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| 1 | Fecal microbiota transplantation as novel therapy in gastroenterology:A systematic review显示文摘AIM:To study the clinical efficacy and safety of Fecal microbiota transplantation(FMT).We systematically reviewed FMT used as clinical therapy.METHODS:We searched MEDLINE,EMBASE,the Cochrane Library and Conference proceedings from inception to July,2013.Treatment effect of FMT was calculated as the percentage of patients who achieved clinical improvement per patient category,on an intention-to-treat basis.RESULTS:We included 45 studies;34 on Clostridium difficile-infection(CDI),7 on inflammatory bowel disease,1 on metabolic syndrome,1 on constipation,1 on pouchitis and 1 on irritable bowel syndrome(IBS).In CDI 90% resolution of diarrhea in 33 case series(n = 867) was reported,and 94% resolution of diarrhea after repeated FMT in a randomized controlled trial(RCT)(n = 16).In ulcerative colitis(UC) remission rates of 0% to 68% were found(n = 106).In Crohn's disease(CD)(n = 6),no benefit was observed.In IBS,70% improvement of symptoms was found(n = 13).100% Reversal of symptoms was observed in constipation(n = 3).In pouchitis,none of the patients(n = 8) achieved remission.One RCT showed significant improvement of insulin sensitivity in metabolic syndrome(n = 10).Serious adverse events were rare.CONCLUSION:FMT is highly effective in CDI,and holds promise in UC.As for CD,chronic constipation,pouchitis and IBS data are too limited to draw conclusions.FMT increases insulin sensitivity in metabolic syndrome. | Noortje G Rossen John K Mac Donald Elisabeth M de Vries Geert R D'Haens Willem M de Vos Erwin G Zoetendal Cyriel Y Ponsioen | 2015 | World Journal of Gastroenterology2015，21，17： | 41 |
| 2 | Mechanism of friction reduction of unsaturated fatty acids as additives in diesel fuels显示文摘This paper investigates the effect of unsaturated fatty acid additives on the lubricating properties of a biodiesel,composed of a blend of fatty acid methyl esters(FAMEs)and a conventional diesel fuel.The presence of fatty acids as additives for biodiesel improves their lubricating properties at elevated temperature conditions.The formation of a protective lubricating tribochemical film on the steel contact surfaces has been evidenced.Elevated temperature conditions and possibly oxygen are needed to form this film that reduces friction and limits wear.Several analytical tools have revealed the insulating nature of the formed tribofilm and its chemical properties.Friction-induced reticulation is thought to play a major role in the growth of this insulating film. | Jean Michel MARTIN Christine MATTA Maria-Isabel De Barros BOUCHET Cyrielle FOREST Thierry Le MOGNE Thomas DUBOIS Michael MAZARIN | 2013 | Friction2013，1，3： | 7 |
| 3 | Adalimumab for Crohn’s disease: Long-term sustained benefit in a population-based cohort of 438 patients显示文摘 | Charlotte P. Peters Emma J. Eshuis Florien M. Toxopeüs Merel E. Hellemons Jeroen M. Jansen Geert R.A.M. D’Haens Paul Fockens Pieter C.F. Stokkers Hans A.R.E. Tuynman Adriaan A. van Bodegraven Cyriel Y. Ponsioen | 2014 | Journal of Crohn’s and Colitis2014，，： | 2 |
| 4 | Expression and activation of NF-KB in the antrum of the human stomach 显示文摘 | Gijs R Fiedo J Cyriel Y | 2000 | J Immunol2000，164，6： | 1 |
| 5 | Putting a spin on the dorsal–ventral divide of the striatum显示文摘 | Pieter Voorn Louk J.M.J Vanderschuren Henk J Groenewegen Trevor W Robbins Cyriel M.A Pennartz | 2004 | Trends in Neurosciences2004，，8： | 1 |
| 6 | Cellulase-assisted release of secoisolariciresinol fromextracts of flax(linumusitatissimum)hulls and whole seeds显示文摘 | Sullivan Renouard Christophe Hano Cyrielle Corbin etal | 2010 | Food Chemistry2010，122，： | 1 |
| 7 | RNAi-mediated pinoresinol lariciresinol reductase gene silencing in flax ( Linum usitatissimum L.) seed coat: Consequences on lignans and neolignans accumulation显示文摘 | Sullivan Renouard Marie-Aude Tribalatc Frederic Lamblin Ga?lle Mongelard Ophélie Fliniaux Cyrielle Corbin Djurdjica Marosevic Serge Pilard Hervé Demailly Laurent Gutierrez Christophe Hano Fran?ois Mesnard Eric Lainé | 2014 | Journal of Plant Physiology2014，，15： | 1 |
| 8 | Expression and activation of NF к B in the antrum of the human stomach显示文摘 | Gijs R Fiedo J Cyriel Y | 2000 | J Immunol2000，164，： | 1 |
| 9 | Single-port versus multiport laparoscopic ileocecal resection for Crohn’s disease显示文摘 | Tjibbe J. Gardenbroek Tessa Verlaan Pieter J. Tanis Cyriel Y. Ponsioen Geert R.A.M. D’Haens Christianne J. Buskens Willem A. Bemelman | 2013 | Journal of Crohn’s and Colitis2013，，： | 1 |
| 10 | Impact of disease location on fecal calprotectin levels in Crohn’s disease显示文摘 | Krisztina B. Gecse Johannan F. Brandse Sandra van Wilpe Mark Lö wenberg Cyriel Ponsioen Gijs van den Brink Geert D’ Haens | 2015 | Scandinavian Journal of Gastroenterology2015，，7： | 1 |
| 11 | 157 Fecal Loss of Infliximab As a Cause of Lack of Response in Severe Inflammatory Bowel Disease显示文摘 | Johannan F Brandse Manon Wildenberg Jessica R. de Bruyn Gert-Jan Wolbink M. Lowenberg Cyriel Ponsioen Gijs R. van den Brink Geert R. D’Haens | 2013 | Gastroenterology2013，，5： | 1 |
| 12 | Less adhesiolysis and hernia repair during completion proctocolectomy after laparoscopic emergency colectomy for ulcerative colitis显示文摘 | Sanne A. L. Bartels Malaika S. Vlug Daan Henneman Cyriel Y. Ponsioen Pieter J. Tanis Willem A. Bemelman | 2012 | Surgical Endoscopy2012，，2： | 1 |
| 13 | Prior Colorectal Neoplasia Is Associated With Increased Risk of Ileoanal Pouch Neoplasia in Patients With Inflammatory Bowel Disease显示文摘 | Lauranne A.A.P. Derikx Wietske Kievit Joost P.H. Drenth Dirk J. de Jong Cyriel Y. Ponsioen Bas Oldenburg Andrea E. van der Meulen–de Jong Gerard Dijkstra Marina J.A.L. Grubben Cornelis J.H.M. van Laarhoven Iris D. Nagtegaal Frank Hoentjen | 2014 | Gastroenterology2014，，： | 1 |
| 14 | Primary sclerosing cholangitis is associated with a distinct phenotype of inflammatory bowel disease显示文摘 | Kirsten Boonstra Karel J. van Erpecum Karin M.J. van Nieuwkerk Joost P.H. Drenth Alexander C. Poen Ben J.M. Witteman Hans A.R.E. Tuynman Ulrich Beuers Cyriel Y. Ponsioen | 2012 | Inflamm Bowel Dis2012，，12： | 1 |
| 15 | Phospholipid fingerprints of milk from different mammalians determined by 31P NMR: Towards specific interest in human health显示文摘 | CYRIELLE G NORBERT W L SYLVIANE C G | 2012 | Food Chemistry2012，135，3： | 1 |
| 16 | Current issues in packet switch design显示文摘 | Cyriel Minkenberg Ronald P. Luijten Fran?ois Abel Wolfgang Denzel Mitchell Gusat | 2003 | ACM SIGCOMM Computer Communication Review2003，，1： | 1 |
| 17 | Findings From a Randomized Controlled Trial of Fecal Transplantation for Patients With Ulcerative Colitis显示文摘 | Noortje G. Rossen Susana Fuentes Mirjam J. van der Spek Jan G. Tijssen Jorn H.A. Hartman Ann Duflou Mark L?wenberg Gijs R. van den Brink Elisabeth M.H. Mathus-Vliegen Willem M. de Vos Erwin G. Zoetendal Geert R. D’Haens Cyriel Y. Ponsioen | 2015 | Gastroenterology2015，，： | 1 |
| 18 | Epidemiology of primary sclerosing cholangitis and primary biliary cirrhosis: A systematic review显示文摘 | Kirsten Boonstra Ulrich Beuers Cyriel Y. Ponsioen | 2012 | Journal of Hepatology2012，，5： | 1 |
| 19 | Low and high gamma oscillations in rat ventral Striatum have distinct relationships to beharior,reward,and spiking activity on a learned spatial Decision task显示文摘 | Cyriel MA Pennartz | | 0，，： | 1 |
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