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| 1 | 冠状动脉搭桥患者围术期血浆15-F_(2t)-isoprostane含量变化及临床意义显示文摘目的 分析常温心脏手术中血浆游离 15 F2 t isoprostane浓度变化及其与术后早期心功能的关系。方法 选择 30例在常温体外循环 (CPB)下行冠状动脉搭桥术患者 ,根据术后有 (组 )、无 (组 )应用正性肌力药物分为两组。 CPB中采用间断温血灌注 ,分别于麻醉诱导后、阻升主动脉后 30 min以及开放升主动脉后 10、30和 12 0 min抽取中心静脉血样 ,采用有高度特异性的兔血清抗体用酶标放射免疫法测量血浆中游离 15 F2 t isoprostane含量。术中至术后 6 h进行连续心排量测量。结果 15 F2 t isoprostane血浆含量于阻升主动脉后 30 m in、开放升主动脉后 10 min显著升高 ,开放升主动脉 30 m in以后开始下降。组 患者血浆 15F2 t isoprostane含量的升高呈递减趋势 ,至开放升主动脉后 30 min恢复正常 ;相反 ,术后需两种以上正性肌力药物支持以维持心脏指数 (CI) >2 .2 L· m in- 1· m- 2的患者 (组 )血浆 15 F2 t isoprostane含量至开放升主动脉后 30 m in均显著高于正常。术后 CI与开放升主动脉后 10和 30 min时血浆游离 15 F2 t isoprostane含量呈良好的负相关性 (r=- 0 .95 ,P<0 .0 1)。结论 术中 15 F2 t isoprostane血浆含量与术后心功能的恢复密切相关。 | 黄志勇 夏正远 David M. Ansley Baljinder | 2004 | 中国危重病急救医学2004，16，3： | 8 |
| 2 | Autologous bone marrow derived stem cell therapy in patients with type 2 diabetes mellitus-defining adequate administration methods显示文摘AIM To carry out randomized trial for evaluating effects of autologous bone marrow derived stem cell therapy(ABMSCT) through different routes.METHODS Bone marrow aspirate was taken from the iliac crest of patients. Bone marrow mononuclear cells were separatedand purified using centrifugation. These cells were then infused in a total of 21 patients comprising three groups of 7 patients each. Cells were infused into the superior pancreaticoduodenal artery(Group Ⅰ), splenic artery(Group Ⅱ) and through the peripheral intravenous route(Group Ⅲ). Another group of 7 patients acted as controls and a sham procedure was carried out on them(Group Ⅳ). The cells were labelled with the PET tracer F18-FDG to see their homing and in vivo distribution. Data for clinical outcome was expressed as mean ± SE. All other data was expressed as mean ± SD. Baseline and post treatment data was compared at the end of six months, using paired t-test. Cases and controls data were analyzed using independent t-test. A probability(P) value of < 0.05 was regarded as statistically significant. Measures of clinical outcome were taken as the change or improvement in the following parameters:(1) C-peptide assay;(2) HOMA-IR and HOMA-B;(3) reduction in Insulin dose; subjects who showed reduction of insulin requirement of more than 50% from baseline requirement were regarded as responders; and(4) reduction in HbA 1c. RESULTS All the patients, after being advised for healthy lifestyle changes, were evaluated at periodical intervals and at the end of 6 mo. The changes in body weight, body mass index, waist circumference and percentage of body fat in all groups were not significantly different at the end of this period. The results of intra-group comparison before and after ABMSCT at the end of six months duration was as follows:(1) the area under C-peptide response curve was increased at the end of 6 mo however the difference remained statistically non-significant(P values for fasting C-peptide were 0.973, 0.103, 0.263 and 0.287 respectively and the P values for stimulated C-peptide were 0.989, 0.395, 0.325 and 0.408 respectively for groups Ⅰ?to Ⅳ);(2) the Insulin sensitivity indices of HOMA IR and HOMA B also did not show any significant differences(P values for HOMA IR were 0.368, 0.223, 0.918 and 0.895 respectively and P values for HOMA B were 0.183, 0.664, 0.206 and 0.618 respectively for groups Ⅰto Ⅳ);(3) Group Ⅰshowed a significant reduction in Insulin dose requirement(P < 0.01). Group Ⅱ patients also achieved a significant reduction in Insulin dosages(P = 0.01). The Group Ⅰand Group Ⅱ patients together constituted the targeted group wherein the feeding arteries to pancreas were used for infusing stem cells. Group Ⅲ, which was the intravenous group, showed a non-significant reduction in Insulin dose requirement(P = 0.137). Group Ⅳ patients which comprised the control arm also showed a significant reduction in Insulin dosages at the end of six months(P < 0.05); and(4) there was a non-significant change in the Hb A1 c levels at the end of 6 mo across all groups(P = 0.355, P = 0.351, P = 0.999 and P = 0.408 respectively for groups Ⅰto Ⅳ). CONCLUSION Targeted route showed a significant reduction in Insulin requirement at the end of six months of study period whereas the intravenous group failed to show reduction. | Vikas Sood Anil Bhansali Bhagwant Rai Mittal Baljinder Singh Neelam Marwaha Ashish Jain Niranjan Khandelwal | 2017 | World Journal of Diabetes2017，8，7： | 6 |
| 3 | Microplastics in soil: Impacts and microbial diversity and degradation显示文摘Microplastics(MPs) are plastic particles less than 5 mm in size that have become a major environmental pollutant due to their ubiquitous and persistent nature. Microplastic contamination of the aquatic environment has received the most attention so far, whereas the current understanding of MP prevalence and its impacts in the terrestrial environment is largely limited. The MP contamination of soil can cause bioaccumulation and toxicity in terrestrial animals and plants, which can consequently affect human health. This review is aimed towards combining the available information on the occurrence, sources, and effects of MPs on the different aspects of the terrestrial environment and to highlight the limitations in our knowledge regarding the nature and impacts of MPs in soil. The review also highlights microbial degradation of MPs as an advancing research area, with numerous microorganisms being identified as capable of efficiently degrading this persistent contaminant. | Paramdeep KAUR Kashmir SINGH Baljinder SINGH | 2022 | Pedosphere2022，32，1： | 2 |
| 4 | GC/MS-based differential metabolic profiling of human peptic ulcer disease to study Helicobacter pylori-induced metabolic perturbations显示文摘Helicobacter pylori infection has been significantly linked to Peptic Ulcer Disease and Gastric Cancer.Metabolomic fingerprinting may offer a principal way of early diagnosis and to understand the molecular mechanism of H.pylori-induced pathogenicity.The rationale of the study is to explore the underlying distinct metabolic mechanisms of H.pylori-induced PUD and to identify potential biomarkers for disease diagnosis and associated risks using Gas chromatography/mass spectrometry.GC/MS-based analytical method was used to compare metabolic profiles of healthy controls(N=20)and peptic ulcer patients(N=45).Acquired metabolomic data were analyzed by constructing a diagnostic model using principal component analysis and a non-parametric two-tailed paired Wilcoxon analysis to identify disease-specific metabolic biomarkers.A total of 75 low-molecular-weight endogenous metabolites were detected during comparative metabolomic analysis of PUD vs.healthy gut tissues,among which 16 metabolites are being proposed to be diagnostic markers of Human PUD.Perturbations related to amino acids,carbohydrates,fatty acids,organic acids,and sterol metabolism were significantly revealed during this differential metabolomic profiling.Results convincingly suggest that metabolic profiles can contribute immensely in early diagnosis of the disease and understanding molecular mechanisms of disease progression for predicting novel drug targets for prophylactic and anaphylactic measures. | GAGANJOT GUPTA DEEPAK BANSAL ANSHULA SHARMA TAWSEEF AHMAD ATUL SACHDEV AJAZ AHMAD HAMED A.EL-SEREHY BALJINDER KAUR | 2021 | BIOCELL2021，45，5： | 2 |
| 5 | Noradrenaline vs. terlipressin in the treatment of hepatorenal syndrome: A randomized study显示文摘 | Virendra Singh Souvik Ghosh Baljinder Singh Pradeep Kumar Navneet Sharma Ashish Bhalla A.K. Sharma N.S. Choudhary Yogesh Chawla C.K. Nain | 2012 | Journal of Hepatology2012，，6： | 2 |
| 6 | Synthesis and characterization of a functional polyhedral oligomeric silsesquioxane and its flame retardancy in epoxy resin显示文摘 | Kun Wu Lei Song Yuan Hu Hongdian Lu Baljinder K. Kandola Everson Kandare | 2009 | Progress in Organic Coatings2009，，4： | 2 |
| 7 | Midodrine in patients with cirrhosis and refractory or recurrent ascites: A randomized pilot study显示文摘 | Virendra Singh Sahdeb P. Dhungana Baljinder Singh Rajesh Vijayverghia Chander K. Nain Navneet Sharma Ashish Bhalla Pramod K. Gupta | 2011 | Journal of Hepatology2011，，2： | 1 |
| 8 | Biomarkers for hepatocellular cancer显示文摘Hepatocellular carcinoma(HCC)is the third leading cause of cancer-related deaths worldwide.If diagnosed early,curative treatment options such as surgical resection,loco-regional therapies,and liver transplantation are available to patients,increasing their chances of survival and improving their quality of life.Unfortunately,most patients are diagnosed with late stage HCC where only palliative treatment is available.Therefore,biomarkers which could detect HCC early with a high degree of sensitivity and specificity,may play a crucial role in the diagnosis and management of the disease.This review will aim to provide an overview of the different biomarkers of HCC comprising those used in the diagnosis of HCC in at risk populations,as well as others with potential for prognosis,risk predisposition and prediction of response to therapeutic intervention. | Gurjot Singh Eric M Yoshida Sahaj Rathi Vladimir Marquez Peter Kim Siegfried R Erb Baljinder S Salh | 2020 | World Journal of Hepatology2020，12，9： | 1 |
| 9 | Noradrenaline vs terlipressin in the treatment of type 2 hepatorenal syndrome: a randomized pilot study显示文摘 | Saubhik Ghosh Narendra S. Choudhary Arun K. Sharma Baljinder Singh Pradeep Kumar Ritesh Agarwal Navneet Sharma Ashish Bhalla Yogesh K. Chawla Virendra Singh | 2013 | Liver Int2013，，8： | 1 |
| 10 | Thermal stability of phosphorylated cellulose modified with various transition metals显示文摘 | KAUR BALJINDER JAIN RAJESH K GUR I S | 1986 | Journal of Analytical and Applied Pyrolysis1986，9，： | 1 |
| 11 | Involvement of PPAR-gamma in curcumin-mediated beneficial effects in experimental dementia显示文摘 | Puneet Rinwa Baljinder Kaur Amteshwar Singh Jaggi Nirmal Singh | 2010 | Naunyn - Schmiedeberg’s Archives of Pharmacology2010，，6： | 1 |
| 12 | Synthesis and characterization of a functional polyhedral oligomeric silsesquioxane and its flame retardancy in epoxy resin显示文摘 | Kun Wu Lei Song Yuan Hu Hongdian Lu Baljinder K. Kandola Everson Kandare | 2009 | Progress in Organic Coatings2009，，4： | 1 |
| 13 | Complex Char Formation in Flame-retarded Fibre Intumescenl Combinations II Thermal Analytical Studies 显示文摘 | Baljinder K K Horrocks A R | 1996 | Polym I)egrad Stab1996，54，23： | 1 |
| 14 | 显示文摘 | Baljinder K K Bhaskar B Dennis P et aI | 2010 | Polym Degrad Stab2010，95，2： | 1 |
| 15 | Complex char formarion in flame retarded fibreintumescent combinations:Thermal analytical studies 显示文摘 | KANDOLA BALJINDER K RICHARD HORROCKS A | 1996 | Polymer Degradation and Stability1996，，54： | 1 |
| 16 | 18F-FDG PET-CT in evaluation of postoperative colorectal cancer patients with rising CEA level显示文摘 | Bhagwant Rai Mittal Raja Senthil Raghava Kashyap Anish Bhattacharya Baljinder Singh Rakesh Kapoor Rajesh Gupta | 2011 | Nuclear Medicine Communications2011，，9： | 1 |
| 17 | Complex char formation in flame-retarded fibre-intumescent combinations显示文摘 | BALJINDER K KANDOLA RICHARD HORROCKS A | 1996 | Polymer Degradation and Stability1996，54，： | 1 |
| 18 | Use and impact of electronic journals in the Indian Institute of Technology,Delhi,India显示文摘 | Baljinder K Verma R | | 0，，27： | 1 |
| 19 | Hypovitaminosis D in Adults with Inflammatory Bowel Disease: Potential Role of Ethnicity显示文摘 | Yi-Tzu Fu Nazira Chatur Cindy Cheong-Lee Baljinder Salh | 2012 | Digestive Diseases and Sciences2012，，8： | 1 |
| 20 | Current Clinical Therapies for Cartilage Repair, their Limitation and the Role of Stem Cells显示文摘 | Baljinder S Dhinsa Adetola B Adesida | 2012 | Current Stem Cell Research and Therapy2012，，2： | 1 |
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