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| 1 | Acute uyeloid leukemia and acute promyelocytie leukemia显示文摘 | Lowenberg B Griffin JD Tallman MS | 2003 | Hematology2003，，： | 2 |
| 2 | Immune response-related genes associated to blocking midgut dengue virus infection in Aedes aegypti strains that differ in susceptibility显示文摘Aedes (Stegomyia) aegypti, the principal global vector of dengue viruses, has difTerences in its susceptibility to dengue virus infection. We compared the global expres? sion of genes in the midguts of Colombian Ae. aegypti dengue-susceptible (Cali-S) and dengue-refractory (Cali-MIB) field derived strains after ingesting either a sugarmeal, a bloodmeal, or a bloodmeal containing dengue virus serotype 2 (DENV-2). Microarraybased transcriptome analysis among treatments indicated a total of 4725 transcripts with differential expression between the two strains. Eleven genes were selected from different functional groups based on their significant up or down expression levels as well as reports in the literature suggesting they are associated with dengue virus elimination. We measured mRNA abundance of these 11 genes at 0, 8, 24, and 36 h postinfection using quantitative real time PCR (qPCR) to confirm the microarray results and assess any temporal patterns. Four genes were selected (Gram-negative binding protein—GNBP [AAEL009176], Niemann Pick Type-C2一NPC2 [AAEL015136], Keratinocyte lectin [AAEL009842], and Cathepsin-b [AAEL007585]) for knockdown experiments using RNA interference (RNAi) methodology to determine the phenotype (DENV-2 susceptible or refractory). Silencing GNBP、Cathepsin-b and Keratinocyte lectin reduced the percentage of mosquitoes with disseminated virus in the Cali-S strain to 8%, 20%, and 12% respectively compared with 96% in the controls. Sile ncing of NPC2 increased the percentage of mosquitos with disseminated virus infections in Cali-MIB to 66% compared with 35% in the controls. This study provides in sight into genes that may contribute to the Cali-S susceptible and Cali-MIB refractory phenotypes in 昇匕 aegypti. | Paola A. Caicedo Idalba Mildred Serrato Shuzhen Sim George Dimopoulos Heather Coatsworth Carl Lowenberger Clara B. Ocampo | 2019 | Insect Science2019，26，4： | 2 |
| 3 | Cognitive load selectively interferes with utilitarian moral judgment显示文摘 | Joshua D. Greene Sylvia A. Morelli Kelly Lowenberg Leigh E. Nystrom Jonathan D. Cohen | 2007 | Cognition2007，，3： | 2 |
| 4 | Thrombocytopenia in critically ill patients显示文摘 | Levi M Lowenberg EC | 2008 | Seminars in Thrombosis & Hemostasis2008，34，5： | 1 |
| 5 | On the value of inten- sive remission-induction chemotherapy in elderly patients of 65 + years withacute myeloid leukemia: a randomized phase Ⅲ study of the European Organizationfor Research and Treatment of Cancer Leukemia Group 显示文摘 | Lowenberg B Zittoun R Kerkhofs H | 1989 | J Clin Oncol1989，7，9： | 1 |
| 6 | Inhibition of the intrinsic coagulation pathway factor Ⅺ by antisense oligonucleotides:a novel antithrombotic strategy with lowered bleeding risk显示文摘 | Zhang H Lowenberg EC Crosby JR | 2010 | Blood2010，116，22： | 1 |
| 7 | High-Dose daunorubicin in older patients with acute myeloid leukemia显示文摘 | Lowenberg B Ossenkoppele GJ van Putten W | 2009 | N Engl J Med2009，361，13： | 1 |
| 8 | Paravascular cells in endosteal spaces of alveolar bone contribute to periodontal ligament cell populations显示文摘 | McCulloch CA Nemeth E Lowenberg B Melcher AH | 1987 | Anat Rec1987，219，3： | 1 |
| 9 | Hematopoietic growth factors and their receptors in acute leukemia显示文摘 | Lowenberg B Touv IT | 1993 | Blood1993，81，2： | 1 |
| 10 | Cell attachment of human gingival fibriblasts in vitro to porous-surfaced titanium alloy discs coated with collagen and platelet-derived growth factor 显示文摘 | Lowenberg BF Pillar RM Aubin JE | 1988 | Biomaterials1988，9，4： | 1 |
| 11 | Phase 1/2 study to assess the safety, efficacy, and pharmacokinetics ofbarasertib(AZDll52) in patients with advanced acute myeloid leukemia显示文摘 | Lowenberg B Muus P Ossenkoppele G | 2011 | Blood2011，118，23： | 1 |
| 12 | Assessing English proficiency in the expanding circle 显示文摘 | Lowenberg P H | 2002 | World Englishes2002，，21： | 1 |
| 13 | Osteoclastic resorption of calcium phosphate ceramic thin films显示文摘 | Shapiro G Lowenberg B | 1993 | Cells Mater1993，3，3： | 1 |
| 14 | Insect immunity:isolation of three novel inducible antibacterial defensins from the vector mosquito, Aedes aegypti 显示文摘 | Bulet P Charier M | 1995 | Insect Biochem Mol Biol1995，25，7： | 1 |
| 15 | Thrombocytopenia in critically ill patients 显示文摘 | Levi M Lowenberg EC | 2008 | Seminars in Thrombosis & Hemostasis2008，34，5： | 1 |
| 16 | 显示文摘 | Comelissen J J Lowenberg B | 2000 | Curr Opin Hematol2000，7，6： | 1 |
| 17 | Clonogenic cells in acute myeloblastic leukemia显示文摘 | Griffin J Lowenberg B | 1986 | Blood1986，68，6： | 1 |
| 18 | Effect of priming with granulocyte colony-stimulating factor on the outcome of chemotherapy for acute myeloid leukemia显示文摘 | Lowenberg B van Putten W Theobald M | 2003 | N Engl J Med2003，349，8： | 1 |
| 19 | Migration, attachment, and orientation of human gingival fibroblasts to root slices, naked and porous-surfaced titianum alloy discs, and zircalloy 2discs in vitro显示文摘 | Lowenberg BF Pilliar RM Aubin JE | 1987 | J Dent1987，，5： | 1 |
| 20 | Relauon Between CXCR-4 Expression, Flt3 Mutations, and Unfavorable Progno?sis of Addt Acute Myeloid Leukemia显示文摘 | Rombouts EJ Pavic B Lowenberg B | 2004 | Blood2004，104，2： | 1 |
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