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| 1 | Gastroenteropancreatic neuroendocrine tumours显示文摘 | Irvin M Modlin Kjell Oberg Daniel C Chung Robert T Jensen Wouter W de Herder Rajesh V Thakker Martyn Caplin Gianfranco Delle Fave Greg A Kaltsas Eric P Krenning Steven F Moss Ola Nilsson Guido Rindi Ramon Salazar Philippe Ruszniewski Anders Sundin | 2008 | Lancet Oncology2008，，1： | 8 |
| 2 | Differences in outcomes of oesophageal and gastric cancer surgery across Europe显示文摘 | J. L. Dikken J. W. van Sandick W. H. Allum J. Johansson L. S. Jensen H. Putter V. H. Coupland M. W. J. M. Wouters V. E. P. Lemmens C. J. H. van de Velde | 2012 | Br J Surg2012，，1： | 4 |
| 3 | Prediction of delayed graft function using different scoring algorithms: A single-center experience显示文摘AIM To compare the performance of 3 published delayed graftfunction(DGF) calculators that compute the theoretical risk of DGF for each patient.METHODS This single-center,retrospective study included 247 consecutive kidney transplants from a deceased donor.These kidney transplantations were performed at our institution between January 2003 and December 2012.We compared the occurrence of observed DGF in our cohort with the predicted DGF according to three different published calculators. The accuracy of the calculators was evaluated by means of the c-index(receiver operating characteristic curve).RESULTS DGF occurred in 15.3% of the transplants under study.The c index of the Irish calculator provided an area under the curve(AUC) of 0.69 indicating an acceptable level of prediction,in contrast to the poor performance of the Jeldres nomogram(AUC = 0.54) and the Chapal nomogram(AUC = 0.51). With the Irish algorithm the predicted DGF risk and the observed DGF probabilities were close. The mean calculated DGF risk was significantly different between DGF-positive and DGF-negative subjects(P < 0.0001). However,at the level of the individual patient the calculated risk of DGF overlapped very widely with ranges from 10% to 51% for recipients with DGF and from 4% to 56% for those without DGF.The sensitivity,specificity and positive predictive value of a calculated DGF risk ≥ 30% with the Irish nomogram were 32%,91% and 38%. CONCLUSION Predictive models for DGF after kidney transplantation are performant in the population in which they were derived,but less so in external validations. | Magda Michalak Kristien Wouters Erik Fransen Rachel Hellemans Amaryllis H Van Craenenbroeck Marie M Couttenye Bart Bracke Dirk K Ysebaert Vera Hartman Kathleen De Greef Thiery Chapelle Geert Roeyen Gerda Van Beeumen Marie-Paule Emonds Daniel Abramowicz Jean-Louis Bosmans | 2017 | World Journal of Transplantation2017，7，5： | 3 |
| 4 | Near-infrared fluorescence guided esophageal reconstructive surgery: A systematic review显示文摘BACKGROUND After an esophagectomy, the stomach is most commonly used to restore continuity of the upper gastrointestinal tract. These esophago-gastric anastomoses are prone to serious complications such as leakage associated with high morbidity and mortality. Graft perfusion is considered to be an important predictor for anastomotic integrity. Based on the current literature we believe Indocyanine green fluorescence angiography(ICGA) is an easy assessment tool for gastric tube(GT) perfusion, and it might predict anastomotic leakage(AL).AIM To evaluate feasibility and effectiveness of ICGA in GT perfusion assessment and as a predictor of AL.METHODS This study was designed according to the PRISMA guidelines and registered in the PROSPERO database. PubMed and EMBASE were independently searched by 2 reviewers for studies presenting data on intraoperative ICGA GT perfusion assessment during esophago-gastric reconstruction after esophagectomy.Relevant outcomes such as feasibility, complications, intraoperative surgical changes based on ICGA findings, quantification attempts, anatomical data and the impact of ICGA on postoperative anastomotic complications, were collected by 2 independent researchers. The quality of the included articles was assessed based on the Methodological Index for Non-Randomized Studies. The 19 included studies presented data on 1192 esophagectomy patients, in 758 patients ICGA was used perioperative to guide esophageal reconstruction.RESULTS The 19 included studies for qualitative analyses all described ICGA as a safe and easy method to evaluate gastric graft perfusion. AL occurred in 13.8% of the entire cohort, 10% in the ICG guided group and 20.6% in the control group(P <0.001). When poorly perfused cases are excluded from the analyses, the difference in AL was even larger(AL well-perfused group 6.3% vs control group 20.5%, P <0.001). The AL rate in the group with an altered surgical plan based on the ICG image was 6.5%, similar to the well perfused group(6.3%) and significantly less than the poorly perfused group(47.8%)(P < 0.001), suggesting that the technique is able to identify and alter a potential bad outcome.CONCLUSION ICGA is a safe, feasible and promising method for perfusion assessment. The lower AL rate in the well perfused group suggest that a good fluorescent signal predicts a good outcome. | Elke Van Daele Yves Van Nieuwenhove Wim Ceelen Christian Vanhove Bart P Braeckman Anne Hoorens Jurgen Van Limmen Oswald Varin Dirk Van de Putte Wouter Willaert Piet Pattyn | 2019 | World Journal of Gastrointestinal Oncology2019，11，3： | 3 |
| 5 | Magnetic Resonance Imaging Surveillance Detects Early-Stage Pancreatic Cancer in Carriers of a p16-Leiden Mutation显示文摘 | Hans F.A. Vasen Martin Wasser Anneke van Mil Rob A. Tollenaar Marja Konstantinovski Nelleke A. Gruis Wilma Bergman Frederik J. Hes Daniel W. Hommes G. Johan A. Offerhaus Hans Morreau Bert A. Bonsing Wouter H. de Vos tot Nederveen Cappel | 2011 | Gastroenterology2011，，3： | 3 |
| 6 | ENETS Consensus Guidelines for the Management of Patients with Digestive Neuroendocrine Neoplasms: Functional Pancreatic Endocrine Tumor Syndromes显示文摘 | Jensen Robert T Cadiot Guillaume Brandi Maria L De Herder Wouter W Kaltsas Gregory Komminoth Paul Scoazec Jean-yves Salazar Ramon Sauvanet Alain Kianmanesh Reza | 2012 | Neuroendocrinology2012，，2： | 3 |
| 7 | Consensus on the definition of colorectal anastomotic leakage: A modified Delphi study显示文摘BACKGROUND Despite the emerging knowledge about colorectal anastomotic leakage(CAL)through the increasing number of clinical and experimental studies, there is no generally accepted definition of CAL. Because of the wide variety of definitions used in literature, comparison of study outcomes and quality of care is complicated.AIM To reach consensus on the definition of CAL using a modified Delphi method.METHODS The RAND/UCLA appropriateness method was used. The expert panel consisted of international colorectal surgeons and researchers who had published three or more articles about CAL. The consensus process consisted of two online distributed questionnaires and a third round with a recommendation. In the questionnaires participants were asked to rate the appropriateness of statements using a 1-9 Likert scale. Consensus was defined as a panel median between 1-3 or 7-9 without disagreement. In the final round a recommendation was formed regarding the definition of CAL and the expert panel was asked if they agreed or disagreed.RESULTSTwenty-three authors participated in the first round and twenty-one finished the second round. After two rounds consensus was reached on 37 items(80%) in nine different categories. The International Study Group of Rectal Cancer definition is the most frequently advised general definition by our panel. Consensus was reached regarding the clinical symptoms of CAL, which serum markers contributes to the suspicion of CAL, which radiological and perioperative findings should be considered as CAL, which grading system is appropriate and if there should be a range of postoperative days in the definition. Eventually, 19 experts completed all three rounds of which 16(84%) agreed with our final recommendations for the definition of CAL.CONCLUSION A consensus-based recommendation for the definition of CAL was formed using our modified Delphi method that can be widely incorporated in the field. | Claire PM van Helsdingen Audrey CHM Jongen Wouter J de Jonge Nicole D Bouvy Joep PM Derikx | 2020 | World Journal of Gastroenterology2020，26，23： | 3 |
| 8 | Effects of regular physical activity on defecation pattern in middle-aged patients complaining of chronic constipation显示文摘 | Anneke M. De Schryver Yolande C. Keulemans Harry P. Peters Louis M. Akkermans André J. Smout Wouter R. De Vries Gerard P. Van Berge-Henegouwen | 2005 | Scandinavian Journal of Gastroenterology2005，，4： | 2 |
| 9 | Statins and risk of incident diabetes: a collaborative meta-analysis of randomised statin trials显示文摘 | Naveed Sattar David Preiss Heather M Murray Paul Welsh Brendan M Buckley Anton JM de Craen Sreenivasa Rao Kondapally Seshasai John J McMurray Dilys J Freeman J Wouter Jukema Peter W Macfarlane Chris J Packard David J Stott Rudi G Westendorp James Shepherd | 2010 | The Lancet2010，，9716： | 2 |
| 10 | Faster Recovery of Gastrointestinal Transit After Laparoscopy and Fast-Track Care in Patients Undergoing Colonic Surgery显示文摘 | Sjoerd van Bree Malaika Vlug Willem Bemelman Markus Hollmann Dirk Ubbink Koos Zwinderman Wouter de Jonge Susanne Snoek Karen Bolhuis Esmerij van der Zanden Frans The Roel Bennink Guy Boeckxstaens | 2011 | Gastroenterology2011，，3： | 2 |
| 11 | Lymphatic spread, nodal count and the extent of lymphadenectomy in cancer of the colon显示文摘 | Wouter Willaert Marc Mareel Dirk Van De Putte Yves Van Nieuwenhove Piet Pattyn Wim Ceelen | 2014 | Cancer Treatment Reviews2014，，3： | 2 |
| 12 | Proton Pump Inhibitors Partially Restore Mucosal Integrity in Patients with PPI-responsive Esophageal Eosinophilia but not Eosinophilic Esophagitis显示文摘 | Bram D. van Rhijn Pim W. Weijenborg Joanne Verheij Marius A. van den Bergh Weerman Caroline Verseijden René M.J.G.J. van den Wijngaard Wouter J. de Jonge Andreas J.P.M. Smout Albert J. Bredenoord | 2014 | Clinical Gastroenterology and Hepatology2014，，： | 2 |
| 13 | Oocytes in the empty follicle: a controversial syndrome显示文摘 | Mustafa Aktas Nicole G. Beckers Wouter G. van Inzen Arie Verhoeff Diederick de Jong | 2005 | Fertility and Sterility2005，，： | 2 |
| 14 | CETP as a Target in HDL-raising Therapy:lessons from APOE*3-Leiden. CETP Transgenic Mice显示文摘Background Cardiovascular disease (CVD) is mainly caused by atherosclerosis,for which dyslipidemia (i.e. high (V)LDL-cholesterol (C),high triglycerides and low HDLC is a major risk factor. To reduce the risk to develop CVD,patients with dyslipidemia are usually treated with lipid-lowering drugs including statins and fibrates. | Willeke de Haan Jitske de Vries-van der Weij Caroline C. van der Hoogt José W.A. van der Hoorn Johannes A. Romijn J. Wouter Jukema Louis M. Havekes Hans M.G. Princen Patrick C.N. Rensen | 2009 | 中国动脉硬化杂志2009，17，7： | 2 |
| 15 | Statins and risk of incident diabetes: a collaborative meta-analysis of randomised statin trials显示文摘 | Naveed Sattar David Preiss Heather M Murray Paul Welsh Brendan M Buckley Anton JM de Craen Sreenivasa Rao Kondapally Seshasai John J McMurray Dilys J Freeman J Wouter Jukema Peter W Macfarlane Chris J Packard David J Stott Rudi G Westendorp James Shepherd | 2010 | The Lancet2010，，9716： | 2 |
| 16 | Patient-specific instruments for surgical resection of painful tarsal coalition in ado- lescents显示文摘 | De Wouters S Trau Duy K Docquier PL | 2014 | Orthop Traumatol Surg Res2014，100，42： | 1 |
| 17 | Protective effect of the bile salt hydrolase-active Lactobacillus reuteri against bile salt cytotoxicity 显示文摘 | De BOEVER P WOUTERS R VERSCHAEVE L | 2000 | Appl Microbiol Biotechnol2000，53，6： | 1 |
| 18 | Thoratic epidural anesthesia improves functional recovery from myocardial stunning in conscious dogs显示文摘 | Roll N Van de Voide M Wouters PF | 1996 | Anesth Analg1996，83，5： | 1 |
| 19 | p27kip1–838C>A Single Nucleotide Polymorphism Is Associated With Restenosis Risk After Coronary Stenting and Modulates p27kip1 Promoter Activity显示文摘 | Claudia M. van Tiel Peter I. Bonta Saskia Z.H. Rittersma Marcel A.M. Beijk Edward J. Bradley Anita M. Klous Karel T. Koch Frank Baas J Wouter Jukema Douwe Pons M Lourdes Sampietro Hans Pannekoek Robbert J. de Winter Carlie J.M. de Vries | 2009 | Circulation2009，，： | 1 |
| 20 | Subspace state space system identification for industrial processes 显示文摘 | Favoreel Wouter de Moor Bart van Overschee Peter | 2000 | Journal of Process Control2000，10，23： | 1 |
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