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| 1 | Role of endoscopy in predicting the disease course in inflammatory bowel disease显示文摘Endoscopy provides a direct evaluation of mucosal lesions in inflammatory bowel disease(IBD),permitting the description of elementary lesions,their surface extent and severity.The severity of mucosal lesions directly reflects disease activity and may help to identify an aggressive behavior of the disease.Several studies have recently pointed out the potential role of endoscopy in the prediction of IBD outcome.Indeed,severe endoscopic lesions in Crohn's disease(CD) patients,defined by deep and extensive ulcerations on at least one part of the colon,are associated with an increased risk of penetrating complication and surgery.Severe endoscopic lesions during severe attacks of ulcerative colitis(UC) are associated with an increased risk of colectomy in the short and long term.Severity of postoperative recurrence in CD may help to predict the risk of clinical relapse and need for further surgery.Achievement of mucosal healing,which can be obtained by administration of several types of drugs,is associated with a better outcome,less surgery and hospitalization.This review focuses on the assessment of endoscopic severity in CD and UC and on the impact of endoscopic severity on disease outcome.More specifically,we discuss how endoscopy can be used at different stages of IBD to predict the disease course and/or to adapt treatment strategies. | Matthieu Allez Marc Lémann | 2010 | World Journal of Gastroenterology2010，16，21： | 10 |
| 2 | Safety and Efficacy of Antigen-Specific Regulatory T-Cell Therapy for Patients With Refractory Crohn’s Disease显示文摘 | Pierre Desreumaux Arnaud Foussat Matthieu Allez Laurent Beaugerie Xavier Hébuterne Yoram Bouhnik Maria Nachury Valérie Brun Hervé Bastian Nathalie Belmonte Michel Ticchioni Agnès Duchange Patricia Morel–Mandrino Virginie Neveu Nathalie Clerget–Chossat Mig | 2012 | Gastroenterology2012，，5： | 4 |
| 3 | Hepatic complications induced by immunosuppressants and biologics in inflammatory bowel disease显示文摘The incidence of inflammatory bowel diseases(IBD)is rising worldwide.The therapeutic options for IBD are expanding,and the number of drugs with new targets will rapidly increase in coming years.A rapid step-up approach with close monitoring of intestinal inflammation is extensively used.The fear of side effects represents one the most limiting factor of their use.Despite a widespread use for years,drug induced liver injury(DILI)management remains a challenging situation with Azathioprine and Methotrexate.DILI seems less frequent with anti-tumor necrosis factor agents and new biologic therapies.The aim of this review is to report incidence,physiopathology and practical guidelines in case of DILI occurrence with the armamentarium of old and new drugs in the field of IBD. | My-Linh Tran-Minh Paula Sousa Marianne Maillet Matthieu Allez Jean-Marc Gornet | 2017 | World Journal of Hepatology2017，9，13： | 3 |
| 4 | Ciclosporin versus infliximab in patients with severe ulcerative colitis refractory to intravenous steroids: a parallel, open-label randomised controlled trial显示文摘 | David Laharie Arnaud Bourreille Julien Branche Matthieu Allez Yoram Bouhnik Jerome Filippi Frank Zerbib Guillaume Savoye Maria Nachury Jacques Moreau Jean-Charles Delchier Jacques Cosnes Elena Ricart Olivier Dewit Antonio Lopez-Sanroman Jean-Louis Dupas F | 2012 | The Lancet2012，，9857： | 2 |
| 5 | Trough levels and antibodies to infliximab may not predict response to intensification of infliximab therapy in patients with inflammatory bowel disease显示文摘 | Benjamin Pariente Guillaume Pineton de Chambrun Roman Krzysiek Marine Desroches Gauthier Louis Chiara De Cassan Clotilde Baudry Jean‐Marc Gornet Pierre Desreumaux Dominique Emilie Jean‐Frédéric Colombel Matthieu Allez | 2011 | Inflamm Bowel Dis2011，，7： | 2 |
| 6 | Early Administration of Azathioprine vs Conventional Management of Crohn’s Disease: a Randomized Controlled Trial显示文摘 | Jacques Cosnes Anne Bourrier David Laharie Stéphane Nahon Yoram Bouhnik Franck Carbonnel Matthieu Allez Jean-Louis Dupas Jean-Marie Reimund Guillaume Savoye Pauline Jouet Jacques Moreau Jean-Yves Mary Jean-Frédéric Colombel | 2013 | Gastroenterology2013，，： | 2 |
| 7 | Excess primary intestinal lymphoproliferative disorders in patients with inflammatory bowel disease显示文摘 | Harry Sokol Laurent Beaugerie Marc Maynadié David Laharie Jean‐Louis Dupas Bernard Flourié Eric Lerebours Laurent Peyrin‐Biroulet Matthieu Allez Tabassome Simon Fabrice Carrat Nicole Brousse | 2012 | Inflamm Bowel Dis2012，，11： | 1 |
| 8 | 561 Successive Treatment with Cyclosporine and Infliximab in Severe Ulcerative Colitis (UC)显示文摘 | Sarah Leblanc Matthieu Allez Philippe Seksik Bernard Flourie Harald Peeters Jean-Louis Dupas Guillaume Bouguen Laurent Peyrin Biroulet Arnaud Bourreille Olivier Dewit Yoram Bouhnik Pierre F. Michetti Stanislas Chaussade Philippe de Saussure Jean-Frederic | 2009 | Gastroenterology2009，，5： | 1 |
| 9 | Subcutaneous Ustekinumab Provides Clinical Benefit for Two-Thirds of Patients With Crohn’s Disease Refractory to Anti–Tumor Necrosis Factor Agents显示文摘 | Pauline Wils Yoram Bouhnik Pierre Michetti Bernard Flourie Hedia Brixi Anne Bourrier Matthieu Allez Bernard Duclos Jean-Charles Grimaud Anthony Buisson Aurélien Amiot Mathurin Fumery Xavier Roblin Laurent Peyrin-Biroulet Jér?me Filippi Guillaume Bouguen V | 2016 | Clinical Gastroenterology and Hepatology2016，，2： | 1 |
| 10 | Prevalence and clinical impact of endoscopic pseudomembranes in patients with inflammatory bowel disease and Clostridium difficile infection显示文摘 | Shomron Ben-Horin Maya Margalit Peter Bossuyt Jochen Maul Yami Shapira Daniela Bojic Irit Chermesh Ahmad Al-Rifai Alain Schoepfer Matteo Bosani Matthieu Allez Peter Laszlo Lakatos Fabrizio Bossa Alexander Eser Tommaso Stefanelli Franck Carbonnel Konstanti | 2009 | Journal of Crohn’s and Colitis2009，，2： | 1 |
| 11 | Tailored treatment according to early post-surgery colonoscopy reduces clinical recurrence in Crohn’s disease: A retrospective study显示文摘 | Clotilde Baudry Benjamin Pariente Nelson Louren?o Marion Simon Mircea Chirica Pierre Cattan Nicolas Munoz-Bongrand Jean-Marc Gornet Matthieu Allez | 2014 | Digestive and Liver Disease2014，，10： | 1 |
| 12 | Prevalence and clinical impact of endoscopic pseudomembranes in patients with inflammatory bowel disease and Clostridium difficile infection显示文摘 | Shomron Ben-Horin Maya Margalit Peter Bossuyt Jochen Maul Yami Shapira Daniela Bojic Irit Chermesh Ahmad Al-Rifai Alain Schoepfer Matteo Bosani Matthieu Allez Peter Laszlo Lakatos Fabrizio Bossa Alexander Eser Tommaso Stefanelli Franck Carbonnel Konstanti | 2009 | Journal of Crohn’s and Colitis2009，，2： | 1 |
| 13 | Combination Immunomodulator and Antibiotic Treatment in Patients With Inflammatory Bowel Disease and Clostridium difficile Infection显示文摘 | Shomron Ben-Horin Maya Margalit Peter Bossuyt Jochen Maul Yami Shapira Daniela Bojic Irit Chermesh Ahmad Al-Rifai Alain Schoepfer Matteo Bosani Matthieu Allez Peter Laszlo Lakatos Fabrizio Bossa Alexander Eser Tommaso Stefanelli Franck Carbonnel Konstanti | 2009 | Clinical Gastroenterology and Hepatology2009，，9： | 1 |
| 14 | Enteropathy associated T cell lymphoma in celiac disease: A large retrospective study显示文摘 | Georgia Malamut Olivia Chandesris Virginie Verkarre Bertrand Meresse Céline Callens Elizabeth Macintyre Yoram Bouhnik Jean-Marc Gornet Matthieu Allez Raymond Jian Anne Berger Gilles Chatellier Nicole Brousse Olivier Hermine Nadine Cerf-Bensussan Christoph | 2012 | Digestive and Liver Disease2012，，： | 1 |
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