|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Identification and characterization of mRNA transcripts differentially expressed in response to high salinity by means of differential display in the mangrove,Bruguiera gymnorrhiza显示文摘 | Banzai T Gitit Hershkovits Katcoff D J | 2002 | Plant Science2002，162，4： | 2 |
| 2 | Extraintestinal Manifestations of Pediatric Inflammatory Bowel Disease and Their Relation to Disease Type and Severity显示文摘 | Jennifer L Dotson Jeffrey S Hyams James Markowitz Neal S LeLeiko David R Mack Jonathan S Evans Marian D Pfefferkorn Anne M Griffiths Anthony R Otley Athos Bousvaros Subra Kugathasan Joel R Rosh David Keljo Ryan S Carvalho Gitit Tomer Petar Mamula Marsha H | 2010 | Journal of Pediatric Gastroenterology and Nutrition2010，，2： | 1 |
| 3 | Improved Outcomes With Quality Improvement Interventions in Pediatric Inflammatory Bowel Disease显示文摘 | Charles M. Samson Pamela Morgan Elizabeth Williams Lee Beck RicJunette Addie-Carson Stacy McIntire Andrea Booth Eduardo Mendez Carolyn Luzader Gitit Tomer Shehzad Saeed Edward Donovan John Bucuvalas Lee A. Denson | 2012 | Journal of Pediatric Gastroenterology and Nutrition2012，，6： | 1 |
| 4 | Language breakdown and linguistic theory: a tutorial overview显示文摘 | Yonata Levy Gitit Kave | 1999 | Lingua (S0024-- 3841)1999，，： | 1 |
| 5 | Isao KIdentification and characterization of mRNA transcripts differentially expressed in response to high salinity by means of differential display in the mangrove, Bruguiera gymnorrhiza 显示文摘 | BANZAIA T GITIT H DON J | 2002 | Plant Science2002，4，162： | 1 |
| 6 | Obtaining research biopsies during pediatric colonoscopy: Safety and adverse events显示文摘AIM: To investigate the safety profile of acquiring additional intestinal biopsies for research purposes in children undergoing a medically indicated colonoscopy. METHODS: A retrospective review of 122 pediatric patients who underwent colonoscopy over a 9 mo time period was completed. 38/122 participants consented to a research study in which 4 additional biopsies were obtained, in addition to routine biopsies. The outcomes after colonoscopy were measured in the research participants, and compared to 84 control participants who did not consent for the study. Groups were compared with regard to number of biopsies obtained, underlying diagnosis, and both serious and minor adverse outcomes. Data was collected including: age, gender, race, indication, diagnosis, number of biopsies obtained per case and post procedure adverse events. Medical records were reviewed and a questionnaire was completed by each of the ten gastroenterologists who performed procedures during the study. Physicians were asked about individual patient outcomes to ensure that all adverse events, such as perforation, excessive bleeding, infection, and minor gastrointestinal outcomes, were captured and included.RESULTS: The research group had more biopsies obtained(mean = 13.58 ± 4.21) compared to controls(mean = 9.33 ± 4.40), P ≤ 0.0001, however there was no difference in adverse events. Serious outcomes, defined as perforation, bleeding and infection, did not occur, in either group. As such, the relationship between serious adverse events and number of biopsies obtained was not determined. Minor gastrointestinal outcomes, such as abdominal pain, diarrhea or vomiting, were reported in 21 patients(8 research participants and 13 control participants) however the incidence of minor gastrointestinal outcomes between the two groups did not vary significantly, P = 0.45. Additionally, the meannumber of biopsies obtained in patients who had a minor outcome(mean = 12.1 ± 0.77), compared to those with no adverse outcome(mean = 10.34 ± 0.5), revealed no statistical difference between the groups(P = 0.12), suggesting that number of biopsies is not associated with incidence of minor adverse events.CONCLUSION: Patients participating in research requiring acquisition of additional biopsies for research purposes alone, are not at an increased risk of adverse outcomes. | Jennifer Mait-Kaufman Stacie Kahn Gitit Tomer | 2015 | World Journal of Gastrointestinal Endoscopy2015，7，7： | 1 |
| 7 | Improved Outcomes With Quality Improvement Interventions in Pediatric Inflammatory Bowel Disease显示文摘 | Charles M. Samson Pamela Morgan Elizabeth Williams Lee Beck RicJunette Addie-Carson Stacy McIntire Andrea Booth Eduardo Mendez Carolyn Luzader Gitit Tomer Shehzad Saeed Edward Donovan John Bucuvalas Lee A. Denson | 2012 | Journal of Pediatric Gastroenterology and Nutrition2012，，6： | 1 |
| 8 | Effects of omega-3 supplementation on components of the endocannabinoid system and metabolic and inflammatory responses in adipose and liver of peripartum dairy cows显示文摘Background:Dietary supplementation of omega-3 fatty acids can reduce the activation of the endocannabinoid system(ECS)by decreasing the availability of arachidonic acid,thus lowering endocannabinoids(e CBs)levels.The ECS is a modulator of energy metabolism,stress response and inflammation in mammals,yet there is little information on the roles of the ECS in transition dairy cows.During the periparturient period,the adipose tissue and liver are the main metabolic organs that participate in the adaptations of dairy cows to onset of lactation;however,exceeded adipose tissue lipolysis and accumulation of lipids in the liver have adverse effects on cows'physiology.Here we aimed to examine whether omega-3 supplementation during the transition period will modulate ECS activation and affect metabolic and inflammatory indices in postpartum dairy cows,by supplementing twenty-eight transition Holstein dairy cows with either saturated fat(CTL)or encapsulated flaxseed oil(FLX).Components of the ECS,metabolic and inflammatory markers were measured in blood,liver,and subcutaneous adipose tissue.Results:FLX supplementation reduced feed intake by 8.1%(P<0.01)and reduced plasma levels of arachidonic acid(by 44.2%;P=0.02)and anandamide(by 49.7%;P=0.03)postpartum compared to CTL.The m RNA transcription levels of the cannabinoid receptor 1(CNR1/CB1)tended to be lower(2.5 folds)in white blood cells of FLX than in CTL(P=0.10),and protein abundance of ECS enzyme monoacylglycerol lipase was higher in peripheral blood mononuclear cells of FLX than in CTL(P=0.04).In adipose tissue,palmitoylethanolamide levels were lower in FLX than in CTL(by 61.5%;P=0.02),relative m RNA transcription of lipogenic genes were higher,and the protein abundance of cannabinoid receptor 2(P=0.08)and monoacylglycerol lipase(P=0.10)tended to be higher in FLX compared to CTL.Hepatic 2-arachidonoylglycerol tended to be higher(by 73.1%;P=0.07),and interlukin-6 m RNA transcription level was 1.5 folds lower in liver of FLX than in CTL(P=0.03).Conclusions:Nutritional supplementation of omega-3 fatty acids seems to partly modulate ECS activation,which could be related to lower feed intake.The altered ECS components in blood,adipose tissue and liver are associated with moderate modulations in lipid metabolism in the adipose and inflammation in liver of peripartum dairy cows. | Gitit Kra Jayasimha Rayalu Daddam Uzi Moallem Hadar Kamer Radka Kočvarova Alina Nemirovski GAndres Contreras Joseph Tam Maya Zachut | 2023 | Journal of Animal Science and Biotechnology2023，14，1： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员