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| 1 | 新诊断1型糖尿病患者胃固体食物排空功能观察显示文摘 | 冯波 Dan Ziegler | 2000 | 中华内分泌代谢杂志2000,16,5: | 9 |
| 2 | Nano-Morphology of a Polymer Electrolyte Fuel Cell Catalyst Layer Imaging, Reconstruction and Analysis显示文摘在聚合物电解质燃料房间(PEFC ) 的阴极催化剂层(CCL ) 的氧减小反应(ORR ) 在操作期间是表演损失的主要原因之一。另外, CCL 由于磅催化剂的使用是最昂贵的部件。除了 ORR 本身,种类运输到并且从反应地点决定 PEFC 的表演。在 CCL 的种类的有效运输性质取决于它的 nanostructure。因此, CCL 的三维的重建被要求。一系列二维的图象从集中的离子横梁扫描被获得为二维的图象的电子显微镜(FIB-SEM ) 成像和一个分割方法被开发了。毛孔尺寸分发(PSD ) 为三维的几何学被计算。PSD 上的排列和各向异性的象素尺寸的影响被调查了。毛孔在在 5 nm 和 205 nm 之间的范围被发现。Knudsen 数字的评估证明在 CCL 的那煤气的运输被转变流动政体管理。液体水运输能被包括在连续统水动力学以内描述合适滑动流动边界条件。 | Simon Thiele Roland Zengerle Christoph Ziegler | 2011 | Nano Research2011,4,9: | 5 |
| 3 | Estimation of sediment sources using selected chemical tracers in the Perry lake basin,Kansas,USA显示文摘The ability to achieve meaningful decreases in sediment loads to reservoirs requires a determination of the relative importance of sediment sources within the contributing basins. In an investigation of sources of fine-grained sediment(clay and silt) within the Perry Lake Basin in northeast Kansas,representative samples of channel-bank sources,surface-soil sources(cropland and grassland),and reservoir bottom sediment were collected,chemically analyzed,and compared. The samples were sieved to isolate the <63 μ m fraction and analyzed for selected nutrients(total nitrogen and total phosphorus),organic and total carbon,25 trace elements,and the radionuclide cesium-137(137Cs). On the basis of substantial and consistent compositional differences among the source types,total nitrogen(TN),total phosphorus(TP),total organic carbon(TOC),and 137Cs were selected for use in the estimation of sediment sources. To further account for differences in particle-size composition between the sources and the reservoir bottom sediment,constituent ratio and clay-normalization techniques were used. Computed ratios included TOC to TN,TOC to TP,and TN to TP. Constituent concentrations(TN,TP,TOC) and activities(137Cs) were normalized by dividing by the percentage of clay. Thus,the sediment-source estimations involved the use of seven sediment-source indicators. Within the Perry Lake Basin,the consensus of the seven indicators was that both channel-bank and surface-soil sources were important in the Atchison County Lake and Banner Creek Reservoir subbasins,whereas channel-bank sources were dominant in the Mission Lake subbasin. On the sole basis of 137Cs activity,surface-soil sources contributed the most fine-grained sediment to Atchison County Lake,and channel-bank sources contributed the most fine-grained sediment to Banner Creek Reservoir and Mission Lake. Both the seven-indicator consensus and 137Cs indicated that channel-bank sources were dominant for Perry Lake and that channel-bank sources increased in importance with distance downstream in the basin. | K. E. JURACEK A. C. ZIEGLER | 2009 | International Journal of Sediment Research2009,24,1: | 5 |
| 4 | ^(13)C-辛酸呼吸试验测定糖尿病胃固体排空功能的重复性研究显示文摘目的 观察13 C 辛酸呼吸试验测定糖尿病患者胃固体排空时间及其变异性 ,以及心自主神经病变和病理性胃排空状况对其的影响。方法 9例对照者和 15例糖尿病患者 [平均糖基化血红蛋白 (HbA1c) 7 8% ]1周内行 2次13 C 辛酸呼吸试验 ,采用非线性回归法计算半排空时间 (t1/ 2 )和缓慢期时间 (tlag) ,同时采用心自主神经功能试验判断有无心自主神经病变。结果 对照组t1/ 2 批内CV为 11 7%、tlag批内CV为 19 4% ,糖尿病患者t1/ 2 批内CV为 17 8%、tlag批内CV为 2 8 2 % ,对照者和糖尿病患者间差异无显著性。t1/ 2 和tlag的批内CV在糖尿病患者伴有和无心自主神经病变之间以及在正常胃排空时间和延迟性胃排空时间之间差异无显著性。结论 13 C 辛酸呼吸试验测定胃固体排空功能有较高的重复性 ,并不受心自主神经病变和病理性胃排空的影响。 | 冯波 Dan Ziegler | 2001 | 中华核医学杂志2001,21,2: | 5 |
| 5 | 慢性胰岛素刺激对胰岛素受体后不同信号转导途径的下降调节显示文摘目的 研究胰岛素慢性刺激对人肝癌细胞株 (HepG2 )胰岛素受体后不同信号转导途径的影响。方法 HepG2 细胞在无血清条件下与不同浓度的胰岛素 ( 0~ 10 0nmol/L)温育 16h ,然后用 10 0nmol/L胰岛素急性刺激 1min。这些细胞的溶解物中的胰岛素受体 β亚单位 (IRβ) ,胰岛素受体底物 (IRS) 1,IRS 2 ,磷酯酰肌醇 3激酶 (PI3K)的调节亚单位P85 ,有丝分裂原激活蛋白激酶 (MAPK)的蛋白表达水平和MAPK的磷酸化水平通过Western免疫印迹法测定 ,IRβ、IRS 1/ 2的蛋白磷酸化水平以及IRS 1/ 2与P85的结合反应用特异性抗体的免疫沉淀法。结果 胰岛素 1min急性刺激能迅速导致IRβ、IRS 1、IRS 2的酪氨酸磷酸化和MAPK的磷酸化 ,以及IRS 1( 2 )与P85的相互作用而激活PI3K。高浓度胰岛素慢性刺激显著降低了IRβ、IRS 1和IRS 2的酪氨酸磷酸化。细胞用 10 0nmol/L胰岛素预温育 16h后 ,IRβ、IRS 1和IRS 2的磷酸化水平降至最低值 ,分别为对照水平的 2 2 .2 % (P <0 .0 1)、10 .9% (P <0 .0 1)和 2 2 .0 % (P<0 .0 1) ,与IRS的磷酸化变化相平行 ,IRS 1和IRS 2与PI3K的相互作用分别降低至对照水平的 3 4.3 %(P <0 .0 1)和 3 0 .0 % (P <0 .0 1) ,MAPK的磷酸化水平降低至对照水平的 16.4% (P <0 .0 1)。 | 袁莉 Reinhard ZIEGLER Andreas HAMANN | 2003 | 中华内分泌代谢杂志2003,19,4: | 5 |
| 6 | Quantification of Obstructive and Nonobstructive Coronary Lesions by 64-Slice Computed Tomography显示文摘 | Alexander W. Leber Andreas Knez Franz von Ziegler Alexander Becker Konstantin Nikolaou Stephan Paul Bernd Wintersperger Maximilian Reiser Christoph R. Becker Gerhard Steinbeck Peter Boekstegers | 2005 | Journal of the American College of Cardiology2005,,1: | 4 |
| 7 | 应对辅助生殖技术中的风险安全管理挑战:一种积极性方案显示文摘医学各专业在安全保障方面远落后于其他行业,借助于辅助生殖技术的不育诊疗概莫能外。航空业多年来所开发实施的安全风险管理(RSM)让如今的全球航空安全上升到了一个卓越的水平,而将它们的技术经验应用到医学行业,相信将会在医疗效能和安全上带来极大的助益。本文描述了在不育和辅助生殖技术领域贯彻实施这类RSM的依据,而这一特殊的医学专业领域有望成为在整个医学行业实施RSM的试验田。 | Dominique de Ziegler Pietro Santulli Isabelle Streuli Rebecca Monfat Anna Raggi Alexandra Ambrosetti Paul Pirtea Charles Chapron 罗宏志(译) | 2014 | 生殖医学杂志2014,23,3: | 4 |
| 8 | Intestinal Tumorigenesis Initiated by Dedifferentiation and Acquisition of Stem-Cell-like Properties显示文摘 | Sarah Schwitalla Alexander A. Fingerle Patrizia Cammareri Tim Nebelsiek Serkan I. G?ktuna Paul K. Ziegler Ozge Canli Jarom Heijmans David J. Huels Guenievre Moreaux Rudolf A. Rupec Markus Gerhard Roland Schmid Nick Barker Hans Clevers Roland Lang Jens Neu | 2013 | Cell2013,,: | 3 |
| 9 | 谷氨酰胺强化的营养支持:是否省氮并节省费用显示文摘 | Ziegler TR Bazargan N Galloway JR 何桂珍 | 2005 | 中国临床营养杂志2005,13,1: | 3 |
| 10 | Numerical experiments of disturbance to the solar atmosphere caused by eruptions显示文摘Despite extensive research on various global waves in solar eruptions, debate continues on the intrinsic nature of them. In this work, we performed numerical experiments of the coronal mass ejection with emphases on the associated large-scale MHD waves. A fast-mode shock forms in front of the flux rope during the eruption with a dimming region following it, and the development of a three-component structure of the ejecta is observed. At the flank of the flux rope, the slow-mode shock and the velocity vortices are also invoked. The dependence of the eruption energetics on the strength of the background field and the coronal plasma density distribution is apparent: the stronger the background field is, and/or the lower the coronal plasma density is, the more energetic the eruption is. In the lower Alfve′n speed environment, the slow mode shock and the large scale velocity vortices may be the source of the EIT wave. In the high Alfve′n speed environment, on the other hand, the echo due to the reflection of the fast shock on the bottom boundary could be so strong that its interaction with the slow mode shock and the velocity vortices produces the second echo propagating downward and causing the secondary disturbance to the boundary surface. We suggest that this second echo, together with the slow shock and the velocity vortices, could constitute a possible candidate of the source for the EIT wave. | MEI ZhiXing UDO Ziegler LIN Jun | 2012 | Science China(Physics,Mechanics & Astronomy)2012,55,7: | 3 |
| 11 | 泥盆纪最早期牙形刺带化石在蒙古南戈壁幕使盖(Mushgai)地区“尕屋(Gavuu)”段的首次发现显示文摘在蒙古南戈壁的Bayan KhoshuuRuins剖面原归入到志留系Mandalovoo组尕屋 (Gavuu)段的地层中发现了牙形刺Caudicrioduswoschimidtiwoschmidti,这是泥盆纪最早期牙形刺带化石在蒙古的首次发现。尕屋 (Gavuu)段的下部属志留系 ,但其上部 ,即采集牙形刺样品M 9~M 12的层位肯定属下泥盆统 (下洛霍考夫阶 ) ,而不是下志留统。Mandalovoo组应当改为Mandalovoo群 。 | 王成源 Ziegler W. Minjin Ch. Sersmaa G. Munchtsetseg J. Gereltsetseg L. Nadya I | 2003 | 世界地质2003,22,1: | 3 |
| 12 | A New Species of Rhacophorus(Amphibia:Anura:Rhacophoridae)from Vietnam显示文摘We describe a new species of Rhacophorus based on two adult specimens collected from Hoa Binh Province, northern Vietnam. Rhacophorus hoabinhensis sp. nov. is distinguishable from its congeners on the basis of a combination of the following morphological characters: size small(SVL 31.1–32.5 mm in males); head slightly longer than wide; vomerine teeth absent; snout short(SNL/SVL 0.16); dorsal skin smooth; forearm and tarsus with dermal fringes; dermal appendage at vent present; webbing formula on fingers Ⅰ12/3-12/3 Ⅱ1-2 Ⅲ1-1 Ⅳ and on toes Ⅰ3/4-1 Ⅱ1/2-1Ⅲ1/2-1 Ⅳ1-1/2Ⅳ; dorsal surface grey yellow with brown spots; lower jaw region dark grey, throat, chest and belly cream; anterior and posterior thighs, as well as ventral surface of tibia orange. The interspecific uncorrected genetic distances(16 S rRNA gene) between the new species from Hoa Binh and other analyzed congeners varied from 9.8% to 17.4%. In the phylogenetic analyses, the new species revealed to be a representative of Rhacophorus and was nested within the R. hoanglienensis-orlovi species group. | Tao Thien NGUYEN Cuong The PHAM Truong Quang NGUYEN Hoa Thi NINH Thomas ZIEGLER | 2017 | Asian Herpetological Research2017,18,4: | 2 |
| 13 | The First Discovery of the Earliest Devonian Conodont Zonal Fossil from the 'Gavuu Member' in Mushgai Area of South Gobi,Mongolia显示文摘Conodont Caudicriodus woschimidti woschmidti has been found from a big outcrop (hill) of the Bayan-Kho-shuu Ruins Section which was previously assigned to the Silurian Gavuu Member of the Mandalovoo Formation. This is first time to find the lowermost Devonian conodont zonal fossil in Mongolia. The lower part of the Gavuu Member is Sil-urian. But the strata from where we collected samples M-9~M-12 definitely belong to Lower Devonian (lower Lochko-vian) rather than Lower Silurian. The Mandalovoo Formation should be named Mandalovoo Group, and its three mem-bers should be changed into three formations. | Chengyuan Wang W. Ziegler Ch. Minjin G. Sersmaa J. Munchtsetseg L. Gereltsetseg I. Nadya | 2003 | Global Geology2003,8,1: | 2 |
| 14 | Early infant male circumcision:Systematic review,risk-benefit analysis,and progress in policy显示文摘AIM To determine whether recent evidence-based United States polices on male circumcision(MC) apply to comparable Anglophone countries,Australia and New Zealand.METHODS Articles in 2005 through 2015 were retrieved from PubM ed using the keyword 'circumcision' together with 36 relevant subtopics.A further PubM ed search was performed for articles published in 2016.Searches of the EMBASE and Cochrane databases did not yield additional citable articles.Articles were assessed for quality and those rated 2+ and above according to the Scottish Intercollegiate Grading System were studied further.The most relevant andrepresentative of the topic were included.Bibliographies were examined to retrieve further key references.Randomized controlled trials,recent high quality systematic reviews or meta-analyses(level 1++ or 1+ evidence) were prioritized for inclusion.A risk-benefit analysis of articles rated for quality was performed.For efficiency and reliability,recent randomized controlled trials,metaanalyses,high quality systematic reviews and large welldesigned studies were used if available.Internet searches were conducted for other relevant information,including policies and Australian data on claims under Medicare for MC.RESULTS Evidence-based policy statements by the American Academy of Pediatrics(AAP) and the Centers for Disease Control and Prevention(CDC) support infant and later age male circumcision(MC) as a desirable public health measure.Our systematic review of relevant literature over the past decade yielded 140 journal articles that met our inclusion criteria.Together,these showed that early infant MC confers immediate and lifelong benefits by protecting against urinary tract infections having potential adverse long-term renal effects,phimosis that causes difficult and painful erections and 'ballooning' during urination,inflammatory skin conditions,inferior penile hygiene,candidiasis,various sexually transmissible infections in both sexes,genital ulcers,and penile,prostate and cervical cancer.Our risk-benefit analysis showed that benefits exceeded procedural risks,which are predominantly minor,by up to 200 to 1.We estimated that more than 1 in 2 uncircumcised males will experience an adverse foreskin-related medical condition over their lifetime.Wide-ranging evidence from surveys,physiological measurements,and the anatomical location of penile sensory receptors responsible for sexual sensation strongly and consistently suggested that MC has no detrimental effect on sexual function,sensitivity or pleasure.United States studies showed that early infant MC is cost saving.The evidence supporting early infant MC has further strengthened since the positive AAP and CDC reviews.CONCLUSION Affirmative MC policies are needed in Australia and New Zealand.Routine provision of accurate,unbiased education,and access in public hospitals,will maximize health and financial benefits. | Brian J Morris Sean E Kennedy Alex D Wodak Adrian Mindel David Golovsky Leslie Schrieber Eugenie R Lumbers David J Handelsman John B Ziegler | 2017 | World Journal of Clinical Pediatrics2017,6,1: | 2 |
| 15 | 蒙古南戈壁泥盆纪(埃姆斯期—艾菲尔期)牙形刺(英文)显示文摘在蒙古南戈壁地区丘隆组(Chuluun Formation)和查干卡勒噶组(Tsagaankhaalga Formation) 发现的牙形刺证明丘隆组的时代为晚埃姆斯期,查干卡勒噶组的时代为早艾菲尔期,与以前大化石所确定的时代一致。但艾菲尔阶的底界暂时还无法准确确定,蒙古南戈壁地区艾菲尔阶牙形刺动物群与同期北美的牙形刺动物群相似,但也包含一些地方性分子,蒙古海相艾菲尔期的沉积可能不完整。本文描述了2 个命名新种,Caudicriodus delicatus sp. nov., C. paraculicellus sp. nov.,一个未命名新种,Caudicriodus sp. nov. A 和一个新亚种, Cuadicriodus angustus cauda subsp. nov.。 | 王成源 Minjin CHULUUN Karsten WEDDIGE Willi ZIEGLER Sersmaa GONCHIGDORJ Munchtsetseg JUGDERNAMJIL Gereltsetseg LHAGVA Undarya JALBAA | 2005 | 微体古生物学报2005,22,1: | 2 |
| 16 | Dual-source CT cardiac imaging: initial experience显示文摘 | Thorsten R. C. Johnson Konstantin Nikolaou Bernd J. Wintersperger Alexander W. Leber Franz Ziegler Carsten Rist Sonja Buhmann Andreas Knez Maximilian F. Reiser Christoph R. Becker | 2006 | European Radiology2006,,7: | 2 |
| 17 | Quantification of Obstructive and Nonobstructive Coronary Lesions by 64-Slice Computed Tomography显示文摘 | Alexander W. Leber Andreas Knez Franz von Ziegler Alexander Becker Konstantin Nikolaou Stephan Paul Bernd Wintersperger Maximilian Reiser Christoph R. Becker Gerhard Steinbeck Peter Boekstegers | 2005 | Journal of the American College of Cardiology2005,,1: | 2 |
| 18 | 基于太阳爆发灾变模型的数值实验显示文摘在Isenberg等人发展的灾变模型基础上根据接近真实的日冕环境,通过数值实验,对磁通量绳的平衡高度对光球磁场变化的响应开展了研究.利用NIRVANA程序进行了计算.日冕的等离子密度分布采用了一个半经验的模型,模拟中包含了物理耗散.考察了:磁通量绳的平衡位置及其演化特征;参考半径的变化对磁通量绳平衡位置的影响;磁通量绳内部平衡的性质以及在磁通量绳失去平衡之后一段时间内的动力学与运动学特征.结果表明:数值实验中得到的磁通量绳的平衡态位置与Isenberg等人的理论结果有微小的偏离,但是演化特征基本一致,在临界点处系统迅速失去平衡,向爆发态演化;参考半径的变化对磁通量绳平衡位置的影响与灾变模型给出的结果基本一致;磁通量绳在随着宏观磁结构演化的同时,还通过自身的调节达到内部平衡,当磁通量绳的内部和外部平衡都实现之后,系统整体也就达到了平衡状态;在爆发态下,磁通量绳的运动特征与Lin-Forbes模型和观测给出的结果一致,并且在通量绳的前方有快模激波出现;由于数值实验中包括了耗散,爆发过程中的磁能向其他形式能量的转换非常明显. | 谢小妍 ZIEGLER Udo 梅志星 吴宁 林隽 | 2017 | 天文学报2017,58,6: | 2 |
| 19 | Loss of p53 in Enterocytes Generates an Inflammatory Microenvironment Enabling Invasion and Lymph Node Metastasis of Carcinogen-Induced Colorectal Tumors显示文摘 | Sarah Schwitalla Paul K. Ziegler David Horst Valentin Becker Irina Kerle Yvonne Begus-Nahrmann André Lechel K. Lenhard Rudolph Rupert Langer Julia Slotta-Huspenina Franz G. Bader Olivia Prazeres da Costa Markus F. Neurath Alexander Meining Thomas Kirchner | 2013 | Cancer Cell2013,,: | 2 |
| 20 | 蒙古南部新金斯特地区下泥盆统洛霍考夫阶察甘安布拉格组牙形刺的新记录(英文)显示文摘蒙古南部新金斯特地区萨克黑尔剖面察甘安布拉格组上部发现的牙形刺, 包括Caudicriodusneowos chmidtisp. nov., Caudicriodussp. A, Kimognathussp., “Ozarkodina”planilingua, Pandorinellinaoptima, Ozarkodinaexcavata, 清楚地表明察甘安布拉格组上部应当归到中洛霍考夫阶(泥盆系)而不是像以往那样归到中-上志留统。海相温洛克统和罗德洛统地层在蒙古南部是否存在还需要寻找证据。文章描写了一个新种Caudicriodusneowos chmidtisp. nov.和一个未定种Caudicriodussp. A。 | 王成源 Karsten W EDDIGE Willi ZIEGLER Ch MINJIN | 2005 | 古生物学报2005,44,1: | 2 |