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115篇 您的检索式:作者名="Mark Howard"
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1GRADE指南:Ⅲ.证据质量分级显示文摘本文介绍证据质量分级的GRADE方法。GRADE将证据质量分为高、中、低和极低四个级别。该分级应用于证据群,而非针对个别研究。系统评价中,质量反映了我们认为效应估计值正确的把握度。对推荐意见而言,质量反映了我们认为效应估计值足以支持某特定推荐的把握度。随机对照试验初定为高质量证据,观察性研究初定为低质量证据。GRADE中所使用的质量一词不只是意味着偏倚风险,还可能受研究结果的不精确性、不一致性和间接性,及发表偏倚的影响。此外,若干因素可增加我们对效应估计值的把握度。GRADE提供了一种系统方法来思考并报告各因素。GRADE将评估证据质量的过程与给出推荐建议的过程分开。推荐强度的判断不仅依赖于证据质量。Howard Balshem Mark Helfanda Holger J.Schunemann Andrew D.Oxman Regina Kunz Jan Brozek Gunn E.Vist Yngve Falck-Ytter Joerg Meerpohl Susan Norris Gordon H.Guyatt GRADE工作组 李幼平 杨晓妍 高霑 2011中国循证医学杂志2011,11,4:128
2缺血性卒中的一级预防——美国心脏协会/美国卒中协会卒中委员会指南 动脉粥样硬化性周围血管病跨学科工作组、心血管护理委员会、临床心脏病学委员会、营养、体力活动和代谢委员会以及医疗质量和转归研究跨学科工作组共同倡导显示文摘背景和目的本指南提供有关各种确定和潜在的卒中危险因素证据的概述,并提供降低卒中风险的推荐。方法写作组成员由委员会主席根据每位作者先前在相关课题领域中的工作提名,并经美国心脏协会(AHA)卒中委员会科学声明监督委员会批准。写作组采用系统文献回顾(涵盖时间段为2001年最后一次回顾发表到2005年1月),参考先前已发表的指南、个人文件和专家意见来概括现有的证据,指明现有知识的差距;如果合适,则根据标准的AHA标准做出简明的推荐。写作组全体成员在撰写过程中均有很多机会对推荐进行评论并认可这份声明的最终版本。在AHA科学咨询与协调委员会批准之前,本指南已进行过广泛的同行评议。结果对评价个体首次卒中风险的流程图进行评估。根据干预的可能性(不可干预、可干预或潜在可干预)和证据的强度(证据充分或证据不太充分),对首次卒中的危险因素或风险标记物进行分类。不可干预的危险因素包括年龄、性别、出生体重低、人种/种族和遗传因素。证据充分的可干预危险因素包括高血压、主动或被动吸烟、糖尿病、心房颤动和某些其他心脏病、血脂异常、颈动脉狭窄、镰状细胞病、绝经后激素治疗、不良饮食习惯、缺乏体力活动、肥胖和体脂分布。证据不太充分或潜在的可干预危险因素包括代谢综合征、酗酒、药物滥用、口服避孕药、睡眠呼吸障碍、偏头痛、高同型半胱氨酸血症、脂蛋白(a)升高、脂蛋白相关的磷脂酶升高、高凝状态、炎症和感染。对应用阿司匹林进行卒中一级预防的资料进行回顾。结论有大量证据可以用于确定增加首次卒中风险的各种特殊因素和提供降低这种风险的策略。Larry B. Goldstein Robert Adams Mark J. Alberts Lawrence J. Appel Lawrence M. Brass Cheryl D. Bushnell Antonio Culebras Thomas J. DeGraba Philip B. Gorelick John R. Guyton Robert G. Hart George Howard Margaret Kelly-Hayes J.V. (Ian) Nixon Ralph L. Sacco 苏克江 高宗恩 2006国际脑血管病杂志2006,14,8:28
3卒中一级预防指南 美国心脏协会/美国卒中协会为医疗卫生专业人员制定的指南美国神经病学学会肯定本指南作为神经科医生继续教育工具的价值显示文摘背景和目的本指南对各种已确定和新出现的卒中危险因素的证据进行概述,以提供降低首次卒中风险的循证推荐。方法写作组成员由委员会主席根据每位成员先前在相关课题领域中的工作提名,并经美国心脏协会(American HeartAssociation,AHA)卒中委员会科学声明监督委员会批准。写作组采用系统文献回顾的方法(涵盖时间为2006年上一次回顾发表到2009年4月),参考先前已发表的指南、个人文件和专家意见来总结现有证据,并指出现有知识的差距;如果合适,则根据标准的AHA标准做出推荐。写作组全体成员均有机会对推荐进行评论并审核这份声明的最终文本。在AHA科学咨询和协调委员会考察和批准之前,本指南已南卒中委员会领导层和AIIA科学声明督察委员会进行过广泛的同行评议。结果对评价个体首次卒巾风险的流程图进行了评价。根据干预的町能性(不可于预、可于预或潜在可干预)和证据的强度(证据充分或证据不太充分),对首次卒中的危险因素或风险标记物进行分类。不可干预危险因素包括年龄、性别、低出生体质量、人种/种族和遗传倾向。证据充分的叮干预危险因素包括高血压、吸烟、糖尿病、心房颤动和某些其他心脏病、血脂异常、颈动脉狭窄、镰状细胞病、绝经后激素治疗、不良饮食习惯、体力活动过少以及肥胖和体脂分布。证据不太充分或潜在的可干预危险因素包括代谢综合征、酗酒、药物滥用、口服避孕药、睡眠呼吸障碍、偏头痛、高同型半胱氨酸血症、脂蛋白(a)升高、高凝状态、炎症和感染。对用阿司匹林进行卒中一级预防的资料进行了回顾。结论多方面的证据可用于确定能增高首次卒中风险的多种具体因素并提供降低这种风险的策略。Larry B. Goldstein Cheryl D. Bushnell Robert J. Adams Lawrence J. Appel Lynne T. Braun Seemant Chaturvedi Mark A. Creager Antonio Culebras Robert H. Eckel Robert G. Hart Judith A. Hinchey Virginia J. Howard Edward C. Jauch Steven R. Levine James F. Meschia Wesley S. Moore J.V. (Ian) Nixon Thomas A. Pearson 张霞(译) 尤寿江(译) 陈孝东(译) 卢涛声(译) 石际俊(译) 曹勇军(译) 徐兴顺(译) 2010国际脑血管病杂志2010,18,12:12
4Guidelines for the Primary Prevention of Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association显示文摘Larry B. Goldstein Cheryl D. Bushnell Robert J. Adams Lawrence J. Appel Lynne T. Braun Seemant Chaturvedi Mark A. Creager Antonio Culebras Robert H. Eckel Robert G. Hart Judith A. Hinchey Virginia J. Howard Edward C. Jauch Steven R. Levine James F. Meschi 2011Stroke2011,,2:6
5Ability of bone graft substitutes to support the osteoprogenitor cells: An in-vitro study显示文摘AIM: To compare seven commercially available bone graft substitutes(BGS) in terms of these properties and without using any additional biological growth factors.METHODS: Porcine osteoprogenitor cells were loaded on seven commercially available BGS and allowed to proliferate for one week followed by osteogenic induction. Staining for live/dead cells as well as scanning electron microscopy(SEM) was carried out to determine viability and cellular binding. Further outcome measures included alkaline phosphatase(ALP) assays with normalisation for DNA content to quantify osteogenic potential. Negative and positive control experiments were carried out in parallel to validate the results.RESULTS: Live/dead and SEM imaging showed higher viability and attachment with β-tricalcium phosphate(β-TCP) than with other BGS(P < 0.05). The average ALP activity in nmol/mL(normalised value for DNA content in nmol/μg DNA) per sample was 657.58(132.03) for β-TCP, 36.22(unable to normalise) for calcium sulphate, 19.93(11.39) for the Hydroxyapatite/Tricalcium Phosphate composite, 14.79(18.53) for polygraft, 13.98(8.15) for the highly porous β-Tricalcium Phosphate, 5.56(10.0) for polymers, and 3.82(3.8) for Hydroxyapatite.CONCLUSION: Under the above experimental conditions, β-TCP was able to maintain better the viability of osteoprogenitor cells and allow proliferation and differentiation(P < 0.05).Ziad Dahabreh Michalis Panteli Ippokratis Pountos Mark Howard Peter Campbell Peter V Giannoudis 2014World Journal of Stem Cells2014,6,4:3
6Consensus Panel Recommendation for Incorporating Lipoprotein-Associated Phospholipase A 2 Testing into Cardiovascular Disease Risk Assessment Guidelines显示文摘Michael H. Davidson Marshall A. Corson Mark J. Alberts Jeffrey L. Anderson Philip B. Gorelick Peter H. Jones Amir Lerman Joseph P. McConnell Howard S. Weintraub 2008The American Journal of Cardiology2008,,12:3
7Organ Injury Scaling: Spleen and Liver (1994 Revision)显示文摘Ernest E. Moore Thomas H. Cogbill Gregory J. Jurkovich Steven R. Shackford Mark A. Malangoni Howard R. Champion 1995The Journal of Trauma: Injury, Infection, and Cri1995,,:2
82011 Update to The Society of Thoracic Surgeons and the Society of Cardiovascular Anesthesiologists Blood Conservation Clinical Practice Guidelines ? ? The International Consortium for Evidence Based Perfusion formally endorses these guidelines.显示文摘Victor A. Ferraris Jeremiah R. Brown George J. Despotis John W. Hammon T. Brett Reece Sibu P. Saha Howard K. Song Ellen R. Clough Linda J. Shore-Lesserson Lawrence T. Goodnough C. David Mazer Aryeh Shander Mark Stafford-Smith Jonathan Waters Robert A. Bak 2011The Annals of Thoracic Surgery2011,,3:2
9Association Between Human Immunodeficiency Virus Infection and Stiffness of the Common Carotid Artery显示文摘Eric C. Seaberg Lorie Benning A. Richey Sharrett Jason M. Lazar Howard N. Hodis Wendy J. Mack Mark J. Siedner John P. Phair Lawrence A. Kingsley Robert C. Kaplan 2010Stroke2010,,10:1
10New acetyls techonologies from BP chemicals显示文摘Mark J Howard Glenn J Sunley Andrew D Poole Robert J Watt Bhushan K Sharma 1999Studies in Surface Science and Catalysis1999,,:1
11Analysis of noise in Fourier transform infrared spectra显示文摘Howard L Mark Peter Grifiths R 2002Applied Spectroscopy2002,56,5:1
12A mutation in PCSK9 causing autosomal-dominant hypercholesterolemia in a Utah pedigree显示文摘Kirsten M. Timms Susanne Wagner Mark E. Samuels Kristian Forbey Howard Goldfine Srikanth Jammulapati Mark H. Skolnick Paul N. Hopkins Steve C. Hunt Donna M. Shattuck 2004Human Genetics2004,,:1
13Towards an operations strate- gy for product-centric servitization显示文摘Tim Baines Howard Lighffoot Joe Peppard Mark Johnson Ashutosh Tiwari Essam Shehab 2009International Journal of Operations & Production Management2009,29,5:1
14Overexpression of CXCL5 Is Associated With Poor Survival in Patients With Pancreatic Cancer显示文摘Aihua Li Jonathan King Aune Moro Mark D. Sugi David W. Dawson Jeffrey Kaplan Gang Li Xuyang Lu Robert M. Strieter Marie Burdick Vay Liang W. Go Howard A. Reber Guido Eibl O. Joe Hines 2011The American Journal of Pathology2011,,3:1
15Bioanalytical Method Validation—A Revisit with a Decade of Progress显示文摘Vinod P. Shah Kamal K. Midha John W. A. Findlay Howard M. Hill James D. Hulse Iain J. McGilveray Gordon McKay Krys J. Miller Rabindra N. Patnaik Mark L. Powell Alfred Tonelli C. T. Viswanathan Avraham Yacobi 2000Pharmaceutical Research2000,,12:1
16Cervical spondyloticmyleopathy-current concept review显示文摘Mark B Richard A Howard W 2004Bone&Joint Surg2004,,:1
17Subtotal hysterectomy in modern gynecology: A decision analysis显示文摘James R. Scott Howard T. Sharp Mark K. Dodson Peggy A. Norton Homer R. Warner 1997American Journal of Obstetrics and Gynecology1997,,6:1
18The Roles of Social Support and Self-Efficacy in Physical Health’s Impact on Depressive and Anxiety Symptoms in Older Adults显示文摘Amber L. Paukert Jeremy W. Pettit Mark E. Kunik Nancy Wilson Diane M. Novy Howard M. Rhoades Anthony J. Greisinger Oscar A. Wehmanen Melinda A. Stanley 2010Journal of Clinical Psychology in Medical Settings2010,,4:1
19Randomized, Phase II Trial of Pemetrexed and Carboplatin with or without Enzastaurin versus Docetaxel and Carboplatin as First-Line Treatment of Patients with Stage IIIB/IV Non-small Cell Lung Cancer显示文摘Mark A. Socinski Robert N. Raju Thomas Stinchcombe Darren M. Kocs Linda S. Couch David Barrera Steven R. Rousey Janak K. Choksi Robert Jotte Debra A. Patt Phillip O. Periman Howard R. Schlossberg Charles H. Weissman Yunfei Wang Lina Asmar Sharon Pritchard 2010Journal of Thoracic Oncology2010,,:1
20Methylprednisolone and cyclophosphamide, alone or in combination, in patients with lupus nephritis 显示文摘Mark FGourle Y Howard A Austin Ⅲ Dorothy Scorr 1996Ann Intern Med1996,125,7:1
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