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| 1 | Use of portal pressure studies in the management of variceal haemorrhage显示文摘Portal hypertension occurs as a complication of liver cirrhosis and complications such as variceal bleeding lead to significant demands on resources. Endoscopy is the gold standard method for screening cirrhotic patients however universal endoscopic screening may mean a lot of unnecessary procedures as the presence of oesophageal varices is variable hence a large time and cost burden on endoscopy units to carry out both screening and subsequent follow up of variceal bleeds. A less invasive method to identify those at high risk of bleeding would allow earlier prophylactic measures to be applied. Hepatic venous pressure gradient (HVPG) is an acceptable indirect measurement of portal hypertension and predictor of the complications of portal hypertension in adult cirrhotics. Varices develop at a HVPG of 10-12 mmHg with the appearance of other complications with HPVG > 12 mmHg. Variceal bleeding does not occur in pressures under 12 mmHg. HPVG > 20 mmHg measured early after admission is a significant prognostic indicator of failure to control bleeding varices, indeed early transjugular intrahepatic portosystemic shunt (TIPS) in such circumstances reduces mortality significantly. HVPG can be used to identify responders to medical therapy. Patients who do not achieve the suggested reduction targets in HVPG have a high risk of rebleeding despite endoscopic ligation and may not derive significant overall mortality benefit from endoscopic intervention alone, ultimately requiring TIPS or liver transplantation. Early HVPG measurements following a variceal bleed can help to identify those at risk of treatment failure who may benefit from early intervention with TIPS. Therefore, we suggest using HVPG measurement as the investigation of choice in those with confirmed cirrhosis in place of endoscopy for intitial variceal screening and, where indicated, a trial of B-blockade, either intravenously during the initial pressure study with assessment of response or oral therapy with repeat HVPG six weeks later. In those with elevated pressures, primary medical prophylaxis could be commenced with subsequent close monitoring of HVPG thus negating the need for endoscopy at this point. All patients presenting with variceal haemorrhage should undergo HVPG measurement and those with a gradient greater than 20 mmHg should be considered for early TIPS. By introducing portal pressure studies into a management algorithm for variceal bleeding, the number of endoscopies required for further intervention and follow up can be reduced leading to significant savings in terms of cost and demand on resources. | Jennifer Addley Tony CK Tham William Jonathan Cash | 2012 | World Journal of Gastrointestinal Endoscopy2012，4，7： | 37 |
| 2 | Diagnosis of intestinal tuberculosis using a monoclonal antibody to Mycobacterium tuberculosis显示文摘AIM:To investigate the utility of immunohistochemical(IHC) staining with an antibody to Mycobacterium tuberculosis(M.tuberculosis) for the diagnosis of intestinal tuberculosis(TB).METHODS:We retrospectively identified 10 patients(4 males and 6 females;mean age = 65.1 ± 13.6 years) with intestinal TB.Clinical characteristics,including age,gender,underlying disease,and symptoms were obtained.Chest radiograph and laboratory tests,including sputum Ziehl-Neelsen(ZN) staining,M.tuberculosis culture,and sputum polymerase chain reaction(PCR) for tubercle bacilli DNA,as well as Tuberculin skin test(TST) and QuantiFERON-TB gold test(QFT),were examined.Colonoscopic records recorded on the basis of Sato's classification were also reviewed,in addition to data from intestinal biopsies examined for histopathological findings,including hematoxylin and eosin staining,and ZN staining,as well as M.tuberculosis culture,and PCR for tubercle bacilli DNA.For the present study,archived formalin-fixed paraffin-embedded(FFPE) intestinal tissue samples were immunohistochemically stained using a commercially available species-specific monoclonal antibody to the 38-kDa antigen of the M.tuberculosis complex.These sections were also stained with the pan-macrophage marker CD68 antibody.RESULTS:From the clinical data,we found that no patients were immunocompromised,and that the main symptoms were diarrhea and weight loss.Three patients displayed active pulmonary TB,six patients(60%) had a positive TST,and 4 patients(40%) had a positive QFT.Colonoscopic findings revealed that all patients had type 1 findings(linear ulcers in a circumferential arrangement or linear ulcers arranged circumferentially with mucosa showing multiple nodules),all of which were located in the right hemicolon and/or terminal ileum.Seven patients(70%) had concomitant healed lesions in the ileocecal area.No acid-fast bacilli were detected with ZN staining of the intestinal tissue samples,and both M.tuberculosis culture and PCR for tubercle bacilli DNA were negative in all samples.The histopathological data revealed that tuberculous granulomas were present in 4 cases(40%).IHC staining in archived FFPE samples with anti-M.tuberculosis monoclonal antibody revealed positive findings in 4 patients(40%);the same patients in which granulomas were detected by hematoxylin and eosin staining.M.tuberculosis antigens were found to be mostly intracellular,granular in pattern,and primarily located in the CD68 + macrophages of the granulomas.CONCLUSION:IHC staining with a monoclonal antibody to M.tuberculosis may be an efficient and simple diagnostic tool in addition to classic examination methods for the diagnosis of intestinal TB. | Yasushi Ihama Akira Hokama Kenji Hibiya Kazuto Kishimoto Manabu Nakamoto Tetsuo Hirata Nagisa Kinjo Haley L Cash Futoshi Higa Masao Tateyama Fukunori Kinjo Jiro Fujita | 2012 | World Journal of Gastroenterology2012，18，47： | 12 |
| 3 | The Role of Endoscopy in the Assessment and Treatment of Esophageal Cancer显示文摘 | J.A. Evans D.S. Early V. Chandraskhara K.V. Chathadi R. Fanelli D.A. Fisher K. Foley J.H. Hwang T.L. Jue S. Pasha R. Sharaf A. Shergill J.A. Dominitz B.D. Cash | 2012 | Gastrointestinal Endoscopy2012，，： | 2 |
| 4 | Highly sensitive integrated flexible tactile sensors with piezoresistive Ge2Sb2Te5 thin films显示文摘Flexible tactile sensor has been extensively investigated as a key component for emerging electronics applications such as robotics,wearable devices,computer hardware,and security systems.Tactile sensors based on various one-dimensional materials have been widely explored.However,precise control of the direction and distribution of these nanomaterials remains a great challenge,and it has been difficult to scale down the device.Here,we introduce highly sensitive integrated flexible tactile sensors based on uniform phase-change Ge_(2)Sb_(2)Te_(5)(GST)thin films that can scale device size down,at least,to micrometer range.Significant piezoresistive effect has been observed in GST-based sensors,showing a giant gauge factor of 338.A proof of concept 5×5 sensor array functioning as a touch panel has been demonstrated.Also,the flexible GST tactile sensor has been utilized for monitoring of radial artery pulse.In addition to the well-known tunable electrical and optical properties,the piezoresistive GST films provide a versatile platform for the integration of sensing,recording,and displaying functions. | Zhiguang Wang Cunzheng Dong Xinjun Wang Menghui Li Tianxiang Nan Xianfeng Liang Huaihao Chen Yuyi Wei Haomiao Zhou Mohsen Zaeimbashi Syd Cash Nian-Xiang Sun | 2018 | npj Flexible Electronics2018，2，1： | 2 |
| 5 | Appropriate use of GI endoscopy显示文摘 | Dayna S. Early Tamir Ben-Menachem G. Anton Decker John A. Evans Robert D. Fanelli Deborah A. Fisher Norio Fukami Joo Ha Hwang Rajeev Jain Terry L. Jue Khalid M. Khan Phyllis M. Malpas John T. Maple Ravi S. Sharaf Jason A. Dominitz Brooks D. Cash | 2012 | Gastrointestinal Endoscopy2012，，6： | 2 |
| 6 | 纽约州立大学“树木学”、“园林植物配置”课程的教学特色分析显示文摘从教学内容、方法、学生成绩评定等方面对美国纽约州立大学农业技术学院的“树木学”、“园林植物配置”课程的教学特色进行了较为详尽的介绍与分析,阐述了这些课程对我国农林类高校相关课程教学的启示,以期对我国农林高校相关课程的教学有所借鉴。 | 童丽丽 CASH Christine 许晓岗 | 2019 | 金陵科技学院学报2019，35，3： | 2 |
| 7 | The role of endoscopy in the management of obscure GI bleeding显示文摘 | Laurel Fisher Mary Lee Krinsky Michelle A. Anderson Vasundhara Appalaneni Subhas Banerjee Tamir Ben-Menachem Brooks D. Cash G. Anton Decker Robert D. Fanelli Cindy Friis Norio Fukami M. Edwyn Harrison Steven O. Ikenberry Rajeev Jain Terry Jue Khalid Khan | 2010 | Gastrointestinal Endoscopy2010，，3： | 2 |
| 8 | The role of endoscopy in the evaluation of suspected choledocholithiasis显示文摘 | John T. Maple Tamir Ben-Menachem Michelle A. Anderson Vasundhara Appalaneni Subhas Banerjee Brooks D. Cash Laurel Fisher M. Edwyn Harrison Robert D. Fanelli Norio Fukami Steven O. Ikenberry Rajeev Jain Khalid Khan Mary Lee Krinsky Laura Strohmeyer Jason A | 2010 | Gastrointestinal Endoscopy2010，，1： | 2 |
| 9 | Complications of ERCP显示文摘 | Michelle A. Anderson Laurel Fisher Rajeev Jain John A. Evans Vasundhara Appalaneni Tamir Ben-Menachem Brooks D. Cash G. Anton Decker Dayna S. Early Robert D. Fanelli Deborah A. Fisher Norio Fukami Joo Ha Hwang Steven O. Ikenberry Terry L. Jue Khalid M. Kh | 2012 | Gastrointestinal Endoscopy2012，，3： | 2 |
| 10 | Management of antithrombotic agents for endoscopic procedures显示文摘 | Michelle A. Anderson Tamir Ben-Menachem S. Ian Gan Vasundhara Appalaneni Subhas Banerjee Brooks D. Cash Laurel Fisher M. Edwyn Harrison Robert D. Fanelli Norio Fukami Steven O. Ikenberry Rajeev Jain Khalid Khan Mary Lee Krinsky David R. Lichtenstein John | 2009 | Gastrointestinal Endoscopy2009，，6： | 2 |
| 11 | Optical character recognition by the method of moments显示文摘 | Cash G L Hatamian M | 1987 | Computer Vision Graphics and Image Processing1987，39，： | 1 |
| 12 | Linear summation of excitatory inputs by CA1 pyramidal neurons显示文摘 | Cash S Yuste R | | 0，，02： | 1 |
| 13 | Body-image attitudes among male marathon runners: A controlled comparative study显示文摘 | HUDDY D C CASH T F | 1997 | International Journal of Sport Psychology1997，28，3： | 1 |
| 14 | Reactive oxygen species and cellular oxygen sensing显示文摘 | Timothy P. Cash Yi Pan M. Celeste Simon | 2007 | Free Radical Biology and Medicine2007，，9： | 1 |
| 15 | Women′s psychosocial outcomes of breast augmentation with silicone gel-filled implants:a 2-year prospective study显示文摘 | Cash TF Duel LA Perkins LL | 2002 | Plast Reconstr Surg2002，109，6： | 1 |
| 16 | Proteomics:a new approach to the study of disease显示文摘 | Chambers G Lawrie L Cash P | 2000 | The Journal of Pathology2000，192，： | 1 |
| 17 | Insulation failure prediction in AC machines using line - neutral voltages 显示文摘 | CASH M A HABETLER T G KLIMAN G B | 1998 | IEEE Transactions on Industry Applications1998，34，6： | 1 |
| 18 | 查看详情显示文摘 | Cash K.J Ricci F Plaxco K.W | | 0，，： | 1 |
| 19 | Women's exposure to thin-and-beautiful media images:body image effects of media-ideal internalization and impact-reduciton intervenitons显示文摘 | Yamamiya Y Cash TF Melnyk SE Posavac HD Posavac SS | | 0，，01： | 1 |
| 20 | Beyond body image as a trait:the development and validation of the Body Image States Scale 显示文摘 | Cash TF Fleming EC Alindogan J | 2002 | Eat Disord2002，10，2： | 1 |
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