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| 1 | Metastatic pattern in esophageal and gastric cancer:Influenced by site and histology显示文摘BACKGROUND Detailed information on metastatic patterns in of patients with esophageal and gastric cancer is limited.Early recognition of metastases is important to avoid futile locoregional treatments.Furthermore,knowledge on metastatic patterns is necessary for further development of personalized treatment modalities.AIM To gain insight into the metastatic pattern of gastroesophageal cancer.METHODS A nationwide retrospective autopsy study of 3876 patients with adenocarcinoma(AC)or squamous cell carcinoma(SCC)of the esophagus or stomach between 1990 and 2017 was performed.Only patient with metastases were included for analysis.The metastatic pattern was analyzed according to the primary tumor location and histological subtype.RESULTS Metastatic disease was found in 268 esophageal and 331 gastric cancer patients.In esophageal cancer,the most common metastatic locations were liver(56%),distant lymph nodes(53%)and lung(50%).Esophageal AC showed more frequently metastases to the peritoneum and bone compared with esophageal SCC.In gastric cancer,the most common metastatic locations were distant lymph nodes(56%),liver(53%)and peritoneum(51%).Intestinal-type AC of the stomach showed metastases to the liver more frequently,whereas metastases to the bone,female reproductive organs and colorectum were observed more frequently in diffuse-type gastric AC.CONCLUSION This study showed differences in metastatic patterns of patients with esophageal and gastric cancer according to the primary tumor location and histological subtype. | Moniek HP Verstegen Mitchell Harker Carlijn van de Water Jolanda van Dieren Niek Hugen Iris D Nagtegaal Camiel Rosman Rachel S van der Post | 2020 | World Journal of Gastroenterology2020，26，39： | 9 |
| 2 | Causes and consequences of ischemic-type biliary lesions after liver transplantation显示文摘 | Carlijn I. Buis Harm Hoekstra Robert C. Verdonk Robert J. Porte | 2006 | Journal of Hepato - Biliary - Pancreatic Surgery2006，，6： | 2 |
| 3 | Anastomotic biliary strictures after liver transplantation: Causes and consequences显示文摘 | Robert C. Verdonk Carlijn I. Buis Robert J. Porte Eric J. van der Jagt Abraham J. Limburg Aad P. van den Berg Maarten J.H. Slooff Paul M.J.G. Peeters Koert P. de Jong Jan H. Kleibeuker Elizabeth B. Haagsma | 2006 | Liver Transpl2006，，5： | 2 |
| 4 | SDF-I induced actin polymeri- zation and migration in human hematopoietic progenitor cells 显示文摘 | Carlijn V Eloise CA Erik M | 2009 | Exp Hematol2009，29，： | 1 |
| 5 | Altered bile composition after liver transplantation is associated with the development of nonanastomotic biliary strictures显示文摘 | Carlijn I. Buis Erwin Geuken Dorien S. Visser Folkert Kuipers Elizabeth B. Haagsma Henkjan J. Verkade Robert J. Porte | 2008 | Journal of Hepatology2008，，1： | 1 |
| 6 | Biliary complications after liver transplantation: A review显示文摘 | Robert C. Verdonk Carlijn I. Buis Robert J. Porte Elizabeth B. Haagsma | 2006 | Scandinavian Journal of Gastroenterology (S)2006，，243： | 1 |
| 7 | Acute confusional state following liver transplantation for alcoholic liver disease显示文摘 | Carlijn I. Buis Russel H. Wiesner Ruud A.F. Krom Walter K. Kremers Eelco F.M. Wijdicks | 2002 | Neurology2002，，4： | 1 |
| 8 | A proinflammatory monocyte response is associated with myocardial injury and impaired functional outcome in patients with ST-segment elevation myocardial infarction显示文摘 | Anja M. van der Laan Alexander Hirsch Lourens F.H.J. Robbers Robin Nijveldt Ingrid Lommerse Ronak Delewi Pieter A. van der Vleuten Bart J. Biemond Jaap Jan Zwaginga Wim J. van der Giessen Felix Zijlstra Albert C. van Rossum Carlijn Voermans C. Ellen van d | 2012 | American Heart Journal2012，，1： | 1 |
| 9 | Acute confusional state following liver transplantation for alcoholic liver disease显示文摘 | Carlijn I. Buis Russel H. Wiesner Ruud A.F. Krom Walter K. Kremers Eelco F.M. Wijdicks | 2002 | Neurology2002，，4： | 1 |
| 10 | Serial magnetic resonance imaging of central pontine myelinolysis显示文摘 | Carlijn I. Buis Eelco F.M. Wijdicks | 2002 | Liver Transplantation2002，，7： | 1 |
| 11 | International codes of conduct and corporate social responsibility:can transnational corporations regulate themselves?显示文摘 | Ans Kolk Rob van Tulder Carlijn Welters | 1999 | Transnational Corporations1999，8，1： | 1 |
| 12 | A triaxial accelerometer and portable data processing unit for the assessment of daily physical activity显示文摘 | Carlijn V C Karel T M Maarten Vercluin | 1997 | IEEE Transactions on Biomedical Engineering1997，44，3： | 1 |
| 13 | Kiliaan, Fatty acids, lipid metabolism and Alzheimer pathology显示文摘 | Carlijn R Hooijmans Amanda J | 2008 | European Journal of Pharmacology2008，585，： | 1 |
| 14 | 活体生物荧光成像技术检测HO-1在HO-1/Luc小鼠肝脏缺血模型中的表达显示文摘目的尝试使用活体生物荧光成像技术无创定量检测HO-1在活体动物肝脏温缺血模型中的时空表达。方法建立小鼠部分肝脏温缺血模型,使用活体生物荧光成像技术连续检测HO-1在HO-1/Luc转基因报告小鼠中的转录情况。使用RT-PCR方法检测HO-1 mRNA水平,免疫组织化学方法行HO-1的表达定位。结果缺血肝叶发出的荧光信号最早于再灌注后3h被检测到,随后信号不断增强在9h达到峰值,然后信号逐渐减弱至再灌注后48h恢复至基础水平。RT-PCR方法测得在HO-1蛋白上调之前出现了HO-1mRNA的表达增强。免疫组织化学染色方法证实肝脏细胞是缺血再灌注损伤后HO-1表达上调的主要部位。结论活体生物荧光成像技术可以实时定量检测肝脏缺血后HO-1的表达,是一项敏感的检测技术。 | 宿华威 Carlijn I.Buis Robert J.Porter | 2007 | 中华肝胆外科杂志2007，13，3： | 1 |
| 15 | Pulmonary function and CT biomarkers as risk factors for cardiovascular events in male lung cancer screening participants: the NELSON study显示文摘 | Richard A. P. Takx Rozemarijn Vliegenthart Firdaus A. A. Mohamed Hoesein Ivana I?gum Harry J. Koning Willem P. Th. M. Mali Carlijn M. Aalst Pieter Zanen Jan-Willem J. Lammers Harry J. M. Groen Eva M. Rikxoort Michael Schmidt Bram Ginneken Matthijs Oudkerk | 2015 | European Radiology2015，，1： | 1 |
| 16 | Noninvasive metabolomic profiling as an adjunct to morphology for noninvasive embryo assessment in women undergoing single embryo transfer显示文摘 | Emre Seli Carlijn G. Vergouw Hiroshi Morita Lucy Botros Pieter Roos Cornelius B. Lambalk Naoki Yamashita Osamu Kato Denny Sakkas | 2010 | Fertility and Sterility2010，，2： | 1 |
| 17 | Phytoplankton biomass and pigment responses to Feamendments in the Pine Island and Amundsen polynyas显示文摘 | Matthew M Mills Anne Carlijn Alderkamp Charles Edouard Thuróczy | 2012 | Deep Sea Research Part Ⅱ:Topical Studies in Oceanography2012，，： | 1 |
| 18 | The etiology of pressure ulcers: Skin deep or muscle bound?显示文摘 | Carlijn V. Bouten Cees W. Oomens Frank P. Baaijens Daniel L. Bader | 2003 | Archives of Physical Medicine and Rehabilitation2003，，4： | 1 |
| 19 | Causes and consequences of ischemic-type biliary lesions after liver transplantation显示文摘 | Carlijn I. Buis Harm Hoekstra Robert C. Verdonk Robert J. Porte | 2006 | Journal of Hepato - Biliary - Pancreatic Surgery2006，，6： | 1 |
| 20 | Causes and consequences of ischemic - type biliary lesions after liver transplantation显示文摘 | Carlijn IB Harm H Robert CV | 2006 | J Hepatobiliary Pancreat Surg2006，13，6： | 1 |
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