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| 1 | Modulation of the MAP kinase signaling cascade by Raf kinase inhibitory protein显示文摘Proteins like Raf kinase inhibitory protein (RKIP) that serve as modulators of signaling pathways, either by promoting or inhibiting the formation of productive signaling complexes through protein-protein interactions, have been demon- strated to play an increasingly important role in a number of cell types and organisms. These proteins have been implicated in development as well as the progression of cancer. RKIP is a particularly interesting regulator, as it is a highly conserved, ubiquitously expressed protein that has been shown to play a role in growth and differentiation in a number of organisms and can regulate multiple signaling pathways. RKIP is also the first MAP kinase signaling modulator to be identified as playing a role in cancer metastasis, and identification of the mechanism by which it regulates Raf-1 activation provides new targets for therapeutic intervention. | Nicholas TRAKUL Marsha R. ROSNER | 2005 | Cell Research2005，15，1： | 25 |
| 2 | 渠道权力理论与国外品牌服装在我国的营销渠道显示文摘本文利用渠道权力理论研究了国外品牌服装在我国营销渠道中零售商和供应商的关系。运用结构方程模型分析了供应商拥有的权力、零售商所感受到的供应商的影响力、二者在合作中的冲突、零售商对供应商的态度以及满意程度这几个因素之间的关系。结果表明,供应商拥有的法律权力是影响零售商的主要原因;供应商具有的专家权力和相关权力正面影响零售商对自己的态度;零售商感觉来自供应商的权力越大,则其与供应商发生冲突的可能性越大;零售商对供应商的态度会影响供应商对其的满意程度,消极的态度会引发冲突。另外,本文发现渠道成员对权力的感受以及其产生的影响与渠道所处的人文、社会和商业背景密切相关。 | 张黎 Marsha A.Dickson | 2004 | 南开管理评论2004，7，4： | 20 |
| 3 | 学龄前儿童体力活动研究的10大问题显示文摘本文目的是回顾与3~5岁儿童体力活动有关的重要研究问题。本文将从三个主要研究领域进行分析:健康效果、体力活动模式、干预和政策。研究的主要问题包括:确定体力活动的健康效果,确定体力活动对保持健康体重的影响,探明体力活动对学习和行为习惯的影响,以及静坐行为对健康的影响。与体力活动模式相关的研究问题包括3~5岁儿童满足现有体力活动推荐量的情况;影响体力活动的社会和环境因素,包括家庭、幼儿园、社区环境;体力活动如何对学龄儿童期、青少年时期和成年以后产生影响。关于干预和政策方面的研究问题包括确定在家庭、保育机构、社区环境最有效的促进体力活动的干预策略,以及不同幼儿适用的干预方案;确定有效的干预手段和宣传策略;制定有效的能够增加幼儿体力活动水平的国家、州、地方和机构的政策。总之,全面了解体力活动对3~5岁儿童健康的影响,以便于掌握该群体的体力活动特点,探索如何促进幼儿的体力活动。 | Russell R.Pate Jennifer R.O'Neill William H.Brown Kerry L.McIver Erin K.Howie Marsha Dowda | 2015 | 北京体育大学学报2015，38，6： | 19 |
| 4 | Raf kinase inhibitory protein: a signal transduction modulator and metastasis suppressor显示文摘房间有大量的控制维持他们的完整并且阻止随机切换到另外一个一个生物状态。Raf Kinase 禁止的蛋白质(RKIP ) , phosphatidylethanolamine 绑定蛋白质(PEBP ) 的一个成员家庭,表明工作维持“ yin yang ”或生物系统的平衡的串联的调节的人的一个新类是代表性的。RKIP 禁止地图 kinase (Raf-MEK-ERK ) ,表明串联的 G 联合蛋白质的受体(GPCR ) kinase 和 NFkappaB。因为 RKIP 指向依赖于它磷酸化的状态的不同家族 ases, RKIP 也行动集成多重环境刺激开始的串音。RKIP 的损失或弄空导致正常细胞的壅滞和罐头的混乱导致象癌症那样的 chromosomal 畸形和疾病状态。因为 RKIP 和 PEBP 家庭以前被考察了,这分析的目标是提供更改并且加亮一些 RKIP 的唯一的特征在细胞的发信号的过程的规定使它成为一个批评播放器。 | Alexey E Granovsky Marsha Rich Rosner | 2008 | Cell Research2008，18，4： | 9 |
| 5 | 加拿大基层医疗改革的创新型及多元化策略显示文摘基层医疗卫生服务体系在世界各国的医疗卫生服务系统中均发挥着重要作用。在过去十年中,加拿大省及地方卫生系统运用了多种方法改善基层医疗卫生服务,改革方案涵盖了目标医疗组织架构、医疗服务者薪酬、医疗服务者数量、医疗服务质量及安全性等方面,改革成果大大提升了家庭医学这个专业实践领域的吸引力,家庭医学吸引了越来越多的医学应届毕业生。这对我国健全基层医疗卫生服务体系具有重要借鉴意义。为此,本刊特别翻译和报道了加拿大基层医疗改革的创新型及多元化策略,敬请关注! | Erin Strumpf Jean-Frédéric Levesque Natalie Coyle Brian Hutchison Marsha Barnes Robert J.Wedel 魏亚萌 | 2015 | 中国全科医学2015，18，31： | 4 |
| 6 | Johanson-Blizzard syndrome with mild phenotypic features confirmed by UBR1 gene testing显示文摘Johanson-Blizzard syndrome (JBS) is a rare autosomal recessive condition associated with exocrine pancreatic insufficiency,and is characterized by hypoplastic nasal alae,mental retardation,sensorineural hearing loss,short stature,scalp defects,dental abnormalities and abnormal hair patterns. Growth hormone deficiency,hypopituitarism,and impaired glucagon secretion response to insulin-induced hypoglycemia have been reported. Congenital heart defects have also been described in this condition. Mental retardation is typically moderate to severe in patients with JBS; however,normal intelligence can occur. In the pancreas,there is a selective defect of acinar tissue,whereas the islets of Langerhans and ducts are preserved. Diabetes has been reported in older children,suggesting the progressive nature of pancreatic disease. The molecular basis of JBS has recently been mapped to chromosome 15q15-q21 with identified mutations in the UBR1 gene. We report the case of a 7-year-old female with pancreatic insufficiency and mild phenotypic features,in whom the diagnosis of JBS was established using recently described molecular testing for the UBR1 gene. | Naim Alkhouri Barbara Kaplan Marsha Kay Amy Shealy Carol Crowe Susanne Bauhuber Martin Zenker | 2008 | World Journal of Gastroenterology2008，14，44： | 4 |
| 7 | Pro-apoptotic and anti-proliferative effects of Physalis angulata leaf extract on retinoblastoma cells显示文摘AIM: To investigate the effect of Physalis angulata leaf extract on apoptotic and proliferation of retinoblastoma cells. Despite several previous studies evidencing the anticancer potential of Physalis angulata;however, certain study that proves its benefits in retinoblastoma cancer cells has been limited.METHODS: This study utilizes an in-vitro experimental study by applying Y79 human retinoblastoma cell line culture obtained from the American Type Culture Collection(ATCC;10801 University Boulevard Manassas, VA 20110, USA). The cell was divided into 4 groups. Group I was the control group without the administration of Physalis angulata leaf extract. Whereas, group II, II and IV are engaged with 25, 50, and 100 μg/mL of Physalis angulata leaf extract respectively. After a 24 h incubation, an examination with microtetrazolium(MTT) cell proliferation assay and Annexin V apoptosis detection was conducted. Statistical analysis was performed with the Tukey test.RESULTS: Physalis angulata leaf extract improved apoptosis and significantly reduced the number of living cells in retinoblastoma cells, along with the increase in the given dose. Based on the Tukey test, a significant difference was found in the treatment group at 50 μg/mL(P=0.025) and 100 μg/mL(P=0.001) in the measurement of apoptosis. Proliferation measurements also indicated a significant decrease in the number of living cells in the 50μg/m L treatment group(P=0.004), and in the 100 μg/mL treatment group(P=0.000). Meanwhile, a dose of 25 μg/mL indicated insignificant difference in the two measurements. Improved apoptosis and decreased number of living cells occured at a dose of 100 μg/mL. Decreased number of living cells(in the measurement of proliferation) was due to the inhibited proliferation or improved apoptosis.CONCLUSION: Physalis angulata leaf extract improve apoptosis in retinoblastoma cell culture, requiring further research to inhibit proliferation. | Marsha Dechastra Chairissy Lely Retno Wulandari Hidayat Sujuti | 2019 | International Journal of Ophthalmology(English edition)2019，12，9： | 3 |
| 8 | Consensus Statement of the Academy of Nutrition and Dietetics/American Society for Parenteral and Enteral Nutrition: Characteristics Recommended for the Identification and Documentation of Adult Malnutrition (Undernutrition)显示文摘 | Jane V. White Peggi Guenter Gordon Jensen Ainsley Malone Marsha Schofield | 2012 | Journal of the Academy of Nutrition and Dietetics2012，，5： | 2 |
| 9 | 美国创建和利用民间生活收藏的新方向显示文摘民间生活研究在美国的发展已有数百年的悠久历史,即使没有数以千计,也有数以百计的收藏。计算机技术也正在深层次上改变着民间生活收藏的发展、维护、获取和运用。以密西根州立大学博物馆为主体的三个研究和记录项目正富有创造力地运用技术来生成和保存传统文化的收藏,它们分别是被套索引、密西根彩绘玻璃普查与密西根谷仓与农庄调查。同时,这些项目正以新的方式运用技术来吸引和支持教育和学术上对这些收藏的使用。这三个项目证明识别和稳定世界民间生活收藏的基本重要性,而且让人们可以获得并一般性地搜索世界的民间生活藏品。 | marsha macdowell 陈熙 | 2011 | 文化遗产2011，，1： | 2 |
| 10 | The generation of endostatin is mediated by elastase显示文摘 | Wen W Marsha A Dmitr M | | 0，，： | 2 |
| 11 | Mesuring Emotion in the Eonsumption Experience显示文摘 | Marsha l | 1997 | Juornal of Jonsumer Research1997，24，2： | 1 |
| 12 | Some Theoretical and Popular Notions Concerning Materialism 显示文摘 | Foumier Susan Richins Marsha L | 1991 | Journal of Social Behavior and Personality1991，6，： | 1 |
| 13 | Effect of pulse rate on collagen deposition in the tissue-engineered blood vessel显示文摘 | Amy S Shannon M Marsha M | 2004 | Tissue Eng2004，9，： | 1 |
| 14 | The Peripherally Inserted Central Catheter:What Are the Current Indications for Its Use显示文摘 | Marsha E Creativ E | 2012 | Arizona Nutrition in Clinical Practice2012，17，2： | 1 |
| 15 | Is Spine Deformity Surgery in Patients With Spastic Cerebral Palsy Truly Beneficial?: A Patient/Parent Evaluation显示文摘 | Kota Watanabe Lawrence G. Lenke Michael D. Daubs Kei Watanabe Keith H. Bridwell Georgia Stobbs Marsha Hensley | 2009 | Spine2009，，20： | 1 |
| 16 | Rapid and accurate determination of the potency of varicella vaccine by quantitive polymerase chain reaction 显示文摘 | Marsha S Russell Changgui Li Louise Larocque | 2011 | Vaccine2011，29，： | 1 |
| 17 | Word of Mouth communication in market 显示文摘 | Marsha K | 2010 | Advances in Consumer Research2010，，1： | 1 |
| 18 | Preferences for self-management support: Findings from a survey of diabetes patients in safety-net health systems显示文摘 | Urmimala Sarkar John D. Piette Ralph Gonzales Daniel Lessler Lisa D. Chew Brendan Reilly Jolene Johnson Melanie Brunt Jennifer Huang Marsha Regenstein Dean Schillinger | 2007 | Patient Education and Counseling2007，，1： | 1 |
| 19 | Efficacy of perioperative halo-gravity traction for treatment of severe scoliosis (≥100°)显示文摘 | Kei Watanabe Lawrence G. Lenke Keith H. Bridwell Yongjung J. Kim Marsha Hensley Linda Koester | 2010 | Journal of Orthopaedic Science2010，，6： | 1 |
| 20 | Special Possessions and the Expression of Material Values显示文摘 | Richins Marsha | 1994 | Journal of Consumer Reseach1994，21，： | 1 |
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