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| 1 | Gastrointestinal function in intensive care patients: terminology, definitions and management. Recommendations of the ESICM Working Group on Abdominal Problems显示文摘 | Annika Reintam Blaser Manu L. N. G. Malbrain Joel Starkopf Sonja Fruhwald Stephan M. Jakob Jan Waele Jan-Peter Braun Martijn Poeze Claudia Spies | 2012 | Intensive Care Medicine2012，，3： | 4 |
| 2 | Gastrointestinal symptoms during the first week of intensive care are associated with poor outcome: a prospective multicentre study显示文摘 | Annika Reintam Blaser Martijn Poeze Manu L. N. G. Malbrain Martin Bj?rck Heleen M. Oudemans-van Straaten Joel Starkopf | 2013 | Intensive Care Medicine2013，，5： | 3 |
| 3 | Intra-abdominal hypertension and the abdominal compartment syndrome: updated consensus definitions and clinical practice guidelines from the World Society of the Abdominal Compartment Syndrome显示文摘 | Andrew W. Kirkpatrick Derek J. Roberts Jan Waele Roman Jaeschke Manu L. N. G. Malbrain Bart Keulenaer Juan Duchesne Martin Bjorck Ari Leppaniemi Janeth C. Ejike Michael Sugrue Michael Cheatham Rao Ivatury Chad G. Ball Annika Reintam Blaser Adrian Regli Zs | 2013 | Intensive Care Medicine2013，，7： | 2 |
| 4 | Effect of intra-abdominal pressure on respiratory function in patients undergoing ventral hernia repair显示文摘AIM: To determine the influence of intra-abdominal pressure(IAP) on respiratory function after surgical repair of ventral hernia and to compare two different methods of IAP measurement during the perioperative period. METHODS: Thirty adult patients after elective repair of ventral hernia were enrolled into this prospective study.IAP monitoring was performed via both a balloontipped nasogastric probe [intragastric pressure(IGP), Ci MON, Pulsion Medical Systems, Munich, Germany] and a urinary catheter [intrabladder pressure(IBP), Uno Meter Abdo-Pressure Kit, Uno Medical, Denmark] on five consecutive stages:(1) after tracheal intubation(AI);(2) after ventral hernia repair;(3) at the end of surgery;(4) during spontaneous breathing trial through the endotracheal tube; and(5) at 1 h after tracheal extubation. The patients were in the complete supine position during all study stages.RESULTS: The IAP(measured via both techniques) increased on average by 12% during surgery compared to AI(P < 0.02) and by 43% during spontaneous breathing through the endotracheal tube(P < 0.01). In parallel, the gradient between РаСО2 and Et CO2 [Р(а-et)CO2] rose significantly, reaching a maximum during the spontaneous breathing trial. The PаO2/Fi O2 decreased by 30% one hour after tracheal extubation(P = 0.02). The dynamic compliance of respiratory system reduced intraoperatively by 15%-20%(P < 0.025). At all stages, we observed a significant correlation between IGP and IBP(r = 0.65-0.81, P < 0.01) with a mean bias varying from-0.19 mm Hg(2SD 7.25 mm Hg) to-1.06 mm Hg(2SD 8.04 mm Hg) depending on the study stage. Taking all paired measurements together(n = 133), the median IGP was 8.0(5.5-11.0) mm Hg and the median IBP was 8.8(5.8-13.1) mm Hg. The overall r2 value( n = 30) was 0.76(P < 0.0001). Bland and Altman analysis showed an overall bias for the mean values per patient of 0.6 mm Hg(2SD 4.2 mm Hg) with percentage error of 45.6%. Looking at changes in IAP between the different study stages, we found an excellent concordance coefficient of 94.9% comparing IBP and IGP( n = 117).CONCLUSION: During ventral hernia repair, the IAP rise is accompanied by changes in Р(а-et)CO2 and PаO2/Fi O2-ratio. Estimation of IAP via IGP or IBP demonstrated excellent concordance. | Konstantin M Gaidukov Elena N Raibuzhis Ayyaz Hussain Alexey Y Teterin Alexey A Smetkin Vsevolod V Kuzkov Manu LNG Malbrain Mikhail Y Kirov | 2013 | World Journal of Critical Care Medicine2013，2，2： | 2 |
| 5 | Prevalence of intra-abdominal hypertension in critically ill patients: a multicentre epidemiological study显示文摘 | Manu L. N. G. Malbrain Davide Chiumello Paolo Pelosi Alexander Wilmer Nicola Brienza Vincenzo Malcangi David Bihari Richard Innes Jonathan Cohen Pierre Singer Andre Japiassu Elizabeth Kurtop Bart L. De Keulenaer Ronny Daelemans Monica Del Turco P. Cosimin | 2004 | Intensive Care Medicine2004，，5： | 2 |
| 6 | Prevalence of intra-abdominal hypertension in critically ill patients:a multicentre epidemiological study显示文摘 | Malbrain ML Chiumello D Pelosi P | 2004 | Intensive Care Med2004，30，5： | 1 |
| 7 | Incidence and prognosis of intraabdominal hypertension in a mixed population of critically ill patients:a multiple-center epidemiological study显示文摘 | Malbrain ML Chiumello D Pelosi P | | 0，，02： | 1 |
| 8 | Treatment of severe thallium intoxication显示文摘 | Malbrain ML Lambrecht GL Zandijk E | 1997 | J Toxicol Clin Toxicol1997，35，1： | 1 |
| 9 | Incidence and prognosis of intraabdominal hypertension in a mixed population of critically ill patients:a multiple-center epidemiological study显示文摘 | Malbrain ML Chiumello D Pelosi P | | 0，，02： | 1 |
| 10 | Assessing fluid responsiveness with the passive leg raising maneuver in patients with increased intra-abdominal pressure: Be aware that not all blood returns!显示文摘 | Manu L. N. G. Malbrain Daniel A. Reuter | 2010 | Critical Care Medicine2010，，9： | 1 |
| 11 | Incidence and prognosis of intraabdonfinal hypertension in a mixed population of critically ill patients: A multiple-center epidemiological study 显示文摘 | Malbrain ML Chiumello D Pelosi P el al | 2005 | Crit Care Med2005，33，2： | 1 |
| 12 | Different techniques to measure intra-abdominal pressure (IAP): time for a critical re-appraisal 显示文摘 | Malbrain ML | 2004 | Intensive Care Med2004，30，3： | 1 |
| 13 | Thrombocytopenia and prognosis in intensive care 显示文摘 | Vanderschueren S De Weerdt A Malbrain M | 2000 | Crit Care Med2000，28，6： | 1 |
| 14 | Throm- eytopenia and prognosis in intensive eare显示文摘 | Vanderschueren S Weerdt A Malbrain M | 2000 | Crit Care Med2000，28，2： | 1 |
| 15 | Prevalence of intra?abdominal hypertension in critically ill patients: a multicentre epi?demiological study显示文摘 | Malbrain ML Chiumello D Pelosi P | 2004 | Intensive Care Med2004，30，5： | 1 |
| 16 | Thrombocytopenia and prognosis in intensive care显示文摘 | Vanderschueren S De Weerdt A Malbrain M | 2000 | Crit Care Med2000，28，6： | 1 |
| 17 | Capillary leakage index as outcome predictor?显示文摘 | Malbrain ML Debaveye Y De Coninck J | 2001 | Intensive Care Med2001，27，2： | 1 |
| 18 | Acute intestinal distress syndrome: the importance of intra-abdominal pressure 显示文摘 | Malbrain ML Vidts W Ravyts M | 2008 | Minerva Anestesiol2008，74，11： | 1 |
| 19 | Thrombocytopenia and prognosis in intensive care显示文摘 | Vanderschueren S Weerdt A Malbrain M | 2000 | Care Med2000，28，： | 1 |
| 20 | Incidence and progno?sis of intraabdominal hypertension in a mixed population of critically ill patients: A multiple- center epidemiological study显示文摘 | Malbrain ML Chiumello D Pelosi P | 2005 | Crit Care Med2005，33，2： | 1 |
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