tracellular matrix (Timp1), oxidative stress (Hmox1), and the cell cycle (Cdkn1a) were analyzed by real-time polymerase chain reaction. RESULTS:Regardless of the time point when hCu was started, LEC rats (35/36) developed fulminant hepatitis and died. Animals receiving rCu (36/36) remained healthy, did not develop hepatitis, and survived long term without symptoms of overt disease, although liver copper accumulated in adult animals (477 ± 75 μg/g). With regard to start of hCu, onset of fulminant hepatitis was significantly (P < 0.001) earlier in adults (35 ± 9 d) that showed pre-accumulation of liver copper as compared to the pup group (77 ± 15 d). Hepatitis-associated serum markers, liver copper and liver histology, as well as gene expression, were affected in LEC rats receiving hCu. However, except for early and rapid onset of hepatitis, biochemical and molecular markers were similar at the early and late time points of disease. CONCLUSION:Rapid onset of fulminant hepatitis in asymptomatic LEC rats with elevated liver copper suggests that there is a critical threshold of liver copper which is important to trigger the course of WD. | Ramsi Siaj Vanessa Sauer Sandra Stppeler Hans-Ullrich Spiegel Gabriele Khler Andree Zibert Hartmut HJ Schmidt | 2012 | World Journal of Gastroenterology2012，18，39： | 3 |
| 8 | 菱沸石-粘土复合物在沥青精制中的应用(英文)显示文摘阿尔伯塔的油砂资源日益成为北美重要的战略性能源供给.本实验室通过采用碱性条件下在高岭土表面上组装菱沸石的方法,合成了新型的菱沸石-粘土复合材料,并证明此复合材料是比菱沸石更好的油砂沥青精制剂.XRD,SEM,TEM,N2物理吸附和XPS表面元素分析结果表明,菱沸石-粘土复合材料具有大体积烃类分子可及的独特的外表面,该复合材料不仅可降低油砂沥青的裂解反应温度,同时还可大幅度脱除沥青中的硫、氮、镍和钒等杂质. | 卞俊杰 Steven M.KUZNICKI William C.McCAFFREY Andree KOENIG Christopher C.H.LIN | 2008 | 催化学报2008，29，11： | 2 |
| 9 | Role of zoledronic acid in the prevention and treatment of osteoporosis显示文摘 | Louis-Georges Ste-Marie Louis-Georges Ste-Marie Andree Boucher Ages Rakel | 2011 | Clinical Interventions in Aging (default)2011，，： | 2 |
| 10 | The Clustering of Other Chronic Inflammatory Diseases in Inflammatory Bowel Disease: A Population-Based Study显示文摘 | Charles N. Bernstein Andre Wajda James F. Blanchard | 2005 | Gastroenterology2005，，3： | 2 |
| 11 | Effects of hydrogen peroxide and nitric oxide on both salt and heat stress tolerance in rice显示文摘 | Akio Uchida Andre T Jagendorf Takashi Hibino Teruhiro Takabe Tetsuko Takabe | 2002 | Plant Science2002，，3： | 2 |
| 12 | Evolutionary test environment for automatic structural testing显示文摘 | Joachim Wegener Andre Baresel Harmen Sthamer | 2001 | Information and Software Technology2001，，14： | 2 |
| 13 | Five-Year Subjective and Objective Results of Laparoscopic and Conventional Nissen Fundoplication: A Randomized Trial显示文摘 | Werner A. Draaisma Hilda G. Rijnhart-de Jong Ivo A. M. J. Broeders Andre J. P. M. Smout Edgar J. B. Furnee Hein G. Gooszen | 2006 | Annals of Surgery2006，，1： | 2 |
| 14 | Prevalence of intra-abdominal hypertension in critically ill patients: a multicentre epidemiological study显示文摘 | Manu L. N. G. Malbrain Davide Chiumello Paolo Pelosi Alexander Wilmer Nicola Brienza Vincenzo Malcangi David Bihari Richard Innes Jonathan Cohen Pierre Singer Andre Japiassu Elizabeth Kurtop Bart L. De Keulenaer Ronny Daelemans Monica Del Turco P. Cosimin | 2004 | Intensive Care Medicine2004，，5： | 2 |
| 15 | Random Comparison of Guaiac and Immunochemical Fecal Occult Blood Tests for Colorectal Cancer in a Screening Population显示文摘 | Leo G. van Rossum Anne F. van Rijn Robert J. Laheij Martijn G. van Oijen Paul Fockens Han H. van Krieken Andre L. Verbeek Jan B. Jansen Evelien Dekker | 2008 | Gastroenterology2008，，1： | 2 |
| 16 | Mesenchymal stem cell-derived exosomes increase ATP levels, decrease oxidative stress and activate PI3K/Akt pathway to enhance myocardial viability and prevent adverse remodeling after myocardial ischemia/reperfusion injury显示文摘 | Fatih Arslan Ruenn Chai Lai Mirjam B. Smeets Lars Akeroyd Andre Choo Eissa N.E. Aguor Leo Timmers Harold V. van Rijen Pieter A. Doevendans Gerard Pasterkamp Sai Kiang Lim Dominique P. de Kleijn | 2013 | Stem Cell Research2013，，3： | 2 |
| 17 | Mechanisms by which inflammation may increase intestinal cancer risk in inflammatory bowel disease显示文摘 | Pamela M.O’Connor Tamia K.Lapointe Paul L.Beck Andre G.Buret | 2010 | Inflamm Bowel Dis2010，，8： | 2 |
| 18 | Cyclic Analysis of Wood Shear Walls显示文摘 | Bryan Folz Andre Filiatrault | 2001 | Journal of Structural Engineering2001，，4： | 2 |
| 19 | Posttensioned Energy Dissipating Connections for Moment-Resisting Steel Frames显示文摘 | Constantin Christopoulos Andre Filiatrault Chia-Ming Uang Bryan Folz | 2002 | Journal of Structural Engineering2002，，9： | 2 |
| 20 | Prevalence of headache in Europe: a review for the Eurolight project显示文摘 | Lars Jacob Stovner Colette Andree | 2010 | The Journal of Headache and Pain2010，，4： | 2 |
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