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| 1 | Polymethylmethacrylate bone cements and additives: A review of the literature显示文摘Polymethylmethacrylate(PMMA) bone cement technology has progressed from industrial Plexiglass administration in the 1950 s to the recent advent of nanoparticle additives. Additives have been trialed to address problems with modern bone cements such as the loosening of prosthesis, high post-operative infection rates, and inflammatory reduction in interface integrity. This review aims to assess current additives used in PMMA bone cements and offer an insight regarding future directions for this biomaterial. Low index(< 15%) vitamin E and low index(< 5 g) antibiotic impregnated additives significantly address infection and inflammatory problems, with only modest reductions in mechanical strength. Chitosan(15% w/w PMMA) and silver(1% w/w PMMA) nanoparticles have strong antibacterial activity with no significant reduction in mechanical strength. Future work on PMMA bone cements should focus on trialing combinations of these additives as this may enhance favourable properties. | Manit Arora Edward KS Chan Sunil Gupta Ashish D Diwan | 2013 | World Journal of Orthopedics2013，4，2： | 10 |
| 2 | Systematic review of emergent laparoscopic colorectal surgery for benign and malignant disease显示文摘Laparoscopic surgery has become well established in the management of both and malignant colorectal disease.The last decade has seen increasing numbers of surgeons trained to a high standard in minimallyinvasive surgery.However there has not been the same enthusiasm for the use of laparoscopy in emergency colorectal surgery.There is a perception that emergent surgery is technically more difficult and may lead to worse outcomes.The present review aims to provide a comprehensive and critical appraisal of the available literature on the use of laparoscopic colorectal surgery(LCS)in the emergency setting.The literature is broadly divided by the underlying pathology;that is,inflammatory bowel disease,diverticulitis and malignant obstruction.There were no randomized trials and the majority of the studies were case-matched series or comparative studies.The overall trend was that LCS is associated with shorter hospital stay,par or fewer complications but an increased operating time.Emergency LCS can be safely undertaken for both benign and malignant disease providing there is appropriate patient selection,the surgeon is adequately experienced and there are sufficient resources to allow for a potentially more complex operation. | Manish Chand Muhammed RS Siddiqui Ashish Gupta Shahnawaz Rasheed Paris Tekkis Amjad Parvaiz Alex H Mirnezami Tahseen Qureshi | 2014 | World Journal of Gastroenterology2014，20，45： | 7 |
| 3 | Role of Joshi's external stabilization system with percutaneous screw fixation in high-energy tibial condylar fractures associated with severe soft tissue injuries显示文摘Purpose: The treatment of high-energy tibial condylar fractures which are associated with severe soft tissue injuries remains contentious and challenging. In this study, we assessed the results of Joshi's external stabilization system (JESS) by using the principle of ligamentotaxis and percutaneous screw fixation for managing high-energy tibial condylar fractures associated with severe soft tissue injuries. Methods: Between June 2008 and June 2010, 25 consecutive patients who were 17-71 years (mean, 39.7), underwent the JESS fixation for high-energy tibial condylar fractures associated with severe soft tissue injuries. Out of 25 patients, 2 were lost during follow-up and in 1 case early removal of frame was done, leaving 22 cases for final follow-up. Among them, 11 had poor skin condition with abrasions and blisters and 2 were open injuries (Gustilo-Anderson grade I & 11). The injury mechanisms were motor vehicle accidents (n - 19), fall from a height (n = 2) and assault (n - 1). The fractures were classified according to Schatzker classification system. Results: There were 7 type-V, 14 type-Vl and 1 type-IV Schatzker's tibial plateau fractures. The average interval between the injury and surgery was 6.8 days (range 2-13). The average hospital stay was 13 days (range, 7-22). The average interval between the surgery and full weight bearing was 13.6 weeks (range 11-20). The average range of knee flexion was 121° (range 105°-135°). The normal extension of the knee was observed in 20 patients, and an extensor lag of 5°-8° was noted in 2 patients. The complications included superficial pin tract infections (n 4) with no knee stiffness. Conclusion: JESS with lag screw fixation combines the benefit of traction, external fixation, and limited internal fixation, at the same time as allowing the ease of access to the soft tissue for wound checks, pin care, dressing changes, measurement of compartment pressure, and the monitoring of the neurovascular status. In a nutshell, JESS along with screw fixation offers a promising alternative treatment for high- energy tibial condylar fractures associated with severe soft tissue injuries. | Ashish Kumar Gupta Rahul Sapra Rakesh Kumar Som Prakash Gupta Devwart Kaushik Sahil Gaba Mahesh Chand Bansal Ratan Lal Dayma | 2015 | Chinese Journal of Traumatology2015，18，6： | 4 |
| 4 | Experience with hemoadsorption (CytoSorb~?) in the management of septic shock patients显示文摘BACKGROUND Cytokines and inflammatory mediators are the hallmarks of sepsis.Extracorporeal cytokine hemoadsorption devices are the newer clinical support system to overcome the cytokine storm during sepsis.AIM To retrospectively evaluate the clinical outcomes of patients admitted in intensive care unit with septic shock with different etiologies.METHODS The laboratory parameters including biomarkers such as procalcitonin,serum lactate and C-reactive protein;and the hemodynamic parameters;mean arterial pressure,vasopressor doses,sepsis scores,cytokine levels and other vital parameters were evaluated.We evaluated these outcomes among survivors and non-survivors.RESULTS Of 100 patients evaluated,40 patients survived.Post treatment,the vasopressors dosage remarkably decreased though it was not statistically different;34.15%(P=0.0816)for epinephrine,20.5%for norepinephrine(P=0.3099)and 51%(P=0.0678)for vasopressin.In the survivor group,a remarkable reduction of biomarkers levels;procalcitonin(65%,P=0.5859),C-reactive protein(27%,P=0.659),serum lactate(27%,P=0.0159)and bilirubin(43.11%;P=0.0565)were observed from baseline after CytoSorb^® therapy.A significant reduction in inflammatory markers;interleukin 6 and interleukin 10;(87%and 92%,P<0.0001)and in tumour necrosis factor(24%,P=0.0003)was also seen.Overall,28(28%)patients who were given CytoSorb^® therapy less than 48 h after onset of septic shock survived and the maximum duration of stay for 70%of these patients in intensive care unit was less than 15 d.CONCLUSION CytoSorb^® is a safe and well tolerated rescue therapy option in patients with septic shock.However,early(preferably within<48 h after onset of septic shock)initiation could result in better clinical outcomes.Further randomized trials are needed to define the potential benefits of this new treatment modality. | Yatin Mehta Chitra Mehta Ashish Kumar Joby Varghese George Aditi Gupta Saurabh Nanda Gourav Kochhar Arun Raizada | 2020 | World Journal of Critical Care Medicine2020，9，1： | 2 |
| 5 | Midodrine in patients with cirrhosis and refractory or recurrent ascites: A randomized pilot study显示文摘 | Virendra Singh Sahdeb P. Dhungana Baljinder Singh Rajesh Vijayverghia Chander K. Nain Navneet Sharma Ashish Bhalla Pramod K. Gupta | 2011 | Journal of Hepatology2011，，2： | 1 |
| 6 | Using partial information to update materialized view显示文摘 | Ashish Gupta Blackley J A | 1995 | Information System1995，20，8： | 1 |
| 7 | Synthesis and Characterization of Chemically Deposited Nanocrystalline CdSe Thin Film显示文摘 | AjayaKumar Singh SoumyaR. Deo GautamSheel Thool R.S. Singh Y.R. Katre Ashish Gupta | 2011 | Synthesis and Reactivity in Inorganic, Metal-Organic, and Nano-Metal Chemistry2011，，10： | 1 |
| 8 | Retroperitoneal Lymphangioma in an Adult: A Case Report of a Rare Clinical Entity显示文摘 | Mayank Tripathi Sanjeev Parshad Rajender Kumar Karwasra Ashish Gupta Saket Srivastva Ankush Sarwal Gabriel Sandblom | 2015 | Case Reports in Surgery2015，，： | 1 |
| 9 | Effects of the adjunctive probiotic VSL #3 on portal haemodynamics in patients with cirrhosis and large varices: a randomized trial显示文摘 | Nitin Gupta Ashish Kumar Praveen Sharma Vishal Garg Barjesh C. Sharma Shiv K. Sarin | 2013 | Liver Int2013，，8： | 1 |
| 10 | Lifi-light fidelity technology-A review显示文摘 | Kanchan Gupta Kajal Ashish Saini | 2014 | International Journal of Research2014，1，10： | 1 |
| 11 | Open-labeled study of unilateral autologous bone-marrow-derived mesenchymal stem cell transplantation in Parkinson’s disease显示文摘 | Neelam K. Venkataramana Satish K.V. Kumar Sudheer Balaraju Radhika Chemmangattu Radhakrishnan Abhilash Bansal Ashish Dixit Deepthi K. Rao Madhulita Das Majahar Jan Pawan Kumar Gupta Satish M. Totey | 2010 | Translational Research2010，，2： | 1 |
| 12 | Synergistic chemoprotective mechanisms of dietary phytoestrogens in a select combination against prostate cancer显示文摘 | Rajeev Kumar Vikas Verma Ashish Jain Rajeev K. Jain Jagdamba P. Maikhuri Gopal Gupta | 2011 | The Journal of Nutritional Biochemistry2011，，8： | 1 |
| 13 | PTEN -mediated AKT activation contributes to the reduced apoptosis among Indian oral squamous cell carcinoma patients显示文摘 | Nisreen Sherif Alyasiri Syed Jafar Mehdi M. Shabbir Alam Asgar Ali Ashish K. Mandal Sunita Gupta Ishwar Singh M. Moshahid Alam Rizvi | 2012 | Journal of Cancer Research and Clinical Oncology2012，，1： | 1 |
| 14 | Biaxial tensile behavior of spunbonded nonwovengeotextiles 显示文摘 | AMIT Rawal ADITYA Kochhar ASHISH Gupta | 2011 | Geotextiles and Geomembranes2011，29，： | 1 |
| 15 | Conserving biodiversity through traditional beliefs in sacred groves in Uttarakhand Himalaya, India显示文摘 | Ashish Anthwal Nutan Gupta Archana Sharma Smriti Anthwal KI-Hyun Kim | 2010 | Resources Conservation & Recycling2010，，11： | 1 |
| 16 | Effect of Cement Kiln Dust and Rock Dust as Mineral Fillers on Bulk Specific Gravity of Fine Aggregates显示文摘 | Gupta Ashish Zaman Musharraf Laguros Joakim Ghabchi Rouzbeh | 2011 | Journal of Testing and Evalu- ation2011，39，4： | 1 |
| 17 | Impaired monocyte‐macrophage functions and defective toll‐like receptor signaling in hepatitis E virus‐infected pregnant women with acute liver failure显示文摘 | Rashi Sehgal Sharda Patra Paul David Ashish Vyas Arshi Khanam Syed Hissar Ekta Gupta Guresh Kumar Shyam Kottilil Rakhi Maiwall Shiv Kumar Sarin Nirupama Trehanpati | 2015 | Hepatology2015，，6： | 1 |
| 18 | Open-labeled study of unilateral autologous bone-marrow-derived mesenchymal stem cell transplantation in Parkinson’s disease显示文摘 | Neelam K. Venkataramana Satish K.V. Kumar Sudheer Balaraju Radhika Chemmangattu Radhakrishnan Abhilash Bansal Ashish Dixit Deepthi K. Rao Madhulita Das Majahar Jan Pawan Kumar Gupta Satish M. Totey | 2010 | Translational Research2010，，2： | 1 |
| 19 | Maintaining views incrementally显示文摘 | Ashish Gupta Inderpal Singh Mumick V. S. Subrahmanian | 1993 | ACM SIGMOD Record1993，，2： | 1 |
| 20 | 1 H NMR-derived ser- um metabolomics of leukoplakia and squamous显示文摘 | Ashish Gupta Shalini Gupta Abbas All Mahdi | 2015 | Clin Chim Acta2015，441，2： | 1 |
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