|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Nature:死亡的肿瘤细胞释放出胞内钾离子来阻断免疫系统显示文摘在一项新的研究中。来自美国国家癌症研究所和英国巴布拉汉研究所的研究人员发现当肿瘤组织死亡时从它当中泄露出来的一种无机离子起着阻止抗肿瘤免疫细胞发挥功能的作用。这一发现为开发调动免疫系统抵抗癌症的疗法提供一种新的方法。相关研究结果在线发表在Nature期刊上。 | Robert Eil, Suman K. Vodnala, David Clever, Christopher A. Klebanoff, Madhusudhanan Sukumar, Jenny H. Pan, Douglas C. Palmer, Alena Gros, Tori N. Yamamoto, Shashank J. Patel, Geoffrey C. Guittard, Zhiya Yu, David S. Schrump, W. Marston Linehan, Nicholas P. Restifo Christopher A. Klebanoff Valentina Carbonaro, Klaus Okkenhaug, Rahul Roychoudhuri | 2016 | 现代生物医学进展2016，16，31： | 12 |
| 2 | Decision support for integrated river basin management—Scientific research challenges显示文摘Integrated River Basin Management(IRBM)has been a long discussed way to sustainably manage water and land resources;yet,very few examples of effective IRBM are found because there is a lack of sufficient scientific support,as well as institutional accommodation,to successfully implement it.This paper overviews the major challenges with IRBM,the promising scientific approaches for the implementation of IRBM,and the areas of needed research,with considerable issues and experiences from China.It is expected that novel research will draw together disparate disciplines into an integrated scientific framework,upon which better modeling tools,stakeholder involvement,and decision-making support can be built.Cutting-edge new technologies will bring ideas of IRBM forward to theory and finally to practice.The paper will prompt scientists to undertake research to fill in the gaps in the current IRBM knowledge base and provide practitioners guidance on how to incorporate scientifically based information within the IRBM decision process. | CAI XiMing Landon MARSTON GE YingChun | 2015 | Science China Earth Sciences2015，58，1： | 7 |
| 3 | COVID-19 Mortality and Vaccine Coverage——Hong Kong Special Administrative Region,China,January 6,2022-March 21,2022显示文摘Summary What is already known about this topic?COVID-19 vaccines are important tools to protect populations from severe disease and death.What is added by this report?Among persons aged≥60 years in Hong Kong,49%,had received≥2 doses of a COVID-19 vaccine,and vaccination coverage declined with age.During January-March 2022,reported COVID-19-associated deaths rose rapidly in Hong Kong.Among these deaths,96%occurred in persons aged≥60 years;within this age group,the risk for death was 20 times lower among those who were fully vaccinated compared with those who were unvaccinated. | Dallas J.Smith Avi J.Hakim Gabriel M.Leung Wenbo Xu WWilliam Schluter Ryan T.Novak Barbara Marston Bradley S.Hersh | 2022 | China CDC weekly2022，4，14： | 6 |
| 4 | 整体固态生物转化后三七化学成分变化的初步研究显示文摘目的:通过研究曲霉菌在不同营养条件下对滇产三七进行固态生物转化后其皂苷部分的化学变化,寻找药理活性存在差异的原因。方法:采用含量测定、高效液相和液-质联用(LC-MS)技术,对三七不同转化条件所得产物的化学成分变化进行初步的研究分析。结果:含量测定表明,除1号样的R1有增加外,2个转化产物中的R1、Rg1、Re、Rb1都有所降低;在203.4nm和254.4nm波长下的HPLC图谱表明,原药材与2个转化产物的区别不仅表现在峰面积的改变上,而且有新吸收峰的出现;在LC-MS的检测中,2个转化产物中均未能检测出原药材中6个主要成分的色谱峰,但转化产物都出现了6个新的色谱峰,其中仅有1个相同。结论:三七经曲霉菌转化后总皂苷的化学成分发生了明显的变化,揭示了药理研究效果有差异的原因,同时也反映了微生物对转化底物的选择性受不同营养源的影响很大,这一新发现为采用固态生物转化法来进行天然药物的研究具有重要的指导意义。 | 马伟光 黄之镨 范培红 Andrew Marston Karine Ndjoko Ioset Kurt Hostettmann | 2010 | 中华中医药杂志2010，25，10： | 5 |
| 5 | Cloud computing — The business perspective显示文摘 | Sean Marston Zhi Li Subhajyoti Bandyopadhyay Juheng Zhang Anand Ghalsasi | 2010 | Decision Support Systems2010，，1： | 2 |
| 6 | The clinical implications of the genetics of renal cell carcinoma显示文摘 | Inger Rosner Gennady Bratslavsky Peter A. Pinto W. Marston Linehan | 2009 | Urologic Oncology: Seminars and Original Investigations2009，，2： | 2 |
| 7 | Powered Phlebectomy (TriVexTM) in Treatment of Varicose Veins显示文摘 | Nick Cheshire Steven M. Elias Blair Keagy R. Kolvenbach Austin L. Leahy W. Marston F. Pannier-Fischer Eberhard Rabe Gregory A. Spitz | 2002 | Annals of Vascular Surgery2002，，4： | 2 |
| 8 | Genetic diversity and temporal variation in the cyanophage community infecting marine Synechococcus species in Rhode island's coastal waters显示文摘 | Marston M F Sallee J L | 2003 | Applied and Environmental Microbiology2003，69，： | 1 |
| 9 | In vitro motility analysis of thin filaments from failing and non-failing human heart:troponin from failing human hearts induces slower filament sliding and higher Ca2+ sensitivity显示文摘 | Knott A Purcell I Marston S | 2002 | J Mol Cell Cardiol2002，34，4： | 1 |
| 10 | Provision of cobalt to ruminants by means of heavy pellets显示文摘 | DEWEY D LEE H J MARSTON H R | 1958 | Nature1958，181，4620： | 1 |
| 11 | Challenges in the Modelling of Scale Formation and Decarburisation of High Carbon, Special and General Steels显示文摘 | Marston H F Bolt PH Leprince G | 2004 | Ironmaking and Steelmaking2004，31，： | 1 |
| 12 | Natural histo- ry of limbs with arterial insufficiency and chronic ulcera- tion treated without revascularization显示文摘 | Marston WA Davies SW Armstrong B | 2006 | J Vasc Surg2006，，1： | 1 |
| 13 | Asenapine effects in animal models of psychosis and cognitive function显示文摘 | Marston HM Young JW Martin FD | 2009 | Psychopharmacology2009，206，4： | 1 |
| 14 | Prevalence of Bartonella henselae and Bartonella clarridgeiae in an ruban Indonesian cat population显示文摘 | Marston EL Finkel B Begnery RL | 1999 | Clinical and Diagnostic Laboratory Immunology1999，6，： | 1 |
| 15 | Xanthones from Polygala nyikensis显示文摘 | MARSTON A HAMBURGER M SORDAT D I | 1993 | Phytochemistry1993，33，4： | 1 |
| 16 | Effects of feed- ing energy or protein supplements before or after calving on per- fomlance of spring-calving cows grazing native range 显示文摘 | Marston T T Lusby K S Wettemann R P | 1995 | J Anita Sci1995，73，： | 1 |
| 17 | Distribution of tempo- ral spikes in relation to the sphenoidal electrode显示文摘 | Binnie C D Marston D Polkey CE | 1989 | Electroen- cephalogr Clin Neurophysiol1989，73，5： | 1 |
| 18 | The omega -3 polyunsat- urated fatty acid eicosapentaenoic acid inhibits mouse MC -26 color- ectal cancer cell liver metastasis via inhibition of PGE2 - dependent cell motility显示文摘 | Hawcroft G Volpato M Marston G | 2012 | Br J Pharmacol2012，166，： | 1 |
| 19 | Human geography without scale显示文摘 | Marston S A Jones J P Woodward K | 2005 | Transactions of the Institute of British Geographers2005，30，4： | 1 |
| 20 | Factors affecting vocabulary acquisition at age 2 in children born between 23 and 28 weeks' gestation显示文摘 | Marston L Peacock J Calvert S | 2007 | Dev Med Child Neurol2007，49，8： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员