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| 1 | S-acylation-dependent association of the calcium sensor CBL2 with the vacuolar membrane is essential for proper abscisic acid responses显示文摘Calcineurin 象 B 一样(CBL ) 蛋白质贡献由与交往 CBL 蛋白质 kinases (CIPK ) 交往译码钙信号。当前,几乎仍然功能和在 vacuolar 膜是局部性的 CBL 蛋白质的特定的指向机制没有信息。在这研究,我们集中于 CBL2,丰富的 vacuolar 从 Arabidopsis thaliana 的未知功能的膜局部性的钙传感器。我们证明 CBL2 指向的 vacuolar 被三半胱氨酸残余的 S-acylation 明确地在它的 N 终点和那 CBL2 S-acylation 引起并且指向由一条 Brefeldin A 感觉迟钝的小径发生。CBL2 功能的损失在种子萌芽期间并且仅仅充分使植物变为过分敏感到植物激素 abscisic 酸(骆驼毛的织物) S-acylated 和适当地指向 vacuolar 的 CBL2 蛋白质能补充这变异的显型。这些调查结果定义为蛋白质指向小径的 S-acylation-dependent vacuolar 膜并且揭开在骆驼毛的织物回答的 vacuolar 钙传感器的一个关键角色。 | Oliver Batistic Marion Rehers Amir Akerman Kathrin Schlucking Leonie Steinhorst Shaul Yalovsky Jorg Kudla | 2012 | Cell Research2012，22，7： | 12 |
| 2 | Role of c-Abl in the DNA damage stress response显示文摘c-Abl has been implicated in many cellular processes including differentiation, division, adhesion, death, and stress response. c-Abl is a latent tyrosine kinase that becomes activated in response to numerous extra- and intra-cellular stimuli. Here we briefly review the current knowledge about c-Abl involvement in the DNA-damage stress response and its implication on cell physiology. | Yosef SHAUL Merav BEN-YEHOYADA | 2005 | Cell Research2005，15，1： | 5 |
| 3 | Localization of the Arabidopsis Senescence- and Cell Death-Associated BFN1 Nuclease: From the ER to Fragmented Nuclei显示文摘植物联系老朽或联系 PCD 的核酸酶从不同有机体与核酸酶分享重要相同。然而,他们的功能的知识是有限的。Arabidopsis 联系老朽、联系 PCD 的核酸酶 BFN1 的细胞内部的本地化被调查。在短暂地转变的烟草原物的 BFN1GFP 本地化的分析表明在细丝状的结构的起始的本地化在整个细胞质传播了,它然后在原物开始衰老的原子核附近聚类。这些细丝状的结构作为具有被识别嗯起源。在 BFN1GFP 转基因的 Arabidopsis 植物, BFN1GFP 的类似的本地化在年轻叶子被观察,也就是说,在细丝状的结构,那仅仅在开始衰老在原子核附近重新组织房间。在迟了的老朽, BFN1GFP 与在包膜的泡的碎裂的原子核是局部性的。BFN1 的要求的功能作为 nucleic,在老朽和 PCD 的酸降级的酶被它的本地化模式支持。我们的结果建议在老朽和 PCD 的 nucleic 酸降级处理的调停的奉献分隔空间的存在。 | Sarit Farage-Barhom Shaul Burd Lilian Sonego Ana Mett Eduard Belausov David Gidoni Amnon Lers | 2011 | Molecular Plant2011，4，6： | 5 |
| 4 | Nutrient supplemented serum-free medium increases cardiomyogenesis efficiency of human pluripotent stem cells显示文摘AIM: To development of an improved p38 MAPK inhibitor-based serum-free medium for embryoid body cardiomyocyte differentiation of human pluripotent stem cells. METHODS: Human embryonic stem cells (hESC) differentiated to cardiomyocytes (CM) using a p38 MAPK inhibitor (SB203580) based serum-free medium (SB media). Nutrient supplements known to increase cell viability were added to SB medium. The ability of these supplements to improve cardiomyogenesis was evaluated by measurements of cell viability, total cell count, and the expression of cardiac markers via flow cytometry. An improved medium containing Soy hydrolysate (HySoy) and bovine serum albumin (BSA) (SupSB media) was developed and tested on 2 additional cell lines (H1 and Siu-hiPSC). Characterization of the cardiomyocytes was done by immunohistochemistry, electrophysiology and quantitative real-time reverse transcriptionpolymerase chain reaction. RESULTS: hESC cell line, HES-3, differentiating in SB medium for 16 d resulted in a cardiomyocyte yield of 0.07 ± 0.03 CM/hESC. A new medium (SupSB media) was developed with the addition of HySoy and BSA to SB medium. This medium resulted in 2.6 fold increase in cardiomyocyte yield (0.21 ± 0.08 CM/hESC). The robustness of SupSB medium was further demonstrated using two additional pluripotent cell lines (H1, hESC and Siu1, hiPSC), showing a 15 and 9 fold increase in cardiomyocyte yield respectively. The age (passage number) of the pluripotent cells did not affect the cardiomyocyte yields. Embryoid body (EB) cardiomyocytes formed in SupSB medium expressed canonical cardiac markers (sarcomeric α-actinin, myosin heavy chain and troponin-T) and demonstrated all three major phenotypes: nodal-, atrial- and ventricular-like. Electrophysiological characteristics (maximum diastolic potentials and action potential durations) of cardiomyocytes derived from SB and SupSB media were similar. CONCLUSION: The nutrient supplementation (HySoy and BSA) leads to increase in cell viability, cell yield and cardiac marker expression during cardiomyocyte differentiation, translating to an overall increase in cardiomyocyte yield. | Sherwin Ting Marti Lecina Yau-Chi Chan Hung Fat Tse Shaul Reuveny Steve KW Oh | 2013 | World Journal of Stem Cells2013，5，3： | 4 |
| 5 | Synthesis,Contact Printing,and Device Characterization of Ni-Catalyzed,Crystalline InAs Nanowires显示文摘InAs nanowires have been actively explored as the channel material for high performance transistors owing to their high electron mobility and ease of ohmic metal contact formation.The catalytic growth of nonepitaxial InAs nanowires,however,has often relied on the use of Au colloids which is non-CMOS compatible.Here,we demonstrate the successful synthesis of crystalline InAs nanowires with high yield and tunable diameters by using Ni nanoparticles as the catalyst material on amorphous SiO_(2) substrates.The nanowires show superb electrical properties with field-effect electron mobility~2700 cm^(2)/Vs and ION/IOFF>10^(3).The uniformity and purity of the grown InAs nanowires are further demonstrated by large-scale assembly of parallel arrays of nanowires on substrates via the contact printing process that enables high performance,“printable”transistors,capable of delivering 510 mA ON currents(~400 nanowires). | Alexandra C.Ford Johnny C.Ho Zhiyong Fan Onur Ergen Virginia Altoe Shaul Aloni Haleh Razavi Ali Javey | 2008 | Nano Research2008，1，1： | 3 |
| 6 | 伦理学与SARS:多伦多的教训显示文摘SARS的流行说明传染病在世界范围内流行是件多么容易的事,为了更好地应对下一次流行病,我们不仅要解决医学方面的问题,也同样需要解决伦理学方面的问题。 | Peter A Singer Solomon R Benatar Mark Bernstein Abdallah S Daar Bernard M Dickens Susan K MacRae Ross E G Upshur Linda Wright Randi Zlotnik Shaul 肖月 | 2004 | 英国医学杂志中文版2004，7，4： | 3 |
| 7 | 硒化镉量子点在介孔二氧化硅微球中的限制生长以制备多功能纳米结构(英文)显示文摘本文报道了一种新颖且便捷的将荧光半导体纳米晶包覆到二氧化硅球中进而制备多功能纳米结构的方法.从溶胶凝胶法合成二氧化硅微球开始,在聚合物配体保护下进行化学刻蚀从而获得介孔级孔道,然后将带有孔道的二氧化硅微球投入到制备Cd Se量子点的高温反应体系中,就可以直接在二氧化硅微球的孔道中生长尺寸均匀且具有高荧光产率的Cd Se纳米晶.研究发现二氧化硅微球中的孔道对于Cd Se量子点的生长有一定的抑制作用,因此与自由生长的量子点比较其荧光光谱会发生蓝移,二氧化硅微球中负载Cd Se量子点的数量可以通过选择不同刻蚀程度的二氧化硅微球来实现.这种纳米结构优点在于:不需要特殊的表面处理工艺,对于不同形貌及尺寸的二氧化硅微球具有普适性,对于纳米晶与主体材料的尺寸调控具有较高的灵活性,并且可以同时包裹其他功能材料,比如将磁性纳米粒子引入到该体系,合成了兼具磁学与光学性能的Fe3O4@Si O2/Cd Se复合纳米结构材料.该方法为制备多功能复合纳米结构材料提供了一个平台. | 李春光 鲁振达 张桥 葛建平 Shaul Aloni 施展 殷亚东 | 2015 | Science China Materials2015，58，6： | 2 |
| 8 | Browning determination in citrus products显示文摘 | Shaul Meyday | 1977 | J Agric Food Chem1977，25，3： | 1 |
| 9 | Inhibition of hepatitis B virus expression and replication by RNA interference 显示文摘 | Shlomai A Shaul Y | 2003 | Hepatology2003，37，： | 1 |
| 10 | 显示文摘 | Shaul M A | 2001 | Inter J Polymeric Mater2001，50，： | 1 |
| 11 | Inhibition of hepatitis B virus expression and replication by RNA interference显示文摘 | SHLOMAI A SHAUL Y | 2003 | Hepatology2003，37，4： | 1 |
| 12 | Oxidized low density lipoprotein displace endothelial nitrie-ordde syathase (eNOS) from plasmalemmal caveolae and impairs eNOS activation 显示文摘 | Blair A Shaul PW Yuhanna IS | 1999 | J Biol them1999，274，45： | 1 |
| 13 | Inhibition of hepatitis B virus expression replication by RNA interference显示文摘 | Shlomai A Shaul Y | 2003 | Hepatology2003，37，4： | 1 |
| 14 | Fate of water soluble azo dyes in the activated sludge process显示文摘 | SHAUL Glenn M THOMAS J Holdsworth CLYDE R Dempsey Dostal KA | 1991 | Chemosphere1991，22，12： | 1 |
| 15 | Effect of passive smoking in pregnancy on neonatal nucleated red blood cells显示文摘 | Shaul D Ofer F Francis B | 2000 | Pediatr2000，106，3： | 1 |
| 16 | Late-onset bloodstream infections in preterm infants: A 2- year survey显示文摘 | Galia Grisaru-Soen Tal Friedman Shaul Dollberg | 2012 | Pediatrics International2012，54，6： | 1 |
| 17 | HBV transcription repression in response to genotoxic stress in p53 - dependent and abroganted by pX显示文摘 | Doitsh G Shaul Y | 1999 | Oncogene1999，18，： | 1 |
| 18 | Feature Generation for Text Categorization Using World Knowledge显示文摘 | Evgeniy Gabrilovich Shaul Markovitch | 2005 | IJCAI2005，，： | 1 |
| 19 | HBXAP, a novel PHD-fin- ger protein, possesses transcription repression activity显示文摘 | Shamay M Barak O Shaul Y | 2002 | Genomics2002，79，4： | 1 |
| 20 | Demonstration That C-Reactive Protein Decreases eNOS Expression and Bioactivity in Human Aortic Endothelial Cells显示文摘 | Senthil Kumar Venugopal Sridevi Devaraj Ivan Yuhanna Philip Shaul Ishwarlal Jialal | 2002 | Circulation: Journal of the American Heart Association2002，，12： | 1 |
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