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| 1 | Predictive value of C-reactive protein/albumin ratio in acute pancreatitis显示文摘BACKGROUND:Serum C-reactive protein(CRP) increases and albumin decreases in patients with inflammation and infection.However,their role in patients with acute pancreatitis is not clear.The present study was to investigate the predictive significance of the CRP/albumin ratio for the prognosis and mortality in acute pancreatitis patients.METHODS:This study was performed retrospectively with 192 acute pancreatitis patients between January 2002 and June 2015.Ranson scores,Atlanta classification and CRP/albumin ratios of the patients were calculated.RESULTS:The CRP/albumin ratio was higher in deceased patients compared to survivors.The CRP/albumin ratio was positively correlated with Ranson score and Atlanta classification in particular and with important prognostic markers such as hospitalization time,CRP and erythrocyte sedimentation rate.In addition to the CRP/albumin ratio,necrotizing pancreatitis type,moderately severe and severe Atlanta classification,and total Ranson score were independent risk factors of mortality.It was found that an increase of 1 unit in the CRP/albumin ratio resulted in an increase of 1.52 times in mortality risk.A prediction value about CRP/albumin ratio >16.28 was found to be a significant marker in predicting mortality with 92.1% sensitivity and 58.0% specificity.It was seen that Ranson and Atlanta classification were higher in patients with CRP/albumin ratio >16.28 compared with those with CRP/albumin ratio ≤16.28.Patients with CRP/albumin ratio >16.28 had a 19.3 times higher chance of death.CONCLUSION:The CRP/albumin ratio is a novel but promising,easy-to-measure,repeatable,non-invasive inflammationbased prognostic score in acute pancreatitis. | Mustafa Kaplan Ihsan Ates Muhammed Yener Akpinar Mahmut Yuksel Ufuk Baris Kuzu Sabite Kacar Orhan Coskun Ertugrul Kayacetin | 2017 | Hepatobiliary & Pancreatic Diseases International2017，16，4： | 53 |
| 2 | Increasing Incidence and Prevalence of the Inflammatory Bowel Diseases With Time, Based on Systematic Review显示文摘 | Natalie A. Molodecky Ing Shian Soon Doreen M. Rabi William A. Ghali Mollie Ferris Greg Chernoff Eric I. Benchimol Remo Panaccione Subrata Ghosh Herman W. Barkema Gilaad G. Kaplan | 2012 | Gastroenterology2012，，1： | 33 |
| 3 | 闭环式管理:从战略到运营显示文摘平衡计分卡创始人罗伯特·卡普兰和戴维·诺顿建立了一个闭环式的管理体系,将战略和运营结合起来,并为每个阶段提供了各种工具。 | 罗伯特·卡普兰(Robert S. Kaplan) 戴维·诺顿(David P. Norton) 章程(翻译) | 2008 | 商业评论2008，，2： | 32 |
| 4 | New response evaluation criteria in solid tumours: Revised RECIST guideline (version 1.1)显示文摘 | E.A. Eisenhauer P. Therasse J. Bogaerts L.H. Schwartz D. Sargent R. Ford J. Dancey S. Arbuck S. Gwyther M. Mooney L. Rubinstein L. Shankar L. Dodd R. Kaplan D. Lacombe J. Verweij | 2008 | European Journal of Cancer2008，，2： | 22 |
| 5 | A Survey of Unbalanced Flow Diagnostics and Their Application显示文摘This paper presents an extensive survey of the most commonly used tools for diagnosing unbalanced flow in the atmosphere, namely the Lagrangian Rossby number, Psi vector, divergence equation, nonlinear balance equation, generalized omega-equation, and departure from fields obtained by potential vorticity (PV) inversion. The basic thoery, assumptions as well as implementation and limitations for each of the tools are all discussed. These tools are applied to high-resolution mesoscale model data to assess the role of unbalanced dynamics in the generation of a mesoscale gravity wave event over the East Coast of the United States. Comparison of these tools in this case study shows that these various methods agree to a large extent with each other though they differ in details. | Fuqing Zhang Steven E. Koch Christopher A. Davis and Michael L. Kaplan | 2000 | Advances in Atmospheric Sciences2000，17，2： | 22 |
| 6 | Upper-gastrointestinal bleeding secondary to peptic ulcer disease:Incidence and outcomes显示文摘AIM:To evaluate the incidence,surgery,mortality,and readmission of upper gastrointestinal bleeding(UGIB)secondary to peptic ulcer disease(PUD).METHODS:Administrative databases identified all hospitalizations for UGIB secondary to PUD in Alberta,Canada from 2004 to 2010(n=7079)using the International Classification of Diseases Codes(ICD-10).A subset of the data was validated using endoscopy reports.Positive predictive value and sensitivity with 95%confidence intervals(CI)were calculated.Incidence of UGIB secondary to PUD was calculated.Logistic regression was used to evaluate surgery,in-hospital mortality,and 30-d readmission to hospital with recurrent UGIB secondary to PUD.Co-variants accounted for in our logistic regression model included:age,sex,area of residence(i.e.,urban vs rural),number of Charlson comorbidities,presence of perforated PUD,undergoing upper endoscopy,year of admission,and interventional radiological attempt at controlling bleeding.A subgroup analysis(n=6356)compared outcomes of patients with gastric ulcers to those with duodenal ulcers.Adjusted estimates are presented as odds ratios(OR)with95%CI.RESULTS:The positive predictive value and sensitivity of ICD-10 coding for UGIB secondary to PUD were85.2%(95%CI:80.2%-90.2%)and 77.1%(95%CI:69.1%-85.2%),respectively.The annual incidence between 2004 and 2010 ranged from 35.4 to 41.2 per100000.Overall risk of surgery,in-hospital mortality,and 30-d readmission to hospital for UGIB secondary to PUD were 4.3%,8.5%,and 4.7%,respectively.Interventional radiology to control bleeding was performed in 0.6%of patients and 76%of these patients avoided surgical intervention.Thirty-day readmission significantly increased from 3.1%in 2004 to 5.2%in 2010(OR=1.07;95%CI:1.01-1.14).Rural residents(OR rural vs urban:2.35;95%CI:1.83-3.01)and older individuals(OR≥65 vs<65:1.57;95%CI:1.21-2.04)were at higher odds of being readmitted to hospital.Patients with duodenal ulcers had higher odds of dying(OR=1.27;95%CI:1.05-1.53),requiring surgery(OR=1.73;95%CI:1.34-2.23),and being readmitted to hospital(OR=1.54;95%CI:1.19-1.99)when compared to gastric ulcers.CONCLUSION:UGIB secondary to PUD,particularly duodenal ulcers,was associated with significant morbidity and mortality.Early readmissions increased over time and occurred more commonly in rural areas. | Samuel Quan Alexandra Frolkis Kaylee Milne Natalie Molodecky Hong Yang Elijah Dixon Chad G Ball Robert P Myers Subrata Ghosh Robert Hilsden Sander Veldhuyzen van Zanten Gilaad G Kaplan | 2014 | World Journal of Gastroenterology2014，20，46： | 21 |
| 7 | 《国际功能、残疾和健康分类·足跟痛/足底筋膜炎:2014修订版》临床实践指南显示文摘美国物理治疗协会(APTA)骨科分会一直致力于为世界卫生组织国际功能、残疾与健康分类(ICF)所描述的肌肉骨骼障碍患者的骨科物理治疗管理制定循证实践指南。修订临床实践指南的目的是回顾最近的同行评议文献,并对非关节炎足跟痛作出建议。 | Roy D.ALTMAN Paul BEATTIE Mark CORNWALL Irene DAVIS John DEWITT James ELLIOTT James J.IRRGANG Sandra KAPLAN Stephen PAULSETH Leslie TORBURN James ZACHAZEWSKI 韩云峰 苟艳芸 李萌 林志刚 王芗斌 张洁 | 2019 | 康复学报2019，29，1： | 20 |
| 8 | Microbial profile and antibiotic sensitivity pattern in bile cultures from endoscopic retrograde cholangiography patients显示文摘AIM:To identify the frequency of bacterial growth,the most commonly grown bacteria and their antibiotic susceptibility,and risk factors for bacterial colonization in bile collected from patients with different biliary diseases.METHODS:This prospective study was conducted between April 2010 and August 2011.Patients with various biliary disorders were included.Bile was aspirated by placing a single-use,5F,standard sphincterotome catheter into the bile duct before the injection of contrast agent during endoscopic retrograde cholangiopancreaticography (ERCP).Bile specimens were transported to the microbiology laboratory in blood culture bottles within an anaerobic transport system.Bacteria were cultured and identified according to the standard protocol used in our clinical microbiology laboratory.The susceptibilities of the organisms recovered were identified using antimicrobial disks,chosen according to the initial gram stain of the positive cultures.RESULTS:Ninety-one patients (27% male,mean age 53.7 ± 17.5 years,range:17-86 years) were included in the study.The main indication for ERCP was benign biliary disease in 79 patients and malignant disease in 12 patients.The bile culture was positive for bacterial growth in 46 out of 91 (50.5%) patients.The most frequently encountered organisms were Gram-negative bacteria including Escherichia coli (28.2%),Pseudomonas (17.3%) and Stenotrophomonas maltophilia (15.2%).There were no significant differences between patients with malignant and benign disease (58% vs 49%,P = 0.474),patients with acute cholangitis and without acute cholangitis (52.9% vs 50%,P = 0.827),patients who were empirically administered antibiotics before intervention and not administered (51.4% vs 60.7%,P = 0.384),with regard to the bacteriobilia.We observed a large covering spectrum or low resistance to meropenem,amikacin and imipenem.CONCLUSION:We did not find a significant risk factor for bacteriobilia in patients with biliary obstruction.A bile sample for microbiological analysis may become a valuable diagnostic tool as it leads to more accurate selection of antibiotics for the treatment of cholangitis. | Muhsin Kaya Remzi Bestas Fatma Bacalan Ferhat Bacaksz Esma Gülsun Arslan Mehmet Ali Kaplan | 2012 | World Journal of Gastroenterology2012，18，27： | 13 |
| 9 | Enteral stents for the management of malignant colorectal obstruction显示文摘Colorectal cancer(CRC) is the 3rd most common cancer in the United States with more than 10000 new cases diagnosed annually. Approximately 20% of patients with CRC will have distant metastasis at time of diagnosis, making them poor candidates for primary surgical resection. Similarly, 8%-25% of patients with CRC will present with bowel obstruction and will require palliative therapy. Emergent surgical decompression has a high mortality and morbidity, and often leads to a colostomy which impairs the patient's quality of life. In the last decade, there has been an increasing use of colonic stents for palliative therapy to relieve malignant colonic obstruction. Colonic stents have been shown to be effective and safe to treat obstruction from CRC, and are now the therapy of choice in this scenario. In the setting of an acute bowel obstruction in patients with potentially resectable colon cancer, stents may beused to delay surgery and thus allow for decompression, adequate bowel preparation, and optimization of the patient's condition for curative surgical intervention. An overall complication rate(major and minor) of up to 25% has been associated with the procedure. Long term failure of stents may result from stent migration and tumor ingrowth. In the majority of cases, repeat stenting or surgical intervention can successfully overcome these adverse effects. | Jeremy Kaplan Anna Strongin Douglas G Adler Ali A Siddiqui | 2014 | World Journal of Gastroenterology2014，20，37： | 13 |
| 10 | 慢性阻塞性肺病显示文摘 | Alan Kaplan 李井泉 | 2005 | 中国全科医学2005，8，2： | 9 |
| 11 | Users of the world, unite! The challenges and opportunities of Social Media显示文摘 | Andreas M. Kaplan Michael Haenlein | 2009 | Business Horizons2009，，1： | 9 |
| 12 | Inflammatory bowel disease imaging:current practice andfuture directions显示文摘The purpose of this paper is to evaluate the role of imaging in inflammatory bowel disease(IBD), including detection of extraluminal complications and extraintestinal manifestations of IBD, assessment of disease activity and treatment response, and discrimination of inflammatory from fibrotic strictures. IBD is a chronic idiopathic disease affecting the gastrointestinal tract that is comprised of two separate, but related intestinal disorders; Crohn's disease and ulcerative colitis. The paper discusses, in detail the pros and cons of the different IBD imaging modalities that need to be considered in order to optimize the imaging and clinical evaluation of patients with IBD. Historically, IBD evaluation of the bowel has included imaging to assess the portions of the small bowel that are inaccessible to optical endoscopic visualization. This traditionally was performed using barium fluoroscopic techniques; however, cross-sectional imaging techniques(computed tomography and magnetic resonance imaging) are being increasingly utilized for IBD evaluation because they can simultaneously assess mural and extramural IBD manifestations. Recent advances in imaging technology, that continue to improve the ability of imaging to noninvasively follow disease activity and treatment response, are also discussed. This review article summarizes the current imaging approach in inflammatory bowel disease as well as the role of emerging imaging modalities. | Aoife Kilcoyne Jess L Kaplan Michael S Gee | 2016 | World Journal of Gastroenterology2016，22，3： | 8 |
| 13 | STAT5 programs a distinct subset of GM-CSF-producing T helper cells that is essential for autoimmune neuroinflammation显示文摘 | Wanqiang Sheng Fan Yang Yi Zhou Henry Yang Pey Yng Low David Michael Kemeny Patrick Tan Akira Moh Mark H Kaplan Yongliang Zhang Xin-Yuan Fu | 2014 | Cell Research2014，24，12： | 7 |
| 14 | 原发性甲状旁腺机能亢进症的外科治疗——九十年代进展显示文摘原发性甲状旁腺机能亢进症(PHPT)已不再是少见病。据统计,美国每500个年龄超过40岁的女性及每2000个男性中就有一个 PHPT 患者,成为门诊高钙血症病人的首要病因。作者就近年来 PHPT 外科治疗的一些新的进展进行了综述。诊断 PHPT 的典型症状包括骨痛、肾结石、腹痛和精神症状。所谓“无症状”的 PHPT 患者,仔细询问病史,多诉有程度不同的虚弱、乏力、抑郁、烦渴多尿、关节痛等非特征性症状,极少数病人可于颈部扪及肿块。实验室检查主要依据同时出现的高钙低磷血症及血甲状旁腺素(PTH)水平的升高。判断血钙浓度要同时测定血浆蛋白含量;低蛋白血症患者,血钙总量虽然在正常范围内,但由于离子钙浓度的升高。 | Kaplan EL 高祖华 | 1992 | 国外医学(外科学分册)1992，19，5： | 7 |
| 15 | 睾酮和良性前列腺增生症显示文摘由于医患双方对于男性迟发性腺功能减退症状的警觉,使得近期针对此类患者的睾酮治疗增多。但是考虑到睾酮治疗对前列腺的影响,尤其可能增加前列腺癌发病风险,促进了该方面的研究进展。出乎意料的是大量的回顾性或小样本随机研究提示睾酮治疗或可改善男性下尿路症状。虽然此改善的确切机理仍在争论中,但或许和代谢综合征密切相关。对于临床医生,这些研究的结果虽然让人期待,但是缺乏高等级证据支持。因此在诊断迟发性腺功能减退症或考虑睾酮治疗前,仍需对患者进行包括病史、体检和睾酮测量在内的全面临床检查。睾酮补充治疗可能导致尿潴留和加重下尿路症状,这些产品说明上标注的风险依然存在,应该在用药前向患者解释说明。 | Thomas R Jarvis Bilal Chughtai Steven A Kaplan | 2015 | Asian Journal of Andrology2015，17，2： | 7 |
| 16 | New response evaluation criteria in solid tumours: Revised RECIST guideline (version 1.1)显示文摘 | E.A. Eisenhauer P. Therasse J. Bogaerts L.H. Schwartz D. Sargent R. Ford J. Dancey S. Arbuck S. Gwyther M. Mooney L. Rubinstein L. Shankar L. Dodd R. Kaplan D. Lacombe J. Verweij | 2008 | European Journal of Cancer2008，，2： | 6 |
| 17 | Coronary artery bypass grafting in the octogenarians: should we intervene, or leave them be?显示文摘ObjectiveCoronary 动脉绕过 grafting (CABG ) 逐渐地在老人口正在增加。我们试图在 80 的年龄和 older.MethodsBetween 2002年1月和2011年12月在病人与长期的幸存一起调查风险因素和 CABG 的结果,在 80 的年龄的 101 个连续病人的一个总数并且更旧在我们的医院里经历了 CABG 的人,在学习被包括。病人被跟随,长期的幸存是病人的 estimated.ResultsThe 平均数年龄是 82.98 ±2.27 年。(63.4%) 64 是男性,(36.6%) 37 是女性。紧急情况外科,持续时间心肺绕过,特别护理单位(ICU ) 停留, inotropic 支持,大动脉的汽球跳动申请,红血球输送的数量和新鲜冻结的血浆输送和通风时期是的 intra 在在医院里死了的病人显著地更高。持续时间心肺绕过(CPB ) 被发现是死亡的一个独立预言者(或:1.18, 95% CI 1.01 − 1.38, P = 0.034 ) 。在里面医院死亡是 16.8% 。Kaplan-Meier 分析在一年揭示了 91.3% 的幸存比率, 82.9% 在三年并且 69.0% 在五 years.ConclusionsPatients 在 80 岁时并且更旧 CABG 过程的候选人能正在牢记他们可以有一个更长的通风时期和特别护理单位停留。这个年龄组的病态和死亡在一个可接受的范围以内被考虑。最小化 CPB 的途径,或离开泵外科的选择,可以是一个预防方法降低死亡的发生。因此, CABG 可以与令人满意的幸存比率在这个年龄组被执行。 | Anil Ozen Ertekin Utku Unal Murat Songur Sinan Sabit Kocabeyoglu Onur Hanedan Metin Yilmaz Basak Soran Turkcan Ferit Cicekcioglu Sadi Kaplan Cemal Levent Birincioglu | 2015 | Journal of Geriatric Cardiology2015，12，2： | 5 |
| 18 | The impact of extracellular and intracellular Ca2+ on ethanol-induced smooth muscle contraction显示文摘 | Naciye YAKTUBAY DONDA Mahir KAPLAN erya KAYA Ergin singIrIK | 2009 | Acta Pharmacologica Sinica2009，30，10： | 5 |
| 19 | The restorative benefits of nature: Toward an integrative framework显示文摘 | Stephen Kaplan | 1995 | Journal of Environmental Psychology1995，，3： | 4 |
| 20 | Solving Space-Time Fractional Differential Equations by Using Modified Simple Equation Method显示文摘In this article,we establish new and more general traveling wave solutions of space-time fractional Klein–Gordon equation with quadratic nonlinearity and the space-time fractional breaking soliton equations using the modified simple equation method.The proposed method is so powerful and effective to solve nonlinear space-time fractional differential equations by with modified Riemann–Liouville derivative. | Melike Kaplan Arzu Akbulut Ahmet Bekir | 2016 | Communications in Theoretical Physics2016，65，5： | 4 |
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