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| 1 | Experimental small bowel preservation using Polysol: A new alternative to University of Wisconsin solution, Celsior and histidine-tryptophan-ketoglutarate solution?显示文摘AIM: To evaluate the potential of Polysol, a newly developed preservation solution, in cold storage of small bowel grafts, compared with the current standards, University of Wisconsin solution (UW), Celsior and histidine-tryptophan-ketoglutarate solution (HTK). METHODS: Male Wistar rats were used as donors. Small bowels were retrieved, flushed and then stored in the respective 4 solutions for 18 h at 4℃. Functional integrity of the grafts was evaluated by isolated reperfusion with oxygenated Krebs-Henseleit buffer at 37℃ for 30 min in all 4 groups. RESULTS: Polysol preservation exhibited the highest tissue ATP concentration and the lowest release of LDH. Malondialdehyde, an index for tissue lipid peroxidation, was also the lowest in Polysol. Tissue oxygen consumption was significantly higher in Polysol than in the others. Of interest, UW-storage promoted 10-fold higher apoptosis than in the others. Moreover, electron microscopy revealed that the mucosal villi/micro-villi formation and the cell organelles, including mitochondria, were both significantly better preserved in Polysol, while deleterious alterations were apparent in the others, most notably in UW. Although Celsior and HTK exhibited the better trend of results than UW in some parameters, but could not reach the over-all superiority to UW.CONCLUSION: Cold storage using Polysol resulted in significantly better integrity and function of small bowel grafts than UW. Hence, Polysol may be a novel alternative for the small bowel preservation. | Lai Wei Koichiro Hata Benedict Marie Doorschodt Reinhard Büttner Thomas Minor René H Tolba | 2007 | World Journal of Gastroenterology2007，13，27： | 9 |
| 2 | m^6A-epitranscriptome modulates memory strength显示文摘Memory traces are modified during several hours following learning, to produce behaviorally adaptive long-term memories. In a recent paper published in Cell Research, Zhang et al. provide evidence that N 6 -methyladenosine modification of mRNAs augments the strength of weak memories. | Sebastian Krüttner Pico Caroni | 2019 | Cell Research2019，29，1： | 3 |
| 3 | First performance evaluation of a dual-source CT (DSCT) system显示文摘 | Thomas G. Flohr Cynthia H. McCollough Herbert Bruder Martin Petersilka Klaus Gruber Christoph Sü? Michael Grasruck Karl Stierstorfer Bernhard Krauss Rainer Raupach Andrew N. Primak Axel Küttner Stefan Achenbach Christoph Becker Andreas Kopp Bernd M. Ohnes | 2006 | European Radiology2006，，6： | 3 |
| 4 | Ultrasound Doppler system for two-dimensional flow mapping in liquid metals显示文摘 | Sven Franke Lars Büttner Jürgen Czarske Dirk R?biger Sven Eckert | 2010 | Flow Measurement and Instrumentation2010，，3： | 3 |
| 5 | Analysis of genomic rearrangement and subsequent gene deletion of the attenuated Orf virus strain D1701显示文摘 | Rosita Cottone Mathias Büttner Berthilde Bauer Marco Henkel Eduard Hettich Hanns-Joachim Rziha | 1998 | Virus Research1998，，1： | 3 |
| 6 | Taking out the garbage:cathepsin D and calcineurin in neurodegeneration显示文摘Cellular homeostasis requires a tightly controlled balance between protein synthesis, folding and degradation. Especially long-lived, post-mitotic cells such as neurons depend on an efficient proteostasis system to maintain cellular health over decades. Thus, a functional decline of processes contributing to protein degradation such as autophagy and general lysosomal proteolytic capacity is connected to several age-associated neurodegenerative disorders, including Parkinson's, Alzheimer's and Huntington's diseases. These so called proteinopathies are characterized by the accumulation and misfolding of distinct proteins, subsequently driving cellular demise. We recently linked efficient lysosomal protein breakdown via the protease cathepsin D to the Ca^(2+)/calmodulin-dependent phosphatase calcineurin. In a yeast model for Parkinson's disease, functional calcineurin was required for proper trafficking of cathepsin D to the lysosome and for recycling of its endosomal sorting receptor to allow further rounds of shuttling. Here, we discuss these findings in relation to present knowledge about the involvement of cathepsin D in proteinopathies in general and a possible connection between this protease, calcineurin signalling and endosomal sorting in particular. As dysregulation of Ca^(2+) homeostasis as well as lysosomal impairment is connected to a plethora of neurodegenerative disorders, this novel interplay might very well impact pathologies beyond Parkinson's disease. | Andreas Aufschnaiter Verena Kohler Sabrina Büttner | 2017 | Neural Regeneration Research2017，12，11： | 3 |
| 7 | A Novel Line Immunoassay Based on Recombinant Virulence Factors Enables Highly Specific and Sensitive Serologic Diagnosis of Helicobacter pylori Infection显示文摘 | Luca Formichella Laura Romberg Christian Bolz Michael Vieth Michael Geppert Gereon G?ttner Christina N?lting Dirk Walter Wolfgang Schepp Arne Schneider Kurt Ulm Petra Wolf Dirk H. Busch Erwin Soutschek Markus Gerhard | 2013 | Clinical and Vaccine Immunology2013，，11： | 2 |
| 8 | Genetic characterization and phylogenetic position of Echinococcus felidis Ortlepp, 1937 (Cestoda: Taeniidae) from the African lion显示文摘 | Marion Hüttner Minoru Nakao Torsten Wassermann Ludwig Siefert Joop D.F. Boomker Anke Dinkel Yasuhito Sako Ute Mackenstedt Thomas Romig Akira Ito | 2007 | International Journal for Parasitology2007，，7： | 2 |
| 9 | Postoperative pain after transvaginal cholecystectomy: single-center, double-blind, randomized controlled trial显示文摘 | Dietmar H. Borchert Matthias Federlein Frauke Fritze-Büttner Jens Burghardt Britta Liersch-L?hn Yüksel Atas Verena Müller Oskar Rückbeil Stefan Wagenpfeil Stefan Gr?ber Klaus Gellert | 2014 | Surgical Endoscopy2014，，6： | 2 |
| 10 | Challenges of automated screening and differentiation of non-organ specific autoantibodies on HEp-2 cells显示文摘 | Hiemann R Büttner T Krieger T | 2009 | Autoimmun Rev2009，9，1： | 1 |
| 11 | Incommensurate ground states in a one-dimensional model for electron-libron coupling in polyaniline显示文摘 | Baranowski D Büttner H | 1995 | Phys Rev1995，51，： | 1 |
| 12 | Port of entry:the type Ⅲ secretion translocon 显示文摘 | Büttner D Bonas U | 2002 | Trends in Microbiology2002，10，4： | 1 |
| 13 | Off-flavours in water:Hydroxyketones and β-ionone derivatives as new odour compounds of freshwater cyanobacteria显示文摘 | H?ckelmann C Jüttner F | 2005 | Flavour and Fragrance Journal2005，20，4： | 1 |
| 14 | Gastrointestinale Stromatumoren des Magens显示文摘 | E. Wardelmann P. Hohenberger P. Reichardt S. Merkelbach-Bruse H.-U. Schildhaus R. Büttner | 2010 | Der Pathologe2010，，3： | 1 |
| 15 | The transcallosal interforniceal approach to the third ventricle:anatomic and microsurgical aspects显示文摘 | Winkler PA Weis S Büttner A | 1997 | Neurosurgery1997，40，5： | 1 |
| 16 | First performance evaluation of a dual-source CT (DSCT) system显示文摘 | Thomas G. Flohr Cynthia H. McCollough Herbert Bruder Martin Petersilka Klaus Gruber Christoph Süβ Michael Grasruck Karl Stierstorfer Bernhard Krauss Rainer Raupach Andrew N. Primak Axel Küttner Stefan Achenbach Christoph Becker Andreas Kopp Bernd M. Ohnes | 2006 | European Radiology2006，，2： | 1 |
| 17 | MDCT:cardiology indications显示文摘 | Kopp AF Küttner A Trabold T | | 0，，5： | 1 |
| 18 | Supply Chain Risk Management:Outlining an Agenda for Future Research显示文摘 | Jüttner U Peck H Christopher M | | 0，，： | 1 |
| 19 | PGE1 and PGE2 modify platelet function through different prostanoid receptors显示文摘 | Iyú D Jüttner M Glenn JR | 2011 | Prostaglandins Other Lipid Mediat2011，94，12： | 1 |
| 20 | Developing strategic partnerships in the supply chain: a practitioner perspective显示文摘 | Martin Christopher Uta Jüttner | 2000 | European Journal of Purchasing and Supply Management2000，，2： | 1 |
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