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| 1 | Drying characteristics and quality of bananas under infrared radiation heating显示文摘Hot air(HA)drying of banana has low drying efficiency and results in undesirable product quality.The objectives of this research were to investigate the feasibility of infrared(IR)heating to improve banana drying rate,evaluate quality of the dried product,and establish models for predicting drying characteristics.Banana slices of 5 mm and 8 mm thickness were dried with IR and HA at product temperatures of 60℃,70℃ and 80℃.Banana drying characteristics and changes in residual polyphenol oxidase(PPO),Hydroxymethylfurfural(HMF),color,moisture content(MC)and water activity during the treatments were investigated.Results showed that significant moisture reduction and higher drying rates were achieved with IR drying compared to HA drying in the early stage.The drying data could be fitted to the Page model for accurate prediction of MC change for IR and HA drying with mean R2 of 0.983.It was noted that enzyme inactivation occurred more quickly with IR than with HA drying.A unique response of PPO under IR and HA drying was revealed.IR heating of banana inactivated PPO within the first 20 min of drying at 60℃,70℃ and 80℃,while PPO was first activated before inactivation at 60℃ and 70℃ drying with HA.The highest HMF content occurred in banana slices with 5 mm thickness dried with IR at a product temperature of 80℃.It is therefore recommendable to dry banana with IR at product temperature of 70℃ or below to preserve the product quality.These findings are new and provide more insight in the application of IR heating for drying banana for improved drying rate and product quality. | Milly A.Pekke Zhongli Pan Griffiths G.Atungulu Gary Smith James F.Thompson | 2013 | International Journal of Agricultural and Biological Engineering2013，6，3： | 11 |
| 2 | Evaluation of Glycosaminoglycan in the Lumbar Disc Using Chemical Exchange Saturation Transfer MR at 3.0 Tesla:Reproducibility and Correlation with Disc Degeneration显示文摘Objective This study aims to explore the clinical applicability and relevance of glycosaminoglycan Chemical Exchange Saturation Transfer(gag CEST) for intervertebral disc. Methods 25 subjects ranging in age from 24 yrs to 74 yrs were enrolled. gag CEST was acquired using a single-slice TSE sequence on a 3T. Saturation used a continuous rectangular RF pulse with B1=0.8 μT and a fixed duration time =1100 ms. Sagittal image was obtained firstly without saturation pulse, and then saturated images were acquired at 52 offsets ranging from ±0.125 to ±7 parts per million(ppm). MR T2 relaxivity map was acquired at the identical location. Six subjects were scanned twice to assess scan-rescan reproducibility. Results Gag CEST intraclass correlation coefficient(ICC) of six subjects was 0.759 for nucleus pulposus(NP) and 0.508 for annulus fibrosus(AF). Bland-Altman plots showed NP had a mean difference of 0.10%(95% limits of agreement:-3.02% to 3.22%); while that of AF was 0.34%(95% limits of agreement:-2.28% to 2.95%). For the 25 subjects, gag CEST in NP decreased as disc degeneration increased, with a similar trend to T2 relaxivity. Gag CEST of AF showed a better correlation with disc degeneration than T2 relaxivity. Conclusion Gag CEST in NP and AF decreased as disc degeneration increased, while gag CEST in AF showed a better correlation than T2 relaxivity. | Deng Min Yuan Jing Chen Wei Tian Queenie Chan James F Griffith Wang Yi Xiang | 2016 | Biomedical and Environmental Sciences2016，29，1： | 8 |
| 3 | Imaging of the anterior cruciate ligament显示文摘The anterior cruciate ligament(ACL)is an important structure in maintaining the normal biomechanics of the knee and is the most commonly injured knee ligament.However,the oblique course of the ACL within the intercondylar fossa limits the visualization and assessment of the pathology of the ligament.This pictorial essay provides a comprehensive and illustrative review of the anatomy and biomechanics as well as updated information on different modalities of radiological investigation of ACL,particularly magnetic resonance imaging. | Wing Hung Alex Ng James Francis Griffith Esther Hiu Yee Hung Bhawan Paunipagar Billy Kan Yip Law Patrick Shu Hang Yung | 2011 | World Journal of Orthopedics2011，2，8： | 4 |
| 4 | Structural, densitometric and biomechanical evaluations of Chinese patients with long-term bisphosphonate treatment显示文摘 | LEUNG Kwok-sui TANG Ning James Griffith CHOY Tak-Kee HUNG Vivian Wing-Yin MOK Hoi-Wa SHI Lin LEUNG Ping-Chung CHEUNG Wing-Hoi | 2013 | Chinese Medical Journal2013，，1： | 4 |
| 5 | Acute myeloid leukemia is characterized by Wnt pathway inhibitor promoter hypermethylation显示文摘 | Elizabeth A. Griffiths Steven D. Gore Craig Hooker Michael A. McDevitt Judith E. Karp B. Douglas Smith Helai P. Mohammad Ying Ye James G. Herman Hetty E. Carraway | 2010 | Leukemia & Lymphoma2010，，9： | 3 |
| 6 | Induction and Maintenance Therapy With Infliximab for Children With Moderate to Severe Ulcerative Colitis显示文摘 | Jeffrey Hyams Lakshmi Damaraju Marion Blank Jewel Johanns Cynthia Guzzo Harland S. Winter Subra Kugathasan Stanley Cohen James Markowitz Johanna C. Escher Gigi Veereman–Wauters Wallace Crandall Robert Baldassano Anne Griffiths | 2012 | Clinical Gastroenterology and Hepatology2012，，4： | 3 |
| 7 | Characteristics of Rat Lumbar Vertebral Body Bone Mineral Density and Differential Segmental Responses to Sex Hormone Deficiency:a Clinical Multidetector Computed Tomography Study显示文摘Objective To investigate sex hormone deficiency related osteoporosis and efficacy of different therapies. Methods Orchiectomized and ovariectomized rat models are used to investigate sex hormone deficiency related osteoporosis and efficacy of different therapies. A rat vertebral body can be longitudinally divided into central portion, which contain more trabecular bone, and para-endplate portions which contain more compact bone. In matured male and female Wistar and Sprague-Dawley rat lumbar spines, we investigated baseline bone mineral density (BMD) characteristics and the differential segmental responses in bone loss within the lumbar vertebral body post gonadal surgery with clinical multidetector computed tomography. Results Para-endplate sections had a higher BMD than central sections. The cephalad para-endplate sections had a higher BMD than the caudad para-endplate sections. Eight weeks after gonadal removal, there was more bone loss in central sections than para-endplate sections. The relative difference of bone loss between para-endplate and central sections was more apparent in male rats than in female rats. There was more bone loss in caudad sections than cephalad sections; this lead to a further increase of BMD difference between caudad para-endplate sections and cephalad para-endplate sections post gonadal surgery. Conclusion The approach described in this study provided a consistent way to study BMD change within predominantly compact bone portion and trabecular bone portion of the vertebral body. | DENG Min WANG Yi Xiang James F. GRIFFITH LU Gang Anil T AHUJA POON Wai S | 2012 | Biomedical and Environmental Sciences2012，25，6： | 2 |
| 8 | Modelling the impact of sea-level rise on urban flood probability in SE China显示文摘Urban drainage systems in coastal cities in SE China are characterized by often complex canal and sluicegate systems that are designed to safely drain pluvial flooding whilst preventing tidal inundation.However, the risk of coastal flooding in the region is expected to increase over the next 50-100 years, as urban areas continue to expand and sea-levels are expected to rise. To assess the impact of projected sealevel rise on this type of urban drainage system, a one-dimensional model and decision support tool was developed. The model indicated that although sea-level rise represents a significant challenge, flood probability will continue to be most influenced by rainfall. Events that are significant enough to cause flooding will most likely be minimally impacted by changes to the tidal frame. However, it was found that a sea-level rise of up to 1.2 m by 2010 would result in increased drainage times and higher volumes of over-topping when flooding occurs. | James Andrew Griffiths Fangfang Zhu Faith Ka Shun Chan David Laurence Higgitt | 2019 | Geoscience Frontiers2019，10，2： | 2 |
| 9 | Hepatitis C virus NS3 RNA helicase domain with a bound oligonucleotide: the crystal structure provides insights into the mode of unwinding显示文摘 | Joseph L Kim Kurt A Morgenstern James P Griffith Maureen D Dwyer John A Thomson Mark A Murcko Chao Lin Paul R Caron | 1998 | Structure1998，，1： | 1 |
| 10 | Vascular calcification does not predict anastomotic leak or conduit necrosis following oesophagectomy显示文摘BACKGROUND Anastomotic leaks(AL)and gastric conduit necrosis(CN)are serious complications following oesophagectomy.Some studies have suggested that vascular calcification may be associated with an increased AL rate,but this has not been validated in a United Kingdom population.AIM To investigate whether vascular calcification identified on the pre-operative computed tomography(CT)scan is predictive of AL or CN.METHODS Routine pre-operative CT scans of 414 patients who underwent oesophagectomy for malignancy with oesophagogastric anastomosis at the Queen Elizabeth Hospital Birmingham between 2006 and 2018 were retrospectively analysed.Calcification of the proximal aorta,distal aorta,coeliac trunk and branches of the coeliac trunk was scored by two reviewers.The relationship between these calcification scores and occurrence of AL and CN was then analysed.The Esophagectomy Complications Consensus Group definition of AL and CN was used.RESULTS Complication data were available in n=411 patients,of whom 16.7%developed either AL(15.8%)or CN(3.4%).Rates of AL were significantly higher in female patients,at 23.0%,compared to 13.9%in males(P=0.047).CN was significantly more common in females,(8.0%vs 2.2%,P=0.014),patients with diabetes(10.6%vs 2.5%,P=0.014),a history of smoking(10.3%vs 2.3%,P=0.008),and a higher American Society of Anaesthesiologists grade(P=0.024).Out of the 14 conduit necroses,only 4 occurred without a concomitant AL.No statistically significant association was found between calcification of any of the vessels studied and either of these outcomes.Multivariable analyses were then performed to identify whether a combination of the calcification scores could be identified that would be significantly predictive of any of the outcomes.However,the stepwise approach did not select any factors for inclusion in the final models.The analysis was repeated for composite outcomes of those patients with either AL or CN(n=69,16.7%)and for those with both AL and CN(n=10,2.4%)and again,no significant associations were detected.In the subset of patients that developed these outcomes,no significant associations were detected between calcification and the severity of the complication.CONCLUSION Calcification scoring was not significantly associated with Anastomotic Leak or CN in our study,therefore should not be used to identify patients who are high risk for these complications. | Benjamin J Jefferies Emily Evans James Bundred James Hodson John L Whiting Colm Forde Ewen A Griffiths | 2019 | World Journal of Gastrointestinal Surgery2019，11，7： | 1 |
| 11 | Transversus abdominis plane block does not provide additional benefit to muhimodal analgesia in gyneco- logical cancer surgery显示文摘 | James D Griffiths MB | 2010 | Anesth Analg2010，111，： | 1 |
| 12 | Transversus Abdominis Plane Block Does Not Provide Additional Benefit to Multimodal Analgesia in Gynecological Cancer Surgery显示文摘 | James D. Griffiths Justine V. Middle Fiona A. Barron Sarah J. Grant Phillip A. Popham Colin F. Royse | 2010 | Anesthesia & Analgesia2010，，3： | 1 |
| 13 | Extraintestinal Manifestations of Pediatric Inflammatory Bowel Disease and Their Relation to Disease Type and Severity显示文摘 | Jennifer L Dotson Jeffrey S Hyams James Markowitz Neal S LeLeiko David R Mack Jonathan S Evans Marian D Pfefferkorn Anne M Griffiths Anthony R Otley Athos Bousvaros Subra Kugathasan Joel R Rosh David Keljo Ryan S Carvalho Gitit Tomer Petar Mamula Marsha H | 2010 | Journal of Pediatric Gastroenterology and Nutrition2010，，2： | 1 |
| 14 | The Development and Validation of the Statistics Comprehensive Anxiety Response Evaluation 显示文摘 | JAMES GRIFFITH ANDILE M1J MOKHTAR WEISANI | 2014 | International Journal of Ad- vances in Psychology2014，3，2： | 1 |
| 15 | Growth Abnormalities Persist in Newly Diagnosed Children With Crohn Disease Despite Current Treatment Paradigms显示文摘 | Marian Pfefferkorn Georgine Burke Anne Griffiths James Markowitz Joel Rosh David Mack Anthony Otley Subra Kugathasan Jonathan Evans Athos Bousvaros M Susan Moyer Robert Wyllie Maria Oliva-Hemker Ryan Carvalho Wallace Crandall David Keljo TD Walters Neal L | 2009 | Journal of Pediatric Gastroenterology and Nutrition2009，，2： | 1 |
| 16 | Undersized Tricuspid Annuloplasty Rings Optimally Treat Functional Tricuspid Regurgitation显示文摘 | Mehrdad Ghoreishi Jamie M. Brown Craig E. Stauffer Cindi A. Young Mary J. Byron Bartley P. Griffith James S. Gammie | 2011 | The Annals of Thoracic Surgery2011，，1： | 1 |
| 17 | A Pseudo-Response Regulator is misexpressed in the photoperiod insensitive Ppd-D1a mutant of wheat (Triticum aestivum L.)显示文摘 | James Beales Adrian Turner Simon Griffiths John W. Snape David A. Laurie | 2007 | Theoretical and Applied Genetics2007，，5： | 1 |
| 18 | Curcumin abrogates bile-induced NF-κB activity and DNA damage in vitro and suppresses NF-κB activity whilst promoting apoptosis in vivo, suggesting chemopreventative potential in Barrett’s oesophagus显示文摘 | Nihit Rawat Ali Alhamdani Elizabeth McAdam James Cronin Zak Eltahir Paul Lewis Paul Griffiths John N. Baxter Gareth J. S. Jenkins | 2012 | Clinical and Translational Oncology2012，，4： | 1 |
| 19 | The first commercial supercritical water oxidation sludge processing plant显示文摘 | James W Griffith Dennis H Raymond | 2002 | Waste Manage2002，22，4： | 1 |
| 20 | Overgeneral autobiographical memory as a predictor of the course of depression: A meta-analysis显示文摘 | Jennifer A. Sumner James W. Griffith Susan Mineka | 2010 | Behaviour Research and Therapy2010，，7： | 1 |
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