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| 1 | s Early-onset in Major Depression a Predictor of Specific Clinical Features with More Impaired Social Function?显示文摘Background: Early-onset major depressive disorder (MDD) (EOD) is often particularly malignant due to its special clinical features, accompanying impaired social function, protracted recovery time, and frequent recurrence. This study aimed to observe the effects of age onset on clinical characteristics and social function in MDD patients in Asia. Methods: In total, 547 out-patients aged 18-5 years who were from 13 study sites in five Asian countries were included. These patients had MDD diagnose according to the Diagnostic and Statistical Manual of Mental Disorders, 4^th Edition criteria. Clinical features and social function were assessed using Symptom Checklist-90-revised (SCL-90-R) and Sheehan Disability Scale (SDS). Quality of life was assessed by a 36-item Short-form Health Survey (SF-36). Analyses were performed using a continuous or dichotomous (cut-off: 30 years) age-of-onset indicator. Results: Early-onset MDD (EOD, 〈30 years) was associated with longer illness (P - 0.003), unmarried status (P 〈 0.001), higher neuroticism (P 〈 0.002) based on the SCL-90-R, and more limited social function and mental health (P = 0.006, P = 0.007) based on the SF-36 and SDS. The impairment of social function and clinical severity were more prominent at in-patients with younger onset ages. Special clinical features and more impaired social function and quality of life were associated with EOD, as in western studies. Conclusions: EOD often follows higher levels of neuroticism. Age of onset of MDD may be a predictor of clinical features and impaired social function, allowing earlier diagnosis and treatment. | Yan-Hong Liu Lin Chen Yun-Ai Su Yi-Ru Fang Manit Srisurapanont Jin Pyo Hong Ahmad Hatim Hong Choon Chua Dianne Bautista Tian-Mei Si | 2015 | Chinese Medical Journal2015，，6： | 5 |
| 2 | Clinical Performance of an Automated Stool DNA Assay for Detection of Colorectal Neoplasia显示文摘 | Graham P. Lidgard Michael J. Domanico Janelle J. Bruinsma James Light Zubin D. Gagrat Rebecca L. Oldham-Haltom Keith D. Fourrier Hatim Allawi Tracy C. Yab Julie A. Simonson Mary Devens Russell I. Heigh David A. Ahlquist Barry M. Berger | 2013 | Clinical Gastroenterology and Hepatology2013，，： | 5 |
| 3 | The correlation between keratoconus and eye rubbing: a review显示文摘Keratoconus is a non-inflammatory disorder which is gradual in development;corneal thinning and ectatic protrusion characterizes it. Keratoconus prevalence varies between different regions depending on several factors that affecting its prevalence. There are risk factors for developing keratoconus such as demographic and environmental factors. It was suggested that eye rubbing was associated with the development of keratoconus. The main aim of this review was to summarize the literature data about keratoconus and to identify the role of eyerubbing in the aetiology of the disease. A number of 24 articles was reviewed through the Pub Med, Google Scholar and Research Gates. There are many keywords used such as keratoconus, aetiology of keratoconus, eye rubbing, keratoconus prevalence, keratoconus and eye rubbing correlation. We concluded that eye rubbing causes the thinning of keratocyte, and the degree of effect of eye rubbing depends on the period and force of performing eye rubbing. It is recommended to avoid eye rubbing to prevent keratoconus, this can be achieved by avoiding itching and treating dryness of the eye and avoiding wearing eye lenses. | Hatim Najmi Yara Mobarki Khalid Mania Bashaer Altowairqi Mohammed Basehi Mohammed Salih Mahfouz Mona Elmahdy | 2019 | International Journal of Ophthalmology(English edition)2019，12，11： | 4 |
| 4 | Diagnostic accuracy of quantitative EUS elastography for discriminating malignant from benign solid pancreatic masses: a prospective, single-center study显示文摘 | Muhammad F. Dawwas Hatim Taha John S. Leeds Manu K. Nayar Kofi W. Oppong | 2012 | Gastrointestinal Endoscopy2012，，5： | 3 |
| 5 | Mortality and rebleeding following variceal haemorrhage in liver cirrhosis and periportal fibrosis显示文摘AIM To investigate mortality and rebleeding rate and identify associated risk factors at 6 wk and 5 d following acute variceal haemorrhage in patients with liver cirrhosis and schistosomal periportal fibrosis.METHODS This is a prospective study conducted during the period from March to December 2014. Patients with portal hypertension presenting with acute variceal haemorrhage secondary to either liver cirrhosis(group A) or schistosomal periportal fibroses(group B) presenting within 24 h of the onset of the bleeding were enrolled in the study and followed for a period of 6 wk. Analysis of data was done by Microsoft Excel and comparison between groups was done by Statistical Package of Social Sciences version 20 to calculate means and find the levels of statistical differences and define the mortality rates, the P value of < 0.05 was considered to be significant. RESULTS A total of 94 patients were enrolled in the study. Thirtytwo patients(34%) had liver cirrhosis(group A) and62(66%) patients had periportal fibrosis(group B).Mortality: The 6-wk and 5-d mortality were 53% and16% respectively in group A compared to 10% and 0%in group B(P value < 0.000 and < 0.004). In group A;a Child-Turcotte-Pugh class C and rebleeding within 5 d were significantly associated with 5-d mortality(P value< 0.029 and < 0.049 respectively) and Child- TurcottePugh class C was also a significant risk factor for 6-wk mortality(P value < 0.018). In group B; mortality was significantly associated with rebleeding within the 6-wk follow-up period and requirement for blood transfusion on admission(P value < 0.005 and < 0.049). Rebleeding:The 6-wk and 5-d rebleeding rate in group A were 56%and 25% respectively compared to 32% and 3% in group B(P value < 0.015 and < 0.002). Clinical presentation with encephalopathy was a significant risk factor for 5 d rebleeding in group A(P value < 0.005) while grade Ⅲperiportal fibrosis and requirement for blood transfusion on admission were significant risk factors for 6-wk rebleeding in group B(P value < 0.004 and < 0.02).CONCLUSION The 6-wk and 5-d mortality and rebleeding rate were significantly higher in patients with liver cirrhosis compared to patients with schistosomal periportal fibrosis. | Sara Elfadil Abbas Mohammed Abdelmunem Eltayeb Abdo Hatim Mohamed Yousif Mudawi | 2016 | World Journal of Hepatology2016，8，31： | 3 |
| 6 | Regenerative medicine based applications to combat stress urinary incontinence显示文摘Stress urinary incontinence(SUI), as an isolated symptom, is not a life threatening condition. However, the fear of unexpected urine leakage contributes to a significant decline in quality of life parameters for afflicted patients. Compared to other forms of incontinence, SUI cannot be easily treated with pharmacotherapy since it is inherently an anatomic problem. Treatment options include the use of bio-injectable materials to enhance closing pressures, and the placement of slings to bolster fascial support to the urethra. However, histologic findings of degeneration in the incontinent urethral sphincter invite the use of tissues engineering strategies to regenerate structures that aid in promoting continence. In this review, we will assess the role of stem cells in restoring multiple anatomic and physiological aspects of the sphincter. In particular, mesenchymal stem cells and CD34+cells have shown great promise to differentiate into muscular and vascular components,respectively. Evidence supporting the use of cytokines and growth factors such as hypoxia-inducible factor1-alpha, vascular endothelial growth factor, basic fi-broblast growth factor, hepatocyte growth factor and insulin-like growth factor further enhance the viability and direction of differentiation. Bridging the benefits of stem cells and growth factors involves the use of synthetic scaffolds like poly(1,8-octanediol-co-citrate)(POC) thin films. POC scaffolds are synthetic, elastomeric polymers that serve as substrates for cell growth,and upon degradation, release growth factors to the microenvironment in a controlled, predictable fashion.The combination of cellular, cytokine and scaffold elements aims to address the pathologic deficits to urinary incontinence, with a goal to improve patient symptoms and overall quality of life. | Hatim Thaker Arun K Sharma | 2013 | World Journal of Stem Cells2013，5，4： | 3 |
| 7 | A multifunctional Pd/alumina hollow fibre membrane reactor for propane dehydrogenation显示文摘 | Ejiro Gbenedio Zhentao Wu Irfan Hatim Benjamin F.K. Kingsbury K. Li | 2010 | Catalysis Today2010，，3： | 1 |
| 8 | Effects of Various Adjuvants (Lactic Acid, Glycerol, and Chitosan) on the Injectability of a Calcium Phosphate Cement 显示文摘 | Hatim Z Freche M | 1999 | Bone1999，25，2： | 1 |
| 9 | Effects of various adjuvants (lactic acid,glycerol,and chitosan) on the injectability of a calcium phosphate cement显示文摘 | Leroux L Hatim Z Freche M | 1999 | Bone1999，25，2： | 1 |
| 10 | Development of a catalytic hollow fiber membrane micro-reactor for high purity H2 production显示文摘 | Rahman M A Garcia-Garcia F R Hatim M D I | 2011 | Journal of Membrane Science2011，368，： | 1 |
| 11 | Amblyopia screening for first and second-grade children in Jordan显示文摘AIM:To share the results of a national screening program for amblyopia in school children in the north of Jordan.METHODS:This is a prospective national screening study for amblyopia.The program rolls first and second-grade children(6 to 7 years old) in the north of Jordan.The eye examination included:best-corrected visual acuity,cover-uncover test,and cycloplegic retinoscopy.Monocular visual acuity was tested using an ETDRS visual acuity chart without correction.Moreover,children were tested with full cycloplegic refraction when the test criteria were met.Unilateral amblyopia was defined as a best-corrected visual acuity difference of 2 or more lines.In comparison,bilateral amblyopia was defined as a best-corrected visual acuity of 20/40 or worse in the best eye.RESULTS:The prevalence of amblyopia for the total sample tested(n=17 203) was 2.78%(n=479).The most common cause of amblyopia was hypermetropia(64.45%),followed by previous ocular surgeries(15.1%),myopia(10.43%),strabismus(9.39%),and congenital cataract(0.63%).CONCLUSION:This is the first and only study,identifing modifiable risk factors in Jordanian children with amblyopia.In their first couple of years of elementary education,many Jordanian children are affected by amblyopia and pass unnoticed.A more governmental effort is needed into screening programs to improve vision in the Jordanian population. | Khalil M.Al-Salem Mohammad S.Saleem Ismat Ereifej Hamzeh M.Alrawashdeh Rayed Falah Hussein Obeidat Asma Ali Abdlmohdi Raeda Zaki Al-Momani Layal Mohammed Hammad Omar Ahmad al-Habahbeh Yaqeen M.Assassfeh Laith Ramzi Najib Al-Qsous Ashraf Hatim Adeeb Nasraween Tariq A.Al Maaitah Deya'-Aldin Muneer Hasan Aqeel Ibtehal Eyadeh Awad Alabdulrazzg Abdullah Mahmoud Mohammad Murad Amany Jehad Faleh AL-Zurqan Enas Jamal Mohammad Jaradat Slsabela Emad Suliman Aldhoon Ala'a Majed Dmour Ahmad Talal Asassfeh Jeries Ayman Halaseh Abdel Aziz Ammar Daoud Waha Ayman Alkasasbeh Kholoud GH.Matar | 2022 | International Journal of Ophthalmology(English edition)2022，15，2： | 1 |
| 12 | The Translation of Style: Linguistic markedness and textual evaluativeness 显示文摘 | Hatim Basil | 2004 | Journal of Applied Linguistics2004，，3： | 1 |
| 13 | Experimental validation of a kinetic multi-component mechanism in a wide HCCI engine operatingrange for mixtures of n-heptane, iso-octane andtoluene : Influence of EGR parameters 显示文摘 | Hatim M | 2008 | Energy Con-version and Management2008，49，11： | 1 |
| 14 | Menstrual Disorders in Adolescent Females: Current Concepts显示文摘 | Donald E. Greydanus Hatim A. Omar Artemis K. Tsitsika Dilip R. Patel | 2009 | Disease-a-Month2009，，2： | 1 |
| 15 | CD8 T cell recognition of endogenously expressed Epstein-Barr virus nuclear antigen 1 显示文摘 | Steven P Lee Jill M Brooks Hatim Al-Jarrah | 2004 | J Exp Med2004，199，10： | 1 |
| 16 | Effects of various adjuvants (Iactic acid, glycerol, and chitosan) on the injectability of a calcium phosphate cement显示文摘 | Leroux L Hatim Z Freche M | 1999 | Bone1999，25，2： | 1 |
| 17 | Effects of various adjuvants (lactic acid, glycerol, and chitosan) on the in- jectability of a calcium phosphate cement显示文摘 | Leroux L Hatim Z Freche M | 1999 | Bone1999，25，： | 1 |
| 18 | Effects of various adjuvants on the injectability of a calcium phosphate cement显示文摘 | Leroux L Hatim Z Freche M | 1999 | Bone1999，25，2： | 1 |
| 19 | Effects of different doses of dexmedetomidine on anaesthetic in- duction with alfaxalone- a clinical trial显示文摘 | RUI PINELAS HATIM IK ALIBHAI ALESSANDRA MATHIS | 2014 | Vet Anaesth Analg2014，41，4： | 1 |
| 20 | Effects of various adjuvants (lactic acid,glycerol,and chitosan) on the injectability of a calcium phosphate cement显示文摘 | LEROUX L HATIM Z FRECHE M | 1999 | Bone1999，25，2： | 1 |
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