|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 人体动态稳定性理论及防跌倒扰动性训练进展显示文摘随着世界范围内老龄化社会问题的日益严重,以及一些有运动障碍的特殊群体的扩大,致使跌倒成为了一个严重的社会问题。人体动态稳定性理论是防跌倒研究的理论基础,目前已经取得了有价值的进展。人体动态稳定性理论不同于静态稳定性理论,后者给出的是人体质心位置与支撑面之间的相对位置关系,而前者增加了人体质心速度的因素,给出的是人体质心位置—速度状态与动态稳定区域之间的关系,可利用稳度来判定人体所处的稳定状态,甚至定量评价人体的动态稳定程度。影响跌倒的主要因素有二:稳度为负和支撑不力。在防跌倒的研究中进行适应性练习可显著地提高滑前稳度和滑后稳度,分别体现了前馈控制和反馈控制对人体动态稳定性的神经生理影响。 | 李世明 Yi-Chung Pai Feng Yang Tanvi Bhatt | 2011 | 体育科学2011，31，4： | 30 |
| 2 | 加拿大农业保险的经历和经验显示文摘加拿大从上个世纪初就有商业性保险公司试验经营农作物保险,但最后都失败了。后来,政府组织了准政策性农业保险,并在多年经验积累的基础上,于1960年开始举办政策性农业保险。46年来,加拿大特别是其曼尼托巴省的政策性农业保险取得了巨大成功,创造了丰富的经验,解决了一系列举办政策性农业保险所遇到的重要问题:根据实际情况确定由谁来经营政策性农业保险;如何合理确定必不可少的政府补贴和适当的保障水平;一下子铺开还是从少数几种农作物开始试验;到底是实行强制保险还是自愿保险更为合理和有效,要不要使具有不同风险损失概率的农户支付相同的保险费率;要不要组织省际之间的风险共担,是否需要对农民进行农业保险的培训;等等。 | Milton Boyd Jeffrey Pai 易细纯 张峭 | 2007 | 中国农村经济2007，，2： | 27 |
| 3 | Endoscopic ultrasound guided radiofrequency ablation,for pancreatic cystic neoplasms and neuroendocrine tumors显示文摘AIM: To outline the feasibility, safety, adverse events and early results of endoscopic ultrasound(EUS)-radiofrequency ablation(RFA) in pancreatic neoplasms using a novel probe. METHODS: This is a multi-center, pilot safety feasibility study. The intervention described was radiofrequency ablation(RF) which was applied with an innovative monopolar RF probe(1.2 mm Habib EUS-RFA catheter) placed through a 19 or 22 gauge fine needle aspiration(FNA) needle once FNA was performed in patients with a tumor in the head of the pancreas. The HabibTM EUSRFA is a 1 Fr wire(0.33 mm, 0.013') with a working length of 190 cm, which can be inserted through the biopsy channel of an echoendoscope. RF power is applied to the electrode at the end of the wire to coagulate tissue in the liver and pancreas.RESULTS: Eight patients [median age of 65(range 27-82) years; 7 female and 1 male] were recruited in a prospective multicenter trial. Six had a pancreatic cysticneoplasm(four a mucinous cyst, one had intraductal papillary mucinous neoplasm and one a microcystic adenoma) and two had a neuroendocrine tumors(NET) in the head of pancreas. The mean size of the cystic neoplasm and NET were 36.5 mm(SD ± 17.9 mm) and 27.5 mm(SD ± 17.7 mm) respectively. The EUSRFA was successfully completed in all cases. Among the 6 patients with a cystic neoplasm, post procedure imaging in 3-6 mo showed complete resolution of the cysts in 2 cases, whilst in three more there was a 48.4% reduction [mean pre RF 38.8 mm(SD ± 21.7 mm) vs mean post RF 20 mm(SD ± 17.1 mm)] in size. In regards to the NET patients, there was a change in vascularity and central necrosis after EUS-RFA. No major complications were observed within 48 h of the procedure. Two patients had mild abdominal pain that resolved within 3 d. CONCLUSION: EUS-RFA of pancreatic neoplasms with a novel monopolar RF probe was well tolerated in all cases. Our preliminary data suggest that the procedure is straightforward and safe. The response ranged from complete resolution to a 50% reduction in size. | Madhava Pai Nagy Habib Hakan Senturk Sundeep Lakhtakia Nageshwar Reddy Vito R Cicinnati Iyad Kaba Susanne Beckebaum Panagiotis Drymousis Michel Kahaleh William Brugge | 2015 | World Journal of Gastrointestinal Surgery2015，7，4： | 23 |
| 4 | Comparative clinical trial of S-pantoprazole versus racemic pantoprazole in the treatment of gastro-esophageal reflux disease显示文摘AIM: To compare the effi cacy and tolerability of S-pan- toprazole (20 mg once a day) versus racemic Panto- prazole (40 mg once a day) in the treatment of gastro- esophageal reflux disease (GERD). METHODS: This multi-centre, randomized, double-blind clinical trial consisted of 369 patients of either sex suf- fering from GERD. Patients were randomly assigned to receive either one tablet (20 mg) of S-pantoprazole once a day (test group) or 40 mg racemic pantoprazole once a day (reference group) for 28 d. Patients were evaluated for reduction in baseline on d 0, GERD symptom score on d 14 and 28, occurrence of any adverse effect during the course of therapy. Gastrointestinal (GI) endoscopy was performed in 54 patients enrolled at one of the study centers at baseline and on d 28. RESULTS: Signifi cant reduction in the scores (mean and median) for heart burn (P < 0.0001), acid regurgitation (P < 0.0001), bloating (P < 0.0001), nausea (P < 0.0001) and dysphagia (P < 0.001) was achieved in both groups on d 14 with further reduction on continuing the therapy till 28 d. There was a statistically signifi cant difference in the proportion of patients showing improvement in acid regurgitation and bloating on d 14 and 28 (P = 0.004 for acid regurgitation; P = 0.03 for bloating) and heart burn on d 28 (P = 0.01) between the two groups, with a higher proportion in the test group than in the refer- ence group. Absolute risk reductions for heartburn/acid regurgitation/bloating were approximately 15% on d 14 and 10% on d 28. The relative risk reductions were 26%-33% on d 14 and 15% on d 28. GI endoscopy showed no signifi cant difference in healing of esophagitis (P = 1) and gastric erosions (P = 0.27) between the two groups. None of the patients in either group reported any adverse effect during the course of therapy.CONCLUSION: In GERD, S-pantoprazole (20 mg) is more effective than racemic pantoprazole (40 mg) in improving symptoms of heartburn, acid regurgitation, bloating and equally effective in healing esophagitis and gastric erosions. The relative risk reduction is 15%-33%. Both drugs are safe and well tolerated. | Vikas G Pai Nitin V Pai Hemant P Thacker Jaisingh K Shinde Vijay P Mandora Subhash S Erram | 2006 | World Journal of Gastroenterology2006，12，37： | 19 |
| 5 | Smart manufacturing systems for Industry 4.0: Conceptual framework, scenarios, and future perspectives显示文摘 | Pai ZHENG Honghui WANG Zhiqian SANG Ray Y. ZHONG Yongkui LIU Chao LIU Khamdi MUBAROK Shiqiang YU Xun XU | 2018 | Frontiers of Mechanical Engineering2018，13，2： | 19 |
| 6 | Randomized, double-blind, comparative study of dexrabeprazole 10 mg versus rabeprazole 20 mg in the treatment of gastroesophageal reflux disease显示文摘AIM: To compare the efficacy and safety of dexrabe- prazole 10 mg versus rabeprazole 20 mg in the treatment of gastroesophageal reflux disease (GERD). METHODS: This was a randomized, double-blind clinical study. Fifty patients with GERD were randomly assigned to receive dexrabeprazole 10 mg or rabeprazole 20 mg once daily. Efficacy was assessed by evaluating improvement in visual analog scale (VAS) scores of heart-burn and regurgitation and safety was assessed by recording incidence of any adverse drug reactions. Laboratory investigations and upper gastro-intestinal endoscopy was conducted at baseline and after 28 d of therapy. RESULTS: A total of 50 patients (n = 25 in dexrabeprazole group and rabeprazole group each) completed the study. There were no significant differences in the baseline characteristics between the two groups. The VAS score (mean ± SD) of heartburn and regurgitation in dexrabeprazole (64.8 ± 5.1 and 64 ± 8.1, respectively) and rabeprazole (64.4 ± 8.7 and 57.6 ± 9.7, respectively) groups significantly reduced (P < 0.0001) to 30 ± 11.5, 24 ± 10 and 32 ± 9.5, 29.2 ± 11.9, respectively on d 28. A significantly higher (P = 0.002) proportion of patients showed ≥ 50% improvement in regurgitation with dexrabeprazole 10 mg (96%) compared to rabeprazole 20 mg (60%). Onset of symptom improvement was significantly earlier with dexrabeprazole than with rabeprazole (1.8 ± 0.8 d vs 2.6 ± 1.4 d; P <0.05). The incidences of esophagitis in the dexrabeprazole group and rabeprazole group before therapy were 84% and 92%, respectively (P = 0.38). The incidence of improvement/healing of esophagitis after therapy was more (P = 0.036) in the dexrabeprazole group (95.2%) compared to the rabeprazole group (65.2%). No adverse drug reaction was seen in either group.CONCLUSION: In the treatment of GERD, efficacy of dexrabeprazole 10 mg is better than rabeprazole 20 mg, with regards to improvement/healing of endoscopic lesions and relief from symptoms of regurgitation. | Vikas Pai Nitin Pai | 2007 | World Journal of Gastroenterology2007，13，30： | 18 |
| 7 | Cetuximab plus FOLFOX6 or FOLFIRI in metastatic colorectal cancer: CECOG trial显示文摘AIM: To investigate efficacy and safety of cetuximab combined with two chemotherapy regimens in patients with unresectable metastatic colorectal cancer (mCRC). METHODS: Randomized patients received cetuximab with 5-fluorouracil (5-FU), folinic acid (FA) and oxaliplatin (FOLFOX) 6 (arm A, n = 74) or 5-FU, FA and irinotecan (FOLFIRI) (arm B, n = 77). KRAS mutation status was determined retrospectively in a subset of tumors (n = 117). RESULTS: No significant difference was found between treatment arms A and B in the progression-free survival (PFS) rate at 9 mo, 45% vs 34%; median PFS, 8.6 mo vs 8.3 mo [hazard ratio (HR) = 1.06]; overall response rate (ORR) 43% vs 45% [odds ratio (OR) = 0.93] and median overall survival (OS), 17.4 mo vs 18.9 mo (HR = 0.98). Patients with KRAS wild-type tumors demonstrated improved PFS (HR = 0.55, P = 0.0051), OS, (HR = 0.62, P = 0.0296) and ORR (53% vs 36%) and in arm A, improved PFS (HR = 0.49, P = 0.0196), OS (HR = 0.48, P = 0.0201) and ORR (56%vs 30%), compared with patients with KRAS mutated tumors. In arm B no significant differences were found in efficacy by KRAS mutation status. Treatment in arms A and B was generally well tolerated. CONCLUSION: This study confirms that combinations of cetuximab with FOLFOX6 or FOLFIRI are effective and significantly improve clinical outcome in KRAS wild-type compared with KRAS mutated mCRC. | Janja Ocvirk Thomas Brodowicz Fritz Wrba Tudor E Ciuleanu Galina Kurteva Semir Beslija Ivan Koza Zsuzsanna Pápai Diethelm Messinger Ugur Yilmaz Zsolt Faluhelyi Suayib Yalcin Demetris Papamichael Miklós Wenczl Zrinka Mrsic-Krmpotic Einat Shacham-Shmueli Damir Vrbanec Regina Esser Werner Scheithauer Christoph C Zie-linski | 2010 | World Journal of Gastroenterology2010，16，25： | 17 |
| 8 | Metabolic syndrome and risk of subsequent colorectal cancer显示文摘The metabolic syndrome and visceral obesity have anincreasing prevalence and incidence in the generalpopulation. The actual prevalence of the metabolicsyndrome is 24% in US population and between24.6% and 30.9% in Europe. As demonstrated by many clinical trials (NAHANES , INTERHART) the metabolic syndrome is associated with an increased risk of both diabetes and cardiovascular disease. In addition to cardiovascular disease, individual components of the metabolic syndrome have been linked to the development of cancer, particularly to colorectal cancer. Colorectal cancer is an important public health problem; in the year 2000 there was an estimated total of 944 717 incident cases of colorectal cancer diagnosed world-wide. This association is sustained by many epidemiological studies. Recent reports suggest that individuals with metabolic syndrome have a higher risk of colon or rectal cancer. Moreover, the clusters of metabolic syndrome components increase the risk of associated cancer. The physiopathological mechanism that links metabolic syndrome and colorectal cancer is mostly related to abdominal obesity and insulin resistance. Population and experimental studies demonstrated that hyperinsulinemia, elevated C-peptide, elevated body mass index, high levels of insulin growth factor-1, low levels of insulin growth factor binding protein-3, high leptin levels and low adiponectin levels are all involved in carcinogenesis. Understanding the pathological mechanism that links metabolic syndrome and its components to carcinogenesis has a major clinical signifi cance and may have profound health benefi ts on a number of diseases including cancer, which represents a major cause of mortality and morbidity in our societies. | Raluca Pais Horatiu Silaghi Alina Cristina Silaghi Mihai Lucian Rusu Dan Lucian Dumitrascu | 2009 | World Journal of Gastroenterology2009，15，41： | 16 |
| 9 | Fast track anesthesia for liver transplantation: Review of the current practice显示文摘Historically,patients undergoing liver transplantation were left intubated and extubated in the intensive care unit(ICU)after a period of recovery.Proponents of this practice argued that these patients were critically ill andneed time to be properly optimized from a physiological and pain standpoint prior to extubation.Recently,there has been a growing movement toward early extubation in transplant centers worldwide.Initially fueled by research into early extubation following cardiac surgery,extubation in the operating room or soon after arrival to the ICU,has been shown to be safe with proper patient selection.Additionally,as experience at determining appropriate candidates has improved,some institutions have developed systems to allow select patients to bypass the ICU entirely and be admitted to the surgical ward after transplant.We discuss the history of early extubation and the arguments in favor and against fast track anesthesia.We also described our practice of fast track anesthesia at Mayo Clinic Florida,in which,we extubate approximately 60%of our patients in the operating room and send them to the surgical ward after a period of time in the post anesthesia recovery unit. | Stephen Aniskevich Sher-Lu Pai | 2015 | World Journal of Hepatology2015，7，20： | 13 |
| 10 | Cbl-b and PI3K/Akt pathway are differently involved in oxygen- glucose deprivation preconditioning in PC12 cells显示文摘 | Zhang Wei Yu Huan Zou Wei Wang Yan-fu Liang Xiao-feng Zhang Bo Kong Jing-jing Li Pai Zhang Duo-duo Yin Lin | 2013 | Chinese Medical Journal2013，，21： | 10 |
| 11 | Copy number variations are progressively associated with the pathogenesis of colorectal cancer in ulcerative colitis显示文摘AIM: To evaluate the association of known copy number variations(CNVs) in ulcerative colitis(UC) progressing to colorectal cancer.METHODS: Microsatellite instability analysis using the National Cancer Institute's panel of markers, and CNV association studies using Agilent 2 × 105 k arrays were done in tissue samples from four patient groups with UC: those at low risk(LR) or high risk of developing colorectal cancer, those with premalignant dysplastic lesions, and those with colitis-associated colorectal cancer(CAC). DNA from tissue samples of these groups were independently hybridized on arrays and analyzed. The data obtained were further subjected to downstream bioinformatics enrichment analysis to examine the correlation with CAC progression.RESULTS: Microarray analysis highlighted a progressive increase in the total number of CNVs [LR(n = 178) vs CAC(n = 958), 5.3-fold], gains and losses [LR(n = 37 and 141) vs CAC(n = 495 and 463), 13.4- and 3.3-fold, respectively], size [LR(964.2 kb) vs CAC(10540 kb), 10.9-fold] and the number of genes in such regions [LR(n = 119) vs CAC(n = 455), 3.8-fold]. Chromosomewise analysis of CNVs also showed an increase in the number of CNVs across each chromosome. There were 38 genes common to all four groups in the study; 13 of these were common to cancer genes from the Genetic Disease Association dataset. The gene set enrichment analysis and ontology analysis highlighted many cancerassociated genes. All the samples in the different groupswere microsatellite stable.CONCLUSION: Increasing numbers of CNVs are associated with the progression of UC to CAC, and warrant further detailed exploration. | Bhadravathi Marigowda Shivakumar Harish Rotti Thanvanthri Gururajan Vasudevan Aswath Balakrishnan Sanjiban Chakrabarty Ganesh Bhat Lakshmi Rao Cannanore Ganesh Pai Kapaettu Satyamoorthy | 2015 | World Journal of Gastroenterology2015，21，2： | 10 |
| 12 | 槲皮素结合Irinotecan或SN-38治疗或许对胃癌细胞的生长有抑制作用显示文摘目前尚无槲皮素结合irinotecan/SN-38治疗胃癌(GC)的研究报道。本文研究的目的是探讨槲皮素结合iri—notecan/SN-38能否更有效地降低癌细胞转移相关基因和蛋白质的表达,并减缓GC的发展。对象与方法:①体外研究。将经培养后的人类胃癌细胞(AGS)分别放入槲皮素(6.25,12.5,25,50,100μM)、SN-38(2.5,5,25,50,100nM)和槲皮素+SN-38中进行48h等处理后. | 张晗思 Lei CS Hou YC Pai MH | 2018 | 国际老年医学杂志2018，39，2： | 10 |
| 13 | Suppression of acute rejective response following orthotopic liver transplantation in experimental rats infected with Echinococcus multilocularis显示文摘背景肝的牙槽的包虫病(AE ) 是在人的寄生疾病并且由包虫 multilocularis (他们) 引起。Orthotopic 肝移植(OLT ) 可以是为结束阶段的唯一的有效治疗肝的 AE。在一些 AE 病人,然而, extrahepatic 他们不能完全在 OLT 以后被消除。我们试图学习他们避免引起的免疫学的变化是否可以影响 AE 的拒绝的 response.Methods 老鼠 modles 被以后把他们暂停注入布朗挪威( BN ) rats.Three 月的腹部建立,在试验性的组,肝从路易斯( LEW )老鼠被移植到感染他们的 BN rats.In 控制组,移植从 LEW 老鼠到健康 BN 老鼠。血(PB ) 取样的肝织物和外设在天被收集 1, 3, 5,和 7 在 OLT 以后。肝织物在染色的 hematoxylin 和曙红(H&E ) 以后被分析;外部血房间上的 CD4, CD8,和 CD28 的数字被流动 cytometry 检测;并且 chemokine fractalkine (Fkn ) 的表示被反向的抄写 PCR (RT-PCR ) 检测。Interleukin-10 (IL-10 ) 被连接酶的 immunosorbent 试金(ELISA ) 在浆液测量。在每个组,八只 BN 老鼠为观察到幸存在试验性的组接受者预定的幸存 time.Results 在控制组与那些相比被延长被保留。拒绝的反应以后发生了并且在试验性的组, CD4 的百分比, CD8, CD28 T 房间和 Fkn mRNA 是更温和的表示在试验性的组是更低的。当浆液 IL-10 层次比在控制 group.Conclusions 的那些在试验性的组是更高的时,在 OLT 以后的尖锐拒绝的反应与他们感染在老鼠被稀释,并且接受者幸存时间被延长。他们可以由提高 IL-10 分泌物在这个过程起一个作用,减少受动器 T 房间,禁止 Fkn 的表示,它导致还原剂煽动性的房间渗入进肝。 | LI Tao ZHAO Jin-ming ZHANG Yan PAI Zu-la ZHANG Wei Tuxun Tuer-hongjiang BAI Lei WU Jiang WEN Hao | 2011 | Chinese Medical Journal2011，，18： | 9 |
| 14 | Differentiation of Crohn’s disease from intestinal tuberculosis in India in 2010显示文摘Differentiating intestinal tuberculosis from Crohn’s disease (CD) is an important clinical challenge of considerable therapeutic significance. The problem is of greatest magnitude in countries where tuberculosis continues to be highly prevalent, and where the incidence of CD is increasing. The final clinical diagnosis is based on a combination of the clinical history with endoscopic studies, culture and polymerase chain reaction for Mycobacterium tuberculosis, biopsy pathology, radiological investigations and response to therapy. In a subset of patients, surgery is required and intraoperative findings with pathological study of the resected bowel provide a definitive diagnosis. Awareness of the parameters useful in distinguishing these two disorders in each of the different diagnostic modalities is crucial to accurate decision making. Newer techniques, such as capsule endoscopy, small bowel enteroscopy and immunological assays for Mycobacterium tuberculosis, have a role to play in the differentiation of intestinal tuberculosis and CD. This review presents currently available evidence regarding the usefulness and limitations of all these different modalities available for the evaluation of these two disorders. | Anna Benjamin Pulimood Deepak Narayan Amarapurkar Ujjala Ghoshal Mathew Phillip Cannanore Ganesh Pai Duvvur Nageshwar Reddy Birender Nagi Balakrishna Siddhartha Ramakrishna | 2011 | World Journal of Gastroenterology2011，17，4： | 8 |
| 15 | 精神发育迟滞的染色体微缺失研究显示文摘目的 探讨染色体微缺失在特发性精神发育迟滞 (mentalretardation ,MR)中的作用。方法应用荧光原位杂交 (fluorescenceinsituhybridization ,FISH )技术对 47例诊断不明的MR患儿进行染色体微缺失检测。结果 6例进行染色体间隙微缺失FISH分析的样本 ,检测到 7q11.2 3缺失 1例 ;46例进行染色体亚端粒FISH分析的样本 ,检测到 6q、2q亚端粒缺失各 1例。 结论 染色体微缺失为MR的重要病因 ,建议在常规染色体分析的基础上 ,对可疑间隙微缺失或亚端粒重组的患儿进行FISH分析。 | 李荣 赵正言 Shashidhar Pai | 2004 | 中华医学遗传学杂志2004，21，4： | 8 |
| 16 | Monocyte chemoattractant protein-1, transforming growth factor-β1, nerve growth factor, resistin and hyaluronic acid as serum markers:comparison between recurrent acute and chronic pancreatitis显示文摘BACKGROUND: Diagnostic parameters that can predict the presence of chronic pancreatitis(CP) in patients with recurrent pain due to pancreatitis would help to direct appropriate therapy. This study aimed to compare the serum levels of monocyte chemoattractant protein-1(MCP-1), transforming growth factor-β1(TGF-β1), nerve growth factor(NGF), resistin and hyaluronic acid(HA) in patients with recurrent acute pancreatitis(RAP) and CP to assess their ability to differentiate the two conditions.METHODS: Levels of serum markers assessed by enzymelinked immunosorbent assay(ELISA) were prospectively compared in consecutive patients with RAP, CP and in controls and stepwise discriminant analysis was performed to identify the markers differentiating RAP from CP.RESULTS: One hundred and thirteen consecutive patients(RAP=32, CP=81) and 78 healthy controls were prospectively enrolled. The mean(SD) age of the patients was 32.0(14.0)years; 89(78.8%) were male. All markers were significantly higher in CP patients than in the controls(P<0.001); MCP-1NGF and HA were significantly higher in RAP patients than in the controls(P<0.001). Stepwise discriminant analysis showed significant difference(P=0.002) between RAP and CP for resistin with an accuracy of 61.9%, discriminant scores of ≤-0.479 and ≥0.189 indicating RAP and CP, respectively. The other markers had no differential value between RAP and CP.CONCLUSION: Serum resistin is a promising marker to differentiate between RAP and CP and needs validation in future studies, especially in those with early CP. | M Ganesh Kamath C Ganesh Pai Asha Kamath Annamma Kurien | 2016 | Hepatobiliary & Pancreatic Diseases International2016，15，2： | 7 |
| 17 | Multipath effects on vector tracking algorithm for GNSS signal显示文摘The vector tracking algorithm uses a single extended Kalman filter(EKF) to predict the time-delays and the Doppler deviations of the GNSS signal, while also estimating the user's position, velocity, and clock state. In this paper, the effects of multipath on the tracking performance of the vector delay / frequency lock loop(VDFLL) is studied for better application in the multipath environment. The error expressions of the measurements are given in theory. The tracking error caused by multipath is reduced by VDFLL, which is proved by the tracking error of VDFLL through a new iterating method. The theoretical analysis is verified by the Monte Carlo simulation. | LUO Yu WANG YongQing WU SiLiang WANG Pai | 2014 | Science China(Information Sciences)2014，57，10： | 7 |
| 18 | Phylogenomics of polyploid Fothergilla (Hamamelidaceae) by RAD-tag based GBS insights into species origin and effects of software pipelines显示文摘 | Zhe-Chen Qi Yi Yu Xiang LiuI Andrew Pais Thomas Ranney Ross Whetten Qiu-Yun (Jenny) Xiang | 2015 | Journal of Systematics and Evolution2015，53，5： | 7 |
| 19 | No difference in mortality among ALPPS,two-staged hepatectomy,and portal vein embolization/ligation:A systematic review by updated traditional and network meta-analyses显示文摘Background:There is an ongoing debate on the feasibility,safety,and oncological efficacy of the associating liver partition and portal vein ligation for staged hepatectomy(ALPPS)technique.The aim of this study was to compare ALPPS,two-staged hepatectomy(TSH),and portal vein embolization(PVE)/ligation(PVL)using updated traditional meta-analysis and network meta-analysis(NMA).Data sources:Electronic databases were used in a systematic literature search.Updated traditional metaanalysis and NMA were performed and compared.Mortality and major morbidity were selected as primary outcomes.Results:Nineteen studies including 1200 patients were selected from the pool of 436 studies.Of these patients,315(31%)and 702(69%)underwent ALPPS and portal vein occlusion(PVO),respectively.Ninetyday mortality based on updated traditional meta-analysis,subgroup analysis of the randomized controlled trials(RCTs),and both Bayesian and frequentist NMA did not demonstrate significant differences between the ALPPS cohort and the PVE,PVL,and TSH cohorts.Moreover,analysis of RCTs did not demonstrate significant differences of major morbidity between the ALPPS and PVO cohorts.The ALPPS cohort demonstrated significantly more favorable outcomes in hypertrophy parameters,time to operation,definitive hepatectomy,and R0 margins rates compared with the PVO cohort.In contrast,1-year disease-free survival was significantly higher in the PVO cohort compared to the ALPPS cohort.Conclusions:This study is the first to use updated traditional meta-analysis and both Bayesian and frequentist NMA and demonstrated no significant differences in 90-day mortality between the ALPPS and other hepatic hypertrophy approaches.Furthermore,two high quality RCTs including 147 patients demonstrated no significant differences in major morbidity between the ALPPS and PVO cohorts. | Paschalis Gavriilidis Robert P Sutcliffe Keith J Roberts Madhava Pai Duncan Spalding Nagy Habib Long R Jiao Mikael H Sodergren | 2020 | Hepatobiliary & Pancreatic Diseases International2020，19，5： | 6 |
| 20 | Acupuncture Treatment for Idiopathic Trigeminal Neuralgia:A Longitudinal Case-Control Double Blinded Study显示文摘Objective: To evaluate the treatment effect of acupuncture on patients with idiopathic trigeminal neuralgia(ITN) by case-control longitudinal blinded study. Methods: Sixty ITN patients and 30 healthy subjects were included. The ITN patients were randomly assigned to acupuncture group(15 cases), sham-acupuncture group(15 cases) and carbamazepine group(30 cases), respectively. Clinical orofacial evaluation(including pain intensity and medication doses), research diagnostic criteria for temporomandibular disorders(RDC/TMD) and Helkimo indexes(for functional evaluation of the masticatory system), and quantitative sensory testing for sensory thresholds(gustative, olfactory, cold, warm, touch, vibration and superficial and deep pain) were evaluated before treatment, immediately after treatment, and 6 months after treatment. Results: The mean pain intensity by the Visual Analogue Scale only decreased in the acupuncture group at the last evaluation(P=0.012). Patients in the sham-acupuncture group had an increase in carbamazepine doses according to the prescriptions(P<0.01). There was a reduction in secondary myofascial pain and mandibular limitations at the acupuncture and sham-acupuncture groups, however only the acupuncture group kept the changes after 6 months(P<0.01, P=0.023). There was a decrease in mechanical thresholds in the acupuncture group(tactile, P<0.01; vibration, P=0.027) and an increase in deep pain thresholds in both acupuncture and sham-acupuncture groups(P=0.013). Conclusion: Acupuncture can be an option in the treatment of ITN due to its analgesic effect in both ITN and secondary myofascial pain associated with it. | Michelle Cristina Ichida Mariana Zemuner Jorge Hosomi Hong Jin Pai Manoel Jacobsen Teixeira JoséTadeu Tesseroli de Siqueira Silvia R D T de Siqueira | 2017 | Chinese Journal of Integrative Medicine2017，23，11： | 6 |
您所在的机构暂未开通此部分的功能，请联系管理员