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| 1 | Colorectal liver metastases: Current management and future perspectives显示文摘The liver is the commonest site of metastatic disease for patients with colorectal cancer,with at least 25%developing colorectal liver metastases(CRLM)during the course of their illness.The management of CRLM has evolved into a complex field requiring input from experienced members of a multi-disciplinary team involving radiology(cross sectional,nuclear medicine and interventional),Oncology,Liver surgery,Colorectal surgery,and Histopathology.Patient management is based on assessment of sophisticated clinical,radiological and biomarker information.Despite incomplete evidence in this very heterogeneous patient group,maximising resection of CRLM using all available techniques remains a key objective and provides the best chance of long-term survival and cure.To this end,liver resection is maximised by the use of downsizing chemotherapy,optimisation of liver remnant by portal vein embolization,associating liver partition and portal vein ligation for staged hepatectomy,and combining resection with ablation,in the context of improvements in the functional assessment of the future remnant liver.Liver resection may safely be carried out laparoscopically or open,and synchronously with,or before,colorectal surgery in selected patients.For unresectable patients,treatment options including systemic chemotherapy,targeted biological agents,intraarterial infusion or bead delivered chemotherapy,tumour ablation,stereotactic radiotherapy,and selective internal radiotherapy contribute to improve survival and may convert initially unresectable patients to operability.Currently evolving areas include biomarker characterisation of tumours,the development of novel systemic agents targeting specific oncogenic pathways,and the potential reemergence of radical surgical options such as liver transplantation. | Jack Martin Angelica Petrillo Elizabeth C Smyth Nadeem Shaida Samir Khwaja HK Cheow Adam Duckworth Paula Heister Raaj Praseedom Asif Jah Anita Balakrishnan Simon Harper Siong Liau Vasilis Kosmoliaptsis Emmanuel Huguet | 2020 | World Journal of Clinical Oncology2020,11,10: | 5 |
| 2 | 18F-fluorodeoxyglucose positron emission tomography in management of pancreatic cystic tumors显示文摘 | Yaojun Zhang Adam E. Frampton Jack L. Martin Charis Kyriakides Jan Jin Bong Nagy A. Habib Panagiotis Vlavianos Long R. Jiao | 2012 | Nuclear Medicine and Biology2012,,7: | 2 |
| 3 | The diagnosis of dementia due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer’s disease显示文摘 | Guy M. McKhann David S. Knopman Howard Chertkow Bradley T. Hyman Clifford R. Jack Claudia H. Kawas William E. Klunk Walter J. Koroshetz Jennifer J. Manly Richard Mayeux Richard C. Mohs John C. Morris Martin N. Rossor Philip Scheltens Maria C. Carrillo Bil | 2011 | Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association2011,,3: | 2 |
| 4 | Liver regeneration biology:Implications for liver tumour therapies显示文摘The liver has remarkable regenerative potential,with the capacity to regenerate after 75%hepatectomy in humans and up to 90%hepatectomy in some rodent models,enabling it to meet the challenge of diverse injury types,including physical trauma,infection,inflammatory processes,direct toxicity,and immunological insults.Current understanding of liver regeneration is based largely on animal research,historically in large animals,and more recently in rodents and zebrafish,which provide powerful genetic manipulation experimental tools.Whilst immensely valuable,these models have limitations in extrapolation to the human situation.In vitro models have evolved from 2-dimensional culture to complex 3 dimensional organoids,but also have shortcomings in replicating the complex hepatic micro-anatomical and physiological milieu.The process of liver regeneration is only partially understood and characterized by layers of complexity.Liver regeneration is triggered and controlled by a multitude of mitogens acting in autocrine,paracrine,and endocrine ways,with much redundancy and cross-talk between biochemical pathways.The regenerative response is variable,involving both hypertrophy and true proliferative hyperplasia,which is itself variable,including both cellular phenotypic fidelity and cellular trans-differentiation,according to the type of injury.Complex interactions occur between parenchymal and non-parenchymal cells,and regeneration is affected by the status of the liver parenchyma,with differences between healthy and diseased liver.Finally,the process of termination of liver regeneration is even less well understood than its triggers.The complexity of liver regeneration biology combined with limited understanding has restricted specific clinical interventions to enhance liver regeneration.Moreover,manipulating the fundamental biochemical pathways involved would require cautious assessment,for fear of unintended consequences.Nevertheless,current knowledge provides guiding principles for strategies to optimise liver regeneration potential. | Christopher Hadjittofi Michael Feretis Jack Martin Simon Harper Emmanuel Huguet | 2021 | World Journal of Clinical Oncology2021,12,12: | 2 |
| 5 | Work,family and health:the expanding role of EAP professionals显示文摘 | BEACH R H STEVEN MARTIN K JACK | 1995 | Employee Counselling Today1995,7,4: | 1 |
| 6 | Autobiographical memory, experiential understanding,and knowledge about teaching显示文摘 | Jack Martin | 1999 | Teaching & teacher education1999,,4: | 1 |
| 7 | Diagnosis, assessment, and treatment of bone turnover abnormalities in renal osteodystrophy显示文摘 | Kevin J Martin Klaus Olgaard Jack W Coburn Giorgio M Coen Masafumi Fukagawa Craig Langman Hartmut H Malluche James T McCarthy Shaul G Massry Otto Mehls Isidro B Salusky Justin M Silver Miroslaw T Smogorzewski Eduardo M Slatopolsky Linda McCann | 2004 | American Journal of Kidney Diseases2004,,3: | 1 |
| 8 | Measurements of primary trace gases and NO Y composition in Houston, Texas显示文摘 | Winston T. Luke Paul Kelley Barry L. Lefer James Flynn Bernhard Rappenglück Michael Leuchner Jack E. Dibb Luke D. Ziemba Casey H. Anderson Martin Buhr | 2009 | Atmospheric Environment2009,,33: | 1 |
| 9 | Detecting DNA Methylation of the BCL2 , CDKN2A and NID2 Genes in Urine Using a Nested Methylation Specific Polymerase Chain Reaction Assay to Predict Bladder Cancer显示文摘 | Michael B. Scher Michael B. Elbaum Yakov Mogilevkin David W. Hilbert Jack H. Mydlo A. Ami Sidi Martin E. Adelson Eli Mordechai Jason P. Trama | 2012 | The Journal of Urology2012,,6: | 1 |
| 10 | Electrocardiographic T Wave: A Symbol of Transmural Dispersion of Repolarization in the Ventricles显示文摘 | Ganxin Yah Jack Martin | 2003 | Journal of Cardiovascular Electrophysiology2003,14,6: | 1 |
| 11 | Correlates of satisfaction with body function and body appearance in middle- and older aged adults: The activity counseling trial (ACT)显示文摘 | Beth A. Reboussin W. Jack Rejeski Kathleen A. Martin Kelley Callahan Andrea L. Dunn Abby C. King James F. Sallis | 2000 | Psychology & Health2000,,2: | 1 |
| 12 | Plant Cell显示文摘 | Michael E Horn Barry A Martin Jack M Widholm | 1992 | Tissue and Organ Culture1992,,30: | 1 |
| 13 | A Novel Technique of Needle-guided Laparoscopic Enucleation of Insulinomas显示文摘 | Aggelos Laliotis Jack Martin Tim R. Worthington Michele Marshall Alberto M. Isla | 2015 | Surgical Laparoscopy, Endoscopy & Percutaneous Techniques2015,,1: | 1 |
| 14 | Relationship of Plasma Polyunsaturated Fatty Acids to Circulating Inflammatory Markers显示文摘 | Luigi Ferrucci Antonio Cherubini Stefania Bandinelli Benedetta Bartali Annamaria Corsi Fulvio Lauretani Antonio Martin Cristina Andres-Lacueva Umberto Senin Jack M. Guralnik | 2006 | The Journal of Clinical Endocrinology & Metabolism2006,,2: | 1 |
| 15 | Anton, a special-purpose machine for molecular dynamics simulation显示文摘 | David E. Shaw Martin M. Deneroff Ron O. Dror Jeffrey S. Kuskin Richard H. Larson John K. Salmon Cliff Young Brannon Batson Kevin J. Bowers Jack C. Chao Michael P. Eastwood Joseph Gagliardo J. P. Grossman C. Richard Ho Douglas J. Ierardi István Kolossváry | 2007 | ACM SIGARCH Computer Architecture News2007,,2: | 1 |
| 16 | IPNA临床实践建议:儿童激素敏感型肾病综合征的诊断和治疗显示文摘特发性肾病综合征是最常见的儿童肾小球疾病,其特征是大量蛋白尿、低蛋白血症和(或)伴有水肿,全球每年儿童患病率为(1.15~16.90)每10万例。约有85%~90%的患者在接受糖皮质激素治疗的4~6周内可达到蛋白尿完全缓解,表现为激素敏感型肾病综合征(SSNS)。约70%~80%的SSNS患者在随访期间至少复发1次,其中多达50%的患者出现频繁复发或依赖糖皮质激素以维持蛋白尿缓解。为延长复发间隔时间,激素治疗的用药剂量和用药时长始终是热点问题之一,且患者出现激素相关并发症的概率较高。临床已应用多种激素助减药物(免疫抑制药物),但在疾病治疗过程中这些药物的选择和用药时机存在明显差异。因此,需要国际循证临床实践建议(CPRs)来指导临床实践、减少实践差异。国际儿科肾脏病学会(IPNA)召集专家小组通过对12个临床相关PICO(研究对象、干预措施、对照、结果/结局)问题进行系统的文献回顾,制定了关于儿童SSNS诊断和治疗的建议和分级。对治疗转归提出了新的定义,有助于指导治疗改变,并为重要的研究问题提供了参考。 | Agnes Trautmann Olivia Boyer Elisabeth Hodson Arvind Bagga Debbie S.Gipson Susan Samuel Jack Wetzels Khalid Alhas an Sushmita Banerjee Rajendra Bhimma Melvin Bonilla-Felix Francisco Cano Martin Christian Deirdre Hahn Hee Gyung Kang Koichi Nakanishi Hesham Safouh Howard Trachtman Hong Xu Wendy Cook Marina Vivarelli Dieter Hafner on behalf of the International Pediatric Nephrology Association 韩思雨(翻译) 季丽娜(翻译) | 2023 | 中国合理用药探索2023,20,2: | 1 |
| 17 | Accreditation and quality assurance for Radiation Therapy Oncology Group: Multicenter clinical trials using Stereotactic Body Radiation Therapy in lung cancer显示文摘 | Robert Timmerman James Galvin Jeff Michalski William Straube Geoffrey Ibbott Elizabeth Martin Ramzi Abdulrahman Suzanne Swann Jack Fowler Hak Choy | 2006 | Acta Oncologica2006,,7: | 1 |
| 18 | Oxidative stress contributes to the induction and persistence of TGF-β1 induced pulmonary fibrosis显示文摘 | Ye Cui Jennifer Robertson Shyam Maharaj Lisa Waldhauser Jianzhao Niu Jifeng Wang Laszlo Farkas Martin Kolb Jack Gauldie | 2011 | International Journal of Biochemistry and Cell Biology2011,,8: | 1 |
| 19 | Genes mediating programmed cell death: an immunchis to chemical studay of bcl - 2, c - myc and P53 expression in colorectal neoplasis 显示文摘 | Martin I Jack AS | 1996 | J Clin Pathol Mol Pathol1996,49,: | 1 |
| 20 | The diagnosis of dementia due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer’s disease显示文摘 | Guy M. McKhann David S. Knopman Howard Chertkow Bradley T. Hyman Clifford R. Jack Claudia H. Kawas William E. Klunk Walter J. Koroshetz Jennifer J. Manly Richard Mayeux Richard C. Mohs John C. Morris Martin N. Rossor Philip Scheltens Maria C. Carrillo Bil | 2011 | Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association2011,,3: | 1 |