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| 1 | Potential cotton aphid, Aphis gossypii, population suppression by arthropod predators in upland cotton显示文摘棉花蚜虫,蚜虫属 gossypii 格洛弗,会聚的女士甲壳虫的 predation 率, Hippodamia convergens Guerin-Meneville,被在实验室随机把一个单个食肉动物分到每四个猎物密度处理决定。猎物密度包括了 25, 50, 100,和 200 蚜虫每 Petri 盘子竞技场。Predation 反应在把食肉动物分到他们的猎物处理以后在 1, 4, 8, 16, 24,和 48 h 被记录。整个时间增加的消费评价,与在实验的开始的 4 h 期间消费的所有 25 个蚜虫。在最高的密度,成年女士甲壳虫平均消费了 49, 99, 131, 163, 183,和 200 在 1, 4, 8, 16, 24 和 48 h 以内的蚜虫分别地。食肉动物显示了在关系的曲线的喂回答总计可得到的时间,显示会聚的女士甲壳虫有潜力压制通过由调整他们在喂期间的 predation 效率的连续的喂的蚜虫的更大的人口。在猎物的缺席的年龄特定的死亡的分析表明没有猎物,女士甲壳虫能为时间(超过 2 个星期) 的一个扩大时期幸存。一个食肉动物的能力推迟或阻止是在自然生物控制的一个重要因素的害虫人口的反弹没有猎物,幸存。 10 棉花节肢动物食肉动物种类的二年的地采样证明蜘蛛(27%)是在棉花由会聚的女士甲壳虫(23.5%)跟随了的得克萨斯高平原的最主导的叶子住所食肉动物, hooded 甲壳虫(13.5%),极小的海盗臭虫(11%),绿草蜻蛉(9.5%), bigeyed 臭虫(7.5%), scymnus 甲壳虫(3%),软翅膀的花甲壳虫(2%),年轻女人臭虫(1.5%),和暗杀者臭虫(1.5%)。地笼子研究显示出那一 H。每每叶在一个蚜虫的猎物密度释放的植物成年的 convergens 在经济阀值下面保留了蚜虫人口全部成长季节。 | Ram B. Shrestha Megha N. Parajulee | 2013 | Insect Science2013，20，6： | 10 |
| 2 | Dental implant treatment for renal failure patients on dialysis:a clinical guideline显示文摘Chronic kidney disease(CKD) is a worldwide public health problem that is growing in prevalence and is associated with severe complications. During the progression of the disease, a majority of CKD patients suffer oral complications. Dental implants are currently the most reliable and successful treatment for missing teeth. However, due to complications of CKD such as infections,bone lesions, bleeding risks, and altered drug metabolism, dental implant treatment for renal failure patients on dialysis is more challenging. In this review, we have summarized the characteristics of CKD and previous publications regarding dental treatments for renal failure patients. In addition, we discuss our recent research results and clinical experience in order to provide dental implant practitioners with a clinical guideline for dental implant treatment for renal failure patients undergoing hemodialysis. | Yuan,Quan Xiong,Qiu-Chan Gupta,Megha Maria Lopez-Pintor,Rosa Chen,Xiao-Lei Seriwatanachai,Dutmanee Densmore,Michael Man,Yi Gong,Ping | 2017 | International Journal of Oral Science2017，9，3： | 9 |
| 3 | Adaptive immune response during hepatitis C virus infection显示文摘Hepatitis C virus(HCV)infection affects about 170 million people worldwide and it is a major cause of liver cirrhosis and hepatocellular carcinoma.HCV is a hepatotropic non-cytopathic virus able to persist in a great percentage of infected hosts due to its ability to escape from the immune control.Liver damage and disease progression during HCV infection are driven by both viral and host factors.Specifically,adaptive immune response carries out an essential task in controllingnon-cytopathic viruses because of its ability to recognize infected cells and to destroy them by cytopathic mechanisms and to eliminate the virus by non-cytolytic machinery.HCV is able to impair this response by several means such as developing escape mutations in neutralizing antibodies and in T cell receptor viral epitope recognition sites and inducing HCV-specific cytotoxic T cell anergy and deletion.To impair HCV-specific T cell reactivity,HCV affects effector T cell regulation by modulating T helper and Treg response and by impairing the balance between positive and negative co-stimulatory molecules and between pro-and antiapoptotic proteins.In this review,the role of adaptive immune response in controlling HCV infection and the HCV mechanisms to evade this response are reviewed. | Juan Ramon Larrubia Elia Moreno-Cubero Megha Uttam Lokhande Silvia Garcia-Garzon Alicia Lazaro Joaquin Miquel Cristian Perna Eduardo Sanz-de-Villalobos | 2014 | World Journal of Gastroenterology2014，20，13： | 7 |
| 4 | Understanding the interaction of hepatitis C virus with host DEAD-box RNA helicases显示文摘The current therapeutic regimen to combat chronic hepatitis C is not optimal due to substantial side effects and the failure of a significant proportion of patients to achieve a sustained virological response.Recently developed direct-acting antivirals targeting hepatitis C virus(HCV)enzymes reportedly increase the virologic response to therapy but may lead to a selection of drug-resistant variants.Besides directacting antivirals,another promising class of HCV drugs in development include host targeting agents that are responsible for interfering with the host factors crucia for the viral life cycle.A family of host proteins known as DEAD-box RNA helicases,characterized by nine conserved motifs,is known to play an important role in RNA metabolism.Several members of this family such as DDX3,DDX5 and DDX6 have been shown to play a role in HCV replication and this review will summarize our current knowledge on their interaction with HCV.As chronic hepatitis C is one of the leading causes of hepatocellular carcinoma,the involvement of DEADbox RNA helicases in the development of HCC will also be highlighted.Continuing research on the interaction of host DEAD-box proteins with HCV and the contribution to viral replication and pathogenesis could be the panacea for the development of novel therapeutics against HCV. | Megha Haridas Upadya Jude Juventus Aweya Yee-Joo Tan | 2014 | World Journal of Gastroenterology2014，20，11： | 6 |
| 5 | Histological healing favors lower risk of colon carcinoma in extensive ulcerative colitis显示文摘AIM:To search for the answer in extensive ulcerative colitis as to whether histological inflammation persisting despite endoscopic mucosal healing serves to increase the risk of colon cancer(CC)or high grade dysplasia(HGD).METHODS:This is a single center(Lenox Hill Hospital)retrospective cohort and descriptive study of extensive ulcerative colitis(UC)for 20 years or more with a minimum of 3 surveillance colonoscopies and biopsies performed after the first 10 years of UC diagnosis.Data analyzed included:duration of UC,date of diagnosis of(CC)or(HGD),number of surveillance colonoscopies,and biopsies showing histological inflammation and its severity in each of 6 segments when endoscopic appearance is normal.Two subgroups of patients were compared:group 1 patients who developed CC/HGD and group 2 patients who did not develop CC/HGD.RESULTS:Of 115 patients with longstanding UC reviewed,68 patients met the inclusion criteria.Twenty patients were in group 1 and 48 in group 2.We identified the number of times for each patient when the endoscopic appearance was normal but biopsies nevertheless showed inflammation.Overall,histological disease activity in the absence of gross/endoscopic disease was found in 31.2%(95%CI:28%-35%)of colonoscopies performed on the entire cohort of 68 patients.Histological disease activity when the colonoscopy showed an absence of gross disease activity was more common in group 1 than group 2 patients,88%(95%CI:72%-97%)vs 59%(95%CI:53%-64%).Only 3/20(15%)of patients in group 1 ever had a colonoscopy completely without demonstrated disease activity(i.e.,no endoscopic or histological activity)as compared to 37/48(77%)of patients in group 2,and only 3.3%(95%CI:0.09%-8.3%)of colonoscopies in group 1 had no histological inflammation compared to23%(95%CI:20%-27%)in group 2.CONCLUSION:Progression to HGD or CC in extensive ulcerative colitis of long standing was more frequently encountered among those patients who demonstrate persistent histological inflammation in the absence of gross mucosal disease.Our findings support including the elimination of histological inflammation in the definition of mucosal healing,and support this endpoint as an appropriate goal of therapy because of its risk of increasing dysplasia and colon cancer. | Burton I Korelitz Keith Sultan Megha Kothari Leo Arapos Judy Schneider Georgia Panagopoulos | 2014 | World Journal of Gastroenterology2014，20，17： | 4 |
| 6 | Effects of seed mixture sowing with transgenic Bt rice and its parental line on the population dynamics of target stemborers and leafrollers, and non-target planthoppers显示文摘The widespread planting of insect-resistant crops has caused a dramatic shift in agricultural landscapes, thus raising concerns about the potential impacts on both target and non-target pests. In this study, we examined the potential effects of intra-specific seed mixture sowing with transgenic Bt rice (Bt) and its parental non-transgenic line (Nt)(100% Bt rice [Bt100], 5% Nt+95% Bt [Nt05Bt95], 10% Nt+90% Bt [Nt|0Bt90], 20% Nt+80% Bt [Nt2oBtso], 40% Nt+60% Bt [Nt4oBt6O] and 100% Nt rice [Ntjoo]) on target and non-target pests in a 2-year field trial in southern China. The occurrence of target pests, Sesamia inf evens. Chilo suppressalis and Cnaphalocrocis medinalis, decreased with the increased ratio of Bt rice, and the mixture ratios with more than 90% Bt rice (Btjoo and Nt()5Bt95) significantly increased the pest suppression efficiency, with the lowest occurrences of non-target planthoppers, Nilaparvata lugens and Sogatella jurcijera in Ntioo and NtosBtgs. Furthermore, there were no significant differences in 1000?grain dry weight and grain dry weight per 100 plants between Btjoo and NtosBtgs,Seed mixture sowing of Bt rice with <10%(especially 5%) of its parent line was sufficient to overcome potential compliance issues that exist with the use of block or structured refuge to provide most effective control of both target and non-target pests without compromising the grain yield. It is also expected that the strategy of seed mixture sowing with transgenic Bt rice and the nontransgenic parental line would provide rice yield stability while decreasing the insecticide use frequency in rice production. | Zhuo Li Li-Kun Li Bin Liu Long Wang Megha N. Parajulee Fa-Jun Chen | 2019 | Insect Science2019，26，4： | 4 |
| 7 | Effect of Low Level Subchronic Microwave Radiation on Rat Brain显示文摘Objective The present study was designed to investigate the effects of subchronic low level microwave radiation(MWR) on cognitive function,heat shock protein 70(HSP70) level and DNA damage in brain of Fischer rats.Methods Experiments were performed on male Fischer rats exposed to microwave radiation for 90 days at three different frequencies: 900,1800,and 2450 MHz.Animals were divided into 4 groups: Group I: Sham exposed,Group II: animals exposed to microwave radiation at 900 MHz and specific absorption rate(SAR) 5.953 × 10-4 W/kg,Group III: animals exposed to 1800 MHz at SAR 5.835 × 10-4 W/kg and Group IV: animals exposed to 2450 MHz at SAR 6.672 × 10-4 W/kg.All the animals were tested for cognitive function using elevated plus maze and Morris water maze at the end of the exposure period and subsequently sacrificed to collect brain tissues.HSP70 levels were estimated by ELISA and DNA damage was assessed using alkaline comet assay.Results Microwave exposure at 900-2450 MHz with SAR values as mentioned above lead to decline in cognitive function,increase in HSP70 level and DNA damage in brain.Conclusion The results of the present study suggest that low level microwave exposure at frequencies 900,1800,and 2450 MHz may lead to hazardous effects on brain. | Pravin Suryakantrao Deshmukh Kanu Megha Namita Nasare Basu Dev Banerjee Rafat Sultana Ahmed Mahesh Pandurang Abegaonkar Ashok Kumar Tripathi Pramod Kumari Mediratta | 2016 | Biomedical and Environmental Sciences2016，29，12： | 4 |
| 8 | Intercrop movement of convergent lady beetle, Hippodamia convergens (Coleoptera: Coccinellidae), between adjacent cotton and alfalfa显示文摘2 年的研究被进行描绘会聚的女士甲壳虫的 intercrop 运动, Hippodamia convergens Guerin-Meneville (翘目:Coccinellidae ) 在邻近的棉花和苜蓿之间。一个双标记蛋白质的方法被用来在每庄稼估计女士甲壳虫的 intercrop 运动。收集的 In turns 地在每庄稼的女士甲壳虫是由蛋白质的 assayed 确定的特定的 ELISA 在庄稼之间的甲壳虫的运动。结果显示会聚的女士甲壳虫的一个高百分比在棉花抓住了(46% 在 2008;56% 在 2009 ) 并且苜蓿(46% 在 2008;71% 在 2009 ) 包含了一个蛋白质标记,因此显示那个会聚的女士甲壳虫运动在邻近的庄稼之间大部分是双向的。尽管在一个低得多的比例,女士甲壳虫也从棉花显示出单向性的运动到苜蓿(5% 在 2008 和 6% 在 2009 ) 并且从苜蓿到棉花(9% 在 2008 和 14% 在 2009 ) 。甲壳虫展出的季节长的双向运动在学习的两年期间比棉花在苜蓿是显著地更高的。女士甲壳虫的全部的流入(双向、单向性联合) 在棉花与那相比在苜蓿是显著地更高的两年。当会聚的女士甲壳虫在邻近的棉花和苜蓿之间移动了时,他们是当棉花不是 flowering 时或当苜蓿为猎物提供了更多的机会时,吸引到苜蓿的更多。这研究提供很需要的信息在上杂种应该在利用保存的棉花便于综合害虫管理决定的会聚的女士甲壳虫的运动生物控制。 | Anup Bastola Megha N. Parajulee R. Patrick Porter Ram B. Shrestha Fa-Jun Chen Stanley C. Carroll | 2016 | Insect Science2016，23，1： | 4 |
| 9 | Relative preference of Lygus hesperus (Hemiptera: Miridae) to selected host plants in the field显示文摘 | Apurba K. Barman Megha N. Parajulee Stanley C. Carroll | 2010 | Insect Science2010，17，6： | 3 |
| 10 | Reliable cell purification and determination of cell purity:crucial aspects of olfactory ensheathing cell transplantation for spinal cord repair显示文摘Transplantation of olfactory ensheathing cells,the glia of the primary olfactory nervous system,has been trialed for spinal cord injury repair with promising but variable outcomes in animals and humans.Olfactory ensheathing cells can be harvested either from the lamina propria beneath the neuroepithelium in the nasal cavity,or from the olfactory bulb in the brain.As these areas contain several other cell types,isolating and purifying olfactory ensheathing cells is a critical part of the process.It is largely unknown how contaminating cells such as fibroblasts,other glial cell types and supporting cells affect olfactory ensheathing cell function post-transplantation;these cells may also cause unwanted side-effects.It is also,however,possible that the presence of some of the contaminant cells can improve outcomes.Here,we reviewed the last decade of olfactory ensheathing cell transplantation studies in rodents,with a focus on olfactory ensheathing cell purity.We analyzed how purification methods and resultant cell purity differed between olfactory mucosa-and olfactory bulb-derived cell preparations.We analyzed how the studies reported on olfactory ensheathing cell purity and which criteria were used to define cells as olfactory ensheathing cells.Finally,we analyzed the correlation between cell purity and transplantation outcomes.We found that olfactory bulb-derived olfactory ensheathing cell preparations are typically purer than mucosa-derived preparations.We concluded that there is an association between high olfactory ensheathing cell purity and favourable outcomes,but the lack of olfactory ensheathing cell-specific markers severely hampers the field. | Ronak Reshamwala Megha Shah Lucy Belt Jenny A.K.Ekberg James A.St John | 2020 | Neural Regeneration Research2020，15，11： | 3 |
| 11 | 表达阳春砂HMGR及DXR基因的转基因烟草的构建显示文摘【目的】3-羟基-3-甲基戊二酰辅酶A还原酶(3-hydroxy-3-methylglutaryl coenzyme A reductase,HMGR)和1-去氧-D-木酮糖-5-磷酸还原异构酶(1-deoxy-D-xylulose-5-phosphate reductoisomerase,DXR)是萜类生物合成途径的上游关键酶,构建表达阳春砂HMGR及DXR基因的转基因烟草,以期在模式植物中分析基因的生物学功能。【方法】采用亚克隆的方法构建AvHMGR和AvDXR的重组植物表达载体,电击转化农杆菌EHA105,获得带有目的基因的工程农杆菌;通过农杆菌介导的叶盘转化法转化烟草,筛选转基因植株;采用半定量逆转录—聚合酶链反应(RT-PCR)法分析目的基因在转基因烟草中的表达情况。【结果】构建了重组植物表达载体pBI-AvHMGR和pBI-AvDXR及其工程菌;对转基因烟草的PCR检测结果证实AvHMGR和AvDXR已整合到烟草基因组中;目的基因在部分转基因植株中得到表达。【结论】已构建成功表达阳春砂HMGR及DXR基因的转基因烟草。 | 杨锦芬 Megha Nath Adhikari 黄琼林 吴淑显 徐晖 陈蔚文 | 2011 | 广州中医药大学学报2011，28，3： | 3 |
| 12 | Phytopharmacological evaluation and anti-asthmatic activity of Ficus religiosa leaves显示文摘Objective:To discuss phytopharmacological potential and anti-asthmatic activity of Ficus religiosa(F.religiosa)(L.).Methods:Fresh leaves of F.religiosa were obtained from Vastrapur Lake,Ahmedabad,and dried to obtain powder.Histamine and acetylcholine were used to guinea pigs to establish bronchospasm model.In in vivo study,the aqueous extract of F.religiosa leaves (AEFR) at doses of 150 and 300 mg/ kg was administrated to guinea pigs,and the broncho-protective activity of AEFR was compared with aminophylline at 25 mg/kg.While in in vitro study,and 10 g/mL,20 g/mL,30 g/mL of AEFRL was administrated to guinea pigs,respectively, and mast cell stabilizing activity of AEFR was compared with ketotifen at 10 g/mL.Results: In the in-vivo model,pre-treatment with aminophylline(25 mg/kg,ip.) could significantly delay the onset of histamine induced pre-convulsive dyspnea,compared with vehicle control. Administration of AEFRL(150 and 300 mg/kg,ip.) also produced significant effect on latency to develop histamine & acetylcholine induced pre-convulsive dyspnea.In the mast cell stabilizing model,AEFRL at 10,20 and 30μg/mL could significantly increase the number of intact cells. Conclusions:It can be concluded that AEFRL is effective on histamine & acetylcholine induced bronchospasm in guinea pigs.In addition,AEFRL can potentiate the number of intact cells in the mast cell stabilizing model._____________________________________________________ | Megha Kapoor Nidhi Jasani Niyati Acharya Sanjeev Acharya Vimal Kumar | 2011 | Asian Pacific Journal of Tropical Medicine2011，4，8： | 3 |
| 13 | Sitagliptin,sitagliptin and metformin,or sitagliptin and amitriptyline attenuate streptozotocin-nicotinamide induced diabetic neuropathy in rats显示文摘Diabetic neuropathies are a family of nerve disorders caused by diabetes.Symptoms of the disease include nerve palsy,mononeuropathy,mononeuropathy multiplex,diabetic amyotrophy,painful polyneuropathy,autonomic neuropathy,and thoracoabdominal neuropathy.In this study,type 2 diabetes in rats was induced with nicotinamidestreptozotocin.Drug treatment was initiated on the d 15,with the combination regimen of metformin,pioglitazone and glimipiride or metformin and sitagliptin or sitagliptin,amitriptyline and sitagliptin and led to significantly improved glycemic control,increased grip strength and paw jumping response on d 21,28 and 35(P < 0.001).Significant increases in blood protein levels and decreases in urinary protein levels were observed in the animals treated with the different regimens on d 21,28 and 35(P < 0.001).Combined treatment of streptozotocin and nicotinamide caused marked degeneration of nerve cells,while administration of metformin and sitagliptin showed tissue regeneration and no body weight gain.In conclusion,treatment with sitagliptin and sitagliptin combined with metformin or amitriptyline results in no body weight gain,but causes an increase in grip strength and pain sensitivity,exhibits neural protection,and reverses the alteration of biochemical parameters in rats with streptozotocin-nicotinamide induced type 2 diabetes. | Ashish Kumar Sharma Akash Sharma Rita Kumari Kunal Kishore Divya Sharma Bharthu Parthsarthi Srinivasan Ashok Sharma Santosh Kumar Singh Samir Gaur Vijay Singh Jatav Prashant Sharma Varnika Srivastava Sneha Joshi Megha Joshi Prashant Kumar Dhakad Davender Singh Kanawat Akanksha Mishra Anil Sharma Dharmendra Singh Ravinder Pal Singh Himmat Singh Chawda Rambir Singh Sachin Kumar Raikwar Muneem Kumar Kurmi Pankaj Khatri Ashutosh Agarwal Arshee Munajjam | 2012 | The Journal of Biomedical Research2012，26，3： | 2 |
| 14 | Role of T cell death in maintaining immune tolerance during persistent viral hepatitis显示文摘Virus-specific T cells play an important role in the resolution of hepatic infection. However, during chronic hepatitis infection these cells lack their effector functions and fail to control the virus. Hepatitis B virus and hepatitis C virus have developed several mechanisms to generate immune tolerance. One of these strategies is the depletion of virus-specific T cells by apoptosis. The immunotolerogenic liver has unique property to retain and activate na ve T cell to avoid the over reactivation of immune response against antigens which is exploited by hepatotropic viruses to persist. The deletion of the virus-specific T cells occurs by intrinsic (passive) apoptotic mechanism. The pro-apoptotic molecule Bcl-2 interacting mediator (Bim) has attracted increasing attention as a pivotal involvement in apoptosis, as a regulator of tissue homeostasis and an enhancer for the viral persistence. Here, we reviewed our current knowledge on the evidence showing critical role of Bim in viral-specific T cell death by apoptotic pathways and helps in the immune tolerance. | Juan Ramón Larrubia Megha Uttam Lokhande Silvia García-Garzón Joaquín Miquel Dolores Subirá Eduardo Sanz-de-Villalobos | 2013 | World Journal of Gastroenterology2013，19，12： | 2 |
| 15 | Whole Exome Sequencing to Identify a Novel Gene (Caveolin-1) Associated With Human Pulmonary Arterial Hypertension显示文摘 | Eric D. Austin Lijiang Ma Charles LeDuc Erika Berman Rosenzweig Alain Borczuk John A. Phillips Teresa Palomero Pavel Sumazin Hyunjae R. Kim Megha H. Talati James West James E. Loyd Wendy K. Chung | 2012 | Circulation: Cardiovascular Genetics2012，，3： | 2 |
| 16 | Role of leptin and adiponectin in insulin resistance显示文摘 | Amita Yadav Megha A. Kataria Vandana Saini Anil Yadav | 2012 | Clinica Chimica Acta2012，，： | 2 |
| 17 | Vitamin E Supplementation Protects Oxidative Stress During Arsenic and Fluoride Antagonism in Male Mice显示文摘 | Megha Mittal S. J. S. Flora | 2007 | Drug and Chemical Toxicology2007，，： | 2 |
| 18 | AD和MCI患者梨状皮层功能连接破坏——初步分析显示文摘目的:阿尔茨海默病(Alzheimer’s disease,AD)和轻度认知障碍(mild cognitive impairment,MCI)均存在嗅觉障碍,此点已经由病理学研究结果所证实。探索AD和MCI患者的嗅觉网络改变,并假设与正常人对比,患者的网络连接减低。方法:我们搜集21例MCI和15例AD患者作为研究对象,全体被试均完成嗅觉功能磁共振成像(fMRI)及梨状皮层功能连接(functional connectivity,FC)分析。结果:与对照组相比,所有患者在双侧梨状皮层与其他嗅觉相关脑区的连接均减低(ANOVA,P<0.001)。结论:嗅觉网络与情感处理相关,嗅觉网络的连接中断,是造成AD和MCI患者左侧偏侧化功能障碍的潜在原因。本研究结果提示嗅觉系统可作为AD诊断性生物标志物,并为其常见并发症(包括冷漠和快感缺失)提供证据。 | Megha M.Vasavada 张汉 Robert McHugh 王建利 庞冉 Paul J.Eslinger Prasanna Karunanayaka 杨庆宪 | 2020 | 阿尔茨海默病及相关病杂志2020，3，1： | 2 |
| 19 | Testing the rate isomorphy hypothesis using five statistical methods显示文摘当发展阶段持续时间的比例由温度是未受影响的时,有机体被说在发展的率 isomorphy。全面阶段特定的发展数据在卷心菜甲壳虫上被产生, Colaphellus bowringi Baly (翘目:Chrysomelidae ) ,在在节肢动物上从水花的 16elative 影响的八温度,我们首先在喷洒前后在每个阴谋在丰富检验了吝啬的差别。所有草食动物在喷洒的阴谋在丰富减少了,但是在喷洒以后在控制阴谋增加了。大多数食肉动物(排除的 hemipterans ) 在控制阴谋显示出减少但是在喷洒的阴谋的按比例更大的减少。下次,我们检验了用 Abbott 的公式计算的改正的百分比人口减小。所有食肉动物(包括的 Araneae ) 经历了更大的减小(平均数 87%? 瑡愠祮搠獯 ? 戠瑵渠湯 ? 景琠敨漠桴牥猠数楣獥瀠潲畤散 ? 湡 ? 楬敶瀠潲敧祮愠 ?? 洠 ? | Xian-Ju Kuang Megha N.Parajulee Pei-Jian Shi Feng Ge Fang-Sen Xue | 2012 | Insect Science2012，19，1： | 2 |
| 20 | On the road to new treatments for multiple sclerosis: targeting dendritic cell migration into the central nervous system显示文摘Distinct migratory pathways and trafficking of dendritic cells to the central nervous system (CNS): The immune system is a host defense mechanism protecting against invaders, such as bacteria and viruses, while maintaining tolerance to self. Nonetheless, a few sites throughout the body are believed to be immunologically inert, such as the testes, the eye and the brain. Indeed, experiments in the mid-20th century gave rise to the concept of the brain as a site of immune privilege. Originally, the immune privilege of the brain was thought to be absolute, attributed by a physical blood-brain barrier (BBB) protecting the CNS from the entry of pathogens and circulating immune cells. These views have changed and currently, the CNS is seen as an immune-specialized site regulated by immunological components into and within the CNS. | Megha Meena Nathalie Cools | 2019 | Neural Regeneration Research2019，14，12： | 2 |
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