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| 1 | IoC容器和Dependency Injection模式显示文摘loC,一种轻量级容器,试图取代庞大而复杂的J2EE技术。如今正在开源Java社群中掀起一股热潮,同时loC的设计模式讨论也进行的如火如茶。大师级的Martin Fowler为我们带来这篇文章,先睹为快。 | Martin Fowler 透明 | 2004 | 程序员2004，，3： | 4 |
| 2 | The New Methodology显示文摘In the past few years there’s been a rapidly growing interest in “lightweight” methodologies. Alternatively characterized as an antidote to bureaucracy or a license to hack they’ve stirred up interest all over the software landscape. In this essay I explore the reasons for lightweight methods, focusing not so much on their weight but on their adaptive nature and their people first orientation. I also give a summary and references to the processes in this school and consider the factors that should influence your choice of whether to go down this newly trodden path. | Martin Fowler 651 W Washington Blvd,Suite 500,Chicago,IL 60661, USA | 2001 | Wuhan University Journal of Natural Sciences2001，6，Z1： | 2 |
| 3 | A UML testing framework显示文摘 | FOWLER Martin | 1999 | Software Development Magazine1999，，： | 1 |
| 4 | Increasing rates of cardiac device infections among medicare beneficiaries: 1990–1999显示文摘 | Christopher H Cabell Paul A Heidenreich Vivian H Chu Christopher M Moore Martin E Stryjewski G.Ralph Corey Vance G Fowler | 2004 | American Heart Journal2004，，4： | 1 |
| 5 | Hydrogen isotopic compositions of individual alkanes as a new approach to petroleum correlation: case studies from the Western Canada Sedimentary Basin显示文摘 | Maowen Li Yongsong Huang Mark Obermajer Chunqing Jiang Lloyd R Snowdon Martin G Fowler | 2001 | Organic Geochemistry2001，，12： | 1 |
| 6 | Natural history of chronic hepatitis B virus infection in taiwan: Studies of hepatitis B virus DNA in serum 显示文摘 | Chu Chia-Ming Karayiannis Peter Fowler Martin J F | 1985 | Hepatology1985，5，3： | 1 |
| 7 | Accreditation and quality assurance for Radiation Therapy Oncology Group: Multicenter clinical trials using Stereotactic Body Radiation Therapy in lung cancer显示文摘 | Robert Timmerman James Galvin Jeff Michalski William Straube Geoffrey Ibbott Elizabeth Martin Ramzi Abdulrahman Suzanne Swann Jack Fowler Hak Choy | 2006 | Acta Oncologica2006，，7： | 1 |
| 8 | Patterns of Enterprise Application Architecture显示文摘 | Fowler Martin | 2003 | AddisonWesley2003，，： | 1 |
| 9 | A prospective, observational registry of patients with severe sepsis: The Canadian Sepsis Treatment and Response Registry显示文摘 | Claudio M. Martin Fran Priestap Harold Fisher Robert A. Fowler Daren K. Heyland Sean P. Keenan Christopher J. Longo Teresa Morrison Diane Bentley Neil Antman | 2009 | Critical Care Medicine2009，，1： | 1 |
| 10 | The clinical laboratory practitioner 显示文摘 | Fowler D Martin T Spence L | 2005 | Clin Lab Sci2005，18，4： | 1 |
| 11 | Applications of petroleum geochemistry to exploration and reservoir management显示文摘 | Ken E Peters Martin G Fowler | 2002 | Organic Geochemistry2002，，1： | 1 |
| 12 | Applications of petroleum geochemistry to exploration and reservoir management显示文摘 | Ken E Peters Martin G Fowler | 2002 | Organic Geochemistry2002，33，1： | 1 |
| 13 | Homocysteine, Vitamin B12, and Folic Acid Levels in Alzheimer’s Disease, Mild Cognitive Impairment, and Healthy Elderly: Baseline Characteristics in Subjects of the Australian Imaging Biomarker Lifestyle Study显示文摘 | Noel G. Faux Kathryn A. Ellis Lorine Porter Chris J. Fowler Simon M. Laws Ralph N. Martins Kelly K. Pertile Alan Rembach Chris C. Rowe Rebecca L. Rumble Cassandra Szoeke Kevin Taddei Tania Taddei Brett O. Trounson Victor L. Villemagne Vanessa Ward David A | 2011 | Journal of Alzheimer’s Disease2011，，4： | 1 |
| 14 | Refactoring: Improving the Design of Existing Code 显示文摘 | | 1999 | Addison-Wesley1999，8，2： | 1 |
| 15 | Spatial patterns and temporal trends in mercury concentrations, precipitation depths, and mercury wet deposition in the North American Great Lakes region, 2002–2008显示文摘 | Martin R. Risch David A. Gay Kathleen K. Fowler Gerard J. Keeler Sean M. Backus Pierrette Blanchard James A. Barres J. Timothy Dvonch | 2011 | Environmental Pollution2011，，： | 1 |
| 16 | Bakken/Madison petroleum systems in the Canadian Williston Basin. Part 2: molecular markers diagnostic of Bakken and Lodgepole source rocks显示文摘 | Chunqing Jiang Maowen Li Kirk G Osadetz Lloyd R Snowdon Mark Obermajer Martin G Fowler | 2001 | Organic Geochemistry2001，，9： | 1 |
| 17 | ACR Appropriateness Criteria Colorectal Cancer Screening显示文摘 | Judy Yee David H. Kim Max P. Rosen Tasneem Lalani Laura R. Carucci Brooks D. Cash Barry W. Feig Kathryn J. Fowler Douglas S. Katz Martin P. Smith Vahid Yaghmai | 2014 | Journal of the American College of Radiology2014，，： | 1 |
| 18 | Using Metadata显示文摘 | Martin Fowler | 2002 | IEEES of software2002，19，6： | 1 |
| 19 | 面向语言编程——面向对象之后的革命显示文摘人们使用计算机描述世界的方式一直在不断地变化,从早期的汇编语言,到函数式言语,比如Lisp,再到面向过程、面向对象语言,和今天无限风光的动态语言等等。语言的变更表现了计算机需要理解的现实世界正在快速地走向复杂,也说明了人们为了更简单地解决复杂问题,一直在不断地努力着。风靡上世纪九十年代的面向对象思想,通过分层结构和树状的抽象提供了一种有效的建模范式,但是今天随着业务日趋复杂,面向对象这种'精确'的建模方式已经渐渐呈现疲态。最近,Martin Fowler和Neal Ford在TSSJS Barcelona一起讲述了领域特定语言(DSL)背后的理论以及现实世界中的案例,向您解释了面向对象之后,人们如何利用更好的工具迎接更复杂的应用。 | Martin Fowler Neal Ford 高昂 | 2008 | 程序员2008，，5： | 0 |
| 20 | Impact of high dose vitamin C on platelet function显示文摘AIM To examine the effect of high doses of vitamin C(VitC) on ex vivo human platelets(PLTs).METHODS Platelet concentrates collected for therapeutic or prophylactic transfusions were exposed to:(1) normal saline(control);(2) 0.3 mmol/L VitC(Lo VitC); or(3) 3 mmol/L VitC(Hi VitC, final concentrations) and stored appropriately. The Vit C additive was preservative-free buffered ascorbic acid in water, pH 5.5 to 7.0, adjusted with sodium bicarbonate and sodium hydroxide. The doses of Vit C used here correspond to plasma Vit C levels reported in recently completed clinical trials. Prior to supplementation, a baseline sample was collected for analysis. PLTs were sampled again on days 2, 5 and 8 and assayed for changes in PLT function by: Thromboelastography(TEG), for changes in viscoelastic properties; aggregometry, for PLT aggregation and adenosine triphosphate(ATP) secretion in response to collagen or adenosine diphosphate(ADP); and flow cytometry, for changes in expression of CD-31, CD41 a, CD62 p and CD63. In addition, PLT intracellular Vit C content was measured using a fluorimetric assay for ascorbic acid and PLT poor plasma was used for plasma coagulation tests [prothrombin time(PT), partial thrombplastin time(PTT), functional fibrinogen] and Lipidomics analysis(UPLC ESI-MS/MS).RESULTS VitC supplementation significantly increased PLTs intracellular ascorbic acid levels from 1.2 mmol/L at baseline to 3.2 mmol/L(Lo VitC) and 15.7 mmol/L(Hi VitC, P < 0.05). VitC supplementation did not significantly change PT and PTT values, or functional fibrinogen levels over the 8 d exposure period(P > 0.05). PLT function assayed by TEG, aggregometry and flow cytometry was not significantly altered by Lo or Hi VitC for up to 5 d. However, PLTs exposed to 3 mmol/L VitC for 8 d demonstrated significantly increased R and K times by TEG and a decrease in the α-angle(P < 0.05). There was also a fall of 20 mm in maximum amplitude associated with the Hi VitC compared to both baseline and day 8 saline controls. Platelet aggregation studies, showed uniform declines in collagen and ADP-induced platelet aggregations over the 8-d study period in all three groups(P > 0.05). Collagen and ADP-induced ATP secretion was also not different between the three groups(P > 0.05). Finally, VitC at the higher dose(3 mmol/L) also induced the release of several eicosanoids including thromboxane B2 and prostaglandin E2, as well as products of arachidonic acid metabolism via the lipoxygenases pathway such as 11-/12-/15-hydroxyicosatetraenoic acid(P < 0.05).CONCLUSION Alterations in PLT function by exposure to 3 mmol/L VitC for 8 d suggest that caution should be exerted with prolonged use of intravenous high dose VitC. | Bassem M Mohammed Kimberly W Sanford Bernard J Fisher Erika J Martin Daniel Contaifer Jr Urszula Osinska Warncke Dayanjan S Wijesinghe Charles E Chalfant Donald F Brophy Alpha A Fowler Ⅲ Ramesh Natarajan | 2017 | World Journal of Critical Care Medicine2017，6，1： | 0 |
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