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| 1 | The Ozone Component of Global Change:Potential Effects on Agricultural and Horticultural Plant Yield,Product Quality and Interactions with Invasive Species显示文摘The productivity,product quality and competitive ability of important agricultural and horticultural plants in many regions of the world may be adversely affected by current and anticipated concentrations of ground-level ozone(O3).Exposure to elevated O3 typically results in suppressed photosynthesis,accelerated senescence,decreased growth and lower yields.Various approaches used to evaluate O3 effects generally concur that current yield losses range from 5% to 15% among sensitive plants.There is,how-ever,considerable genetic variability in plant responses to O3.To illustrate this,we show that ambient O3 concentrations in the eastern United States cause substantially different levels of damage to otherwise similar snap bean cultivars.Largely undesirable effects of O3 can also occur in seed and fruit chemistry as well as in forage nutritive value,with consequences for animal production.Ozone may alter herbicide efficacy and foster estab-lishment of some invasive species.We conclude that current and projected levels of O3 in many regions worldwide are toxic to sensitive plants of agricultural and horticultural significance.Plant breeding that incorporates O3 sensitivity into selection strategies will be increasingly necessary to achieve sustainable production with changing atmospheric composition,while reductions in O3 precursor emissions will likely benefit world food pro-duction and reduce atmospheric concentrations of an important greenhouse gas. | Fitzgerald Booker Russell Muntifering Margaret McGrath Kent Burkey Dennis Decoteau Edwin Fiscus William Manning Sagar Krupa Arthur Chappelka David Grantz | 2009 | Journal of Integrative Plant Biology2009，51，4： | 18 |
| 2 | 国际糖尿病足工作组:糖尿病足溃疡分类指南——《国际糖尿病足工作组:糖尿病足防治国际指南(2019)》的一部分显示文摘国际糖尿病足工作组(IWGDF)自1999年以来一直以循证为基础发布糖尿病足病的预防和管理指南。本文中针对日常临床工作中糖尿病足溃疡的分类提出了新指南,并对既有的分类进行了综述。新指南只对现患糖尿病足溃疡进行分类,不包括用于定义未来溃疡风险的分类系统。本指南的制定是基于对现有文献的综述以及专家对最大程度影响临床结局的8个关键因素的鉴定。分类级别是根据关键因素的数量、内部和外部有效性验证以及使用意向而制定的。判定分类评分的关键因素有3种:患者相关的因素(终末期肾衰竭)、肢体相关的因素(周围动脉病变和保护性感觉丧失)和溃疡相关的因素(面积、深度、部位、单发或多发以及感染)。特殊分类系统要考虑以下5种临床情况:①卫生专业人员之间交流;②预测单个溃疡预后;③对个案临床决策的辅助;④伤口评估,有感染或无感染及周围动脉病变(评估灌注及血管重建的潜在益处);⑤用于地方、区域或国家人群结局的稽查。指南推荐:①医务人员之间交流使用SINBAD系统。②无适用于预测个体溃疡预后的分类。③感染的评估采用美国传染病学会/国际糖尿病足工作组(IDSA/IWGDF)分类系统。④评估灌注及血管重建的潜在获益使用创面、缺血、足感染(WIfI)系统。⑤人群结局的稽查使用SINBAD系统。 | Matilde Monteiro-Soares David Russell Edward J Boyko William Jeffcoate Joseph L Mills Stephan Morbach Fran Game 无 王爱红(译) 冉兴无(审校) | 2019 | 感染.炎症.修复2019，20，4： | 10 |
| 3 | Clinical Performance of an Automated Stool DNA Assay for Detection of Colorectal Neoplasia显示文摘 | Graham P. Lidgard Michael J. Domanico Janelle J. Bruinsma James Light Zubin D. Gagrat Rebecca L. Oldham-Haltom Keith D. Fourrier Hatim Allawi Tracy C. Yab Julie A. Simonson Mary Devens Russell I. Heigh David A. Ahlquist Barry M. Berger | 2013 | Clinical Gastroenterology and Hepatology2013，，： | 5 |
| 4 | Particulate Matter Air Pollution and Cardiovascular Disease: An Update to the Scientific Statement From the American Heart Association显示文摘 | Robert D. Brook Sanjay Rajagopalan C. Arden Pope Jeffrey R. Brook Aruni Bhatnagar Ana V. Diez-Roux Fernando Holguin Yuling Hong Russell V. Luepker Murray A. Mittleman Annette Peters David Siscovick Sidney C. Smith Laurie Whitsel Joel D. Kaufman | 2010 | Circulation2010，，21： | 4 |
| 5 | Blackfin嵌入式媒体处理器的体系结构显示文摘引言
针对高级媒体处理要求高速信号处理和控制功能并举的应用需求,美国模拟器件公司(简称ADl)开发出了兼备上述功能的单芯片Blackfin系列媒体处理器,主要用于对多媒体应用中很普遍的实时数据流和通常由MCU操纵的控制任务进行处理.Blackfin处理器通过把信号处理模块[例如双MAC和视频运算器(ALU)]和典型的MCU功能(例如操作模式和内存管理单元)结合起来,提供了一种设计嵌入式多媒体系统的集成方法.本文主要介绍Blackfin处理器能在一个复杂的多媒体系统中完成DSP和MCU两种任务的体系结构和功能特点. | David Katz Russell Rivin | 2005 | 世界电子元器件2005，，3： | 3 |
| 6 | AMP-Activated Protein Kinase Induces a p53-Dependent Metabolic Checkpoint显示文摘 | Russell G. Jones David R. Plas Sara Kubek Monica Buzzai James Mu Yang Xu Morris J. Birnbaum Craig B. Thompson | 2005 | Molecular Cell2005，，3： | 3 |
| 7 | Clinical importance of the cytochromes P450显示文摘 | Daniel W Nebert David W Russell | 2002 | The Lancet . 2002 (9340)2002，，： | 2 |
| 8 | Single nucleotide polymorphisms in candidate genes are significantly associated with resistance to Haemonchus contortus infection in goats显示文摘Background: Haemonchosis is a major economic problem in goat production in humid, tropical and subtropical regions. The disease is caused by an abomasal nematode, Haemonchus contortus, which is highly pathogenic in small ruminants. The aim of this study was to identifying single-nucleotide polymorphisms(SNP) that were associated with fecal egg counts(FEC) and could be used as markers to identify resistance to H. contortus in goats.Results: Ten novel variants in the CI TA, ATP2 A3, HSPA8, STAT5 B, ESYT1, and SERPING1 genes were associated with FEC in goats with a nominal significance level of P < 0.05. Two missense mutation in the exon region of the caprine CI TA gene resulted in replacement of arginine with cysteine at position 9473550(R9473550 C) and aspartic acid with glutamic acid at position 9473870(D9473870 E). Chinese goat breeds had significantly higher FEC than Bangladeshi goat breeds within their respective genotypes. Polymorphism information content(PIC), effective al ele number(Ne), and heterozygosity(He)were greatest for the STAT5 B197A > G SNP locus in al goat breeds. Pairwise coefficients of linkage disequilibrium(D′, r2)revealed complete LD(r2= 1) between significant SNP polymorphisms in CI TA and SERPING1 and strong LD(r2= 0.93 and0.98) between polymorphisms in HSPA8 and ATP2 A3, respectively. Correlation coefficient(r) between FEC and body weight(BW) was significantly positive(r = 0.56***, P < 0.001) but that between FEC and packed cel volume(PCV) was negatively significant(r =-0.47**, P < 0.01) in the total population of goats. On the other hand, correlation coefficient(r)between BW and PCV was not significant in total population of goats. Association analysis revealed that haplotypes within ATP2 A3, HSPA8, and SERPING1 were significantly associated with FEC. Quantitative real-time PCR revealed that the relative expression of m RNA was higher(P < 0.001) for resistant, compared to susceptible, groups of goats for al candidate genes except CI TA.Conclusions: This study identified SNP markers that can potential y be used in marker-assisted selection programs to develop goat breeds that are resistant to H. contortus. | Mahmuda Bilkis Bintee Alam Abdullah Ibne Omar Md.Omar Faruque David Russell Notter Kathiravan Periasamy Md.Motahar Hussain Mondal Md.Jalal Uddin Sarder Md.Shamsuddin Jianhua Cao Xiaoyong Du Zhenyang Wu Shuhong Zhao | 2019 | Journal of Animal Science and Biotechnology2019，10，2： | 2 |
| 9 | Management of Newly Diagnosed Symptomatic Multiple Myeloma: Updated Mayo Stratification of Myeloma and Risk-Adapted Therapy (mSMART) Consensus Guidelines 2013显示文摘 | Joseph R. Mikhael David Dingli Vivek Roy Craig B. Reeder Francis K. Buadi Suzanne R. Hayman Angela Dispenzieri Rafael Fonseca Taimur Sher Robert A. Kyle Yi Lin Stephen J. Russell Shaji Kumar P. Leif Bergsagel Steven R. Zeldenrust Nelson Leung Matthew T. D | 2013 | Mayo Clinic Proceedings2013，，4： | 2 |
| 10 | Treatment of Unresectable Primary and Metastatic Liver Cancer with Yttrium-90 Microspheres (TheraSphere?): Assessment of Hepatic Arterial Embolization显示文摘 | Kent Sato Robert J. Lewandowski James T. Bui Reed Omary Russell D. Hunter Laura Kulik Mary Mulcahy David Liu Howard Chrisman Scott Resnick Albert A. Nemcek Robert Vogelzang Riad Salem | 2006 | CardioVascular and Interventional Radiology2006，，4： | 2 |
| 11 | An assessment of the efficacy and safety of eszopiclone in the treatment of transient insomnia in healthy adults显示文摘 | Russell Rosenberg Judy Caron Thomas Roth David Amato | 2004 | Sleep Medicine2004，，1： | 2 |
| 12 | Cavernous hemangioma arising from the gastro-splenic ligament: A case report显示文摘We present a rare case of a 45-year-old woman who presented with epigastric pain associated with early satiety and weight loss. Imaging revealed a large intraabdominal mass in the epigastrium. Despite intensive investigations, including ultrasound scanning, computed tomography, upper gastrointestinal endoscopy, and percutaneous biopsy, a diagnosis could not be obtained. A histological diagnosis of cavernous hemangioma arising from the gastro-splenic ligament was confirmed after laparoscopic excision and histological examination of the intra-abdominal epigastric mass. | Kin-Fah Chin Ghaith Khair Palani Sathish Babu David Russell Morgan | 2009 | World Journal of Gastroenterology2009，15，30： | 2 |
| 13 | Increasing diabetes self-management education in community settings显示文摘 | Susan L Norris Phyllis J Nichols Carl J Caspersen Russell E Glasgow Michael M Engelgau Leonard Jack Susan R Snyder Vilma G Carande-Kulis George Isham Sanford Garfield Peter Briss David McCulloch | 2002 | American Journal of Preventive Medicine2002，，4： | 2 |
| 14 | Capsule Endoscopy in Patients with Implantable Electromedical Devices is Safe显示文摘 | Lucinda A. Harris Stephanie L. Hansel Elizabeth Rajan Komandoor Srivathsan Robert Rea Michael D. Crowell David E. Fleischer Shabana F. Pasha Suryakanth R. Gurudu Russell I. Heigh Arthur D. Shiff Janice K. Post Jonathan A. Leighton Hsu Heng Yen | 2013 | Gastroenterology Research and Practice2013，，： | 2 |
| 15 | Inflammation as a Risk Factor for Atrial Fibrillation显示文摘 | Ronnier J. Aviles David O. Martin Carolyn Apperson-Hansen Penny L. Houghtaling Pentti Rautaharju Richard A. Kronmal Russell P. Tracy David R. Van Wagoner Bruce M. Psaty Michael S. Lauer Mina K. Chung | 2003 | Circulation: Journal of the American Heart Association2003，，24： | 2 |
| 16 | Particulate Matter Air Pollution and Cardiovascular Disease: An Update to the Scientific Statement From the American Heart Association显示文摘 | Robert D. Brook Sanjay Rajagopalan C. Arden Pope Jeffrey R. Brook Aruni Bhatnagar Ana V. Diez-Roux Fernando Holguin Yuling Hong Russell V. Luepker Murray A. Mittleman Annette Peters David Siscovick Sidney C. Smith Laurie Whitsel Joel D. Kaufman | 2010 | Circulation2010，，21： | 2 |
| 17 | Gastric food retention at endoscopy is associated with severity of liver cirrhosis显示文摘BACKGROUND Gastrointestinal symptoms are prevalent in patients with cirrhosis.Cirrhotic patients have a known predilection to delayed gastric emptying compared to those without cirrhosis.However,the contributing factors have not been fully elucidated.Retained gastric food on esophagogastroduodenoscopy(EGD)has been used as a surrogate marker for delayed gastric emptying with reasonably high specificity.Therefore,we hypothesize that the frequency of retained gastric food contents at EGD will be higher in a cirrhotic population compared to a control population without liver disease.Additionally,we hypothesize that increased frequency of gastric food contents will be associated with increased severity of cirrhosis.AIM To determine the relative frequency of delayed gastric emptying among cirrhotics as compared to non-cirrhotics and to identify associated factors.METHODSWe performed a retrospective case-control study of cirrhotic subjects whounderwent EGD at an academic medical center between 2000 and 2015. Threehundred sixty-four patients with confirmed cirrhosis, who underwent a total of1044 EGDs for the indication of esophageal variceal screening or surveillance,were identified. During the same period, 519 control patients without liverdisease, who underwent a total of 881 EGDs for the indication of anemia, wereidentified. The presence of retained food on EGD was used as a surrogate fordelayed gastric emptying. The relative frequency of delayed gastric emptyingamong cirrhotics was compared to non-cirrhotics. Characteristics of patients withand without retained food on EGD were compared using univariable andmultivariable logistic regression analysis to identify associated factors.RESULTSOverall, 40 (4.5%) patients had evidence of retained food on EGD. Cirrhotics weremore likely to have retained food on EGD than non-cirrhotics (9.1% vs 1.4%, P <0.001). Characteristics associated with retained food on univariable analysisincluded age less than 60 years (12.6% vs 5.2%, P = 0.015), opioid use (P = 0.004),Child-Pugh class C (24.1% Child-Pugh class C vs 6.4% Child-Pugh class A, P =0.007), and lower platelet count (P = 0.027). On multivariate logistic regressionanalysis, in addition to the presence of cirrhosis (adjusted OR = 5.83;95%CI: 2.32-14.7, P < 0.001), diabetes mellitus (types 1 and 2 combined) (OR = 2.34;95%CI:1.08-5.06, P = 0.031), opioid use (OR = 3.08;95%CI: 1.29-7.34, P = 0.011), andChild-Pugh class C (OR = 4.29;95%CI: 1.43-12.9, P = 0.01) were also associatedwith a higher likelihood of food retention on EGD.CONCLUSIONCirrhotics have a higher frequency of retained food at EGD than non-cirrhotics.Decompensated cirrhosis, defined by Child-Pugh class C, is associated with ahigher likelihood of delayed gastric emptying. | David B Snell Shirley Cohen-Mekelburg Russell Weg Gaurav Ghosh Adam P Buckholz Amit Mehta Xiaoyue Ma Paul J Christos Arun B Jesudian | 2019 | World Journal of Hepatology2019，11，11： | 2 |
| 18 | One-Year Clinical Results With the Slow-Release, Polymer-Based, Paclitaxel-Eluting TAXUS Stent: The TAXUS-IV Trial显示文摘 | Gregg W. Stone Stephen G. Ellis David A. Cox James Hermiller Charles O’Shaughnessy James Tift Mann Mark Turco Ronald Caputo Patrick Bergin Joel Greenberg Jeffrey J. Popma Mary E. Russell | 2004 | Circulation: Journal of the American Heart Association2004，，16： | 2 |
| 19 | Preservation of immune function in cervical cancer patients during chemoradiation using a novel integrative approach显示文摘 | Susan K. Lutgendorf Elizabeth Mullen-Houser Daniel Russell Koen DeGeest Geraldine Jacobson Laura Hart David Bender Barrie Anderson Thomas E. Buekers Michael J. Goodheart Michael H. Antoni Anil K. Sood David M. Lubaroff | 2010 | Brain Behavior and Immunity2010，，8： | 2 |
| 20 | Retention of the capsule endoscope: a single-center experience of 1000 capsule endoscopy procedures显示文摘 | Feng Li Suryakanth R. Gurudu Giovanni De Petris Virender K. Sharma Arthur D. Shiff Russell I. Heigh David E. Fleischer Janice Post Paula Erickson Jonathan A. Leighton | 2008 | Gastrointestinal Endoscopy2008，，1： | 2 |
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