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| 1 | 湖南芙蓉锡矿床锡矿石和有关花岗岩的^(40)Ar-^(39)Ar年龄及其地球动力学意义显示文摘在研究和介绍湖南芙蓉锡矿矿床地质特征的基础上 ,对云英岩型锡矿石中的白云母和与成矿有关的骑田岭角闪黑云花岗岩中的黑云母进行了40 Ar_3 9Ar年龄测定 ,获得角闪黑云花岗岩的坪年龄为 (1 5 7.5± 0 .3)Ma;三门云英岩锡矿石的坪年龄为 (1 5 6 .1± 0 .4 )Ma ;淘洗窝云英岩锡矿石的坪年龄 (1 6 0 .1± 0 .9)Ma。这 3组测年数据很一致 ,不仅精确地反应出成岩成矿的时间限制 ,而且表明了花岗岩成岩与锡矿成矿的密切关系。此外 ,三组数据坪年龄一致显示出 ,在成岩成矿之后矿体未受到后期热事件的扰动。芙蓉锡矿床是湘南大型钨锡多金属矿集区的组成部分 ,也是华南地区中生代钨锡成矿两大高峰期之一的 1 6 0~ 1 35Ma期间形成的代表性矿床 。 | 毛景文 李晓峰 Bernd Lehmann 陈文 蓝晓明 魏绍六 | 2004 | 矿床地质2004，23，2： | 138 |
| 2 | Growth-Regulating Factors (GRFs): A Small Transcription Factor Family with Important Functions in Plant Biology显示文摘调整生长的因素(GRF ) 是原来在茎和叶开发为他们的角色被识别的植物特定的抄写因素,但是最近的研究加亮他们为在不利环境条件下面包括生长过程的花和种子形成,根发展,和协作的另外的中央发展过程同样重要。几 GRF 的表达式被 microRNA miR396 控制,并且 GRF-miRNA396 规章的模块看起来对几这些进程中央。另外, GRF 和 miR396 在上游的抄写因素被发现了,并且下游地逐渐地指向 GRF 的基因被解开。这里,我们考察 GRF 执行的生物功能的当前的知识并且调查可得到的分子的数据说明他们怎么在细胞的水平施加角色。 | Mohammad Amin Omidbakhshfard Sebastian Proost Ushio Fujikura Bernd Mueller-Roeber | 2015 | Molecular Plant2015，8，7： | 51 |
| 3 | 哀牢山-红河剪切带左行走滑作用起始时间约束--点苍山高温糜棱岩的显微构造与热年代学证据显示文摘位于哀牢山-红河剪切带NW延伸方向上的点苍山变质杂岩体遭受强烈的左行走滑剪切变形、变质作用改造,岩石中保存了典型的高温矿物组合以及由它们构成的宏观和微观高温变形构造特征,其中糜棱岩中具有极其发育的长石矿物拉伸线理而形成典型的L与LS型构造岩是其一个明显的特征。本文对点苍山地区高温糜棱岩主要矿物开展了显微构造与矿物变形、变形机制及组构分析,并对于遭受高温糜棱岩化改造的一个花岗质岩体开展了SHRIMP锆石U-Pb定年分析。结果表明岩石中长石、角闪石、石英等主要矿物具有典型的达角闪岩相条件下的高温晶质塑性变形和动态生长特征,它们也为走滑剪切变形活动提供了充分的微观构造证据。对于点苍山高温糜棱岩化改造的眼球状或似斑状二长花岗岩的显微构造分析结果表明,这套花岗质岩石从走滑剪切前期岩浆的侵位之后经历了早期强烈的岩浆期后交代作用—亚岩浆流动—高温固态塑性剪切变形的递进演化过程。由此可见,岩浆的上升与就位受左行走滑剪切作用的制约,岩体又遭受了强烈剪切变形改造。同时对这套构造前期就位花岗质岩石中的锆石进行定年分析,获得33.88±0.32Ma的岩浆结晶年龄,为此,我们有充分的理由认为,在点苍山地区哀牢山-红河剪切带左行走滑剪切作用的起始时间至少应该为早渐新世30.88±0.32Ma。 | 曹淑云 刘俊来 Bernd LEISS Axel VOLLBRECHT 邹运鑫 赵春强 | 2009 | 地质学报2009，83，10： | 42 |
| 4 | 塔里木河下游胡杨林胸径结构及林木分布特征显示文摘采用'面'上宏观调查与'点'上典型研究相结合,集中对塔里木河下游阿拉干断面100hm2的胡杨(Populus euphratica)林木分布与胸径结构进行了调查。结果发现,在距河道0-20m的范围内,胸径为0-4cm的幼龄胡杨占最多,达到13.24%。以后随着离河道距离的增加,幼龄胡杨所占比例逐渐减小。胸径分布范围简单,胸径为16-36cm的林木株数在胡杨林中所占的比例最多。另外,随着离河道距离的增加,胸径在48cm以上的过熟林和衰老林的比例逐渐增多。距河道0-200m的范围内,胡杨分布占整个胡杨林的80%以上。其中以疏失度为0-50%的长势较好的胡杨为主。在200-400m的范围内,疏失度为50%-75%的长势较差的过熟林和衰老林的比例开始增多。距河道400m以上,胡杨密度开始急剧下降,胡杨株数所占的比例几乎下降到5%以下。 | 王金山 哈力克.玉米提 Bernd Cyffka 吾斯曼.库尔班 彭树宏 | 2008 | 植物学通报2008，25，6： | 30 |
| 5 | 云南昆阳磷矿黑色页岩微量元素特征及其地质意义显示文摘昆阳磷矿是我国下寒武统黑色页岩中赋存的最大的磷块岩矿床。为了探讨磷块岩及上覆黑色页岩的源区性质及古海洋的氧化还原环境,本文对梅树村组中谊村段的磷块岩、石岩头段的黑色页岩以及筇竹寺组玉案山段的砂质黑色页岩的地层剖面进行了岩石地球化学研究。发现昆阳剖面磷矿区的下寒武统黑色页岩Th-Zr和Th-Y/Ho比值以及Y-Y/Ho比值与陆源碎屑物质更为接近,石岩头段黑色页岩样品的稀土元素总量平均为174×10-6,与大陆壳稀土总量的平均丰度基本一致。稀土配分模式也十分类似,说明陆源碎屑物质来源比海水自生来源占的比重更大。受陆源碎屑物质的影响,Ni/Co,V/Cr和V/(V+Ni)等氧化还原敏感元素比值并不能很好的指示古海洋的沉积环境。但石岩头段黑色页岩的氧化还原敏感元素相对大陆壳具有一定程度的富集,并且富集程度不强烈,Ce具有轻微的负异常,反映了黑色页岩可能形成于次氧化环境。 | 徐林刚 Bernd LEHMANN 张锡贵 郑伟 孟庆田 | 2014 | 岩石学报2014，30，6： | 30 |
| 6 | Experimental study on dehydration melting of natural biotite-plagioclase gneiss from High Himalayas and implications for Himalayan crust anatexis显示文摘Here we present the results of dehydration melting, melt morphology and fluid migration based on the dehydration melting experiments on natural bio-tite-plagioclase gneiss performed at the pressure of 1.0-1.4 GPa, and at the temperature of 770-1028℃. Experimental results demonstrate that: (i) most of melt tends to be distributed along mineral boundaries forming 'melt film' even the amount of melt is less than 5 vol%; melt connectivity is controlled not only by melt topology but also by melt fraction; (ii) dehydration melting involves a series of subprocesses including subsoiidus dehydration reaction, fluid migration, vapor-present melting and vapor-absent melting; (iii) experiments produce peraluminous granitic melt whose composition is similar to that of High Himalayan leucogranites (HHLG) and the residual phase assemblage is Pl+Qz+ Gat+Bio+Opx±Cpx+IIm/Rut±Kfs and can be comparable with granulites observed in Himalayas. The experiments provide the evidence that biotite-plagioclase gneiss is one of | YANG Xiaosong JIN Zhenmin Ernst Huenges Frank R.Schilling Bernd Wunder | 2001 | Chinese Science Bulletin2001，46，10： | 27 |
| 7 | Gut microbiome,liver immunology,and liver diseases显示文摘The gut microbiota is a complex and plastic consortium of microorganisms that are intricately connected with human physiology.The liver is a central immunological organ that is particularly enriched in innate immune cells and constantly exposed to circulating nutrients and endotoxins derived from the gut microbiota.The delicate interaction between the gut and liver prevents accidental immune activation against otherwise harmless antigens.Work on the interplay between the gut microbiota and liver has assisted in understanding the pathophysiology of various liver diseases.Of immense importance is the step from high-throughput sequencing(correlation)to mechanistic studies(causality)and therapeutic intervention.Here,we review the gut microbiota,liver immunology,and the interaction between the gut and liver.In addition,the impairment in the gut-liver axis found in various liver diseases is reviewed here,with an emphasis on alcohol-associated liver disease(ALD),nonalcoholic fatty liver disease(NAFLD),and autoimmune liver disease(AILD).On the basis of growing evidence from these preclinical studies,we propose that the gut-liver axis paves the way for targeted therapeutic modalities for liver diseases. | Rui Wang Ruqi Tang Bo Li Xiong Ma Bernd Schnabl Herbert Tilg | 2021 | Cellular & Molecular Immunology2021，18，1： | 23 |
| 8 | Feasibility and safety of autologous bone marrow mononuclear cell transplantation in patients with advanced chronic liver disease显示文摘AIM: To evaluate the safety and feasibility of bone marrow cell (BMC) transplantation in patients with chronic liver disease on the waiting list for liver transplantation. METHODS: Ten patients (eight males) with chronic liver disease were enrolled to receive infusion of autologous bone marrow-derived cells. Seven patients were classified as Child-Pugh B and three as Child-Pugh C. Baseline assessment included complete clinical and laboratory evaluation and abdominal MRI. Approximately 50 ml of bone marrow aspirate was prepared by centrifugation in a ficoll-hypaque gradient. At least of 100 millions of mononuclear-enriched BMCs were infused into the hepatic artery using the routine technique for arterial chemoembolization for liver tumors. Patients were followed up for adverse events up to 4 mo. RESULTS: The median age of the patients was 52 years (range 24-70 years). All patients were discharged 48 h after BMC infusion. Two patients complained ofmild pain at the bone marrow needle puncture site. No other complications or specific side effects related to the procedure were observed. Bilirubin levels were lower at 1 (2.19 ± 0.9) and 4 mo (2.10 ± 1.0) after cell transplantation that baseline levels (2.78 ± 1.2). Albumin levels 4 mo after BMC infusion (3.73 ± 0.5) were higher than baseline levels (3.47 ± 0.5). International normalized ratio (INR) decreased from 1.48 (SD = 0.23) to 1.43 (SD = 0.23) one month after cell transplantation. CONCLUSION: BMC infusion into hepatic artery of patients with advanced chronic liver disease is safe and feasible. In addition, a decrease in mean serum bilirubin and INR levels and an increase in albumin levels are observed. Our data warrant further studies in order to evaluate the effect of BMC transplantation in patients with advanced chronic liver disease. | Andre Castro lyra Milena Botelho Pereira Soares luiz Flavio Maia da Silva Marcos Fraga Fortes André Goyanna Pinheiro Silva Augusto César de Andrade Mota Sheilla A Oliveira Eduardo lorens Braga Wilson Andrade de Carvalho Bernd Genser Ricardo Ribeiro dos Santos luiz Guilherme Costa lyra | 2007 | World Journal of Gastroenterology2007，13，7： | 21 |
| 9 | 中国沿海两例食用织纹螺中毒事件中织纹螺体内毒素分析显示文摘近年来,因食用织纹螺(Nassariusspp.)导致的中毒事件在中国沿海屡有发生。由于中毒患者的症状与麻痹性贝毒中毒症状相似,因此,许多中毒事件被归咎于麻痹性贝毒,认为织纹螺中的毒素与邻近海域的有毒赤潮有关,但也有研究发现螺体内存在河豚毒素。对此,本研究应用亲水性相互作用色谱柱建立了河豚毒素的液相色谱-质谱联用分析方法,对造成2002年和2003年两次中毒事件的织纹螺样品进行分析。结果表明,两批织纹螺样品中均含有高浓度的河豚毒素及其衍生物,包括三脱氧河豚毒素、脱水河豚毒素和单加氧河豚毒素等,而且两个织纹螺样品中的毒素组成非常相似。因此,导致这两起中毒事件的致毒因子是河豚毒素及其衍生物。江苏和福建两地织纹螺中毒素组成的相似性显示两地织纹螺可能具有相同或相近的毒素来源。 | 于仁成 周名江 李爱峰 张清春 王云峰 李钧 颜天 Michael Quilliam Bernd Luckas | 2007 | 中国水产科学2007，14，5： | 21 |
| 10 | 青藏高原中部全新世气候变化的湖泊沉积地球化学记录显示文摘通过青藏高原中部兹格塘错湖泊沉积物总碳(TC)、总有机碳(TOC)、总氮(TN)、总硫(TS)、氢指数(HI)、氧指数(OI)和有机质的碳同位素(δ^13Corg)等多项指标的综合分析,在判断沉积物中有机质来源的基础上,根据各指标的变化特征阐明了各自的气候指示意义,建立了兹格塘错全新世以来的古气候演化序列.10100 cal a BP兹格塘错地区进入全新世,全新世早中期为暖湿气候特征,在8600~8400和7400~7000 cal a BP发生两次强烈冷事件;中晚全新世以来气候变冷变干.这一气候演化过程与其邻近的错鄂的研究结果相近,代表了青藏高原中部全新世的气候演化特点.青藏高原中部全新世气候变化主要受太阳辐射控制. | 吴艳宏 Andreas Lücke Bernd Wünnemann 李世杰 王苏民 | 2007 | 中国科学(D辑)2007，37，9： | 21 |
| 11 | 胡杨部分生态指标对塔里木河下游应急输水的响应显示文摘向塔里木河下游应急生态输水对于胡杨为主体的荒漠河岸植被的恢复和自然更新产生了积极的影响。本文根据近5年对塔里木河下游阿拉干地区的大量野外调查数据,分析了应急输水对该地区地下水位上升及胡杨各项生态指标的影响。结果显示:随着应急生态输水的继续和扩大,塔河下游典型监测断面——阿拉干的地下水位逐渐抬升,水质得到改善,河道附近的地下水埋深已经由输水前的10~12m抬升至5.5~6.2m。胡杨的部分生态指标对输水有不同程度的响应;具体表现在,在垂直河道方向上,离河道越近胡杨各项生态指标,即盖度、郁闭度、冠幅、萌生枝、树冠疏失度以及次生苗和实生苗出现的频率等对输水的响应越显著。总体来说,在河道200m范围之内,生态输水对胡杨恢复的影响程度是显著的;在200~800m之间,为中度影响;800m以上的距离几乎无影响。 | 玉米提·哈力克 柴政 艾里西尔·库尔班 Bernd Cyffka 任伟 | 2009 | 资源科学2009，31，8： | 21 |
| 12 | 北五味子化学成分研究显示文摘目的对北五味子进行进一步化学研究。方法采用色谱和光谱法分离鉴定北五味子的化学成分。结果分离得到四个化合物,分别鉴定为甘五酸(ganwuwe izic ac id,Ⅰ),富马酸单乙酯(mono-ethyl fum arate,Ⅱ),二十四烷酸(tetracosanoicac id,Ⅲ),内消旋二氢愈疮木酸(m eso-d ihydroguaiaretic ac id,Ⅳ)。结论Ⅰ,Ⅱ,Ⅲ均为首次从该植物中分离得到,Ⅳ的13CNMR数据为首次报道。 | 王丽薇 周长新 Bernd Schneider 赵昱 | 2006 | 中国现代应用药学2006，23，5： | 21 |
| 13 | Split liver transplantation: Current developments显示文摘In 1988, Rudolf Pichlmayr pioneered split liver transplantation(SLT), enabling the transplantation of one donor liver into two recipients-one pediatric and one adult patient. In the same year, Henri Bismuth and colleagues performed the first full right/full left split procedure with two adult recipients. Both splitting techniques were rapidly adopted within the transplant community. However, a SLT is technically demanding, may cause increased perioperative complications, and may potentially transform an excellent deceased donor organ into two marginal quality grafts. Thus, crucial evaluation of donor organs suitable for splitting and careful screening of potential SLT recipients is warranted. Furthermore, the logistic background of the splitting procedure as well as the organ allocation policy must be adapted to further increase the number and the safety of SLT. Under defined circumstances, in selected patients and at experienced transplant centers, SLT outcomes can be similar to those obtained in full organ LT. Thus, SLT is an important tool to reduce the donor organ shortage and waitlist mortality, especially for pediatric patients and small adults. The present review gives an overview of technical aspects, current developments, and clinical outcomes of SLT. | Christina Hackl Katharina M Schmidt Caner Süsal Bernd Dohler Martin Zidek Hans J Schlitt | 2018 | World Journal of Gastroenterology2018，24，47： | 20 |
| 14 | 环境质量评价中的生物指示与生物监测显示文摘通过比较生物指示与生物监测技术和仪器分析技术的分析过程及原理,结合北京市土壤中土壤脲酶与土壤重金属含量之间的相关关系的案例,及生物指示与生物监测技术在水生生态系统及大气污染研究中的应用状况,系统阐述了生物指示与生物监测技术研究的发展历程、研究前沿及发展方向。指出定量校正及不同学科与地区的科学团队的合作是生物指示与生物监测技术研究中需要克服的关键问题,并提出生物指示与生物监测技术研究的目标是整合不同学科的研究方向,为人类健康与环境安全的保护与预测提供技术支持。 | Bernd Markert 王美娥 Simone Wünschmann 陈卫平 | 2013 | 生态学报2013，33，1： | 19 |
| 15 | ORS1, an H2O2-Responsive NAC Transcription Factor, Controls Senescence in Arabidopsis thaliana显示文摘我们这里报导那 ORS1,一以前, NAC 抄写因素家庭,的 uncharacterized 成员在 Arabidopsis thaliana 控制叶老朽。ORS1 的 Overexpression 在转基因的植物加速老朽,而它的抑制推迟它。ORS1 下游地行动的基因被全球表示分析用生产 dexamethasone 可诱导的 ORS1GR 熔化蛋白质的转基因的植物识别。42 起来调整的基因,(70%) 30 以前被显示在年龄依赖者老朽期间起来调整。我们也观察到(76%) 32 ORS1 依赖的基因被导致由长期(4 d ) ,然而并非短期(6 h ) 咸度应力(150 公里 NaCl ) 。而且,分别地, 16 和 24 基因的表示与氢过氧化物(H2O2 ) 在处理的 1 和 5 h 以后被导致,知道在咸度应力期间积累的反应的氧种。ORS1 本身被发现到被 H2O2 处理很快并且强烈在叶子和根导致。在 vitro 绑定地点选择使用,我们决定了 ORS1 的比较喜欢的有约束力的主题并且发现了它在 ORS1 依赖的基因的一半在场。ORS1 是 ORE1/ANAC092/AtNAC2 的 paralog,叶老朽的一个以前报导的管理者。种系发生的 footprinting 在不同 Brassicaceae 种类揭示了 ORS1 和 ORE1 倡导者序列的进化保存,显示强壮的积极选择对两基因起作用。我们结束那 ORS1,同样到 ORE1,通过可以与咸依赖者、 H2O2 依赖的发信号的小径包含串音的一个规章的网络的联系老朽的基因的扳机表示。 | Salma Balazadeh Miroslaw Kwasniewski Camila Caldana Mohammad Mehrnia Maria Ines Zanor Gang-Ping Xue Bernd Mueller-Roeber | 2011 | Molecular Plant2011，4，2： | 19 |
| 16 | TRPV1 activation improves exercise endurance and energy metabolism through PGC-1α upregulation in mice显示文摘 | Zhidan Luo Liqun Ma Zhigang Zhao Hongbo He Dachun Yang Xiaoli Feng Shuangtao Ma Xiaoping Chen Tianqi Zhu Tingbing Cao Daoyan Liu Bernd Nilius Yu Huang Zhencheng Yan Zhiming Zhu | 2012 | Cell Research2012，22，3： | 18 |
| 17 | 冰川物质平衡模式及其对比研究——以祁连山黑河流域十一冰川研究为例显示文摘冰川物质平衡是冰川连结气候和水资源的纽带,对其的观测和模拟始终是冰川与气候变化研究领域的重点和前缘之一.以祁连山黑河流域十一冰川为参照冰川,结合实测物质平衡验证资料,建立了基于冰川表面能量平衡的冰川物质平衡模型(物理模型)和基于温度参数、温度-辐射参数和温度-辐射-水汽压参数的三种度日因子模型(统计模型),并对模拟结果进行了分析及评估.结果表明:净辐射是冰川表面最主要的能量来源,占能量收入的82.3%;其次为感热供热,占收入的17.7%.净长波辐射基本为负,吸收的热量主要通过融化和蒸发/升华方式消耗,分别占能量支出的84.7%和15.3%.加入净短波辐射和水汽压参数的度日因子-物质平衡模型的模拟效果提高显著,相对误差为7%,与能量平衡模型的模拟误差6.7%,相差不大.研究表明,能量-物质平衡模型的物理意义明确,模拟能力强大,尤其在日尺度上有绝对的优势;统计物质平衡模型在特定的地理条件和气候条件下表现出不佳,对于一些极端值的模拟能力欠缺,但是具有输入变量少,计算简单的优点.研究结果对黑河流域乃至整个祁连山地区的冰川物质平衡模拟方法的建立具有参考意义. | 方潇雨 李忠勤 Bernd Wuennemann 高抒 陈仁升 | 2015 | 冰川冻土2015，37，2： | 18 |
| 18 | 如何认识体验经济显示文摘一、体验经济的提出
自1998年美国Strategic Horizons LLP公司两位创始人B.Joseph Pine和JamesH.Gilmore在同年<哈佛商业评论>(Harvard Business Review)7/8月号期刊上发表<欢迎进入体验经济>(Welcome to the experience economy)一文以及1999年由哈佛商学院出版社出版两人合著的<体验经济>(The Experience Economy)一书以来,体验经济的提法日益受到人们的关注,尤其是在IT业更是备受青睐.然而值得回味的是,在之前近30年,著名未来学家阿尔文·托夫勒于1970年在其所著的<未来的冲击>一书中,虽早已提到继服务业发展之后,体验业将成为经济的支柱,但一直没有引起人们的注意.究其原因,一方面是因为托夫勒先生虽然提到继服务经济发展之后体验经济将会出现,但没有象前面提到的两位美国企业家那样作深入细致的分析;另一方面更重要的原因在于,世纪之交一系列经济和社会环境的变化,使得体验经济的重提,恰逢其时.那么有哪些变化使得体验经济的概念在世界范围内能够迅速传播呢?大致说来,主要有以下几个方面: | 祝合良 Bernd H.Schmitt | 2002 | 首都经济贸易大学学报2002，4，5： | 18 |
| 19 | Immunobiology and immunotherapy of HCC:spotlight on innate and innate-like immune cells显示文摘Immune-based therapies such as immune checkpoint inhibitors have revolutionized the systemic treatment of various cancer types.The therapeutic application of monoclonal antibodies targeting inhibitory pathways such as programmed cell death-1(PD-1)/programmed cell death ligand 1(PD-L1)and CTLA-4 to cells of the adaptive immune system has recently been shown to generate meaningful improvement in the clinical outcome of hepatocellular carcinoma(HCC).Nevertheless,current immunotherapeutic approaches induce durable responses in only a subset of HCC patients.Since immunologic mechanisms such as chronic inflammation due to chronic viral hepatitis or alcoholic and nonalcoholic fatty liver disease play a crucial role in the initiation,development,and progression of HCC,it is important to understand the underlying mechanisms shaping the unique tumor microenvironment of liver cancer.The liver is an immunologic organ with large populations of innate and innate-like immune cells and is exposed to bacterial,viral,and fungal antigens through the gut-liver axis.Here,we summarize and highlight the role of these cells in liver cancer and propose strategies to therapeutically target them.We also discuss current immunotherapeutic strategies in HCC and outline recent advances in our understanding of how the therapeutic potential of these agents might be enhanced. | Benjamin Ruf Bernd Heinrich Tim F.Greten | 2021 | Cellular & Molecular Immunology2021，18，1： | 18 |
| 20 | Holocene climate change in the Central Tibetan Plateau inferred by lacustrine sediment geochemical records显示文摘Multi-proxies of lacustrine sediments, such as total carbon (TC), total organic carbon (TOC), total inorganic carbon (TIC), total nitrogen (TN), total sulfur (TS), hydrogen index (HI), oxygen index (OI) and stable carbon isotopic composition of organic matter (δ 13Corg), were analyzed using a 7.3 m core from Zigê Tangco. The source of the organic matter in the sediment was mainly from autochthonous phytoplankton, therefore the significances of proxies can be interpreted as that high TOC, TOC/TS, HI and δ13Corg values, low TC, TIC values corresponded to warm and wet climatic condition, and vice versa. The process of climatic development in the Zigê Tangco region was hence recovered. During the early and Mid-Holocene, the climate was warm and wet and intensive cold events occurred during the periods of 8600 to 8400 cal a BP and 7400 to 7000 cal a BP. In the second half of Holocene, the climate became cold and dry gradually. The palaeoclimatic process during Holocene in Zigê Tangco region matched well with that in Co Ngoin region which is ca 40 km to the south-east. Therefore this palaeoclimatic process represents the Holocene climatic feature in the Central Tibetan Plateau which has the same pattern in the Northern Tibetan Plateau, but the time and duration of some climatic events might be different. We can conclude that in Holocene solar insolation controlled the climatic pattern on the central Tibetan Plateau. | Andreas LüCKE Bernd WüNNEMANN | 2007 | Science China Earth Sciences2007，50，10： | 16 |
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