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| 1 | The evolution and functional diversification of animal microRNA genes显示文摘microRNAs (miRNAs ) 是 22 核苷酸(nt ) 的一个丰富的班在更高真核细胞的染色体是弥漫的规章的 RNA。以便充分在染色体理解他们的突起,阐明是必要的能多样化 miRNA 活动的分子的机制。在这评论,我们描述一些允许新奇 miRNA 功能出现的许多策略,与 miRNA 基因怎么在动物演变的特别强调。这些机制在他们的顺序包括变化,处理,或表示模式;miRNA 的获得 * 功能或 antisense 处理;并且 de novo 基因出生。miRNAs 的设备和通用性位于下面多半演变并且变化他们怎么成为了更高的染色体的主导的成分。 | Na Liu Katsutomo Okamura David M Tyler Michael D Phillips Wei-Jen Chung Eric C Lai | 2008 | Cell Research2008，18，10： | 17 |
| 2 | Bile acids and sphingosine-1-phosphate receptor 2 in hepatic lipid metabolism显示文摘The liver is the central organ involved in lipid metabolism. Dyslipidemia and its related disorders, including non-alcoholic fatty liver disease(NAFLD), obesity and other metabolic diseases, are of increasing public health concern due to their increasing prevalence in the population. Besides their well-characterized functions in cholesterol homoeostasis and nutrient absorption, bile acids are also important metabolic regulators and function as signaling hormones by activating specific nuclear receptors, G-protein coupled receptors, and multiple signaling pathways. Recent studies identified a new signaling pathway by which conjugated bile acids(CBA) activate the extracellular regulated protein kinases(ERK1/2) and protein kinase B(AKT) signaling pathway via sphingosine-1-phosphate receptor 2(S1PR2). CBA-induced activation of S1PR2 is a key regulator of sphingosine kinase 2(Sph K2) andhepatic gene expression. This review focuses on recent findings related to the role of bile acids/S1PR2-mediated signaling pathways in regulating hepatic lipid metabolism. | Eric Kwong Yunzhou Li Phillip B.Hylemon Huiping Zhou | 2015 | Acta Pharmaceutica Sinica B2015，5，2： | 13 |
| 3 | Sofosbuvir and ledipasvir fixed-dose combination with and without ribavirin in treatment-naive and previously treated patients with genotype 1 hepatitis C virus infection (LONESTAR): an open-label, randomised, phase 2 trial显示文摘 | Eric Lawitz Fred F Poordad Phillip S Pang Robert H Hyland Xiao Ding Hongmei Mo William T Symonds John G McHutchison Fernando E Membreno | 2013 | The Lancet2013，，： | 5 |
| 4 | Whole Exome Sequencing to Identify a Novel Gene (Caveolin-1) Associated With Human Pulmonary Arterial Hypertension显示文摘 | Eric D. Austin Lijiang Ma Charles LeDuc Erika Berman Rosenzweig Alain Borczuk John A. Phillips Teresa Palomero Pavel Sumazin Hyunjae R. Kim Megha H. Talati James West James E. Loyd Wendy K. Chung | 2012 | Circulation: Cardiovascular Genetics2012，，3： | 2 |
| 5 | Detailed chemical kinetics model for supercritical ater oxidation of C1 compounds and H2显示文摘 | Eric E Brock Phillip E Savage | 1995 | AICHE Journal1995，41，8： | 1 |
| 6 | Biomechanical Analysis of Pin Placement for Pediatric Supracondylar Humerus Fractures: Does Starting Point, Pin Size, and Number Matter?显示文摘 | Hilton Phillip Gottschalk Daljeet Sagoo Diana Glaser Josh Doan Eric W. Edmonds John Schlechter | 2012 | Journal of Pediatric Orthopaedics2012，，5： | 1 |
| 7 | Germline PTEN Mutation Cowden Syndrome: An Under-Appreciated Form of Hereditary Kidney Cancer显示文摘 | Brian Shuch Christopher J. Ricketts Cathy D. Vocke Takefumi Komiya Lindsay A. Middelton Eric C. Kauffman Maria J. Merino Adam R. Metwalli Phillip Dennis W. Marston Linehan | 2013 | The Journal of Urology2013，，： | 1 |
| 8 | Effect of animal plasma proteins on intestinal damage and recovery of neonatal pigs infected with rotavirus显示文摘 | Benjamin A. Corl Robert J. Harrell Hong Kil Moon Oulayvahn Phillips Eric M. Weaver Joy M. Campbell John D. Arthington Jack Odle | 2007 | The Journal of Nutritional Biochemistry2007，，12： | 1 |
| 9 | 加快大型数据中心服务的可重构结构显示文摘数据中心的工作负载要求高计算能力、灵活性、能效和低成本。同时改善所有这些因素非常具有挑战性。为了推进数据中心超出商用服务器设计可以提供的能力,我们设计并构建了一个可组合、可重构的结构,来加速部分大型软件服务。结构的每个实例都由嵌入48台机器的半机架6×8二维环面高端Stratix V FPGA组成。每台服务器中都放置了一个FPGA,可以通过PCIe来访问,并用成对的10 Gb SAS电缆直接连接到其他FPGA。在本文中,我们描述了这种结构在1,632台服务器组(bed)的中等规模的部署,并测量了其在加快Bing搜索引擎方面的功效。我们描述了系统的要求和架构,详细介绍了关键技术挑战,以及使系统在出现故障情况下保持鲁棒性所需的解决方案,还有根据排名候选文档测量的系统性能、功率和弹性。在高负载时,一定范围内的可重构结构提高了每台服务器固定延迟分布的吞吐量排名95%——或在保持等效吞吐量时,减少29%的尾延迟。 | Andrew Putnam Adrian M.Caulfield Eric S.Chung Derek Chiou Kypros Constantinide John Demme Hadi Esmaeilzadeh Jeremy Fowers Gopi Prashanth Gopal Jan Gray Michael Haselman Scott Hauck Stephen Heil Amir Hormati Joo-Young Kim Sitaram Lanka James Larus Eric Peterson Simon Pope Aaron Smith Jason Thong Phillip Yi Xiao Doug Burger | 2015 | 中国集成电路2015，24，1： | 1 |
| 10 | Samarium — 153 EDTMP therapy of disseminated skeletal metastasis显示文摘 | J. Harvey Turner Andrew A. Martindale Peter Sorby Eric L. Hetherington Robert F. Fleay Ronald F. Hoffman Phillip G. Claringbold | 1989 | European Journal of Nuclear Medicine1989，，12： | 1 |
| 11 | Effect of animal plasma proteins on intestinal damage and recovery of neonatal pigs infected with rotavirus显示文摘 | Benjamin A. Corl Robert J. Harrell Hong Kil Moon Oulayvahn Phillips Eric M. Weaver Joy M. Campbell John D. Arthington Jack Odle | 2007 | The Journal of Nutritional Biochemistry2007，，12： | 1 |
| 12 | Association of antibody responses to microbial antigens and complications of small bowel Crohn’s disease显示文摘 | William S. Mow Eric A. Vasiliauskas Ying-Chao Lin Phillip R. Fleshner Konstantinos A. Papadakis Kent D. Taylor Carol J. Landers Maria T. Abreu-Martin Jerome I. Rotter Huiying Yang Stephan R. Targan | 2004 | Gastroenterology2004，，： | 1 |
| 13 | Oxytocin Increases Retention of Social Cognition in Autism显示文摘 | Eric Hollander Jennifer Bartz William Chaplin Ann Phillips Jennifer Sumner Latha Soorya Evdokia Anagnostou Stacey Wasserman | 2007 | Biological Psychiatry2007，，4： | 1 |
| 14 | Experimental and Computational Studies of Temperature Gradient-Driven Molecular Transport in Gas Flows Through Nano/Microscale Channels 显示文摘 | Yen-Lin Han Eric Phillip Muntz Alina Alexeenko | 2007 | Nanoscale and Microscale Thermophysical Engineering2007，11，： | 1 |
| 15 | A severity Rating Scale for Body Dysmorphic Disorder:Development, Reliability, and Validity of a Modified Version of the Yale--Brown Obsessive Compulsive Scale显示文摘 | Phillips Katharine A Eric Hollander | 1997 | Psychopharmacology Bulletin1997，33，1： | 1 |
| 16 | A reduced mechanism for methanol oxidation in supercritical water显示文摘 | Eric E Brock Phillip E Savage John R Barker | 1998 | Chem Eng Sci1998，53，5： | 1 |
| 17 | Analysis of acrylamide in food by GC/MS 显示文摘 | Trisa Robarge Eric Phillips Meredith Conoley | 2003 | The Application Notebook2003，9，： | 1 |
| 18 | Trends in cancer risk among people with AIDS in the United States 1980–2002显示文摘 | Eric A Engels Ruth M Pfeiffer James J Goedert Phillip Virgo Timothy S McNeel Steven M Scoppa Robert J Biggar | 2006 | AIDS2006，，12： | 1 |
| 19 | Effects of dexfenfluramine on aristolochic acid nephrotoxicity in a rat model for Chinese-herb nephropathy显示文摘 | Frédéric Debelle Jo?lle Nortier Volker M. Arlt Eric De Prez Anne Vienne Isabelle Salmon David H. Phillips Monique Deschodt-Lanckman Jean-Louis Vanherweghem | 2003 | Archives of Toxicology2003，，4： | 1 |
| 20 | Defining Sources of Coffee Plant Odor Attractive toCeratitis Capitata Flies显示文摘 | Ronald J. Prokopy Thomas W. Phillips Roger I. Vargas Eric B. Jang | 1997 | Journal of Chemical Ecology1997，，6： | 1 |
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