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| 1 | Age,smoking and overweight contribute to the development of intestinal metaplasia of the cardia显示文摘AIM:To assess the role of Helicobacter pylori(H.pylori),gastroesophageal reflux disease(GERD),age,smoking and body weight on the development of intestinal metaplasia of the gastric cardia(IMC).METHODS:Two hundred and seventeen patients scheduled for esophagogastroduodenoscopy were enrolled in this study.Endoscopic biopsies from the esophagus,gastroesophageal junction and stomach were evaluated for inflammation,the presence of H.pylori and intestinal metaplasia.The correlation of these factors with the presence of IMC was assessed using logistic regression.RESULTS:IMC was observed in 42% of the patients.Patient age,smoking habit and body mass index(BMI) were found as potential contributors to IMC.The risk of developing IMC can be predicted in theory by combining these factors according to the following formula:Risk of IMC = a + s-2B where a = 2,…6 decade of age,s = 0 for non-smokers or ex-smokers,1 for < 10 cigarettes/d,2 for > 10 cigarettes/d and B = 0 for BMI < 25 kg/m2(BMI < 27 kg/m2 in females),1 for BMI > 25 kg/m2(BMI > 27 kg/m2 in females).Among potential factors associated with IMC,H.pylori had borderline signif icance(P = 0.07),while GERD showed no signif icance.CONCLUSION:Age,smoking and BMI are potential factors associated with IMC,while H.pylori and GERD show no significant association.IMC can be predicted in theory by logistic regression analysis. | Christian Felley Hanifa Bouzourene Marianne Bründler G VanMelle Antoine Hadengue Pierre Michetti Gian Dorta Laurent Spahr Emiliano Giostra Jean Louis Frossard | 2012 | World Journal of Gastroenterology2012，18，17： | 5 |
| 2 | The second European evidence-based Consensus on the diagnosis and management of Crohn’s disease: Current management显示文摘 | A. Dignass G. Van Assche J.O. Lindsay M. Lémann J. S?derholm J.F. Colombel S. Danese A. D’Hoore M. Gassull F. Gomollón D.W. Hommes P. Michetti C. O’Morain T. ?resland A. Windsor E.F. Stange S.P.L. Travis | 2010 | Journal of Crohn’s and Colitis2010，，1： | 2 |
| 3 | Medical progress:Helicobacter pylori infection显示文摘 | Suerbaum Sebastian Michetti Pierre | 2002 | N Engl J Med2002，347，15： | 2 |
| 4 | The S100B protein in biological fluids: more than a lifelong biomarker of brain distress显示文摘 | Michetti F Corvino V Geloso M C | 2012 | J eurochem2012，120，5： | 1 |
| 5 | Gene expression profile of adult human olfactory bulb and embryonic neural stem cell suggests distinct signaling pathways and epigenetic control显示文摘 | Marei HE Ahmed AE Michetti F | 2012 | PLo S One2012，7，33： | 1 |
| 6 | Amniotic fluid S100B protein in mid-gestation and intrauterine fetal death显示文摘 | Michetti F Bruschettini M | 2004 | Lancet2004，364，9430： | 1 |
| 7 | Immunology of Helicobacter pylori Infection显示文摘 | Velin D Michetti P | 2006 | Digestion2006，73，23： | 1 |
| 8 | Analytical model of one-dimen- sional carbon-based schottky-barrier transistors 显示文摘 | MICHETTI P IANNACCONE G | 2010 | IEEE Transac- tions on Electron Devices2010，57，7： | 1 |
| 9 | Reversible inactivation ofcalpain isoforms by nitric oxide显示文摘 | Michetti M Salamino F Melloni E Pontremoli S | 1995 | Biochem Biophys Res Commun1995，207，3： | 1 |
| 10 | Oral immunization with urease and Eschechia Coli heat-labile enterotoxin is safe and immunogenic in Helicobacter pylori-infected adults显示文摘 | Michetti P Kreiss C Kotloff KL | 1999 | Gastroenterology1999，116，4： | 1 |
| 11 | Helicobacter pylori infection显示文摘 | Suerbaum S Michetti P | 2002 | N Engl J Med2002，347，15： | 1 |
| 12 | Helicobacter pylori infection显示文摘 | Suerbaum S Michetti P | 2002 | N Engl J Med2002，347，15： | 1 |
| 13 | Probiotics: wanted dead or alive显示文摘 | Mottet T Michetti P | 2005 | Dig Liver Dis2005，37，： | 1 |
| 14 | S100B protein in biological fluids:a tool for perinatal medicine 显示文摘 | Michetti F Gazzolo D | 2002 | Clin Chem2002，48，12： | 1 |
| 15 | Oral immunization with urease and Escherichia coli heatlabile enterotoxin is safe and immunogenic in Heliobacter pylori-infected adults 显示文摘 | Michetti P Kreiss C Kotloff KL Pota N Bachmann D Herranz M | 1999 | Gastroenterology1999，116，4： | 1 |
| 16 | S-100β protein in biological fluids: a tool for perinatal medicine显示文摘 | Michetti F Gazzolo D | 2007 | Clinical Chemistry2007，48，： | 1 |
| 17 | A bacterial lysate broncho-vaxom in chronic bronchitis:a multicentre,double-blind,clinical trial显示文摘 | Messerli C Michetti F Sauser-Hall P | 1981 | Rev Med Suisse Romande1981，101，： | 1 |
| 18 | Trimethyltin-induced hippocam-pal degeneration as a tool to investigate neurodegerative processes显示文摘 | Geloso MC Corvino V Michetti F | | 0，，07： | 1 |
| 19 | S100B protein in biological fluids: a tool for perinatal medicine 显示文摘 | Michetti F Gazzolo D | 2002 | Clin Chem2002，48，12： | 1 |
| 20 | Mechanism of Action ff a New Component ff the Ca2 + - Dependent Proteolytic System in Rat Brain : The Calpain Avtivator 显示文摘 | Melloni E Michetti M Sa]amino F and Sparatpm B | 1998 | Biochemical and Biophysical Communications1998，，249： | 1 |
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