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| 1 | 青藏高原东缘活动构造显示文摘青藏高原东缘由岷山断块和龙门山构造带构成。以活动构造地貌学为主线,在解析该地区主干断裂晚第四纪以来活动的地质地貌表现的基础上,对一批断裂运动学和史前强震活动的定量数据进行分析研究,结果表明:在岷山断块中,虎牙断裂的平均左旋滑动速率为1.4 mm/a,垂直滑动速率为0.3 mm/a。岷江断裂的平均垂直滑动速率介于0.37 mm/a^0.53 mm/a之间,左旋位错量与垂直位错量大致相当;在龙门山构造带中,茂汶-汶川断裂、北川-映秀断裂和彭县-灌县断裂的平均垂直滑动速率均在1 mm/a左右,且几条主干断裂的右旋位错量与垂直位错量相当。结合震源机制解结果和GPS测量资料,建立晚新生代以来青藏高原东缘向南东方向逸出的构造变形模式。 | 周荣军 李勇 Alexander L Densmore Michael A Ellis 何玉林 王凤林 黎小刚 | 2006 | 矿物岩石2006，26，2： | 141 |
| 2 | Anti-inflammatory properties of the short-chain fatty acids acetate and propionate:A study with relevance to inflammatory bowel disease显示文摘AIM: To compare the anti-inflammatory properties of butyrate with two other SCFAs,namely acetate and propionate,which have less well-documented effects on inflammation. METHODS: The effect of SCFAs on cytokine release from human neutrophils was studied with ELISA. SCFA-dependent modulation of NF-κB reporter activity was assessed in the human colon adenocarcinoma cell line,Colo320DM. Finally,the effect of SCFAs on gene expression and cytokine release,measured with RT-PCR and ELISA,respectively,was studied in mouse colon organ cultures established from colitic mice. RESULTS: Acetate,propionate and butyrate at 30 mmol/L decreased LPS-stimulated TNFα release from neutrophils,without affecting IL-8 protein release. All SCFAs dose dependently inhibited NF-κB reporter activity in Colo320DM cells. Propionate dose-dependently suppressed IL-6 mRNA and protein release from colon organ cultures and comparative studies revealed that propionate and butyrate at 30 mmol/L caused a strong inhibition of immune-related gene expression,whereas acetate was less effective. A similar inhibition was achieved with the proteasome inhibitor MG-132,but not the p38 MAPK inhibitor SB203580. All SCFAs decreased IL-6 protein release from organ cultures. CONCLUSION: In the present study propionate and butyrate were equipotent,whereas acetate was less effective,at suppressing NF-κB reporter activity,immune-related gene expression and cytokine release in vitro. Our findings suggest that propionate and acetate,in addition to butyrate,could be useful in the treatment of inflammatory disorders,including IBD. | Sofia Tedelind Fredrik Westberg Martin Kjerrulf Alexander Vidal | 2007 | World Journal of Gastroenterology2007，13，20： | 81 |
| 3 | 龙门山地震带的地质背景与汶川地震的地表破裂显示文摘龙门山位于青藏高原与扬子地台之间,系由一系列大致平行的叠瓦状冲断带构成,自西向东发育汶川—茂汶断裂、映秀—北川断裂和彭县—灌县断裂,并将龙门山划分为3个构造地层带,分别为变形变质构造地层带(主要由志留系—泥盆系浅变质岩和前寒武系杂岩构成)、变形变位构造地层带(主要由上古生界—三叠系沉积岩构成)、变形构造地层带(主要由侏罗系至第三系红层和第四纪松散堆积构成)。龙门山断裂带属地震危险区,3条主干断裂皆具备发生7级左右地震的能力,其中映秀—北川断裂是引发地震的最主要断层,据对彭县—灌县断裂青石坪探槽场地的研究结果表明,在该断裂带上最晚的一次强震发生在930±40a.B.P.左右,据此,可以初步判定,这3条主干断裂的单条断裂上的强震复发间隔至少应在1000a左右,表明龙门山构造带及其内部断裂属于地震活动频度低但具有发生超强地震的潜在危险的特殊断裂,以逆冲-右行走滑为其主要运动方式。汶川地震属于逆冲—走滑型的地震,地表破裂分布于映秀—北川断裂带和彭县—灌县断裂带上。根据近南北向的断裂(小鱼洞断层、擂鼓断层和邓家坝断层)和地表断距可将映秀—北川断层的地表破裂带划分为两个高值区和两个低值区,两个高值区分别位于南段的映秀-虹口一带和位于中北段的擂鼓—北川县城—邓家坝一带;两个低值区分别位于中南段的白水河—茶坪一带和北段的北川黄家坝至平武石坎子一带,两个高值区分别与小鱼洞断层和擂鼓断层相关。根据保存于破裂面上的擦痕,可将该地震破裂过程划分为两个阶段,早期为逆冲作用,晚期为斜向走滑作用,其与地壳增厚构造模式和侧向挤出摸式在青藏高原东缘的推论具有不吻合性。鉴于龙门山的表层运动速率与深部构造运动速率具有不一致性,初步探讨了龙门山地区的地表过程与下地壳流之间的地质动力模型,认为下地壳物质在龙门山近垂向挤出和垂向运动,从而造成导致龙门山向东的逆冲运动、龙门山构造带抬升和汶川特大地震。在此基础上,根据汶川地震所引发的地质灾害,对地震灾后重建提出了的几点建议。 | 李勇 黄润秋 周荣军 Alexander L.DENSMORE Michael A.ELLIS 闫亮 董顺利 Nicholas RICHARDSON 张毅 何玉林 陈浩 乔宝成 马博琳 | 2009 | 工程地质学报2009，17，1： | 108 |
| 4 | 急性缺血性卒中静脉阿替普酶溶栓治疗的纳入和排除标准的科学依据美国心脏协会/美国卒中协会对医疗卫生专业人员发布的声明(续前)显示文摘19 颅内出血史
根据最初的 FDA 标签和2013年AHA/ASA指南,颅内出血史是静脉阿替普酶治疗缺血性卒中的一项额外禁忌证或排除标准。最近修订后的标签仅将近期 ICH 列为一项警告,并且在禁忌证中删除了ICH史。与前面讨论的静脉阿替普酶治疗排除标准相似,文献回顾仅在大样本回顾性研究中发现了少量这类病例。缺乏相关数据可能是修订后的FDA 标签不再将 ICH 史作为禁忌证而仅将近期ICH 列为一项警告的原因。在这种情况下,FDA 如何定义“近期”一词尚不清楚。有趣的是,对在静脉阿替普酶治疗前通过 MRI 检测脑微出血( cerebral microbleed, CMBs)存在情况进行的研究可为这个卒中亚组患者提供更多的见解。从病理生理学角度,这种微出血的原因尚不清楚,可能反映再灌注损伤或脑血管自动调节功能破坏。因此,在静脉阿替普酶治疗后出现这些损害可能没有意义或是人为信号。 | Dawn O. Kleindorfer Opeolu M. Adeoye Andrew M. Demchuk Jennifer E. Fugate James C. Grotta Alexander A. Khalessi Elad I. Levy Yuko Y. Palesch Shyam Prabhakaran Gustavo Saposnik Jeffrey L. Saver Eric E. Smith 高圆圆 顾雨铖 徐欣 徐曼曼 张佳慧 李韶雅 冒萧萧 陈歆 徐运 | 2016 | 国际脑血管病杂志2016，24，5： | 98 |
| 5 | Adverse events with bismuth salts for Helicobacter pylori eradication:Systematic review and meta-analysis显示文摘AIM: To assess the safety of bismuth used in Helico- bacter pylori (H pylori) eradication therapy regimens. METHODS: We conducted a systematic review and meta-analysis. MEDLINE and EMBASE were searched (up to October 2007) to identify randomised controlled tri- als comparing bismuth with placebo or no treatment, or bismuth salts in combination with antibiotics as part of eradication therapy with the same dose and duration of antibiotics alone or, in combination, with acid suppres- sion. Total numbers of adverse events were recorded. Data were pooled and expressed as relative risks with 95% confidence intervals (CI). RESULTS: We identified 35 randomised controlled tri- als containing 4763 patients. There were no serious adverse events occurring with bismuth therapy. There was no statistically significant difference detected in total adverse events with bismuth [relative risk (RR) = 1.01; 95% CI: 0.87-1.16], specific individual adverse events, with the exception of dark stools (RR = 5.06; 95% CI: 1.59-16.12), or adverse events leading to withdrawal of therapy (RR = 0.86; 95% CI: 0.54-1.37). CONCLUSION: Bismuth for the treatment of H pylori is safe and well-tolerated. The only adverse event oc- curring significantly more commonly was dark stools. | Alexander C Ford Peter Malfertheiner Monique Giguère José Santana Mostafizur Khan Paul Moayyedi | 2008 | World Journal of Gastroenterology2008，14，48： | 62 |
| 6 | Current and future treatments for hepatocellular carcinoma显示文摘Hepatocellular carcinoma(HCC) represents a unique challenge for physicians and patients.There is no definitively curative treatment.Rather,many treatment and management modalities exist with differing advantages and disadvantages.Both current guidelines and individual patient concerns must be taken into account in order to properly manage HCC.In addition,quality of life issues are particularly complex in patients with HCC and these concerns must also be factored into treatment strategies.Thus,considering all the options and their various pros and cons can quickly become complex for both clinicians and patients.In this review,we systematically discuss the current treatment modalities available for HCC,detailing relevant clinical data,risks and rewards and overall outcomes for each approach.Surgical options discussed include resection,transplantation and ablation.We also discuss the radiation modalities:conformal radiotherapy,yttrium 90 microspheres and proton and heavy ion radiotherapy.The biologic agent Sorafenib is discussed as a promising new approach,and recent clinical trials are reviewed.We then detail currently described molecular pathways implicated in the initiation and progression of HCC,and we explore the potential of each pathway as an avenue for drug exploitation.We hope this comprehensive and forward-looking review enables both clinicians and patients to understand various options and thereby make more informed decisions regarding this disease. | Alexander Schlachterman Willie W Craft Jr Eric Hilgenfeldt Avir Mitra Roniel Cabrera | 2015 | World Journal of Gastroenterology2015，21，28： | 76 |
| 7 | 新生儿肺炎死亡病例中B族链球菌的检测显示文摘目的对北京儿童医院新生儿肺炎死亡病例进行B族链球菌(GBS)回顾性检测,旨在初步揭示GBS感染在新生儿重症肺炎中的地位。方法收集200例1953年到2004年间新生儿肺炎死亡病例(研究组)和34例非感染性疾病新生儿死亡病例(对照组)的尸检病理标本,提取石蜡组织DNA,通过PCR和Southernblot技术检测GBS特异性基因片断cfb基因。同时对所选病例的临床资料进行复习。结果(1)研究组200例中,PCR对GBS检出率为26%,Southernblot检出率为65%,检出率均明显高于对照组(PCR3%,χ2=8.82,P<0.01;Southernblot,18%,χ2=26.77,P<0.01)。(2)研究组中,年龄小于7d的病例(早发型)103例,年龄大于7d的病例(晚发型)97例,小于7d的患儿GBS检出率明显高于大于7d的患儿,其中PCR检出率在前者为37%,后者为13%(χ2=15.537,P<0.01),Southernblot检出率在前者为72%,后者为52%(χ2=4.37,P<0.05)。早发型阳性病例中,39%为早产儿(29/74)。(3)研究组中,75例有完整临床资料,其中35例可查到一项或多项与GBS感染有关的危险因素,如早产,低体重,胎膜早破,羊水异常等,GBS检测结果均为阳性。阳性病例中,早发型最常见的表现有青紫、窒息,呼吸困难,晚发型最常见的表现有咳喘,呼吸困难。对照组中,1例PCR检测阳性者患恶性畸胎瘤,其他5例仅Southernblot检测阳性者分别为核黄疸、肝癌、先天性无肛合并膀胱尿道瘘、新生儿自然出血、先天性低位无肛合并直肠会阴瘘患者。结论GBS是新生儿肺炎死亡病例中的重要病原,尤其在早发型肺炎病例中GBS感染占很大比重。Southernblot是在石蜡标本中检测GBS的较为敏感方法。 | 邓江红 姚开虎 胡惠丽 俞桑洁 高薇 伏利兵 何乐健 Alexander Dmitriev 杨永弘 | 2006 | 中华儿科杂志2006，44，11： | 53 |
| 8 | 映秀-北川断裂的地表破裂与变形特征显示文摘2008年5月12日在龙门山映秀-北川断裂带发生的8.0级特大地震,属于逆冲—走滑型地震。本文以地表破裂为切入点,在映秀-北川断裂的关键部位开展了详细的野外地貌测量,标定了映秀-北川断裂带的垂向断距和水平断距,结果表明映秀-北川断裂的地表破裂带从映秀向北东延伸达180~190km,走向介于NE30°~50°之间,倾向北西,地表平均垂向断距为2.9m,平均水平断距为3.1m;地表最大错动量的地点位于北川县擂鼓镇,垂直断错为6.2±0.1m,水平断错为6.8±0.2m,逆冲分量与右行走滑分量的比值为3∶1~1∶1,表明该断裂以逆冲—右行走滑为特点,逆冲运动分量略大于或等于右行走滑运动分量。根据近南北向的分段断裂可将映秀-北川断层的地表破裂带划分为两个高值区和两个低值区,其中两个高值区分别位于南段的映秀—虹口一带和中北段的擂鼓—北川县城—邓家坝一带。基于保存于破裂面上的擦痕,我们将该地震破裂过程划分为两个阶段,早期为逆冲作用,晚期为斜向走滑作用。 | 李勇 周荣军 Alexander L.DENSMORE 闫亮 Nicholas RICHARDSON 董顺利 Michael A.ELLIS 张毅 何玉林 陈浩 乔宝成 马博琳 | 2008 | 地质学报2008，82，12： | 58 |
| 9 | 香港华人妇女产后抑郁危险因素的前瞻性研究显示文摘目的:产后抑郁是一种常见的精神障碍,对产妇、新生儿和其它家庭成员导致广泛的伤害。产后抑郁的病因学研究大多是基于西方样本,对其中的社会文化原因也缺乏实证研究。本研究从人口学、心理社会及种族文化因素等方面探讨中国妇女产后抑郁症状学的决定因素。方法:在大学附属综合医院产前门诊连续收集登记的中国孕妇959例,从她们第一次产前检查开始评估(基线),以后分别在孕期的最后3个月、产后即刻和产后3个月时评估。调查涉及的危险因素分6个方面:人口学和社会经济背景,躯体疾病及精神疾病病史, 产前抑郁情绪,围生期应激源,人际关系,和种族文化环境。采用等级回归进行分析。因变量是产后3个月时的抑郁评分。结果:决定产后抑郁症状学的因素有:目前的生活事件,缺乏社会支持,婚姻不满意,既往有故意自伤史,以及产前存在抑郁情绪。婆媳关系不好和没有陪月在产后阶段也与抑郁评分高有关联。结论:西方研究所确立的产后抑郁危险因素大体适用于中国妇女。产褥期的社会文化特点同样对产妇情绪有影响。 | Dominic TS Lee Alexander SK Yip Sandra SM Chan Fiona FY Lee Tony YS Leung Tony KH Chung | 2005 | 中国心理卫生杂志2005，19，9： | 50 |
| 10 | A community-derived classification for extant lycophytes and ferns显示文摘发展史长通知了蕨类植物分类。当我们推断进化的树的能力改善了,针对认出生来的组的分类变得逐渐地预兆、稳定。这里,我们为 lycophytes 和蕨纲植物提供一个现代、全面分类,在下面,利用一条基于社区的途径类水平。我们 monophyly 用作主要标准让 taxa,而且目的识别保存两个广泛地被接受的存在 taxa 和界限并且与我们蕨类植物发展史的理解一致。总共,这个分类对待一在 337 个类, 51 个家庭, 14 目,和二个班估计了 11 916 种类。这个分类没在 lycophyte 和蕨纲植物上作为最后的词被打算分类,而是当前的假设的概括陈述,源于最好的可得到的数据并且在问题由熟悉植物的那些大多数塑造了。我们希望它将在蕨类植物上为最近的文学的那些想要的参考用作一个资源发展史和分类,为指导未来调查的一个框架,和推进讲话的刺激。 | Eric Schuettpelz Harald Schneider Alan R. Smith Peter Hovenkamp Jefferson Prado Germinal Rouhan Alexandre Salino Michael Sundue Thafs Elias Almeida Barbara Parris Emily B. Sessa Ashley R. Field Andre Luis de Gasper Carl J. Rothfels Michael D. Windham Marcus Lehnert Benjamin Dauphin Atsushi Ebihara Samuli Lehtonen Pedro Bond Schwartsburd Jordan Metzgar Li-Bing Zhang Li-Yaung Kuo Patrick J. Brownsey Masahiro Kato Marcelo Daniel Arana Francine C. Assis Michael S. Barker David S. Barrington Ho-Ming Chang Yi-Han Chang Yi-Shan Chao Cheng-Wei Chen De-Kui Chen Wen-Liang Chiou Vinicius Antonio de Oliveira Dittrich Yi-Fan Duan Jean-Yves Dubuisson Donald R. Farrar Susan Fawcett Jose Maria Gabriel y Galan Luiz Armando de Araujo Goes-Neto Jason R. Grant Amanda L. Grusz Christopher Haufler Warren Hauk Hai He Sabine Hennequin Regina Yoshie Hirai Layne Huiet Michael Kessler Petra Korall Paulo H. Labiak Anders Larsson Blanca Leen Chun-Xiang Li Fay-Wei Li Melanie Link-Perez Hong-Mei Liu Ngan Thi Lu Esteban I. Meza-Torres Xin-Yuan Miao Robbin Moran Claudine Massi Mynssens Nathalie Nagalingum Benjamin Ollgaard Alison M. Paul Jovani B. de S. Pereira Leon R. Perrie Monica Ponce Tom A. Ranker Christian Schulz Wataru Shinohara Alexander Shmakov Erin M. Sigel Filipe Soares de Souza Lana da Silva Sylvestre Weston Testo Luz Amparo Triana-Moreno Chie Tsutsumi Hanna Tuomisto IvAn A. Valdespino Alejandra Vasco Raquel Stauffer Viveros Alan Weakley Ran Wei Stina Weststrand Paul G. Wolf George Yatskievych Xiao-Gang Xu Yue-Hong Yan Liang Zhang Xian-Chun Zhang Xin-Mao Zhou | 2016 | Journal of Systematics and Evolution2016，54，6： | 44 |
| 11 | 贝叶斯因子及其在JASP中的实现显示文摘统计推断在科学研究中起到关键作用,然而当前科研中最常用的经典统计方法——零假设检验(Null hypothesis significance test,NHST)却因难以理解而被部分研究者误用或滥用。有研究者提出使用贝叶斯因子(Bayes factor)作为一种替代和(或)补充的统计方法。贝叶斯因子是贝叶斯统计中用来进行模型比较和假设检验的重要方法,其可以解读为对零假设H_0或者备择假设H_1的支持程度。其与NHST相比有如下优势:同时考虑H_0和H_1并可以用来支持H_0、不'严重'地倾向于反对H_0、可以监控证据强度的变化以及不受抽样计划的影响。目前,贝叶斯因子能够很便捷地通过开放的统计软件JASP实现,本文以贝叶斯t检验进行示范。贝叶斯因子的使用对心理学研究者来说具有重要的意义,但使用时需要注意先验分布选择的合理性以及保持数据分析过程的透明与公开。 | 胡传鹏 孔祥祯 Eric-Jan Wagenmakers Alexander Ly 彭凯平 | 2018 | 心理科学进展2018，26，6： | 41 |
| 12 | 天山现今地壳运动的形变场分析显示文摘对天山地区GPS测量成果进行系统处理,获得了整体天山相对于欧亚大陆的现今地壳运动的212个GPS站速度场结果,再现了受印度板块向北推挤作用下天山地区相对欧亚板块的水平构造变形分布状态。天山地区GPS速度场表明,天山地壳缩短由南向北、由西向东递减,表明板块的推挤作用力随着天山的褶皱变形相应减弱;西天山的变形强于东天山的主要原因可能是西部帕米尔高原对天山的直接俯冲推挤作用的结果;而东天山的构造活动则是塔里木块体对其缓慢推挤的结果。 | 王晓强 李杰 王琪 Alexander Zubovich | 2005 | 大地测量与地球动力学2005，25，3： | 39 |
| 13 | 利用GPS形变资料研究天山及邻近地区地壳水平位移与应变特征显示文摘以天山及邻近地区的230个GPS观测站长期水平运动速率为基础,计算并绘制了该地区GPS站速度场及地壳水平应变场分布图,得到了以下结论:在以欧亚板块为参考基准的背景下,天山及邻近地区GPS速度场表明,天山地壳缩短方式由南向北,以东经77°±1°(北纬38°~42°)为界向两侧逐渐递减;同时表明,板块的推挤作用力随着天山的褶皱变形减小相应趋缓.天山及邻近地区的主压应变方向分布近北北西向,基本与天山山体走向正交.反映了在印度板块碰撞推挤的强烈构造运动影响下天山及邻近地区的最大主应力分布与变化情况.其最大剪应变场集中分布在两个区域:北天山的吉尔吉斯斯坦依赛克湖附近;南天山伽师与帕米尔弧形断裂交会地带.整个地区多年来的地震震中分布,反映了该区域大地震通常发生在剪应变高值区或其边缘地带. | 王晓强 李杰 Alexander Zubovich 王琪 | 2007 | 地震学报2007，29，1： | 35 |
| 14 | Active Tectonics of the Longmen Shan Region on the Eastern Margin of the Tibetan Plateau显示文摘有为在在西藏的高原的东方边缘的 theLongmen 掸人的活跃 tectonics 的似地球形状的证据的巨大的数量。我们包括 Wenchuan-Maowen, Beichuan-Yingxiu 和 Pengxian-Guanxian 差错调查了一些典型似地球形状的标记,平台偏移量,陡坡,控制差错的僵绳,右快门山脉,右隧道偏移量,抓住在,粉碎带,和拉开盆。电子自旋共振(ESR ) 和热照明(TL ) 变老用从在沉积的表面下面拿的淤泥的沙被获得。根据这些数据,我们推测推进和走向滑倒的率,和结果显示在高原边缘弄短的 Cenozoictectonic 与插入不到 1.10 mm/aand 的率是次要的率滑倒罢工不到 1.46 mm/a。Longmen 掸人是 NNE-trendingdextral 的一个地区与 6:1-1.3:1 的滑倒剧降比率砍。从 NW 到 SE,戳部件变得更小,而走向滑倒部件变得更大。 | ZHOU Rongjun LI Yong Alexander L.DENSMORE Michael A. ELLIS HE Yulin LI Yongzhao LI Xiaogang | 2007 | Acta Geologica Sinica(English Edition)2007，81，4： | 37 |
| 15 | Diagnosis of biliary strictures after liver transplantation:Which is the best tool?显示文摘AIM: To evaluate the diagnostic value of different indirect methods like biochemical parameters, ultrasound (US) analysis, CT-scan and MRI/MRCP in comparison with endoscopic retrograde cholangiography (ERC), for diagnosis of biliary complications after liver transplantation. METHODS: In 75 patients after liver transplantation, who received ERC due to suspected biliary complications, the result of the cholangiography was compared to the results of indirect imaging methods performed prior to ERC. The cholangiography showed no biliary stenosis (NoST) in 25 patients, AST in 27 and ITBL in 23 patients. RESULTS: Biliary congestion as a result of AST was detected with a sensitivity of 68.4% in US analysis (specificity 91%), of 71% in MRI (specificity 25%) and of 40% in CT (specificity 57.1%). In ITBL, biliary congestion was detected with a sensitivity of 58.8% in the US, 88.9%in MRI and of 83.3% in CT. However, as anastomotic or ischemic stenoses were the underlying cause of biliary congestion, the sensitivity of detection was very low. InMRI detected the dominant stenosis at a correct localization in 22% and CT in 10%, while US failed completely. The biochemical parameters, showed no significant difference in bilirubin (median 5.7; 4,1; 2.5 mg/dL), alkaline phosphatase (median 360; 339; 527 U/L) or gamma glutamyl transferase (median 277; 220; 239 U/L) levels between NoST, AST and ITBL.CONCLUSION: Our data confirm that indirect imaging methods to date cannot replace direct cholangiography for diagnosis of post transplant biliary stenoses. However MRI may have the potential to complement or precede imaging by cholangiography. Optimized MRCP-processing might further improve the diagnostic impact of this method. | Thomas Zoepf Evelyn J. Maldonado-Lopez Philip Hilgard Alexander Dech■ne Massimo Malago Christoph E. Broelsch Joerg Schlaak Guido Gerken | 2005 | World Journal of Gastroenterology2005，11，19： | 32 |
| 16 | Active Tectonics and Erosional Unloading at the Eastern Margin of the Tibetan Plateau显示文摘The eastern margin of the Tibetan Plateau is marked by an extremely steep mountain front with relief of over 5 km. This topography,coupled with abundant Mesozoic thrusts within the margin,explains why tectonic maps of the India-Asia collision typically show the eastern margin as a major thrust zone. Actually,it does not like that. Field observations suggest that the margin is better characterized as a zone of NNE-directed dextral shear with extensive strike-slip faulting and secondary thrusting. The high relief and steep gradients are partially explained by erosional unloading of an elastic lithosphere;the pre-erosion inherited topography may be the inherited Mesozoic thrust belt landscape modified by a component of Cenozoic tectonic shortening. | Alexander L. Densmore LI Yong Michael A. Ellis ZHOU Rongjun | 2005 | Journal of Mountain Science2005，2，2： | 34 |
| 17 | 汶川8.0级地震的基本特征及其研究进展显示文摘2008年5月12日在龙门山发生的汶川8.0级特大地震属于逆冲—走滑型地震。为了尽快和最好地利用汶川地震的资料,推动地震地质科学的研究。在论述了汶川地震科学研究的基本现状和研究进展的基础上,重点讨论了龙门山地震带的地质背景、活动构造、汶川地震的基本特征、地表破裂及组合样式、历史强地震复发周期、观测数据的积累与整合、构造运动学和动力学机制、地质灾害和灾后重建、龙门山地区未来地震的预测和预报等方面的内容。并建议从汶川大地震中汲取教训,整合地质学、地球物理和地球化学等多学科的综合研究,探讨汶川地震的形成过程和机制,以有效地减轻和逐步避免今后可能发生的类似的灾难。 | 李勇 黄润秋 DENSMORE Alexander L. 周荣军 曹叔尤 | 2009 | 四川大学学报(工程科学版)2009，0，3： | 32 |
| 18 | 陈皮挥发油的气相色谱/质谱分析显示文摘用GCIMS分析复方制剂平胃散中的一种单味药材陈皮的挥发油化学成分及其相对含量,对色质联用仪产生的二维数据借助直观推导式演进特征投影(HEIP)法来分辨以得到组分的纯色谱和质谱,根据组分的色谱保留时间和质谱对组分进行定性,继而用总体积积分法定量。本文分离出53个组分,其中鉴定了34个组分,约占其挥发油总量的96.08%。 | 龚范 梁逸曾 宋又群 彭源贵 崔卉 Leung Alexander Kai-man Chau Foo-tim | 2000 | 分析化学2000，28，7： | 32 |
| 19 | Varicocele and testicular function显示文摘阴囊的精索静脉曲张, pampiniform 丛的静脉的膨胀想了经由静脉的拥挤增加阴囊的温度,通常与男不孕被联系。重要学习在精液参数上澄清了精索静脉曲张的否定影响,更最近的工作有使它的有害效果清楚些在上分子并且精子和阴囊的微型环境的 ultrastructural 特征,以及更多清楚地在 couples’ 上定义处理的积极影响;富饶。当有一段时间基于 histologic 评估知道时,在精索静脉曲张和阴囊的内分泌的功能之间的关系与在精索静脉曲张和性腺机能减退之间的一个成长连接在临床的设置变得更明显。在小儿科的背景,当未来学习将在富饶和阴囊的功能上澄清精索静脉曲张的影响时,最后,最近的工作在青少年和成年人支持精索静脉曲张的平行效果,建议当前的治疗的重新评估考虑到条件的进步性质和未来疾病的潜在的增加的风险来临。 | Alexander W Pastuszak | 2015 | Asian Journal of Andrology2015，17，4： | 32 |
| 20 | MicroRNAs as non-invasive diagnostic biomarkers for gastric cancer:Current insights and future perspectives显示文摘Non-invasive diagnostic biomarkers may contribute to an early identification of gastric cancer(GC) and improve the clinical management.Unfortunately,no sensitive and specific screening biomarkers are available yet and the currently available approaches are limited by the nature of the disease.GC is a heterogenic disease with various distinct genetic and epigenetic events that occur during the multifactorial cascade of carcinogenesis.Micro RNAs(mi RNAs) are commonly deregulated in gastric mucosa during the Helicobacter pylori infection and in stepwise manner from chronic gastritis,through preneoplastic conditions such as atrophic gastritis and intestinal metaplasia,to early dysplasia and invasive cancer.Identification of mi RNAs in blood in 2008 led to a great interest on mi RNA-based diagnostic,prognostic biomarkers in GC.In this review,we provide the most recent systematic review on the existing studies related to mi RNAs as diagnostic biomarkers for GC.Here,we systematically evaluate 75 studies related to differential expression of circulating mi RNAs in GC patients and provide novel view on various heterogenic aspects of the existing data and summarize the methodological differences.Finally,we highlight several important aspects crucial to improve the future translational and clinical research in the field. | Alexander Link Juozas Kupcinskas | 2018 | World Journal of Gastroenterology2018，24，30： | 32 |
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