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| 1 | MicroRNAs and prostate cancer显示文摘MicroRNAs (miRNAs ) 是否定地调整基因表示由的小、非编码的、搁浅单人赛的 RNA 的一个类对在 post-transcriptional 水平的目标 mRNAs 的 3 untranslated 区域(UTR ) 主要有约束力。最近的研究证明了 miRNAs 的异常表情仔细包括前列腺癌症(PCa ) 与各种各样的癌症的发展,侵略,转移和预后被联系。位于 miRNAs 的异常表示下面的建议分子的机制源于基因变化, epigenetic 修正和 Dicer 丰富的改变。尽管多达 50 miRNAs 被报导了显著地在人的 PCa 被表示,仅仅他们的一个小数字试验性地被显示做贡献到 PCa 的致病。这评论的目的是描述几已知的 miRNAs 的机制,在 oncogenic miRNAs 的改变的表示的关联上总结最近的研究(例如 miR-221/-222 , miR-21 ,和 miR-125b )并且肿瘤 suppressor miRNAs (例如 miR-101 , miR-126 *, miR-146a , miR-330 , miR-34 簇,并且 miR-200 家庭)为 PCa 。另外,他们在 PCa 的潜在的临床的应用和前景例如 biomarkers 和临床的治疗,简短也被讨论。 | Yingxin Pang Charles Y.F. Young Huiqing Yuan | 2010 | Acta Biochimica et Biophysica Sinica2010，42，6： | 15 |
| 2 | A Review of Botulism in China显示文摘The epidemiological characteristics and etiology of botulisin in China, as well as the distribution of different types of Clustridium bolulinum in China; are described.Through 1989, 15 provinces and autonomous regions reported the occurrence of botulism.There were 2861 cases involved in 745 outbreaks.Among the cases 421 died, with a case fatality of 14.7%.The main epidemiological characteristics of botulism in China are: (i) the major foods causing botulism are homemade fermented bean products which accounted for 62.6% of the cases; (ii) the incubation period is longer (3 h-54 days) than that described in the western literature (mostly 2-7 days); (iii) the peak occurrence is from February to May; (iv) the progression of symptoms and signs is slower than that of western cases.All types of C.bolulinum.with the exception of type G, have been found in China.The distribution of various types of C.botnlinum is significantly different between southern and northern China; this is related to the latitude and is correlated with the prevalence of this disease.Most of the botulism outbreaks occurred above 30° north latitude in northern China and outbreaks rarely occurred below 30° north latitude.Nationwide surveys showed that the average detection rate of C bolulinum spores in soil and foods in the northern parts of China was 14.8%.while it was only 2.5% in the south.C.bolulinum types A, B, E.and F, which are involved in human botulism, were frequently found in the North, while types C and D, which are involved only in animal intoxication, were found more frequently in the south. 1990 Academic Press.Inc. | GAO Q.Y. HUANG Y.F. WU J.G. LIU H.D. XIA H.Q | 1990 | Biomedical and Environmental Sciences1990，3，3： | 8 |
| 3 | Surface Characterization and Cell Response of Binary Ti-Ag Alloys with CP Ti as Material Control显示文摘In this study, the surface passive films, dissolution behavior and biocompatibility of Ti-Ag alloys (with 5%, 10% and 20% Ag) were evaluated by X-ray diffraction (XRD) tests, electrochemical corrosion tests, X-ray photoelectron spectroscopy (XPS) tests, dissolution tests and in-vitro cytotoxicity tests. The surface films on the Ti-20Ag alloy are rich in Ti and much deficient in Ag with respect to alloy composition, as identified by XPS. Compared to CP Ti, Ti-5Ag and Ti-20Ag alloys show larger impedances and lower capacitances, which can be associated with an increase of the passive layer thickness. Moreover, all Ti-Ag alloys exhibit negligible or low metal release in the test solutions. The in-vitro cytotoxicity results show Ti-Ag alloys seem to be as cytocompatible as CP Ti. From the viewpoint of surface passive film and cytotoxicity, Ti-5Ag and Ti-20Ag are considered to be more suitable for dental applications. | B.B. Zhang K.J. Qiu B.L. Wang L. Li Y.F. Zheng | 2012 | Journal of Materials Science & Technology2012，28，9： | 8 |
| 4 | Regional ozone pollution and observation-based approach for analyzing ozone–precursor relationship during the PRIDE-PRD2004 campaign显示文摘 | Y.H. Zhang H. Su L.J. Zhong Y.F. Cheng L.M. Zeng X.S. Wang Y.R. Xiang J.L. Wang D.F. Gao M. Shao S.J. Fan S.C. Liu | 2008 | Atmospheric Environment2008，，25： | 5 |
| 5 | Diameter-dependent in vitro performance of biodegradable pure zinc wires for suture application显示文摘In this study, biodegradable pure zinc wires with 3.0 mm and 0.3 mm in diameter were prepared via hot-extrusion and subsequent cold-drawing process respectively. The microstructure, mechanical performance, corrosion behavior, in vitro cytocompatibility and antibacterial effect were comparatively studied.After cold-drawing, the mechanical property, especially the elongation of the ф0.3 mm pure Zn wire was improved significantly compared with the ф3.0 mm pure Zn wire. The in vitro corrosion study including immersion and electrochemical test showed acceptable corrosion resistance of these two materials in Hank's solution. The in vitro Human Umbilical Vein Endothelial Cells(HUVECs) viability assay showed obviously different results, in which the ф0.3 mm pure Zn wire demonstrated favorable cytocompatibility, while the ф3.0 mm wire exhibited severe cytotoxic effect with 100% extract concentration. Both of them exhibited partly antibacterial effect on S. aureus. These results demonstrated the feasibility of the prepared 0.3 mm pure Zn wire as the potential suture material with good absorbability. | H. Guo R.H. Cao Y.F. Zheng J. Bai F. Xue C.L. Chu | 2019 | Journal of Materials Science & Technology2019，35，8： | 5 |
| 6 | Development of Hong Kong Liver Cancer Staging System with Treatment Stratification for Patients with Hepatocellular Carcinoma显示文摘 | Thomas Yau Vikki Y.F. Tang Tzy-Jyun Yao Sheung-Tat Fan Chung-Mau Lo Ronnie T.P. Poon | 2014 | Gastroenterology2014，，： | 5 |
| 7 | MULTI-PEAK MATCH INTENSITY RATIO METHOD OF QUANTI-TATIVE X-RAY DIFFRACTION PHASE ANALYSIS显示文摘A new method for quantitative phase analysis is proposed by using X-ray diffraction multi-peak match intensity ratio. This method can obtain the multi-peak match intensity ratio among each phase in the mixture sample by using all diffraction peak data in the mixture sample X-ray diffraction spectrum and combining the relative intensity distribution data of each phase standard peak in JCPDS card to carry on the least square method regression analysis. It is benefit to improve the precision of quantitative phase analysis that the given single line ratio which is usually adopted is taken the place of the multi-peak match intensity ratio and is used in X-ray diffraction quantitative phase analysis of the mixture sample. By analyzing four-group mixture sample, adopting multi-peak match intensity ratio and X-ray diffraction quantitative phase analysis principle of combining the adiabatic and matrix flushing method, it is tested that the experimental results are identical with theory. | G. Chu, Y.F. Cong and H.J. YouResearch Center of Analysis and Test, Liaoning University of Petroleum & Chemical Technology, Fushun 113001, China | 2003 | Acta Metallurgica Sinica(English Letters)2003，16，6： | 5 |
| 8 | STUDY ON STRUCTURES OF Al-CuAl_2 EUTECTIC SOLIDIFIED UNDER ELECTROMAGNETIC STIRRING显示文摘An investigation on electromagnetically-stirred solidification of Al-CuAl2 eutectic system is presented in this paper. With electromagnetic stirring in solidification, structural transition from lamellar to rod-like eutectic has been found in the as-cast structures, and provided strong stirring is applied, proeutectic growth of α-Al phase is enhanced. Moreover, the interphase spacing of eutectic is clearly increased with melt flow intensified. Numerical computation of flow field is also presented, and the effect of stirring on structural formation is discussed. | W.Q. Zhang Q.M. Liu Y.F. Zhu Y.S. Yang and Z.Q. Hu(State Key Laboratory of RSA, Institute of Metal Research, Chinese Academy of Sciences, Shenyang 110015, China) | 1997 | Acta Metallurgica Sinica(English Letters)1997，10，6： | 4 |
| 9 | SIMULATION OF THE MICROSTRUCTURE DISTRIBUTION OF HYDROGEN STORAGE ALLOY AND OPTIMAL DESIGN OF CASTING MOULDS显示文摘In this paper,a simulation model for the temperature field in the solidification process and microstructure distribution is presented. Then, the result of simulation for the final microstructure distribution is compared with experiment using 10-Kg ingot of MlNi3.55Al0.3Mn0.4CO0.75 (Ml: Lanthanum-rich Mischmetal) hydrogen stor- age alloy cast in a mould, which agrees with the experiment well. Finally, in order to obtain the expected as-cast microstructure distribution of 15-Kg ingot of MlNi3.55Al0.3Mn0.4Co0.75 alloy, the size of Cu mould is optimized using the model described. The optimized mould is then made and the alloy is cast in it, the expected as-cast microstructure distribution is obtained. | Q.A. Li, H.Q. Mo, Y.Z. Huo, G. Sang, Y.F. Chen, M.G. Han, Y.G. Chen and M.J. Tu Department of Metal Materials, Sichuan University, Chengdu 610065, China | 2000 | Acta Metallurgica Sinica(English Letters)2000，13，2： | 4 |
| 10 | Mesozoic molybdenum deposits in the east Qinling–Dabie orogenic belt: Characteristics and tectonic settings显示文摘 | J.W. Mao F. Pirajno J.F. Xiang J.J. Gao H.S. Ye Y.F. Li B.J. Guo | 2011 | Ore Geology Reviews2011，，1： | 3 |
| 11 | Characterization of high-pressure die-cast hypereutectic Al-Si alloys based on microstructural distribution and fracture morphology显示文摘The fracture behavior of high-pressure die-cast hypereutectic(HPDC) Al-Si alloys was investigated using a high-resolution laboratory CT and synchrotron X-ray tomography with a particular focus on the influence of HPDC microstructure. Results showed that microstructure of the alloy was mainly comprised of primary silicon particles(PSPs), Al dendrites, Cu-rich phases and pores. Most of the coarse PSPs, Cu-rich phases and pores were located in the center of the specimen. The rapid solidification of HPDC led to a heterogeneous microstructural feature. Elemental Cu was enriched in the frontiers of solid-liquid interface, causing the formation of large size dendritic arms. The pores were formed in the interdendrites which endured high stress intensity under high applied stress. Microcracks were originated from pores and further connected Cu-rich phases causing intergranular fracture. PSPs worked as obstacles causing piling-up dislocations in the phase interface. In the regions where large size of PSPs enriched in, PSPs ruptured rather than debonded from matrix, indicating transgranular fractures of PSPs. Microcracks originated around pores and PSPs tended to converge on the main cracks to decrease the energy required for crack propagation. | X.Y. Jiao J. Wang C.F. Liu Z.P. Guo G.D. Tong S.L. Ma Y. Bi Y.F. Zhang S.M. Xiong | 2019 | Journal of Materials Science & Technology2019，35，6： | 3 |
| 12 | THE STRAIN CYCLIC CHARACTERISTICS AND RATCHETING OF U71Mn RAIL STEEL UNDER UNIAXIAL LOADING显示文摘An experimental study was carried out of the cyclic behavior of U71Mn rail steel subjected to uniaxial strain and stress. The effects of cyclic struin amplitude, mean struin,strain loading rate and their histories on the strain cyclic characteristics were studied.Under the asymmetrical stress cycling, the effects of stress amplitude, mean stress,stress loading rate and their histories on the ratcheting were analyzed. The interaction between strain cycling and stress cycling was also discussed. It is shown that either the cyclic characteristics under strain cycling or the ratcheting under asymmetrical stress cycling depends not only on the cumnt loading state, but also on the previous loading history. Some significant results are obtained. | G.Z. Kang Q. Gao, X.J.Yang and Y.F. Sun(Department of Applied Mechanics and Engineering, Southwest Jiaotong University, Chengdu 610031, China) | 2000 | Acta Metallurgica Sinica(English Letters)2000，13，3： | 3 |
| 13 | Grain refinement mechanism of multiple laser shock processing impacts on ANSI 304 stainless steel显示文摘 | J.Z. Lu K.Y. Luo Y.K. Zhang G.F. Sun Y.Y. Gu J.Z. Zhou X.D. Ren X.C. Zhang L.F. Zhang K.M. Chen C.Y. Cui Y.F. Jiang A.X. Feng L. Zhang | 2010 | Acta Materialia2010，，16： | 3 |
| 14 | RECOVERY OF CADMIUM AND NICKEL FROM SCRAP Ni-Cd BATTERIES显示文摘Several typical methods for the recovery of Ni-Cd batteries are described in detail. Based on the comparing of hydrometallurgical and pyrometallurgical processes, the latter was selected as the suitable method for recycling Ni-Cd batteries in China. | J.X. Zhu1), B. Yu2), J.H. Li1) and Y.F. Nie1) 1) Department of Environmental Engineering, Tsinghua University, Beijing 100084, China 2) Institute of Nuclear Energy Technology, Tsinghua University, Beijing 100084, China | 2001 | Acta Metallurgica Sinica(English Letters)2001，14，4： | 3 |
| 15 | Lethal-7 is down-regulated by the hepatitis B virus x protein and targets signal transducer and activator of transcription 3显示文摘 | Yu Wang Yiwei Lu Soo Ting Toh Wing-Kin Sung Patrick Tan Pierce Chow Alexander Y.F. Chung London L.P. Jooi Caroline G.L. Lee | 2010 | Journal of Hepatology2010，，1： | 3 |
| 16 | Effect of Sn addition on the microstructure and superelasticity in Ti–Nb–Mo–Sn Alloys显示文摘 | D.C. Zhang S. Yang M. Wei Y.F. Mao C.G. Tan J.G. Lin | 2012 | Journal of the Mechanical Behavior of Biomedical Materials2012，，： | 2 |
| 17 | The clinical value of serum CEA, CA19-9, and CA242 in the diagnosis and prognosis of pancreatic cancer显示文摘 | X.G. Ni X.F. Bai Y.L. Mao Y.F. Shao J.X. Wu Y. Shan C.F. Wang J. Wang Y.T. Tian Q. Liu D.K. Xu P. Zhao | 2004 | European Journal of Surgical Oncology2004，，2： | 2 |
| 18 | Effect of non-metallic inclusions on hydrogen-induced cracking of API5L X100 steel显示文摘 | T.Y. Jin Z.Y. Liu Y.F. Cheng | 2010 | International Journal of Hydrogen Energy2010，，15： | 2 |
| 19 | MICROSTRUCTURE AND MACROSEGREGATION OF Al-7%Si ALLOY SOLIDIFIED UNDER COMPLEX EFFECTS OF ELECTROMAGNETIC AND CENTRIFUGAL FORCES显示文摘Macrosegregations and microstructures of Al-7%Si alloy solidified under complex of fects of magnetic field and centrifugal forces are studied by means of a set of selfdesigned electromagnetic centrifugal casting (EMCC) device. It is shown that electromagnetic field (EMF) has an important effect on the macrosegregation of centrifugal casting specimen of Al-7%Si alloy in two respects: one is that there exists always a kind of convection in the liquid in front of the S/L interface caused by effect ofthe electromagnetic force; the other is that different atomic clusters of solidparticles with different physical characteristics are subjected to quite different electromagnetic (Lorentz) force. Therefore, their movements get changed. In addition, the formation process of a complex band structure consisting of primary α-Al dendrites and (α-Al+β-Si) eutectics in hypoeutectic Al-Si alloys during EMCC and the effect of EMF are discussed. | Y.F. Zhu W.Q. Zhang Y.S. Yang Q.M. Liu and Z.Q. Hu (State Key Lab. of RSA, Institute of Metal Research, Chinese Academy of Sciences, Shenyang 110015,Chilla) | 1997 | Acta Metallurgica Sinica(English Letters)1997，10，2： | 2 |
| 20 | Adipokines Linking Obesity with Colorectal Cancer Risk in Postmenopausal Women显示文摘 | Gloria Y.F. Ho Tao Wang Marc J. Gunter Howard D. Strickler Mary Cushman Robert C. Kaplan Sylvia Wassertheil-Smoller Xiaonan Xue Swapnil N. Rajpathak Rowan T. Chlebowski Mara Z. Vitolins Philipp E. Scherer Thomas E. Rohan | 2012 | Cancer Research2012，，12： | 2 |
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