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1Current status of high on-treatment platelet reactivity in patients with coronary or peripheral arterial disease:Mechanisms,evaluation and clinical implications显示文摘Antiplatelet therapy with aspirin or clopidogrel or both is the standard care for patients with proven coronary or peripheral arterial disease,especially those undergoing endovascular revascularization procedures. However,despite the administration of the antiplatelet regiments,some patients still experience recurrent cardiovascular ischemic events. So far,it is well documented by several studies that in vitro response of platelets may be extremely variable. Poor antiplatelet effect of clopidogrel or high on-treatment platelet reactivity(HTPR) is under investigation by numerous recent studies. This review article focuses on methods used for the ex vivo evaluation of HTPR,as well as on the possible underlying mechanisms and the clinical consequences of this entity. Alternative therapeutic options and future directions are also addressed.Stavros Spiliopoulos Georgios Pastromas 2015World Journal of Cardiology2015,7,12:13
2含黄芩苷的注射剂的不良反应的研究概况显示文摘随着对黄芩苷相关研究的不断发展,含黄芩苷的注射剂因疗效显著而在临床广泛使用,其不良反应也日益受到人们的重视。文章介绍了含黄芩苷的注射剂的不良反应、原因及应对策略,以期为指导临床合理性用药提供参考。杨辉 乔海灵 2015健康之路2015,0,11:1
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