|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Effect of Astragalus polysaccharides on Erythrocyte Immune Adherence of Chickens Inoculated with Infectious Bursal Disease Virus显示文摘Two hundred and forty specific pathogen free leghorn chickens were randomly divided into four groups and reared in isolated pens. The tested chickens were negative to infectious bursal disease virus (IBDV) at 25 d old. Group 1 was treated with saline,whereas Groups 2,3,and 4 were inoculated with 0.3 mL IBDV suspension intranasally the next day. Groups 3 and 4 were also administered with Astragalus polysaccharides (APS) intramuscularly twice daily at 5 or 10 mg kg-1 BW,respectively,until 31 d old. The erythrocyte-C3b receptor rosette rate (E-C3bRR) and the erythrocyte-C3b immune complex rosette rate (E-ICRR) were measured at 25,29,32,35,and 38 d old. The results showed that IBDV significantly reduced E-C3bRR and E-ICRR when compared with the control group (P < 0.05),while simultaneous administration of APS with IBDV maintained E-C3bRR at similar levels to the control group (P > 0.05) and increased E-ICRR when compared with the control group and the group non-treated with APS (P < 0.05). APS treatment reduced the morbidity and mortality of chickens inoculated with IBDV (P < 0.05). The results suggest that APS may enhance the immune adherence of chickens erythrocytes by affecting the activity and/or the number of complement receptors on the erythrocyte membrane. These findings can be beneficial in providing an understanding of the basic mechanisms required for the rational application of APS in modern medicine. | LI Hong-quan Lloyd Reeve-Johnson WANGJun-dong | 2007 | Agricultural Sciences in China2007，6，11： | 21 |
| 2 | Whole brain radiotherapy for the treatment of multiple brain metastases显示文摘 | Tsao M Lloyd N Wong R Chow E Rakovitch E Laperriere N | 2006 | 中国神经肿瘤杂志2006，4，2： | 17 |
| 3 | More anxious than depressed:prevalence and correlates in a 15-nation study of anxiety disorders in people with type 2 diabetes mellitus显示文摘Background Anxiety disorder, one of the highly disabling, prevalent and common mental disorders, is known to be more prevalent in persons with type 2 diabetes mellitus (T2DM) than the general population, and the comorbid presence of anxiety disorders is known to have an impact on the diabetes outcome and the quality of life. However, the information on the type of anxiety disorder and its prevalence in persons with T2DM is limited. Aims To assess the prevalence and correlates of anxiety disorder in people with type 2 diabetes in different countries. Methods People aged 18-65 years with diabetes and treated in outpatient settings were recruited in 15 countries and underwent a psychiatric interview with the Mini-International Neuropsychiatric Interview. Demographic and medical record data were collected. Results A total of 3170 people with type 2 diabetes (56.2% women;with mean (SD) duration of diabetes 10.01 (7.0) years) participated. The overall prevalence of anxiety disorders in type 2 diabetic persons was 18%;however, 2.8% of the study population had more than one type of anxiety disorder. The most prevalent anxiety disorders were generalised anxiety disorder (8.1%) and panic disorder (5.1%). Female gender, presence of diabetic complications, longer duration of diabetes and poorer glycaemic control (HbA1c levels) were significantly associated with comorbid anxiety disorder. A higher prevalence of anxiety disorders was observed in Ukraine, Saudi Arabia and Argentina with a lower prevalence in Bangladesh and India. Conclusions Our international study shows that people with type 2 diabetes have a high prevalence of anxiety disorders, especially women, those with diabetic complications, those with a longer duration of diabetes and poorer glycaemic control. Early identification and appropriate timely care of psychiatric problems of people with type 2 diabetes is warranted. | Santosh K Chaturvedi Shayanth Manche Gowda Helal Uddin Ahmed Fahad D Alosaimi Nicola Andreone Alexey Bobrov Viola Bulgari Giuseppe Carra Gianluca Castelnuovo Giovanni de Girolamo Tomasz Gondek Nikola Jovanovic Thummala Kamala Andrzej Ki Nebojsa Lalic Dusica Lecic-Tosevski Fareed Minhas Victoria Mutiso David Ndetei Golam Rabbani Suntibenchakul Somruk Sathyanarayana Srikanta Rizwan Taj Umberto Valentini Olivera Vukovic Wolfgang Wolwer Larry Cimino Arie Nouwen Cathy Lloyd Norman Sartorius | 2019 | General Psychiatry2019，32，4： | 11 |
| 4 | The yin and yang of co-inhibitory receptors: toward anti-tumor immunity without autoimmunity显示文摘Co-inhibitory receptors are important regulators of T | Alexandra Schnell Lloyd Bod Asaf Madi Vijay K.Kuchroo | 2020 | Cell Research2020，30，4： | 10 |
| 5 | Canadian Agility and Movement Skill Assessment(CAMSA):Validity, objectivity, and reliability evidence for children 8–12 years of age显示文摘Purpose: The primary aim of this study was to develop an assessment of the fundamental, combined, and complex movement skills required to support childhood physical literacy. The secondary aim was to establish the feasibility, objectivity, and reliability evidence for the assessment.Methods: An expert advisory group recommended a course format for the assessment that would require children to complete a series of dynamic movement skills. Criterion-referenced skill performance and completion time were the recommended forms of evaluation. Children, 8–12 years of age, self-reported their age and gender and then completed the study assessments while attending local schools or day camps. Face validity was previously established through a Delphi expert(n = 19, 21% female) review process. Convergent validity was evaluated by age and gender associations with assessment performance. Inter-and intra-rater(n = 53, 34% female) objectivity and test–retest(n = 60, 47% female) reliability were assessed through repeated test administration.Results: Median total score was 21 of 28 points(range 5–28). Median completion time was 17 s. Total scores were feasible for all 995 children who self-reported age and gender. Total score did not differ between inside and outside environments(95% confidence interval(CI) of difference:-0.7 to 0.6;p = 0.91) or with/without footwear(95%CI of difference:-2.5 to 1.9; p = 0.77). Older age(p < 0.001, η2= 0.15) and male gender(p < 0.001, η2= 0.02)were associated with a higher total score. Inter-rater objectivity evidence was excellent(intraclass correlation coefficient(ICC) = 0.99) for completion time and substantial for skill score(ICC = 0.69) for 104 attempts by 53 children(34% female). Intra-rater objectivity was moderate(ICC = 0.52) for skill score and excellent for completion time(ICC = 0.99). Reliability was excellent for completion time over a short(2–4 days; ICC = 0.84) or long(8–14days; ICC = 0.82) interval. Skill score reliability was moderate(ICC = 0.46) over a short interval, and substantial(ICC = 0.74) over a long interval.Conclusion: The Canadian Agility and Movement Skill Assessment is a feasible measure of selected fundamental, complex and combined movement skills, which are an important building block for childhood physical literacy. Moderate-to-excellent objectivity was demonstrated for children 8–12 years of age. Test–retest reliability has been established over an interval of at least 1 week. The time and skill scores can be accurately estimated by 1 trained examiner. | Patricia E.Longmuir Charles Boyer Meghann Lloyd Michael M.Borghese Emily Knight Travis J.Saunders Elena Boiarskaia Weimo Zhu Mark S.Tremblay | 2017 | Journal of Sport and Health Science2017，6，2： | 10 |
| 6 | Enhancing the accuracy of area extraction in machine vision-based pig weighing through edge detection显示文摘The accuracy of extracting projected pig area is critical to the accuracy of the weight measurement of pigs by machine vision.The capability of both the conventional and the edge detection methods for extracting pig area was examined using the images of 47 pigs of different weights.Relationship between the threshold value and the extracted area was numerically analyzed for both methods.It was found that the accuracy of the conventional method depended heavily on the threshold value,while choice of threshold value in the edge detection approach had no influence on the extracted area over a wide range.In normal lighting conditions,both methods yielded comparable values of predicted weight;however,under variable light intensities,the edge detection method was superior to the conventional method,because the former was proven to be independent of light intensities.This makes edge detection an ideal method for area extraction during the walk-through weighing process where pigs are allowed to move around. | Yongsheng Wang Wade Yang Lloyd T.Walker Taha M.Rababah | 2008 | International Journal of Agricultural and Biological Engineering2008，1，1： | 9 |
| 7 | Characterization of the Formation of Branched Short-Chain Fatty Acid:CoAs for Bitter Acid Biosynthesis in Hop Glandular Trichomes显示文摘痛苦的酸,作为啤酒香料并且为他们的多样的生物活动为他们的使用知道,主要 formedin 跳跃(Humulus lupulus ) 腺的毛状体。分叉的短链的 acyl-CoAs (例如 isobutyryl-CoA, isovaleryl-CoA 和 2-methylbutyryl-CoA ) , derivedfrom 分支链氨基酸(BCAA ) 的降级,为痛苦的 acidsin 的生合成的必要积木跳跃。然而,很少关于部件被需要生产并且维持分叉的 short-chainacyl-CoAs 的水池在的被知道跳跃毛状体。这里,我们在场 CoA ligases 和 thioesterases 是在痛苦的酸生合成的 likelyinvolved 的证据的几根线。蛋白质有的 Recombinant HlCCL2 ( carboxyl CoA ligase )为象底层酸的 isovaleric 的高特定的活动( K 猫 /K m = 4100 s 1 M 1),而 recombinant HlCCL4 明确地利用了 isobutyric 酸( K 猫 /K m = 1800 s 1 M 1)并且 2-methylbutyric 酸( K 猫 /K m = 6900 s 1 M 1)作为底层。两 HlCCLs 跳跃 valerophenone synthase (HlVPS ) ,在腺的毛状体强烈被表示并且对细胞质局部性。有在酵母的 HlVPS 的 HlCCL2 和 HlCCL4 的合作表示导致了 acylphloroglucinols (为痛苦的酸生合成的直接先锋) 的重要生产, whichfurther 在 vivo 证实了这二 HlCCLs 的生物化学的功能。在线粒体催化 CCL 的反向的反应的 thioesterase 的功能的鉴定,和 thecomprehensive,基因的分析包含了 BCAA 分解代谢,支持了 cytosolic CoA ligases 在腺的毛状体为 linkingBCAA 降级和痛苦的酸生合成被要求的想法。进化和另外的可能的生理的 rolesof 分叉短链的丰满的酸: 在 planta 的 CoA ligases 也是 discussed.Key 词: | Haiyang Xu Fengxia Zhang Baoxiu Liu David V. Huhman Lloyd W. Sumner Richard A. Dixon Guodong Wang | 2013 | Molecular Plant2013，6，4： | 9 |
| 8 | 美国花生脱壳机研究现状及发展分析显示文摘脱壳是花生利用前必经环节,脱壳机是花生产后加工的核心设备,在很大程度上决定了花生的果仁质量和脱壳效率。中国虽然花生产量位居世界第一,且花生脱壳机得到广泛应用,但花生脱壳技术远不及美国,严重制约花生产后加工业的发展。为借鉴美国花生脱壳技术及发展经验,在实地考察基础上,运用社会调查法、文献研究法和经验总结等方法,本文分析了美国花生脱壳机的发展历史、最新进展和技术衍变过程,剖析了美国现代花生脱壳机的脱壳原理、总体构成、脱壳部件结构型式和特点,总结了美国花生脱壳技术研究的基本方法和成功经验。结果显示,美国花生脱壳机研究密切结合生产需要,起步早且不断创新;多滚筒大型脱壳机既可用于榨油和食品加工的花生脱壳,也可用于种子花生脱壳,各滚筒之间独立驱动,转速200~300 r/min;脱壳机构由带有刮板的脱壳打杆和钢制栅片凹板筛构成,对花生荚果进行刮搓脱壳;复式清选装置首先进行气吸除壳、然后进行筛选和二次气吸清选。美国花生脱壳机技术是机械与农艺等多方面融合研究的结果,对中国花生脱壳技术研究及进展具有重要借鉴意义。 | 陆荣 刘志侠 高连兴 CHEN Charles BUTTS Christopher Lloyd | 2020 | 华中农业大学学报2020，39，2： | 6 |
| 9 | Arabidopsis Mutants and the Network of M icrotu bu le-Associated Functions显示文摘在早优核质,微导管系统从事有丝分裂,细胞内部的运输,和基于鞭子的活动性。在植物系,多细胞的身体的进化包含了一些核心函数,其它的损失,和与多细胞的植物习惯联系的新微导管函数的详尽阐述的保存。这多样化被保存的两个(animal/fungi-like ) 和小说的存在反映(似植物) 把微导管相关的功能编码为 Arabidopsis 染色体的序列。微导管异种的收集在最近的年很快成长了。这些异种介绍大量显型,与微导管系统的功能的多样化的假设一致。在这评论,我们集中于变异的分析并且特别地,为指出基因功能的小径作为一个珍贵工具讨论两倍变异的分析。未来挑战将是在植物定义微导管功能的基因、物理的相互作用的完全的网络。除了在 MAPome 的功能的分析考察最近的进步,我们在场在微导管损害的 Arabidopsis 异种的一个联机数据库工作。 | Henrik Buschmann Clive W. Lloyd | 2008 | Molecular Plant2008，1，6： | 6 |
| 10 | Mass Spectrometric Analyses Reveal a Central Role for Ubiquitylation in Remodeling the Arabidopsis Proteome during Photomorphogenesis显示文摘 | Victor Aguilar-Hernandez Do-Young Kim Robert J. Stankey Mark Scalf Lloyd M. Smith Richard D. Vierstra | 2017 | Molecular Plant2017，10，6： | 6 |
| 11 | Maintenance infliximab for Crohn’s disease: the ACCENT I randomised trial显示文摘 | Stephen B Hanauer Brian G Feagan Gary R Lichtenstein Lloyd F Mayer S Schreiber Jean Frederic Colombel Daniel Rachmilewitz Douglas C Wolf Allan Olson Weihang Bao Paul Rutgeerts | 2002 | The Lancet2002，，9317： | 6 |
| 12 | 选择“货到人”技术的考虑要素显示文摘无论用什么技术和方式把货物送到拣选者身边,其主要目的是为了减少操作人员的移动时间.研究表明,拣选者大约70%的时间用在了移动上,实际上只有30%的时间在挑选产品.因此,采用“货到人”技术节省了移动时间,从而大大提高了拣选者的工作效率. | Lloyd Morgan 朱凌 | 2015 | 物流技术与应用2015，4，10： | 5 |
| 13 | Randomized Trial Evaluating Ranibizumab Plus Prompt or Deferred Laser or Triamcinolone Plus Prompt Laser for Diabetic Macular Edema显示文摘 | Michael J. Elman Lloyd Paul Aiello Roy W. Beck Neil M. Bressler Susan B. Bressler Allison R. Edwards Frederick L. Ferris Scott M. Friedman Adam R. Glassman Kellee M. Miller Ingrid U. Scott Cynthia R. Stockdale Jennifer K. Sun | 2010 | Ophthalmology2010，，6： | 5 |
| 14 | 多种癌-睾丸抗原基因在术前化疗非小细胞肺癌中的表达显示文摘目的 研究癌 睾丸抗原 (CT)抗原在经术前化疗的非小细胞肺癌 (NSCLC)中的表达谱 ,以确定NSCLC经化疗、手术后可能的辅助免疫治疗疫苗治疗组成成分。方法 用逆转录 聚合酶链反应 (RT PCR)检测了 5 1例经化疗后手术的原发性NSCLC病人肿瘤组织中 11种CT抗原基因的表达情况。结果 所检测的 11种CT基因在经化疗后的NSCLC表达最高的为MAGE 3,38% ,其次分别为NY ESO 12 1% ,CT10 17% ,LAGE 115 % ,MAGE 4 13% ,SCP 1、SSX1、SSX4均为 12 % ,MAGE 110 % ,SSX2 6 % ,CT72 %。在这些病人中 ,有 34例 (6 7% )病人表达至少 1种CT基因。在不表达所检测的任何CT基因的 17例病人中 ,13例 (76 % )为Ⅰ期病人。MAGE 3和CT10在NSCLC中表现出了随疾病进展而增加的现象 ;反之 ,SCP 1的表达主要在Ⅰ期和Ⅱ期。将NSCLC经病理分类分为鳞癌和腺癌 ,发现鳞癌中至少表达 1种CT基因 (75 % )和共表达CT基因的频率 (5 5 % )均比腺癌 (5 3%和 2 4 % )高。结论 (1)包括MAGE 3、NY ESO 1、LAGE 1等抗原成分的CT抗原疫苗可应用于术前化疗的NSCLC病人的治疗 ;(2 )对不同NSCLC肿瘤分期的病人可采取不同CT抗原成分疫苗 ;(3)对晚期手术和化疗疗效不好的病人和鳞癌病人 ,CT抗原疫苗治疗是一个值得研究的重要方向。 | 王歈 梁震 袁艳华 韩燕 刘月香 刘年 Yao-Tseng Chen Gerd Ritter Lloyd J Old 张力建 | 2004 | 中华医学杂志2004，84，6： | 4 |
| 15 | Imaging of liver cancer显示文摘Improvements in imaging technology allow exploitation of the dual blood supply of the liver to aid in the identif ication and characterisation of both malignant and benign liver lesions. Imaging techniques available include contrast enhanced ultrasound, computed tomography and magnetic resonance imaging. This review discusses the application of several imaging techniques in the diagnosis and staging of both hepatocellular carcinoma and cholangiocarcinoma and outlines certain characteristics of benign liver lesions. The advantages of each imaging technique are highlighted, while underscoring the potential pitfalls and limitations of each imaging modality. | Ben Ariff Claire R Lloyd Sameer Khan Mohamed Shariff Andrew V Thillainayagam Devinder S Bansi Shahid A Khan Simon D Taylor-Robinson Adrian KP Lim | 2009 | World Journal of Gastroenterology2009，15，11： | 4 |
| 16 | 门诊烧伤的预防与治疗显示文摘大多数烧伤可由初级保健医生在门诊实施治疗。加强预防可使烧伤发生率明显下降,特别对儿童而言。与其他创伤管理相似,烧伤管理包括初级和次级评估。处理浅度烧伤可采用药液、蜂蜜、芦荟或抗生素软膏局部用药。部分皮层烧伤局部用抗菌药物或吸收性封闭敷料有助于减少疼痛、促进愈合和防止创面干燥。 | Emillia CO Lloyd Blake C Rodgers 周淑新(译) 葛军(译) | 2013 | 中国全科医学2013，16，9： | 3 |
| 17 | 高危心血管病老年人血压变异性的相关因素显示文摘诊问血压变异性是心血管病的独立预测因素。该研究探讨老年人血压变异的相关因素。方法:在普伐他汀干预高危老年人的前瞻性研究( pravastatin inelderly individuals at risk of vascular disease, PROS-PER)中,分析70~82岁有心血管病史或危险因素的男性和女性者3794人。 | Poortvliet RK Lloyd SM Ford I Sattar N de Craen AJ Wijsman LW Mooijaart SP Westendorp G Jukema JW de Ruijter W Gussekloo J Stott DJ | 2015 | 中华高血压杂志2015，23，10： | 3 |
| 18 | The synthetic form of a novel chicken β-defensin identified in silico is predominantly active against intestinal pathogens显示文摘 | Rowan Higgs David J. Lynn Susan Gaines Jessica McMahon Joanna Tierney Tharappel James Andrew T. Lloyd Grace Mulcahy Cliona O’Farrelly | 2005 | Immunogenetics (-)2005，，1： | 3 |
| 19 | The Three Es of Cancer Immunoediting显示文摘 | Gavin P. Dunn Lloyd J. Old Robert D. Schreiber | 2004 | Annual Review of Immunology2004，，： | 3 |
| 20 | Applications and opportunities for ultrasound assisted extraction in the food industry — A review显示文摘 | Kamaljit Vilkhu Raymond Mawson Lloyd Simons Darren Bates | 2007 | Innovative Food Science and Emerging Technologies2007，，2： | 3 |
您所在的机构暂未开通此部分的功能，请联系管理员