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23篇 您的检索式:作者名="Nicholas Wilson"
    题名 作者 年代 出处 被引量
1The Mediterranean diet improves hepatic steatosis and insulin sensitivity in individuals with non-alcoholic fatty liver disease显示文摘Marno C. Ryan Catherine Itsiopoulos Tania Thodis Glenn Ward Nicholas Trost Sophie Hofferberth Kerin O’Dea Paul V. Desmond Nathan A. Johnson Andrew M. Wilson 2013Journal of Hepatology2013,,1:6
2UFMylation of RPL26 links translocation-associated quality control to endoplasmic reticulum protein homeostasis显示文摘Protein biogenesis at the endoplasmic reticulum(ER)in eukaryotic cells is monitored by a protein quality control system named ER-associated protein degradation(ERAD).While there has been substantial progress in understanding how ERAD eliminates defective polypeptides generated from erroneous folding,how cells remove nascent chains stalled in the translocon during co-translational protein insertion into the ER is unclear.Here we show that ribosome stalling during protein translocation induces the attachment of UFM1,a ubiquitin-like modifier,to two conserved lysine residues near the COOH-terminus of the 60S ribosomal subunit RPL26(uL24)at the ER.Strikingly,RPL26 UFMylation enables the degradation of stalled nascent chains,but unlike ERAD or previously established cytosolic ribosome-associated quality control(RQC),which uses proteasome to degrade their client proteins,ribosome UFMylation promotes the targeting of a translocation-arrested ER protein to lysosomes for degradation.RPL26 UFMylation is upregulated during erythroid differentiation to cope with increased secretory flow,and compromising UFMylation impairs protein secretion,and ultimately hemoglobin production.We propose that in metazoan,co-translational protein translocation into the ER is safeguarded by a UFMylation-dependent protein quality control mechanism,which when impaired causes anemia in mice and abnormal neuronal development in humans.Lihui Wang Yue Xu Heather Rogers Layla Saidi Constance Tom Noguchi Honglin Li Jonathan Wilson Yewdell Nicholas Raymond Guydosh Yihong Ye 2020Cell Research2020,30,1:5
3Pancreatic stents for prophylaxis against post-ERCP pancreatitis: a meta-analysis and systematic review显示文摘Abhishek Choudhary Matthew L. Bechtold Murtaza Arif Nicholas M. Szary Srinivas R. Puli Mohamed O. Othman Wilson P. Pais Mainor R. Antillon Praveen K. Roy 2011Gastrointestinal Endoscopy2011,,2:3
4Integrative Genomic Profiling of Human Prostate Cancer显示文摘Barry S. Taylor Nikolaus Schultz Haley Hieronymus Anuradha Gopalan Yonghong Xiao Brett S. Carver Vivek K. Arora Poorvi Kaushik Ethan Cerami Boris Reva Yevgeniy Antipin Nicholas Mitsiades Thomas Landers Igor Dolgalev John E. Major Manda Wilson Nicholas D. 2010Cancer Cell2010,,:2
5Interleukin-11 is the dominant IL-6 family cytokine during gastrointestinal tumorigenesis and can be targeted therapeutically显示文摘Tracy L. Putoczki Stefan Thiem Andrea Loving Rita A. Busuttil Nicholas J. Wilson Paul K. Ziegler Paul Nguyen Adele Preaudet Ryan Farid Kirsten Edwards Yeliz Boglev Rodney B. Luwor Andrew Jarnicki David Horst Alex Boussioutas Joan K. Heath Oliver M. Sieber 2013Cancer Cell2013,,:2
6Pancreatic stents for prophylaxis against post-ERCP pancreatitis: a meta-analysis and systematic review显示文摘Abhishek Choudhary Matthew L. Bechtold Murtaza Arif Nicholas M. Szary Srinivas R. Puli Mohamed O. Othman Wilson P. Pais Mainor R. Antillon Praveen K. Roy 2011Gastrointestinal Endoscopy2011,,2:1
7Proteomic analysis of macrophage differentiation显示文摘Xavier F Csar Nicholas J Wilson Kerrie-Ann McMahoni 2001The Journal of Biological Chemistry2001,276,26:1
8An empirical investigation of trade credit demand 显示文摘Summers Barbara Nicholas Wilson 2002International Journal of the Eco- nomics of Business2002,9,2:1
9Clinical, Endoscopic, and Histologic Findings Distinguish Eosinophilic Esophagitis From Gastroesophageal Reflux Disease显示文摘Evan S. Dellon Wood B. Gibbs Karen J. Fritchie Tara C. Rubinas Lindsay A. Wilson John T. Woosley Nicholas J. Shaheen 2009Clinical Gastroenterology and Hepatology2009,,12:1
10Effects of Wheel-rail Contact Geometry on Wheel Set Steering Forces显示文摘Stephen Mace Reuben Pena Nicholas Wilson 1996Wear1996,191,12:1
11Quit rates and the impact of participation, profit-sharing and unionization: Empirical evidence form UK engineering firras显示文摘Wilson Nicholas Cable John R and Peel Michael J 1990British Journal of Industrial Relations1990,28,2:1
12The effectiveness of a 17-week lifestyle intervention on health behaviors among airline pilots during COVID-19显示文摘Purpose:The aim of this study was to evaluate the efficacy of a 17-week,3-component lifestyle intervention for enhancing health behaviors during the coronavirus disease 2019(COVID-19)pandemic.Methods:A parallel-group(intervention and control)study was conducted amongst 79 airline pilots over a 17-week period during the COVID-19 pandemic.The intervention group(n=38)received a personalized sleep,dietary,and physical activity(PA)program.The control group(n=41)received no intervention.Outcome measures for sleep,fruit and vegetable intake,PA,and subjective health were measured though an online survey before and after the 17-week period.The changes in outcome measures were used to determine the efficacy of the intervention.Results:Significant main effects for time£group were found for International Physical Activity Questionnaire-walk(p=0.02)and for all other outcome measures(p<0.01).The intervention group significantly improved in sleep duration(p<0.01;d=1.35),Pittsburgh Sleep Quality Index score(p<0.01;d=1.14),moderate-to-vigorous PA(p<0.01;d=1.44),fruit and vegetable intake(p<0.01;d=2.09),Short Form 12v2 physical score(p<0.01;d=1.52),and Short Form 12v2 mental score(p<0.01;d=2.09).The control group showed significant negative change for sleep duration,Pittsburgh Sleep Quality Index score,and Short Form 12v2 mental score(p<0.01).Conclusion:Results provide preliminary evidence that a 3-component healthy sleep,eating,and PA intervention elicit improvements in health behaviors and perceived subjective health in pilots and may improve quality of life during an unprecedented global pandemic.Daniel Wilson Matthew Driller Ben Johnston Nicholas Gill 2021Journal of Sport and Health Science2021,10,3:1
13Understanding the Psychology of Possession and Ownership:A Personal Memoir and an Appraisal of Our Progress显示文摘Pendleton Andrew and Wilson Nicholas and Wright Mike 1998British Journal of Industrial Relations1998,36,1:1
14Integrative Genomic Profiling of Human Prostate Cancer显示文摘Barry S. Taylor Nikolaus Schultz Haley Hieronymus Anuradha Gopalan Yonghong Xiao Brett S. Carver Vivek K. Arora Poorvi Kaushik Ethan Cerami Boris Reva Yevgeniy Antipin Nicholas Mitsiades Thomas Landers Igor Dolgalev John E. Major Manda Wilson Nicholas D. 2010Cancer Cell2010,,1:1
15Effects of wheel-rail contact geometry on wheel set steering forces显示文摘STEPHEN MACE REUBEN PENA NICHOLAS WILSON 1996Wear1996,191,12:1
16Roles of the mitogen-activated protein kinase family in macrophage responses to colony stimulating factor-1 addition and withdrawal显示文摘Anthony J Nicholas J Wilson EC 0,,:1
17Valida- tion of Dynamic Rail Vehicle Models显示文摘Robert Fries Russell Walker Nicholas Wilson 2013Qingdao: IA- VSD 2013 Conference2013,,:1
18Pancreatic stents for prophylaxis against post-ERCP pancreatitis: a meta-analysis and systematic review显示文摘Abhishek Choudhary Matthew L. Bechtold Murtaza Arif Nicholas M. Szary Srinivas R. Puli Mohamed O. Othman Wilson P. Pais Mainor R. Antillon Praveen K. Roy 2011Gastrointestinal Endoscopy2011,,2:1
19Pooled Analysis of Clinical Outcomes with Neoadjuvant Cisplatin and Gemcitabine Chemotherapy for Muscle-Invasive Bladder Cancer显示文摘Bertram E. Yuh Nora Ruel Timothy G. Wilson Nicholas Vogelzang Sumanta K. Pal 2012The Journal of Urology2012,,:1
20Renal Transplantation: A Twenty-five Year Experience显示文摘JOSEPH E. MURRAY NICHOLAS L. TILNEY RICHARD E. WILSON 1976Annals of Surgery1976,,5:1
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