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| 1 | 超声对腕管综合征的评估:病人与健康志愿者正中神经横断面积测量的价值显示文摘目的 通过比较腕管水平及近端旋前方肌水平正中神经横断面积(CSA)以提高诊断腕管综合征(CTS)的准确性。方法 研究方案获机构审查委员会的批准,并得到所有被检查者的书面知情同意。68例连续的CTS病人的100个手腕(男16例,女52例;平均年龄57.9岁,范围25~85岁)和58名健康志愿者的93个手腕(男16例,女42例; | A.S.Klauser E.J.Halpern T.De Zordo G.M.Feuchtner R.Arora J. Gruber 陈聪 | 2009 | 国际医学放射学杂志2009，32，2： | 15 |
| 2 | Dental and periodontal phenotype in sclerostin knockout mice显示文摘Sclerostin is a Wnt signalling antagonist that controls bone metabolism.Sclerostin is expressed by osteocytes and cementocytes;however,its role in the formation of dental structures remains unclear.Here,we analysed the mandibles of sclerostin knockout mice to determine the influence of sclerostin on dental structures and dimensions using histomorphometry and micro-computed tomography(mCT)imaging.mCT and histomorphometric analyses were performed on the first lower molar and its surrounding structures in mice lacking a functional sclerostin gene and in wild-type controls.mCT on six animals in each group revealed that the dimension of the basal bone as well as the coronal and apical part of alveolar part increased in the sclerostin knockout mice.No significant differences were observed for the tooth and pulp chamber volume.Descriptive histomorphometric analyses of four wild-type and three sclerostin knockout mice demonstrated an increased width of the cementum and a concomitant moderate decrease in the periodontal space width.Taken together,these results suggest that the lack of sclerostin mainly alters the bone and cementum phenotypes rather than producing abnormalities in tooth structures such as dentin. | Ulrike Kuchler Uwe Y Schwarze Toni Dobsak Patrick Heimel Dieter D Bosshardt Michaela Kneissel Reinhard Gruber | 2014 | International Journal of Oral Science2014，6，2： | 7 |
| 3 | Comparative Transcriptomic Analysis of Salt Adaptation in Roots of Contrasting Medicago truncatula Genotypes显示文摘进化差异能被和不同环境的植物的相互作用驾驶。涉及生态的改编到不能生活的限制的分子的底能用 genomic 工具被探索。荚是世界范围的主要庄稼,土壤咸度是在这些植物影响产量的一个主要压力。我们在 Medicago truncatula 荚分析了让对比回答腌应力的二遗传型的根 transcriptome:TN1.11,在咸突尼斯的土壤,和参考 Jemalong A17 遗传型取样了。TN1.11 植物在盐应力以及钠离子的微分累积下面看增加的根生长是否与 A17 相比。Transcriptomic 分析揭示了盐优先地在 TN1.11 的根顶调整的特定的基因簇,尤其是那些与植物生长素小径有关并且到在 histone 变体 isoforms 的变化。编码抄写因素(TF ) 的许多基因也是响应盐在二遗传型之间调整的差别。在为功能的研究选择的那些之中,在大多数差别在遗传型之间调整了的 bHLH 类型 TF 的 A17 遗传型的根的 overexpression 显著地在盐应力下面改进了根生长。尽管有微分 transcriptional 回答的全球复杂性,我们建议这 bHLH TF 表情的增加可以被连接到 M 的改编。truncatula 到盐的土壤环境。 | Ons Zahaf Sandrine Blanchet Axel de Zelicourt Benoit Alunni Julie Plet Carole Laffont Laura de Lorenzo Sandrine Imbeaud Jean-Laurent lchante Anouck Diet Mounawer Badri Ana Zabalza Esther M. Gonzalez Herve Delacroix Veronique Gruber Florian Frugier Martin Crespi | 2012 | Molecular Plant2012，5，5： | 7 |
| 4 | Sodium Citrate: A Universal Reducing Agent for Reduction/ Decoration of Graphene Oxide with Au Nanoparticles显示文摘一个灵巧的方法为减少的 graphene 氧化物 nanosheets (RGONS ) 的合成被建议,使用 graphene 氧化物并且 Au 减少 nanoparticle 的 graphene 氧化物 nanosheet (Au-RGONS ) 混血儿材料(去) 作为先锋和钠柠檬酸盐作为 reductant 和 stabilizer。产生 RGONS 和 Au-RGONS 混血儿材料被紫外力的光谱学描绘, X 光检查光电子光谱学, Fourier 变换红外线的光谱学,拉曼光谱学,原子力量显微镜学,传播电子显微镜学,和 X 光检查衍射。RGONS 和 Au-RGONS 混血儿材料通过在剩余之间的氢契约形成了稳定的胶体的分散,这被发现 RGONS 的表面和钠柠檬酸盐的 hydroxyl/carboxyl 组上的包含氧的功能。到三种 biomolecules 的 RGONS 和 Au-RGONS 混合的修改材料的玻璃质的碳电极(GCE ) 的电气化学的回答被调查,并且所有相对赤裸的 GCE 在电气化学的性能他们显示出显著增加。 | Zhe Zhang Huihui Chen Chunyan Xing Mingyi Guo Fugang Xu Xiaodan Wang Hermann J. Gruber Bailin Zhang Jilin Tang | 2011 | Nano Research2011，4，6： | 5 |
| 5 | Caffeic acid phenethyl ester protects against oxidative stress and dampens inflammation via heme oxygenase 1显示文摘Periodontal disease is associated with chronic oxidative stress and inflammation. Caffeic acid phenethyl ester(CAPE), which is a potent inducer of heme oxygenase 1(HO1), is a central active component of propolis, and the application of propolis improves periodontal status in diabetic patients. Here, primary murine macrophages were exposed to CAPE. Target gene expression was assessed by whole-genome microarray, RT-PCR and Western blotting. The antioxidative and anti-inflammatory activities of CAPE were examined by exposure of the cells to hydrogen peroxide, saliva and periodontal pathogens. The involvement of HO1 was investigated with the HO1 inhibitor tin protoporphyrin(SnPP) and knockout mice for Nrf2, which is a transcription factor for detoxifying enzymes. CAPE increased HO1 and other heat shock proteins in murine macrophages. A p38 MAPK inhibitor and Nrf2 knockout attenuated CAPE-induced HO1 expression in macrophages. CAPE exerted strong antioxidative activity. Additionally, CAPE reduced the inflammatory response to saliva and periodontal pathogens. Blocking HO1 decreased the antioxidative activity and attenuated the anti-inflammatory activity of CAPE. In conclusion, CAPE exerted its antioxidative effects through the Nrf2-mediated HO1 pathway and its anti-inflammatory effects through NF-κB inhibition. However, preclinical models evaluating the use of CAPE in periodontal inflammation are necessary in future studies. | Alexandra St?hli Ceeneena Ubaidha Maheen Franz Josef Strauss Sigrun Eick Anton Sculean Reinhard Gruber | 2019 | International Journal of Oral Science2019，11，1： | 4 |
| 6 | First performance evaluation of a dual-source CT (DSCT) system显示文摘 | Thomas G. Flohr Cynthia H. McCollough Herbert Bruder Martin Petersilka Klaus Gruber Christoph Sü? Michael Grasruck Karl Stierstorfer Bernhard Krauss Rainer Raupach Andrew N. Primak Axel Küttner Stefan Achenbach Christoph Becker Andreas Kopp Bernd M. Ohnes | 2006 | European Radiology2006，，6： | 3 |
| 7 | 瞄准靶心,搭弓射箭——创业者社会构念与认知构念的连接机制显示文摘创业研究围绕社会因素和认知因素形成了两大研究流派,为理解创业现象做出了各自独立的贡献。目前虽有部分社会因素与认知因素交叉的创业研究,但我们对创业的社会认知依然缺乏全面的认识。本文在创业情境中探索了社会因素和认知因素的交叉点,从而获得对创业社会认知的总体理解。社会因素通常是创业认知的基础,对其忽视或将其视为创业认知的外部因素会低估社会因素在整个创业过程中对个人思考、感觉和行为方式所潜在的巨大影响。因此,探讨创业的社会认知具有重要意义。 | Dean A.Shepherd Holger Patzelt Marc Gruber Sucheta Nadkarni 罗银燕(翻译) 林道谧(校订) | 2021 | 管理学季刊2021，6，3： | 3 |
| 8 | MicroRNA in rectal cancer显示文摘In rectal cancer,one of the most common cancers worldwide,the proper staging of the disease determines the subsequent therapy.For those with locally advancedrectal cancer,a neoadjuvant chemoradiotherapy(CRT) is recommended before any surgery.However,response to CRT ranges from complete response(responders) to complete resistance(non-responders).To date we are not able to separate in advance the first group from the second,due to the absence of a valid biomarker.Therefore all patients receive the same therapy regardless of whether they reap benefits.On the other hand almost all patients receive a surgical resection after the CRT,although a watch-and-wait procedure or an endoscopic resection might be sufficient for those who responded well to the CRT.Being highly conserved regulators of gene expression,micro RNAs(mi RNAs) seem to be promising candidates for biomarkers.Many studies have been analyzing the mi RNAs expressed in rectal cancer tissue to determine a specific mi RNA profile for the ailment.Unfortunately,there is only a small overlap of identified mi RNAs between different studies,posing the question as to whether different methods or differences in tissue storage may contribute to that fact or if the results simply are not reproducible,due to unknown factors with undetected influences on mi RNA expression.Other studies sought to find mi RNAs which correlate to clinical parameters(tumor grade,nodal stage,metastasis,survival) and therapy response.Although several mi RNAs seem to have an impact on the response to CRT or might predict nodal stage,there is still only little overlap between different studies.We here aimed to summarize the current literature on rectal cancer and mi RNA expression with respect to the different relevant clinical parameters. | azadeh azizian jens gruber b michael ghadimi jochen gaedcke | 2016 | World Journal of Gastrointestinal Oncology2016，8，5： | 3 |
| 9 | 不同启动子驱动下acdS基因转化烟草及耐盐性研究显示文摘acdS基因编码产生ACC脱氨酶,该酶属于脱巯基家族,可以降低逆境乙烯的合成量。利用农杆菌介导的叶盘法将CaMV35S-2启动子和rolD启动子驱动下的acdS基因转入烟草NC89叶片中。在含有卡那霉素的MS培养基上筛选得到Kanr转化烟草。通过PCR、Southern blotting对得到的Kanr转基因烟草进行分析,结果表明,acdS基因已经整合到了烟草的基因组中。对转基因烟草的RT-PCR及cDNA进行测序分析表明,acdS基因能够正确转录。对转基因烟草进行耐盐性测定,结果显示,与对照相比,两种启动子驱动下的转基因烟草耐盐性均有增强。但是rolD启动子驱动下的转基因植株的耐盐性最强。 | 秦智慧 刘艳昆 孙彦 康俊梅 王凭青 Margaret Gruber 白永琴 | 2010 | 生物技术通报2010，26，10： | 3 |
| 10 | Bigtable显示文摘 | Fay Chang Jeffrey Dean Sanjay Ghemawat Wilson C. Hsieh Deborah A. Wallach Mike Burrows Tushar Chandra Andrew Fikes Robert E. Gruber | 2008 | ACM Transactions on Computer Systems (TOCS)2008，，2： | 3 |
| 11 | 超高强混凝土中各组分与聚羧酸系超塑化剂之间的相互作用(英文)显示文摘超高强混凝土(ultra-high strength concrete,UHSC)的水灰比小于0.25,含有大量的硅灰等微细组分,这有利于颗粒的最优紧密堆积。硅灰的表面化学效应以及较大的表面积使其成为UHSC中最难被分散的组分。由甲基丙烯酸、甲基丙烯酸酯及甲代烯丙基磺酸合成的聚羧酸系超塑化剂能使水泥颗粒被有效润湿,然而烯丙醚-马来酸酐合成的聚羧酸系超塑化剂可以很好地分散硅灰。这2种不同的聚羧酸系超塑化剂的复合可以使其拥有不同的分子结构,从而赋予超高强混凝土很好的流动性。当只加入1种聚羧酸系超塑化剂时其掺量为1%(质量分数,下同),而当加入这种复合聚羧酸系超塑化剂时掺量为0.5%就足够了。这2种类型的聚羧酸系超塑化剂的协同效应是由于它们的选择性吸附:甲基丙烯酸盐基的聚羧酸系超塑化剂主要吸附在水泥颗粒表面,而烯丙醚基聚羧酸系超塑化剂主要吸附在硅灰颗粒表面。实验表明:小分子量的有机酸阴离子(如:柠檬酸盐、葡萄糖酸盐及酒石酸盐中的阴离子)与聚羧酸系超塑化剂之间具有潜在的协同作用。只需加入0.1%的这些阴离子即可显著提高烯丙醚基聚羧酸系超塑化剂的作用效果。这些阴离子可以起到一种辅助作用,它们同时吸附在水泥颗粒表面以及硅灰颗粒表面。水泥颗粒的表面首先由这些阴离子所占据,而硅灰颗粒表面吸附了烯丙醚基聚羧酸系超塑化剂和这些阴离子。这些阴离子起到了一种很强的静电分散效应,使烯丙醚基聚羧酸系超塑化剂的空间位阻效应得到加强。虽然聚羧酸系超塑化剂阴离子具有缓凝作用,但是使用这种复合聚羧酸系仍能制备出高早强混凝土。 | SCHROFL C GRUBER M PLANK J | 2010 | 硅酸盐学报2010，38，9： | 3 |
| 12 | Toward principles for the design of ontologies used for knowledge sharing 显示文摘 | GRUBER T | 1994 | Human Computer Studies1994，43，56： | 2 |
| 13 | 肾细胞癌肝转移的多次经动脉化疗栓塞术后局部控制及生存疗效的评价显示文摘本研究的目的是评价经动脉化疗栓塞(TACE)对肾细胞癌(RCC)肝脏转移灶的局部治疗及生存的效果。采用前瞻洼的研究方法,评价1999--2005年22例病人经TACE治疗的效果。45%的病人仅用丝裂霉素作为化疔药物,55%的病人同时使用丝裂霉索与吉西他滨(gemcitabine)。所有病例的栓塞材料均为碘化油和可降解淀粉微球。采用MRI评价局部治疗反应,并参照实体肿瘤治疗效果评价标准(RECIST)做出判断。用KM法计算平均和中位生存时间、 | M. Nabil T. Gruber D. Yakoub H. Ackermann S. Zangos T.J. Vogl. 邢艳(译) 刘文亚(校) 唐光健(校) | 2008 | 国际医学放射学杂志2008，31，5： | 2 |
| 14 | Highly Efficient miRNA-Mediated Reprogramming of Mouse and Human Somatic Cells to Pluripotency显示文摘 | Frederick Anokye-Danso Chinmay M. Trivedi Denise Juhr Mudit Gupta Zheng Cui Ying Tian Yuzhen Zhang Wenli Yang Peter J. Gruber Jonathan A. Epstein Edward E. Morrisey | 2011 | Cell Stem Cell2011，，4： | 2 |
| 15 | Crowd-out 10 years later: Have recent public insurance expansions crowded out private health insurance?显示文摘 | Jonathan Gruber Kosali Simon | 2007 | Journal of Health Economics2007，，2： | 2 |
| 16 | Calculation of Risk of Colorectal and Endometrial Cancer Among Patients With Lynch Syndrome显示文摘 | Elena Stoffel Bhramar Mukherjee Victoria M. Raymond Nabihah Tayob Fay Kastrinos Jennifer Sparr Fei Wang Prathap Bandipalliam Sapna Syngal Stephen B. Gruber | 2009 | Gastroenterology2009，，5： | 2 |
| 17 | The Treatment of Intertrochanteric Fractures: Results Using an Intramedullary Nail With Integrated Cephalocervical Screws and Linear Compression显示文摘 | Andreas H Ruecker M Rupprecht M Gruber M Gebauer F Barvencik D Briem J M Rueger | 2009 | Journal of Orthopaedic Trauma2009，，1： | 2 |
| 18 | Creep Modeling of Magnesia-chromite Bricks in a RH Snorkel During a Process Cycle显示文摘In this paper both experimental and analytical approaches to provide the inputs for creep modeling of refractories including a newly developed high temperature compressive creep machine and an inverse estimation procedure of creep law parameters are briefly introduced.Besides,a modified shear test is applied to determine the cohesion and friction angle of refractories under shear state. A RH snorkel equipped with magnesia- chromite bricks is chosen for a case study of thermomechanical simulation applying the classical creep model and Drucker-Prager creep model available in the finite element code ABAQUS,respectively. Afterwards,thermal stresses and joint opening of magnesia- chromite bricks during a process cycle are compared to distinguish the impact of these two creep models. | JIN Shengli Harald HARMUTH Dietmar GRUBER Roman RSSLER | 2015 | China's Refractories2015，24，1： | 2 |
| 19 | 钢包预热过程热应力影响因子及预报模型显示文摘运用有限元软件ABAQUS建立钢包包衬的线性弹性模型,模拟钢包预热过程包衬的热应力,分析包衬厚度及其材料物理性能对包衬内最大热应力和钢壳表面温度的影响;采用偏最小二乘法建立包衬厚度及材料物理性能与包衬内最大热应力、钢壳表面温度间的预报模型。结果表明,工作衬材料物理性能对包衬最大应力和钢壳表面温度起主要影响作用;较之于无绝热衬,有绝热衬钢包永久衬材料物理性能对钢包热应力和钢壳表面温度的影响作用显著降低。 | 金胜利 Harald Harmuth Dietmar Gruber Thomas Auer 李亚伟 | 2011 | 武汉科技大学学报2011，34，1： | 2 |
| 20 | Quantitation of viral DNA by real-time PCR applying duplex amplification, internal standardization, and two-color fluorescence detection 显示文摘 | Gruber F Falkner F G Domer F | 2001 | Appl Environ Mierobiol2001，67，6： | 1 |
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