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| 1 | Radioembolization for the treatment of unresectable hepatocellular carcinoma:A clinical review显示文摘Hepatocellular carcinoma(HCC)is the sixth most common cancer in the world.The majority of patients with HCC present with unresectable disease.These patients have historically had limited treatment options secondary to HCC demonstrating chemoresistance to the currently available systemic therapies.Additionally, normal liver parenchyma has shown intolerance to tumoricidal radiation doses,limiting the use of external beam radiation.Because of these limitations,novel percutaneous liver-directed therapies have emerged. The targeted infusion of radioactive microspheres (radioembolization)represents one such therapy. Radioembolization is a minimally invasive transcatheter therapy through which radioactive microspheres are infused into the hepatic arteries that supply tumor. Once infused,these microspheres traverse the hepatic vascular plexus and selectively implant within the tumor arterioles.Embedded within the arterioles, the 90Y impregnated microspheres emit high energy and low penetrating radiation doses selectively to the tumor.Radioembolization has recently shown promise for the treatment of patients with unresectable HCC. The objective of this review article is to highlight twocurrently available radioembolic devices(90Y,188Rh)and provide the reader with a recent review of the literature. | Saad M Ibrahim Robert J Lewandowski Kent T Sato Vanessa L Gates Laura Kulik Mary F Mulcahy Robert K Ryu Reed A Omary Riad Salem | 2008 | World Journal of Gastroenterology2008，14，11： | 14 |
| 2 | Diffusion-weighted magnetic resonance imaging to predict response of hepatocellular carcinoma to chemoembolization显示文摘AIM: To investigate whether intra-procedural diffusion- weighted magnetic resonance imaging can predict response of hepatocellular carcinoma (HCC) during trans- catheter arterial chemoembolization (TACE). METHODS: Sixteen patients (15 male), aged 59 ±11 years (range: 42-81 years) underwent a total of 21 separate treatments for unresectable HCC in a hybrid magnetic resonance/interventional radiology suite. Ana- tomical imaging and diffusion-weighted imaging (b = 0, 500 s/mm2) were performed on a 1.5-T unit. Tumor enhancement and apparent diffusion coefficient (ADC, mm2/s) values were assessed immediately before and at 1 and 3 mo after TACE. We calculated the percent change (PC) in ADC values at all time points. We compared follow-up ADC values to baseline values using a paired t test (α = 0.05). RESULTS: The intra-procedural sensitivity, specificity, and positive and negative predictive values (%) for detecting a complete or partial 1-mo tumor response using ADC PC thresholds of ±5%, ±10%, and ±15% were 77, 67, 91, and 40; 54, 67, 88, and 25; and 46, 100, 100, and 30, respectively. There was no clear predictive value for the 3-mo follow-up. Compared to baseline, the immediate post-procedure and 1-mo mean ADC values both increased; the latter obtaining statistical significance (1.48 ± 0.29 mm2/s vs 1.65 ± 0.35 × 10-3 mm2/s, P < 0.014). CONCLUSION: Intra-procedural ADC changes of > 15% predicted 1-mo anatomical HCC response with the greatest accuracy, and can provide valuable feedback at the time of TACE. | Johnathan C Chung Neel K Naik Robert J Lewandowski Mary F Mulcahy Laura M Kulik Kent T Sato Robert K Ryu Riad Salem Andrew C Larson Reed A Omary | 2010 | World Journal of Gastroenterology2010，16，25： | 13 |
| 3 | 铝合金材料AA-6061-T6和AA-6061-OA的动态拉伸力学性能(英文)显示文摘铝合金材料蜂窝夹层板结构具有在较低体重情况下的高硬度和高抗冲击性能力。近年来许多关于其在低应变率下冲击能量吸收性质的文献纷纷涌现,但是对于其在高应变率下的能量吸收力学性能的研究却非常贫乏。为了更好地研究铝合金材料蜂窝夹层板结构在高应变率下的能量吸收力学性能,其结构组成材料本身的动态力学性能必须首先得到充分研究。本文介绍和总结了铝合金材料AA-6061的两种热处理成品,T6与OA,在室温(24℃)与低温( -170℃)下的动态拉伸力学性能。在本研究中,霍普金生拉伸杆被应用,拉伸应变率为103每秒。 | 唐欣 Vikas Prakash John Lewandowski | 2007 | 实验力学2007，22，3： | 7 |
| 4 | Identification and Quantification of Aerosol Polar Oxygenated Compounds Bearing Carboxylic or Hydroxyl Groups.1.Method Development显示文摘In this study,a new analytical technique was developed for the identification and quantification of multifunctional compounds containing simultaneously at least one hydroxyl or one carboxylic group,or both.This technique is based on derivatizing first the carboxylic group(s) of the multifunctional compound using an alcohol (e.g.,methanol,1-butanol) in the presence of a relatively strong Lewisacid (BF3) as a catalyst.This esterification reaction quickly and quantitatively converts carboxylic acids to their ester forms.The second step is based on silylation of the ester compounds using bis(trimethylsilyl) trifluoroacetamide (BSTFA) as the derivatizing agent.For compounds bearing ketone groups in addition to carboxylic and hydroxyl groups,a third step was used based on PFBHA derivatizationof the carbonyls.Different parameters including temperature,reaction time,and effect due to artifacts were optimized.A GC/MS in EI and in methane-CI mode was used for the analysis of these compounds.The new approach was tested on a number of multifunctional compounds.The interpretation of their EI (70 eV) and CI mass spectra shows that critical information is gained leading to unambiguous identification of unknown compounds.For example,when derivatized only with BF3-methanol,their mass spectra comprise primary ions at m/z M ·+ +1,M ·+ +29,and M ·+ - 31 for compounds bearing only carboxylic groups and M ·+ +1,M ·+ +29,M ·+ -31,and M ·+ -17 for those bearing hydroxyl andcarboxylic groups.However,when a second derivatization (BSTFA) was used,compounds bearing hydroxyl and carboxylic groups simultaneously show,in addition to the ions observed before,ions at m/z M ·+ +73,M ·+ -15,M ·+ -59,M ·+ -75,M ·+ -89,and 73.To the best of our knowledge,this technique describes systematically for the first time a method for identifying multifunctional oxygenated compounds containing simultaneously one or more hydroxyl and carboxylic acid groups. | Jaoui M. Kleindienst T.E. Lewandowski M. Edney E.O. | 2004 | 天然产物研究与开发2004，16，5： | 5 |
| 5 | 八乙墓卟啉和四苯基卟啉合钌(Ⅱ)及锇(Ⅱ)的二氧加合物的红外光谱显示文摘OEP(八乙基卟啉阴离子)和TPP(四苯基卟啉阴离子)合钌(Ⅱ)和锇(Ⅱ)的二氧加合物由matrix分离技术得到(T=20-43K,P=10-5-10-6torr).为了确定v(O2)带的归属应用了同位素取代法16O2/18O2.IR谱说明对于钌的两种加合物(指OEP和TPP)都有两种异构体,其V(16O2)频率为:Ru(OEP)O2,1141和1103cm-1;Ru(TPP)O2,1167和1114cm-1.Os(TPP)O2只生成一种异构体,v(16O2)=1090cm-1,异构体v(16O2):[Ru(OEP)O2],1141cm-1,[Ru(TPP)O2],1167cm-1,这些加合物约在100K时分解,它们的结构指定为endon,而异构体[Ru(OEP)O2],1103cm-1,[Ru(TPP)O2],1114cm-1和[Os(TPP)O2],1090cm-1,在240—270K分解,它们的结构指定为桥联二聚体.在加合物中,将OEP换成TPP引起的钌加合物v(O2)频率的改变比铁和钴加合物更大.v(O2)相对强度的变化顺序为:Fe(Ⅱ)→Ru(Ⅱ)→Os(Ⅱ). | Lewandowski, W.(Institute of General Chemistry. warsaw Agricultural University.SGGW. 02-528 Warsaw, Rakowiecka 26/30, Poland)(Matrix isolation IR spectra were obtained during author’s stay at the Marquette University, Milwaukee, WI 53233(USA). | 1994 | 无机化学学报1994，10，1： | 4 |
| 6 | Fatigue behavior of high-entropy alloys: A review显示文摘Fatigue failures cost approximately 4% of the United States' gross domestic product(GDP). The design of highly fatigue-resistant materials is always in demand. Different from conventional strategies of alloy design, high-entropy alloys(HEAs) are defined as materials with five or more principal elements, which could be solid solutions. This locally-disordered structure is expected to lead to unique fatigue-resistant properties. In this review, the studies of the fatigue behavior of HEAs during the last five years are summarized. The four-point-bending high-cycle fatigue coupled with statistical modelling, and the fatigue-crack-growth behavior of HEAs, are reviewed. The effects of sample defects and nanotwins-deformation mechanisms on four-point-bending high-cycle fatigue of HEAs are discussed in detail. The influence of stress ratio and temperature on fatigue-crack-growth characteristics of HEAs is also discussed. HEAs could exhibit comparable or greater fatigue properties, relative to conventional materials. Finally,the possible future work regarding the fatigue behavior of HEAs is suggested. | CHEN PeiYong LEE Chanho WANG Shao-Yu SEIFI Mohsen LEWANDOWSKI John J DAHMEN Karin A JIA HaoLing XIE Xie CHEN BiLin YEH Jien-Wei TSAI Che-Wei YUAN Tao LIAW Peter K | 2018 | Science China(Technological Sciences)2018，61，2： | 3 |
| 7 | Microbial Biofilms显示文摘 | J W Costerton Z Lewandowski D E Caldwell D R Korber H M Lappin-Scott | 1995 | Annual Review of Microbiology1995，，： | 2 |
| 8 | A Variational Finite Element Model for Large-Eddy Simulations of Turbulent Flows显示文摘The authors introduce a new Large Eddy Simulation model in a channel,based on the projection on finite element spaces as filtering operation in its variational form,for a given triangulation{Th}h>0.The eddy viscosity is expressed in terms of the friction velocity in the boundary layer due to the wall,and is of a standard sub grid-model form outside the boundary layer.The mixing length scale is locally equal to the grid size.The computational domain is the channel without the linear sub-layer of the boundary layer.The no-slip boundary condition(or BC for short)is replaced by a Navier(BC)at the computational wall.Considering the steady state case,the authors show that the variational finite element model they have introduced,has a solution(vh,ph)h>0that converges to a solution of the steady state Navier-Stokes equation with Navier BC. | Toma's Chac'on REBOLLO Roger LEWANDOWSKI | 2013 | Chinese Annals of Mathematics,Series B2013，34，5： | 2 |
| 9 | Increased Quality of Life Among Hepatocellular Carcinoma Patients Treated with Radioembolization, Compared with Chemoembolization显示文摘 | Riad Salem Margaret Gilbertsen Zeeshan Butt Khairuddin Memon Michael Vouche Ryan Hickey Talia Baker Michael M. Abecassis Rohi Atassi Ahsun Riaz David Cella James L. Burns Daniel Ganger Al B. Benson Mary F. Mulcahy Laura Kulik Robert Lewandowski | 2013 | Clinical Gastroenterology and Hepatology2013，，： | 2 |
| 10 | 轮铲式挖掘机新一代驾驶室隔震系统的优化显示文摘提出新一代驾驶室计算机辅助设计的一些观点,重点关注驾驶室隔振系统的原始设计方案,它由挖掘悬臂连同驾驶室悬臂组成.用有限元法对驾驶室动态特性进行了分析,在虚拟模型数值分析的基础上形成一个方案,随后建立一个带有隔振系统的驾驶室原型样模,实体振动测量提供了非常令人满意的结果. | Eugeniusz Rusi■ski Tadeusz Lewandowski Wiktor S■omski 吕新生 | 2005 | 工程设计学报2005，12，3： | 2 |
| 11 | Treatment of Unresectable Primary and Metastatic Liver Cancer with Yttrium-90 Microspheres (TheraSphere?): Assessment of Hepatic Arterial Embolization显示文摘 | Kent Sato Robert J. Lewandowski James T. Bui Reed Omary Russell D. Hunter Laura Kulik Mary Mulcahy David Liu Howard Chrisman Scott Resnick Albert A. Nemcek Robert Vogelzang Riad Salem | 2006 | CardioVascular and Interventional Radiology2006，，4： | 2 |
| 12 | Delayed harvest of miscanthus—influences on biomass quantity and quality and environmental impacts of energy production显示文摘 | I Lewandowski A Heinz | 2002 | European Journal of Agronomy2002，，1： | 2 |
| 13 | Six-Degree-of-Freedom Digital Simulations for Missile Guidance and Control显示文摘 | Yongjie Xu Zhijun Wang Benbing Gao Roman Lewandowski | 2015 | Mathematical Problems in Engineering2015，，： | 2 |
| 14 | The development and current status of perennial rhizomatous grasses as energy crops in the US and Europe显示文摘 | Iris Lewandowski Jonathan M.O. Scurlock Eva Lindvall Myrsini Christou | 2003 | Biomass and Bioenergy2003，，4： | 2 |
| 15 | Radiation Lobectomy: time-dependent analysis of future liver remnant volume in unresectable liver cancer as a bridge to resection显示文摘 | Michael Vouche Robert J. Lewandowski Rohi Atassi Khairuddin Memon Vanessa L. Gates Robert K. Ryu Ron C. Gaba Mary F. Mulcahy Talia Baker Kent Sato Ryan Hickey Daniel Ganger Ahsun Riaz Jonathan Fryer Juan Carlos Caicedo Michael Abecassis Laura Kulik Riad S | 2013 | Journal of Hepatology2013，，： | 2 |
| 16 | Fibrosis, Portal Hypertension, and Hepatic Volume Changes Induced by Intra-arterial Radiotherapy with 90 Yttrium Microspheres显示文摘 | T. F. Jakobs S. Saleem B. Atassi E. Reda R. J. Lewandowski V. Yaghmai F. Miller R. K. Ryu S. Ibrahim K. T. Sato L. M. Kulik M. F. Mulcahy R. Omary R. Murthy M. F. Reiser R. Salem | 2008 | Digestive Diseases and Sciences2008，，9： | 2 |
| 17 | Combination of Morphologic Criteria and α-Fetoprotein in Selection of Patients With Hepatocellular Carcinoma for Liver Transplantation Minimizes the Problem of Posttransplant Tumor Recurrence显示文摘 | Micha? Gr?t Oskar Kornasiewicz Zbigniew Lewandowski Wac?aw Ho?ówko Karolina Gr?t Konrad Kobryń Waldemar Patkowski Krzysztof Zieniewicz Marek Krawczyk | 2014 | World Journal of Surgery2014，，10： | 2 |
| 18 | Water use efficiency and biomass partitioning of three different miseanthus genotypes with limited and unlimited water supply 显示文摘 | Clifton-brown J C Lewandowski I | 2000 | Annals of Botany2000，86，1： | 1 |
| 19 | Three-dimensional biofilm structure quantification显示文摘 | BEYENAL H DONOVAN C LEWANDOWSKI Z | 2004 | J Microbiol Methods2004，59，3： | 1 |
| 20 | Creation of an additional glycwsylation site as a mechanism for type I antithrombin deficiency显示文摘 | FITCHES AC LEWANDOWSKI K OLDS RJ | 2001 | Thromb Haemost2001，86，4： | 1 |
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