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| 1 | Progress in carbon dioxide separation and capture: A review显示文摘这篇文章考察在 CO2 分离和俘获研究和工程取得的进步。各种各样的技术例如吸收,吸附,和膜分离,彻底地被讨论。象化学循环的燃烧和基于水合物的分离那样的新概念也简短被介绍。未来方向被建议。隐遁方法海洋授精和矿物质碳酸饱和技术例如造林,也被盖住。地下的注射和直接海洋垃圾场没被盖住。 | Hongqun Yang Zhenghe Xu Maohong Fan Rajender Gupta Rachid B Slimane Alan E Bland Ian Wright | 2008 | Journal of Environmental Sciences2008，20，1： | 89 |
| 2 | Phenotypic heterogeneity of mutations in androgen receptor gene显示文摘雄激素受体(AR ) 基因广泛地处于多样的临床的条件被学习了。除了点变化, trinucleotide 重复(CAG 和 GGN ) 长度多型性在遗传学者之中是兴趣和争吵的一个另外的题目。在三位字节重复的 Thepolymorphic 变化与很多混乱被联系了,但是同时矛盾的调查结果也被报导了。进一步,在不同人口的一样的混乱上的研究产生了不同结果。因此,联合了分析或出版研究的评论具有许多价值处于各种各样的临床的条件在基因在变化的意义上提取信息。AR 遗传广泛地被考察了,但是直到现在,评论文章集中于象 androgeninsensitivity 那样的单个临床的范畴,男不孕,前列腺癌症等等。我们作了第一个努力最考察 AR 遗传的方面。在各种各样的混乱的雄激素和在 AR 基因的多态的变化的影响是这评论的主要焦点。另外,在各种各样的研究观察的关联被讨论了根据在为在雄激素的行动以后的 AR 基因变化的效果可得到的 vitro 证据。 | Singh Rajender Lalji Singh Kumarasamy Thangaraj | 2007 | Asian Journal of Andrology2007，9，2： | 24 |
| 3 | 不同耕作和种植方式对稻田杂草及水稻产量的影响显示文摘采用田间试验,研究了7种不同水稻耕作和种植方式[水田翻耕移栽(puddling transplanting,PT)、免耕移栽(no tillage transplanting,NTT)、水田翻耕滚筒湿播(puddling drum wet seeding,PDWS)、免耕滚筒湿播(no tillage drum wet seeding,NTDWS)、传统耕作旱穴播(conventional tillage dry drilling,CTDD)、沟垄灌溉旱穴播(furrow irrigated raised beds system dry drilling,FIRBSDD)和免耕旱穴播(no-tillage dry-drilling,NTDD)对稻田杂草和水稻产量的影响。结果表明,PT处理下水稻产量最高,杂草干物质量最低;与移栽相比,直播(direct seeded rice,DSR),包括旱直播和湿直播,杂草生长能力最强,且不管有无杂草均降低了水稻产量;直播处理因杂草使水稻减产91.4%~99.0%,而PT和NTT处理分别减产16.0%和42.0%;香附子、龙爪茅、长穗苋、珠子草和假海马齿等杂草种类在DSR处理中大量出现,但在PT处理中未出现。大田示范试验结果表明,普通水稻品种(HKR-47和IR-64)在DSR处理较PT处理减产达15.8%,但优质水稻品种(Sharbati和PB-1)在两处理间无明显差异。当前劳动力紧缺,人工插秧需要大量劳力,因此亟需开发好氧栽培(如免耕直播和机插)模式下的适宜水稻品种及其相关配套农业机械及技术。 | Rajender Singh Chhokar 禹盛苗 | 2016 | 中国稻米2016，22，5： | 12 |
| 4 | Pooled genetic analysis in ultrasound measured non-alcoholic fatty liver disease in Indian subjects:A pilot study显示文摘AIM: To investigate genetic susceptibility in Indian subjects with non-alcoholic fatty liver disease(NAFLD) by performing a pooled genetic study.METHODS: Study subjects(n = 306) were recruited and categorized into NAFLD and control groups based on ultrasound findings of fatty infiltration. Of the 306 individuals, 156 individuals had fatty infiltration and thus comprised the NAFLD group. One hundred and fifty(n = 150) individuals were normal, without fatty infiltration of the liver, comprising the control group. Blood samples, demographic and anthropometric data from the individuals were collected after obtaining informed consent. Anthropometric data, blood glucose, lipids and liver function tests were estimated using standard methods. Genome wide association stud-ies done to date on NAFLD were identified, 19 single nucleotide polymorphisms(SNPs) were selected from these studies that were reported to be significantly associated with NAFLD and genotyping was performed on the Sequenom platform. Student's t test for continuous variables and χ2 test was applied to variant carriers from both groups. Required corrections were applied as multiple testing was done.RESULTS The mean age of the control group was 39.78 ± 10.83 and the NAFLD group was 36.63 ± 8.20 years. The waist circumference of males and females in the control and NAFLD groups were 80.13 ± 10.35; 81.77 ± 13.65 and 94.09 ± 10.53; 92.53 ± 8.27 respectively. The mean triglyceride and alanine transaminase(ALT) levels in the control and NAFLD groups were 135.18 ± 7.77; 25.39 ± 14.73 and 184.40 ± 84.31; 110.20 ± 67.05 respectively. When χ2 test was applied to the number of individuals carrying the variant risk alleles between the control and NAFLD group, a significant association was seen between rs738409 of the patatin-like phospholipase domain containing 3(PNPLA3) gene(P = 0.001), rs2073080 of the PARVB gene(P = 0.02), rs2143571 of SAMM50 gene(P = 0.05) and rs6487679 of the pregnancy zone protein(PZP) gene(P = 0.01) with the disease. Variant single nucleotide polymorphisms(SNPs) in NCAN and PNPLA3 gene were associated with higher levels of ALT, whereas variant SNPs in APOC3, PNPLA3, EFCAB4 B and COL13A1 were associated with high triglyceride levels. Apart from the above associations, rs2073080, rs343062 and rs6591182 were significantly associated with high BMI; rs2854117 and rs738409 with high triglyceride levels; and rs2073080, rs2143571, rs2228603, rs6487679 and rs738409 with high ALT levels.CONCLUSION: Pooled genetic analysis revealed an association of SNPs in PNPLA3, PARVB, SAMM50 and PZP genes with NAFLD. SNPs in NCAN and PNPLA3gene were associated with higher levels of ALT,whereas variant SNPs in APOC3, PNPLA3, EFCAB4 B and COL13A1 were associated with high triglyceride levels. | Vishnubhotla Venkata Ravi Kanth Mitnala Sasikala Padaki Nagaraja Rao Urmila Steffie Avanthi Kalashikam Rajender Rao Duvvuru Nageshwar Reddy | 2014 | World Journal of Hepatology2014，6，6： | 6 |
| 5 | Liver transplantation for metastatic neuroendocrine tumor: A case report and review of the literature显示文摘Neuroendocrine tumors are divided into gastrointestinal carcinoids and pancreatic neuroendocrine tumors. The WHO has updated the classification of these lesions and has abandoned the term 'carcinoid'. Both types of tumors are divided into functional and non-functional tumors. They are characterized by slow growth and frequent metastasis to the liver and may be limited to the liver for long periods. The therapeutic approach to hepatic metastases should consider the number and distribution of the liver metastases as well as the severity of symptoms related to hormone production and tumor bulk. Surgery is generally considered as the first line therapy. In patients with unresectable liver metastases,alternative treatments are dependent on the type and the growth rate. Initial treatments consist of long acting somatostatin analogs and/or interferon. Streptozocinbased chemotherapy is usually reserved for symptomatic patients with rapidly advancing disease, but generally the therapy is poorly tolerated and its effects are short-lived.Locoregional therapy directed such as hepatic-artery embolization and chemoembolization, radiofrequency thermal ablation and cryosurgery, is often used instead of systemic therapy, if the disease is limited to the liver.However, liver transplantation should be considered in patients with neuroendocrine metastases to the liver that are not accessible to curative or cytoreductive surgery and if medical or locoregional treatment has failed and if there are life threatening hormonal symptoms. We report a case of liver transplantation for metastatic neuroendocrine tumor of unknown primary source and provide a detailed review of the world literature on this controversial topic. | Wojciech C Blonski K Rajender Reddy Abraham Shaked Evan Siegelman David C Metz | 2005 | World Journal of Gastroenterology2005，11，48： | 5 |
| 6 | Immune Dysfunction and Infections in Patients With Cirrhosis显示文摘 | Alexander R. Bonnel Chalermrat Bunchorntavakul K. Rajender Reddy | 2011 | Clinical Gastroenterology and Hepatology2011，，9： | 4 |
| 7 | Diagnosis and Treatment of Hepatocellular Carcinoma显示文摘 | Hashem B. El-Serag Jorge A. Marrero Lenhard Rudolph K. Rajender Reddy | 2008 | Gastroenterology2008，，6： | 4 |
| 8 | American Gastroenterological Association Institute Guideline on the Prevention and Treatment of Hepatitis B Virus Reactivation During Immunosuppressive Drug Therapy显示文摘 | K. Rajender Reddy Kimberly L. Beavers Sarah P. Hammond Joseph K. Lim Yngve T. Falck-Ytter | 2015 | Gastroenterology2015，，1： | 3 |
| 9 | α-Fetoprotein, Des-γ Carboxyprothrombin, and Lectin-Bound α-Fetoprotein in Early Hepatocellular Carcinoma显示文摘 | Jorge A. Marrero Ziding Feng Yinghui Wang Mindie H. Nguyen Alex S. Befeler Lewis R. Roberts K. Rajender Reddy Denise Harnois Josep M. Llovet Daniel Normolle Jackie Dalhgren David Chia Anna S. Lok Paul D. Wagner Sudhir Srivastava Myron Schwartz | 2009 | Gastroenterology2009，，1： | 3 |
| 10 | Budd-Chiari syndrome:A single-center experience显示文摘AIM:To investigate challenges,risk factors,prognostic indicators,and treatment outcomes associated with Budd-Chiari syndrome(BCS)at a tertiary care center.METHODS:A retrospective cohort study was conducted at the University of Pennsylvania in patients with a diagnosis of BCS or hepatic vein thrombosis.All patients receiving care at the University of Pennsylvania,and who had at least 2 clinical encounters in the University of Pennsylvania Health system from January1,2008 to September 10,2013 were eligible for study inclusion.Data were extracted from the electronic medical record of each patient,and recorded in a secure Research Electronic Data Capture database.Logistic regression analyses were applied to identify predictors of outcome of liver transplant(LT)or death.RESULTS:Between January 1,2008 and September10,2013,forty-seven patients were identified.Median age was 42.4 years.Thirty-one(66.0%)were women.A majority were Caucasian(68.1%).At diagnosis,43(91.5%)patients had ascites,27(57.4%)patients had a hematologic disorder associated with a hypercoagulable state and 26(55.3%)had cirrhosis.Forty(85.1%)patients were on anticoagulation(AC),30(63.8%)of whom were maintained on warfarin.Two patients(4.3%)underwent thrombolytic therapy.A transjugular intrahepatic portosystemic shunt(TIPS)was placed in21(44.7%)patients,19(90.5%)of whom were also on AC.Twenty-one(44.7%)received AC alone.Over a median of 974 d,8(17.0%)patients received LT,and10(21.3%)died.The median time from listing to death was 26 mo[interquartile range(IQR)=16,65)].TIPS with AC was utilized more frequently in younger patients(P=0.02).Age,cirrhosis and chronic kidney disease(CKD)were significant predictors of LT or death.CONCLUSION:AC alone was employed as frequently as TIPS with AC,though the latter was used more frequently in younger patients with polycythemia vera.There were no significant differences in treatment outcome regardless of the therapeutic intervention employed.Significant predictors of poor prognosis included age,cirrhosis and CKD. | Tanya M Pavri Alan Herbst Rajender Reddy Kimberly A Forde | 2014 | World Journal of Gastroenterology2014，20，43： | 2 |
| 11 | Prevascularized Micro‑/Nano‑Sized Spheroid/Bead Aggregates for Vascular Tissue Engineering显示文摘Efficient strategies to promote microvascularization in vascular tissue engineering,a central priority in regenerative medicine,are still scarce;nano-and micro-sized aggregates and spheres or beads harboring primitive microvascular beds are promising methods in vascular tissue engineering.Capillaries are the smallest type and in numerous blood vessels,which are distributed densely in cardiovascular system.To mimic this microvascular network,specific cell components and proangiogenic factors are required.Herein,advanced biofabrication methods in microvascular engineering,including extrusion-based and droplet-based bioprinting,Kenzan,and biogripper approaches,are deliberated with emphasis on the newest works in prevascular nano-and micro-sized aggregates and microspheres/microbeads. | Maedeh Rahimnejad Narges Nasrollahi Boroujeni Sepideh Jahangiri Navid Rabiee Mohammad Rabiee Pooyan Makvandi Omid Akhavan Rajender S.Varma | 2021 | Nano-Micro Letters2021，13，11： | 2 |
| 12 | Hepatitis C virus therapy with peg-interferon and ribavirin in Myanmar: A resource-constrained country显示文摘AIM To investigate peg-interferon(peg-IFN) and ribavirin(RBV) therapy in Myanmar and to predict sustained virologic response(SVR).METHODS This single-center, open-label, study was conducted in Myanmar between 2009 and 2014. A total of 288 patients infected with HCV genotypes 1, 2, 3 and 6 were treated with peg-IFN alpha-2a(180 μg/wk) or alpha-2b(50 to 100 μg as a weight-based dose) and RBV as a weight-based dose(15 mg/kg/d). Treatment duration was 48 wk for genotypes 1 and 6, 24 wk for genotype 2, and 24 or 48 wk for genotype 3 based on rapid virologic response(RVR). Those co-infected with hepatitis B received 48 wk of therapy.RESULTS Overall, SVR was achieved for 82% of patients and the therapy was well tolerated. All patients achieved SVR at equivalent rates regardless of HCV genotype(P = 0.314). Low fibrosis scores(P < 0.001), high baseline albumin levels(P = 0.028) and low baseline viral loads(P = 0.029) all independently predicted SVR. On the other hand, IL-28 B TT and CC genotypes were not found to significantly predict SVR(P = 0.634; P = 0.618). Among those who completed treatment, the occurrence of RVR showed a > 96% positive predictive value for achieving SVR. Treatment duration did not significantly impact the likelihood of achieving SVR for patients infected with genotype 3 HCV(P = 0.371). The most common adverse events were fatigue(71%) and poor appetite(60%). Among patients with genotype 3 HCV, more patients in the 48-wk treatment group required erythropoietin than in the 24-wk treatment group(61.1% vs 49.2%).CONCLUSION SVR rates were high with peg-IFN and RBV therapy in Myanmar. Fibrosis scores, baseline albumin, HCV RNA levels and RVR independently predicted SVR. | Naomi Khaing Than Hlaing Debolina Banerjee Robert Mitrani Soe Htet Arker Kyaw San Win Nyan Lin Tun Zaw Thant Khin Maung Win K Rajender Reddy | 2016 | World Journal of Gastroenterology2016，22，43： | 2 |
| 13 | Silymarin Ascending Multiple Oral Dosing Phase I Study in Noncirrhotic Patients With Chronic Hepatitis C显示文摘 | Roy L. Hawke Sarah J. Schrieber Tedi A. Soule Zhiming Wen Philip C. Smith Rajender K. Reddy Abdus S. Wahed Steven H. Belle Nezam H. Afdhal Victor J. Navarro Josh Berman Qi-Ying Liu Edward Doo Michael W. Fried | 2010 | Journal of Clinical Pharmacology2010，，4： | 2 |
| 14 | Diagnosis and Treatment of Hepatocellular Carcinoma显示文摘 | Hashem B. El-Serag Jorge A. Marrero Lenhard Rudolph K. Rajender Reddy | 2008 | Gastroenterology2008，，6： | 2 |
| 15 | Androgen insensitivity syndrome: do trinucleotide repeats in androgen receptor gene have any role?显示文摘瞄准:为了调查 CAG 和 GGN 的角色,作为在敏感症候群(AIS ) 影响雄激素的基因背景重复显型。方法:我们分析了一些 -CAG 和 GGN 在 69 个 AIS 案例中重复的雄激素受体(AR ) ,与 136 个无关的正常男个人一起。重复的长度用扩大由突变而产生之遗传的 genotyping 跟随了决定等位基因长度的聚合酶链反应(PCR ) 被分析。结果:我们揭示的学习更突然显著地在病人意味着一些 CAG 重复(平均数 18.25 重复,范围 14-26 重复) 与控制相比(平均数 22.57 重复,范围 12-39 重复)( 二尾巴的 P <
0.0001 ) 。然而, GGN 重复没在病人(平均数 21.48 重复) 和控制(平均数 21.21 重复) 之间显著地不同(二尾巴的 P = 0.474 ) 。在病人的组之中, CAG 的吝啬的数字在敏感情况(平均数 15.83 重复) 中在部分雄激素重复显著地不到在里面在敏感情况(平均数 19.46 重复) 中的完全的雄激素(二尾巴的 P <
0.0001 ) 。结论:调查结果建议在 AR 基因的重复的更短的长度可能充当低外显率在在敏感改变雄激素的表明的基因背景。 | Singh Rajender Nalini J. Gupta Baidyanath Chakravarty Lalji Singh Kumarasamy Thangaraj | 2008 | Asian Journal of Andrology2008，10，4： | 2 |
| 16 | Acute-on-Chronic Liver Failure Before Liver Transplantation: Impact on Posttransplant Outcomes显示文摘 | Ranjeeta Bahirwani Oren Shaked Meenakshi Bewtra Kimberly Forde K. Rajender Reddy | 2011 | Transplantation2011，，8： | 2 |
| 17 | NS5A inhibitor, daclatasvir , for the treatment of chronic hepatitis C virus infection显示文摘 | D Alan Herbst K Rajender Reddy | 2013 | Expert Opinion on Investigational Drugs2013，，10： | 2 |
| 18 | 过渡金属电催化剂在硅基光阳极分解水产氧中的作用显示文摘光电化学分解水可将太阳能转换为绿色的氢能,为目前的能源危机和环境问题提供了一种理想的解决方案.在分解水反应中,涉及四空穴过程的产氧半反应是制约性能的关键步骤,往往需要在半导体表面沉积电催化剂以加速产氧反应动力学.因此,全面理解电催化剂在光电化学分解水体系中的作用至关重要.在目前的产氧电催化剂中,过渡金属羟基氧化物电催化剂(MOOH,M=Fe,Co,Ni)因其环保、廉价、高效以及稳定的特性,已被广泛用于半导体光阳极分解水器件中.而且,MOOH可用简单的电沉积方法沉积在光电极表面,易于大面积制备.然而,电沉积法制备的MOOH具有复杂的结构,对其作用机制的全面理解更加困难.因此,本文以电沉积MOOH修饰的硅基光阳极(n^(+)p-Si/SiO_(x)/Fe/FeOx/MOOH)作为模型,研究了不同电催化剂对硅光阳极光电化学产氧性能的影响.实验发现电催化剂的界面优化在电催化剂修饰的光电极中发挥着重要作用,这是因为优化的界面可以提升界面电荷传输,提供更多的催化反应活性位点以及更高的本征催化活性,从而更有利于光解水性能的提升.该项研究揭示了电催化剂在光解水器件中的作用,并为今后高效光解水器件的设计提供了一定指导.首先在多晶n^(+)p-Si基底上热蒸镀了一层30 nm的金属Fe膜,并通过电化学活化将Fe膜表面转换为FeOx得到Fe/FeOx(记作aFe)界面层,然后利用电沉积方法制备MOOH表面修饰层,最终得到n^(+)p-Si/SiO_(x)/aFe:MOOH光阳极.X射线光电子能谱、拉曼光谱以及扫描电子显微镜表面元素成像的表征结果均证实电极表面由于界面层金属Fe元素的掺杂而形成了Fe1-xNixOOH.在模拟太阳光下用于光解水产氧时,n^(+)p-Si/SiO_(x)/aFe:NiOOH电极的起始电位为~1.01 VRHE(相对于可逆氢电极的电势),在1.23 VRHE下的光电流为38.82 mA cm^(-2),显著优于n^(+)p-Si/SiO_(x)/aFe、n^(+)p-Si/SiO_(x)/aFe:FeOOH以及n^(+)p-Si/SiO_(x)/aFe:CoOOH三个对比样品,且其稳定性达到75 h.另外,我们发现n^(+)p-Si/SiO_(x)/aFe:MOOH电极的光电化学产氧性能均显著高于n^(+)p-Si/SiO_(x)/aFe电极,且p++-Si/SiO_(x)/aFe:MOOH的电催化产氧性能也高于p++-Si/SiO_(x)/MOOH,不仅证明了aFe界面层对Si与MOOH层之间的界面接触作用的有效调控,而且表明双电催化剂体系(aFe:MOOH)的电催化产氧活性高于单电催化剂(MOOH).热力学分析表明,n^(+)p-Si/SiO_(x)/aFe:MOOH光阳极的光电压大小与其光解水产氧性能并不一致,从而排除了热力学因素对性能的关键影响.进一步从塔菲尔斜率、电化学活性表面积和电化学阻抗谱对各电极的动力学进行了分析,证明了动力学因素在上述光阳极产氧性能中的主导作用.同时发现,由于aFe:NiOOH双电催化剂具有更高的本征电催化产氧性能,提供了更多的表面活性位点以及更有效地促进了光生载流子的传输,对动力学的提升效果更显著,从而使n^(+)p-Si/SiO_(x)/aFe:NiOOH光阳极表现出最高的光解水产氧性能. | Rajender Boddula 谢关才 郭北斗 宫建茹 | 2021 | Chinese Journal of Catalysis2021，42，8： | 2 |
| 19 | SRY-negative 46, XX male with normal genitals, complete masculinization and infertility显示文摘 | Rajender S Rajani V Gupta NJ | 2006 | Mol Hum Reprod2006，12，5： | 1 |
| 20 | Biosorption of chromium(Ⅵ)from aqueous and elcctroplating wasterwater using fungal biomass显示文摘 | Rajender Kumar Narsi R Bishnoi Garima Kiran Bishnoi | | 0，，03： | 1 |
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