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| 1 | 评估大气细颗粒物暴露引起的全球疾病负担的一个综合风险函数显示文摘[背景]评估由于环境空气中细颗粒物(PM2.5)长期暴露引起的疾病负担,需要了解相对风险度(RR)函数的图形和幅度。然而,在世界上很多观察到高PM2.5环境浓度的地方,都缺乏足够的直接证据确定死亡RR函数的图形。[目的]建立可用于全球PM2.5暴露范围内成人死因的RR函数:缺血性心脏病(IHD)、脑血管疾病(脑卒中)、慢性阻塞性肺病(COPD)和肺癌(LC)。建立急性下呼吸道感染(ALRI)发病的RR函数,用于估算〈5岁的儿童中死亡率和健康生活损失年数。[方法]通过整合现有的来自于环境空气污染(AAP)、二手烟草烟雾、家用固体烹饪用燃料和主动吸烟(AS)等研究的RR信息,拟合综合暴露-反应(IER)模型。采用颗粒物质的吸入剂量,通过转化AS暴露来估计全年PM2.5的暴露当量。在估算全球环境PM2.5浓度的基础上,得出各国的人群归因分数(PAFs)。[结果]与以往负担评估中使用的其他7种模型相比,IER模型是一种优越的RR预测方法。在不同国家中,归因于AAP暴露的PAF百分数各不相同,分别为:IHD,2~41;脑卒中,1~43;COPD,〈1~21;LC,〈1~25;ALRI,〈1~38。[结论]我们建立了一种以细颗粒物为基础的RR模型,它通过整合来自不同类型的燃烧所产生颗粒物排放的RR信息,涵盖全球范围的暴露。当获得新的RR信息时,可以对这个模型进行更新。 | Richard T.Burnett C.Arden Pope III Majid Ezzati Casey Olives Stephen S.Lim Sumi Mehta Hwashin H.Shin Gitanjali Singh Bryan Hubbell Michael Brauer H.Ross Anderson Kirk R.Smith John R.Balmes Nigel G.Bruce Haidong Kan Francine Laden Annette Prüss-Ustün Michelle C.Turner Susan M.Gapstur W.Ryan Diver Aaron Cohen 何蓉 张伊人 金泰廙 | 2014 | 环境与职业医学2014，31，11： | 80 |
| 2 | 西加拿大沉积盆地Cardium组致密油资源评价显示文摘西加拿大盆地Cardium组以岩性为主要控制因素的油气藏边缘或油气藏之间发育一种被称为裙边油藏的非常规致密油资源,应用基于地质模型的随机模拟方法对Cardium组致密油资源量进行了预测。基于地质模型的随机模拟由3部分组成:地质模型建立、资源模型建立和随机模拟。采用统计学方法将分散在不同资料中有关资源丰度及其空间分布的信息有效地提取出来,并通过数学模型加以整理和重新组合,预测结果不仅包括资源量,同时给出其空间分布并指出勘探风险,可为勘探提供决策依据。预测结果表明,Cardium组总地质资源量(常规+非常规)为46×108m3,待发现的致密油地质资源量为29×108m3,目前技术和经济条件下可采资源量为1.1×108m3,不到待发现地质资源量的4%,但约占Cardium组总可采资源量的38%。基于Cardium组水平井资料,利用根据生产井产量递减推算的单井最终可采储量方法对基于地质模型随机模拟方法的评价结果进行检验,两种方法得到的可采资源量均值相差不大,证明基于地质模型的随机模拟评价结果可靠。 | 谌卓恒 Kirk G Osadetz | 2013 | 石油勘探与开发2013，40，3： | 51 |
| 3 | 生物技术与制浆造纸工业(上)显示文摘就生物技术在制浆造纸工业的应用现况及其前景作出综述。文章涉及的三个主要方面包括导致木素降解的真菌体系及其应用,多糖类降解体系及其利用,以及其他体系的生物技术。在论述中,特别注意到介绍可望在中国应用的某些最新成果。 | 张厚民 Kirk,TK | 1994 | 中国造纸1994，13，4： | 21 |
| 4 | Model for end-stage liver disease score versus Child score in predicting the outcome of surgical procedures in patients with cirrhosis显示文摘AIM:To determine factors affecting the outcome of patients with cirrhosis undergoing surgery and to compare the capacities of the Child-Turcotte-Pugh(CTP) and model for end-stage liver disease(MELD)score to predict that outcome. METHODS:We reviewed the charts of 195 patients with cirrhosis who underwent surgery at two teaching hospitals over a five-year period.The combined endpoint of death or hepatic decompensation was considered to be the primary endpoint. RESULTS:Patients who reached the endpoint had a higher MELD score,a higher CTP score and were more likely to have undergone an urgent procedure.Among patients undergoing elective surgical procedures,no statistically significant difference was noted in the mean MELD(12.8±3.9 vs 12.6±4.7,P=0.9)or in the mean CTP(7.6±1.2 vs 7.7±1.7,P=0.8)between patients who reached the endpoint and those who did not.Both mean scores were higher in the patients reaching the endpoint in the case of urgent procedures(MELD:22.4± 8.7 vs 15.2±6.4,P=0.0007;CTP:9.9±1.8 vs 8.5±1.8, P=0.008).The performances of the MELD and CTP scores in predicting the outcome of urgent surgery were only fair,without a significant difference between them (AUC=0.755±0.066 for MELD vs AUC=0.696±0.070 for CTP,P=0.3). CONCLUSION:The CTP and MELD scores performedequally,but only fairly in predicting the outcome of urgent surgical procedures.Larger studies are needed to better define the factors capable of predicting the outcome of elective surgical procedures in patients with cirrhosis. | Maarouf A Hoteit Amaar H Ghazale Andrew J Bain Eli S Rosenberg Kirk A Easley Frank A Anania Robin E Rutherford | 2008 | World Journal of Gastroenterology2008，14，11： | 16 |
| 5 | Seminal biomarkers for the evaluation of male infertility显示文摘为努力与他们的搭挡一起怀孕的男人,诊断工具被限制并且经常由仅仅标准精液分析组成。这基线测试用作男富饶的一个粗略的评价,离开需要另外的诊断 biomarkers 的病人和临床医生。精液从因此,这评论在某些男不孕情形在当前、新奇的精液的 biomarkers 上集中包括自然富饶,区分精子缺乏病原学,并且预言的繁殖的腺帮助了的男性包含分子的最高的集中繁殖技术成功。当前可得到的测试包括 antisperm 抗体试金, DNA 破碎索引,在 situ 杂交的精子荧光,和另外的历史的精子功能的测试。当前的试金的差的诊断能力导致了继续的努力发现更预兆的 biomarkers。genomics, epigenetics, proteomics, transcriptomics,和为新奇男不孕 biomarkers 的发展的 metabolomics 抓住诺言的地里的新兴的研究。TEX101, ECM1,和 ACRV1 的精液的基于蛋白质的试金已经是可得到的或在为临床的使用的最后的开发中。当我们试图理解男不孕的 pathophysiologic 过程, DNA, RNA,蛋白质,或代谢物的另外的面板正在被探索。未来冒险将需要继续数据集成和确认让临床上有用的不孕 biomarkers 的开发帮助男不孕诊断,处理,并且建议。 | Jared M Bieniek Andrei P Drabovich Kirk C Lo | 2016 | Asian Journal of Andrology2016，18，3： | 15 |
| 6 | Platelet thromboxane(11-dehydro-Thromboxane B_2) and aspirin response in patients with diabetes and coronary artery disease显示文摘Aspirin(ASA) irreversibly inhibits platelet cyclooxygenase-1(COX-1) leading to decreased thromboxane-mediated platelet activation. The effect of ASA ingestion on thromboxane generation was evaluated in patients with diabetes(DM) and cardiovascular disease. Thromboxane inhibition was assessed by measuring the urinary excretion of 11-dehydro-thromboxane B2(11dhTxB2), a stable metabolite of thromboxane A2. The mean baseline urinary 11dhTxB2 of DM was 69.6% higher than healthy controls(P = 0.024): female subjects(DM and controls) had 50.9% higher baseline 11dhTxB2 than males(P = 0.0004), while age or disease duration had no influence. Daily ASA ingestion inhibited urinary 11dhTxB2 in both DM(71.7%) and controls(75.1%, P < 0.0001). Using a pre-established cut-off of 1500 pg/mg of urinary 11dhTxB2, there were twice as many ASA poor responders(ASA 'resistant') in DM than in controls(14.8% and 8.4%, respectively). The rate of ASA poor responders in two populations of acute coronary syndrome(ACS) patients was 28.6 and 28.7%, in spite of a significant(81.6%) inhibition of urinary 11dhTxB2(P < 0.0001). Both baseline 11dhTxB2 levels and rate of poor ASA responders were significantly higher in DM and ACS compared to controls. Underlying systemic oxidative inflammation may maintain platelet function in atherosclerotic cardiovascular disease irrespective of COX-1 pathway inhibition and/or increase systemic generation of thromboxane from non-platelet sources. | Luis R Lopez Kirk E Guyer Ignacio Garcia De La Torre Kelly R Pitts Eiji Matsuura Paul RJ Ames | 2014 | World Journal of Diabetes2014，5，2： | 13 |
| 7 | 铅冶炼污染区小麦籽粒镉含量及低积累品种筛选显示文摘从已有研究看,小麦属于对土壤重金属有较强积累能力的作物,土壤重金属污染区易发生小麦籽粒镉超标现象[1-4]。本研究选择100个小麦品种或品系(其中品种88个,品系为12个),在河南省西北部某铅污染农田中种植,收获后测定籽粒镉含量,以评判河南省铅冶炼污染区小麦籽粒镉积累现状并选出对镉积累程度较低的小麦品种。田间试验于2013年10月到2014年6月间进行。研究区地形为山前平原,海拔约250 m。 | 邢维芹 张红毅 Kirk G.Scheckel 吴龙华 李会勇 Aaron R.Betts 周通 李向东 卢一富 田会阳 李立平 | 2015 | 农业环境科学学报2015，34，10： | 13 |
| 8 | 迷宫密封结构对泄漏量和轴系临界转速影响分析研究显示文摘运用数值方法对转子-轴承-密封系统动力学模型求解,对3种密封间隙、8种密封直径、8种压差、8种入口损失率和21种密封长度对泄漏量和临界转速的影响进行研究;通过密封结构对轴系临界转速影响规律进行研究,对比分析了有、无密封力作用下转子-轴承-密封系统对临界转速影响。研究结果表明:通过与DYNLAB程序、TASCFlow程序的结果对比分析,该数学模型能较好的模拟计算泄漏量和转子系统临界转速;通过对泄漏量影响规律研究,得出泄漏量随着密封间隙、密封直径和密封长度做增大而增大,泄漏量随压差和入口损失率的增大而减小。通过对临界转速影响规律研究,得到考虑密封会提高临界转速,密封长度的变化对临界转速的影响最大、密封间隙的变化对临界转速影响最小。 | 马文生 陈照波 焦映厚 R G Kirk | 2013 | 振动工程学报2013，26，6： | 12 |
| 9 | 基质辅助激光解吸电离飞行时间质谱技术在临床微生物鉴定中的应用显示文摘近年来,基质辅助激光解吸电离飞行时间质谱技术(MALDI—TOF—MS)已从物理实验室走进临床微生物实验室,用于微生物的鉴定,正逐步取代由Pasteur和Koch建立的基于细菌表型的传统鉴定方法。许多欧洲微生物实验室目前正在使用MALDI-TOF-MS,大大提高了工作效率。鉴于美国食品药品管理局已经批准其用于体外诊断,MALDI-TOF-MS将很快在美国普及应用。这也将进一步推动了质谱技术在微生物药敏和流行学分型中的发展和应用。本文综述了MALDI—TOF—MS在临床微生物实验室的应用现状,并通过多中心临床试验结果,比较不同MALDI—TOF-MS仪器获得的诊断数据,重点阐述其在临床微生物领域的相关研究和应用。 | Marc van Nuenen Kirk Doing 顾兵 Alex van Belkum | 2015 | 中华检验医学杂志2015，38，1： | 11 |
| 10 | 转速数对滑动轴承动力学系数影响研究显示文摘建立了滑动轴承的基于短轴承非线性油膜力模型,通过转速对轴承动力学特性的影响研究,得到了偏心率、最小油膜厚度、最大油膜压力、摩擦功耗、温升、临界轴颈质量、刚度系数、阻尼系数、二维和三维油膜压力的影响因素研究;在对三维油膜压力分析时发现转速存在一个临界值,当转速低于这个临界值时,转速对最大油膜压力影响较大,当转速高于这个临界值时,转速对最大油膜压力影响不大。 | 马文生 陈照波 焦映厚 Kirk R G | 2014 | 振动与冲击2014，33，5： | 11 |
| 11 | Effects of ghrelin on interdigestive contractions of the rat gastrointestinal tract显示文摘Ghrelin causes interdigestive contractions of the stom- ach in rats. However, it remains unknown whether ghrelin causes interdigestive contractions in the small intestine. Four strain gauge transducers were implanted on the antrum, duodenum, proximal and distal jejunum. After an overnight fast, gastrointestinal (GI) contrac- tions were recorded in freely moving conscious rats. Spontaneous phase Ⅲ-like contractions were observed at every 13-16 min in rat GI tract. The fasted motor patterns were replaced by the fed motor pattern immediately after food intake. Two minutes after f inishing the spontaneous phase Ⅲ-like contractions in the antrum, acyl ghrelin (0.8, 2.4 and 8.0 μg/kg per min) was con- tinuously infused for 30 min. Three-f ive minutes after the starting ghrelin infusion, augmented phase Ⅲ-like contractions were observed at the antrum, duodenum, and jejunum. Ghrelin infusion (0.8, 2.4 and 8.0 μg/kg per min) signif icantly increased motility index of phase Ⅲ-like contractions at the antrum and jejunum in a dose dependent manner, compared to that of saline in- jection. Thus, it is likely that exogenously administered ghrelin causes phase Ⅲ-like contraction at the antrum, which migrates to the duodenum and jejunum. The possible role of 5-HT, in addition to ghrelin, in mediating intestinal migrating motor complex (MMC), is discussed. | Hiroshi Taniguchi Hajime Ariga Kirk Ludwig Toku Takahashi | 2008 | World Journal of Gastroenterology2008，14，41： | 10 |
| 12 | 不同阴离子对水溶性磷酸盐稳定污染土壤中重金属的影响显示文摘在重金属污染土壤中加入磷酸盐是稳定重金属的有效方法.本研究的目的是探讨不同阴离子对水溶性磷酸盐稳定污染土壤铅、镉和锌的影响.在重金属复合污染土壤(全铅、镉和锌的含量分别为2337、21.4和391 mg·kg-1)中按P∶Pb=2∶1(mol∶mol)加入磷酸二氢钙,之后按P∶阴离子=3∶1或3∶2(mol∶mol)加入盐酸、氯化钠、硫酸、硫酸钠或氟化钠,并设置只加磷酸盐、不加其它试剂的对照,培养55 d,之后测定土壤性质.结果表明,与对照相比,HCl处理、2HCl处理、NaCl处理和2NaCl处理土壤DTPA-Pb含量下降比例依次为5.72%、9.29%、6.38%和8.80%(p〈0.05),加入硫酸、硫酸钠的处理土壤DTPA-Pb含量与对照无显著差异(p〉0.05),而加入氟化钠的处理升高4.70%(p〈0.05).加入盐酸或氯化钠的处理土壤镉有效性显著高于对照(升高5.24%~12.8%)(p〈0.05),其它处理对DTPA-Cd含量无显著影响(p〉0.05).各处理对土壤DTPA-Zn含量和pH影响较小,但均引起土壤电导率明显升高.以上结果表明,氯离子可促进水溶性磷酸盐对土壤铅的稳定,但可促进镉有效性.氯磷酸铅的生成是加氯情况下磷酸盐稳定铅的重要机制. | 邢维芹 王亚利 Kirk G Scheckel 李立平 向国强 巩丹丹 史丽兰 | 2013 | 环境科学学报2013，33，10： | 10 |
| 13 | Genotyping-by-sequencing of pear (Pyrus spp.) accessions unravels novel patterns of genetic diversity and selection footprints显示文摘Understanding of genetic diversity and marker-trait relationships in pears(Pyrus spp.)forms an important part of gene conservation and cultivar breeding.Accessions of Asian and European pear species,and interspecific hybrids were planted in a common garden experiment.Genotyping-by-sequencing(GBS)was used to genotype 214 accessions,which were also phenotyped for fruit quality traits.A combination of selection scans and association analyses were used to identify signatures of selection.Patterns of genetic diversity,population structure and introgression were also investigated.About 15000 high-quality SNP markers were identified from the GBS data,of which 25%and 11%harboured private alleles for European and Asian species,respectively.Bayesian clustering analysis suggested negligible gene flow,resulting in highly significant population differentiation(Fst=0.45)between Asian and European pears.Interspecific hybrids displayed an average of 55%and 45%introgression from their Asian and European ancestors,respectively.Phenotypic(firmness,acidity,shape and so on)variation between accessions was significantly associated with genetic differentiation.Allele frequencies at large-effect SNP loci were significantly different between genetic groups,suggesting footprints of directional selection.Selection scan analyses identified over 20 outlier SNP loci with substantial statistical support,likely to be subject to directional selection or closely linked to loci under selection. | Satish Kumar Chris Kirk Cecilia Deng Claudia Wiedow Mareike Knaebel Lester Brewer | 2017 | Horticulture Research2017，4，1： | 8 |
| 14 | 不同添加剂对铅冶炼污染石灰性土壤的修复及土壤性质的影响研究显示文摘探讨了污水处理厂脱水污泥、枯草和磷矿粉对受铅冶炼污染的石灰性土壤(全Pb、Cd、Zn含量分别为2337、21.4、486 mg·kg-1,DTPA提取态Pb、Cd、Zn含量分别为1035、14.5、68.7 mg·kg-1)中重金属的稳定效果及对土壤性质的影响.其中,污泥和枯草均按200 g·kg-1(干重)的用量施用,磷矿粉按n(P)∶n(Pb)=2∶1比例施用,培养80 d.研究结果表明,单独施用污泥可使土壤DTPA-Pb含量降低18.0%(p<0.05),并可显著降低土壤pH,增加土壤氮、磷有效性和电导率、DTPA-Cd、DTPA-Zn含量,其中,DTPA-Cd、DTPA-Zn含量增加比例均达到10%以上.单独施用枯草可使土壤DTPA-Pb含量降低10.7%(p<0.05),土壤有机质含量增加26.4%(p<0.05),对土壤其它性状影响较小.磷矿粉单独施用时对土壤性质影响较小.与污泥单独施用相比,磷矿粉与污泥配合施用时,可使土壤DTPA-Cd含量降低11.9%. | 邢维芹 历琳 Kirk G.Scheckel Aaron R.Betts 向国强 兰欢 李立平 | 2014 | 环境科学学报2014，34，6： | 7 |
| 15 | 偏心率和转速对迷宫密封力和动力学参数影响分析研究显示文摘通过数值方法和商用CFD(计算流体动力学)软件对密封-转子系统进行建模和求解,研究了5种偏心率和5种转速下的计算机求解时间、流场压力分布、密封力的变化情况,并对泄漏量影响分析和迷宫密封动力学参数影响进行分析研究。研究结果表明:该方法能较好地模拟计算迷宫密封泄漏量和动力学参数,得到腔室压力随着偏心率增大而增大,密封切向力随着偏心率、转速的增大而增大,密封径向力随着偏心率、转速的增大而负向增大;通过密封长度、密封间隙、密封压差对泄漏量影响计算,三者变化率分别为6.62%,65.21%和69.97%,表明密封间隙和压差变化是影响泄漏量变化的重要影响因素;通过密封压差和密封长度对动力学参数影响分析,得出增大密封压差和密封长度不利于系统稳定、增大密封间隙会使得系统趋于稳定。 | 马文生 陈照波 焦映厚 R G Kirk | 2012 | 振动工程学报2012，25，3： | 7 |
| 16 | Final anatomic and visual outcomes appear independent of duration of silicone oil intraocular tamponade in complex retinal detachment surgery显示文摘AIM: To report anatomic and visual outcomes following silicone oil removal in a cohort of patients with complex retinal detachment, to determine association between duration of tamponade and outcomes and to compare patients with oil removed and those with oil in situ in terms of demographic, surgical and visual factors. METHODS: We reported a four years retrospective case series of 143 patients with complex retinal detachments who underwent intraocular silicone oil tamponade. Analysis between anatomic and visual outcomes, baseline demographics, duration of tamponade and number of surgical procedures were carried out using Fisher's exact test and unpaired two-tailed t-test. RESULTS: One hundred and six patients(76.2%) had undergone silicone oil removal at the time of review with 96 patients(90.6%) showing retinal reattachment following oil removal. Duration of tamponade was not associated with final reattachment rate or with a deterioration in best corrected visual acuity(BCVA). Patients with oil removed had a significantly better baseline and final BCVA compared to those under oil tamponade(P=0.0001, <0.0001 respectively). CONCLUSION: Anatomic and visual outcomes in this cohort are in keeping with those reported in the literature. Favorable outcomes were seen with oil removal but duration of oil tamponade does not affect final attachment rate with modern surgical techniques and should be managed on a case by case basis. | Maedbh Rhatigan Elizabeth Mc Elnea Patrick Murtagh Kirk Stephenson Elaine Harris Paul Connell David Keegan | 2018 | International Journal of Ophthalmology(English edition)2018，11，1： | 7 |
| 17 | FeCl_2处理电炉炉尘的热力学计算显示文摘电炉炉尘中富含Zn、Pb、Cd等元素,简单地将这些炉尘倾倒野外或填埋,Pb、Cd等重金属元素的浸出会污染环境 ,而直接将炉尘返回钢铁厂内循环使用 ,Zn在高炉内富集会缩短炉衬寿命 ,而且这些元素向钢水的转移还会降低钢材品质。为减少电炉炉尘对环境的污染和实现其综合利用 ,必须寻求经济高效的新方法脱除炉尘中Zn、Pb、Cd等有害元素。通过热力学计算分析了采用FeCl_2去除电炉炉尘中Zn、Pb的可能性 ,比较了不同反应条件下的作用效果。计算结果表明,在 600~900℃下,炉尘中ZnO、ZnFe_2O_4 、CuO、PbO和CdO几乎全部转化为气相氯化物。对于CaO含量较高的炉尘 ,添加SiO2 有利于提高炉尘中有害元素的脱除效率,Zn的脱除率约 96 %~ 98%。当反应温度超过950℃。 | 王谦 J W Graydon D W Kirk | 2003 | 重庆大学学报(自然科学版)2003，26，6： | 7 |
| 18 | 添加剂对伴矿景天修复石灰性铅冶炼污染土壤的影响显示文摘为了探讨利用伴矿景天(Sedum plumbizincicola)修复北方重金属污染土壤的可行性,在河南省某铅冶炼形成的污染农田(全镉、铅和锌含量分别为2.65、261和130 mg·kg-1)上种植种子苗或扦插苗伴矿景天,并设对照(CK)、单独尿素(U)、尿素和单质硫(U+S)、尿素与鸡粪(U+CM)配合处理,生长7个月后采样分析.结果表明,种子苗产量比扦插苗高45.8%~162.0%,U、U+CM处理产量均明显高于CK,而U+S处理产量有所下降.种子苗地上部镉含量比扦插苗高15%~99%(p<0.05),多数处理铅和锌含量也是种子苗高于扦插苗.与CK相比,各处理措施均导致伴矿景天地上部镉和铅含量下降,而U+S、U+CM处理均导致伴矿景天地上部锌含量上升.从伴矿景天地上部重金属积累量判断,与CK相比,对于镉,仅种子苗U+CM处理镉积累量有所上升;U处理种子苗和扦插苗地上部锌积累量分别比CK上升43.5%和32.3%,两种苗U+S处理锌积累量比CK分别上升11.1%和22.3%.种子苗和扦插苗地上部镉的积累量分别为137~178 g·hm-2和43.7~64.8 g·hm-2,锌的积累量分别为297~1042 g·hm-2和162~326 g·hm-2,两类苗对铅的积累量小于28.8 g·hm-2.U+CM处理对伴矿景天地上部锌吸收的促进作用主要是由于鸡粪中含有大量的有效锌.以上结果表明,可利用种子苗伴矿景天结合尿素的施用对铅冶炼污染石灰性土壤进行修复. | 李立平 田会阳 卢一富 张红毅 吴龙华 Kirk G.Scheckel 邢维芹 | 2015 | 环境科学学报2015，35，6： | 6 |
| 19 | Emergency department procedural sedation for primary electrical cardioversion — a comparison with procedural sedations for other reasons显示文摘BACKGROUND: Atrial fibrillation(AF) is the most common arrhythmia treated in the emergency department(ED), with primary electrical cardioversion(PEC) the preferred method of rhythm control. Anecdotally, patients undergoing ED procedural sedation(EDPS) for PEC differ from those requiring EDPS for other procedures: they are at higher risk of adverse events, and require fewer drugs and lower doses. We attempt to verify this using an EDPS registry at a Canadian, tertiary care teaching hospital.METHODS: This is a retrospective review of patients that underwent EDPS for the period of June 2006 to September 2014. We compared demographics, medication use and intra-procedural adverse events between those receiving EDPS for PEC for AF compared to that for other indications. We report the asssociation between AEs and predictors using logistic regression.RESULTS: A total of 4 867 patients were included, 714 for PEC for AF and 4 153 for other indications. PEC patients were more likely male(58.5% vs. 47.1%), older(59.5 years vs. 48.1 years), and less likely to be ASA I(46.6% vs. 69.0%). PEC patients received smaller doses of propofol and less likely to receive adjuvant analgesic therapy(11.5% vs. 78.2%). PEC patients were more likely to experience hypotension(27.6% vs. 16.5%) but respiratory AEs(apnea, hypoxia and airway intervention) were not different.CONCLUSION: EDPS for PEC differs from that conducted for other purposes: patients tend to be less healthy, receive smaller doses of medication and more likely to suffer hypotension without an increase in respiratory AEs. These factors should be considered when performing EDPS. | Michael Butler Patrick Froese Peter Zed George Kovacs Robert Mac Kinley Kirk Magee Mary-Lynn Watson Samuel G.Campbell | 2017 | World Journal of Emergency Medicine2017，8，3： | 6 |
| 20 | 生物技术与制浆造纸工业(下)显示文摘文章就生物技术在制浆造纸工业的应用现况及其前景,作出综述。文章涉及的三个主要方面包括导致木素降解的真菌体系及其应用,多糖类降解体系及其利用,以及其他体系的生物技术。在论述中,特别注意到介绍可望在中国应用的某些最新成果。 | 张厚民 Kirk,TK | 1994 | 中国造纸1994，13，5： | 5 |
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