|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 汉语第三人称回指语形式眼动阅读实验显示文摘回指是篇章连贯的主要手段之一,受多种因素影响。前人文献较少关注回指语形式对回指的影响,而这正是汉语篇章的特色之一。本文运用眼动实验的范式考察汉语母语者阅读理解第三人称回指语形式(第三人称代词或零形式)的差异,包括认知加工时间的长短以及是否影响回指对象的判定,并对比相关语言学研究,旨在揭示汉语母语者理解篇章回指的机制。实验发现:1)汉语母语者阅读话题接续的篇章时,零形式快于代词;而阅读话题转换的篇章时,代词快于零形式。可见母语者对篇章连贯性和回指语形式之间的对应关系非常敏感,篇章连贯性和回指语形式之间有相互作用。2)不管是零形式还是代词,母语者都倾向认为其回指主语,即回指语形式不影响回指对象的判定,但读者会根据篇章的展开理解并修正对回指的判断,证明篇章回指的理解是一个动态的调整过程。 | 李榕 Pim MAK Ted SANDERS | 2016 | 中国语文2016，，1： | 10 |
| 2 | The Soil-Borne Identity and Microbiome-Assisted Agriculture:Looking Back to the Future显示文摘Looking forward includes looking back every now and then.In 2007,David Weller looked back at 30 years of biocontrol of soil-borne pathogens by Pseudomonas and signified that the progress made over decades of research has provided a firm foundation to formulate current and future research questions.It has been recognized for more than a century that soil-borne microbes play a significant role in plant growth and health.The recent application of high-throughput omics technologies has enabled detailed dissection of the microbial players and molecular mechanisms involved in the complex interactions in plant-associated microbiomes.Here,we highlight old and emerging plant microbiome concepts related to plant disease control,and address perspectives that modern and emerging microbiomics technologies can bring to functionally characterize and exploit plant-associated microbiomes for the benefit of plant health in future microbiome-assisted agriculture. | Peter A.H.M.Bakker Roeland L.Berendsen Johan A.Van Pelt Gilles Vismans Ke Yu Erqin Li Sietske Van Bentum Sanne W.M.Poppeliers Juan J.Sanchez Gil Hao Zhang Pim Goossens Ioannis A.Stringlis Yang Song Ronnie de Jonge CornéM.J.Pieterse | 2020 | Molecular Plant2020，13，10： | 3 |
| 3 | SNARE-RNAi Results in Higher Terpene Emission from Ectopically Expressed Caryophyllene Synthase in Nicotiana benthamiana显示文摘植物生产众多的萜烯和许多努力被奉献了给萜烯 biosynthetic 基因的鉴定和描述。然而,很少萜烯怎么在房间以内并且从房间被搬运进 apoplast 被知道。为了在这调查泡熔化的一个通常认为的角色,处理,我们使用了 Agrobacterium 在 Nicotiana benthamiana 的调停 tumefaciens 的短暂 coexpression ? 有也的 MtVAMP721e-RNAi 构造(Vi ) caryophyllene synthase 或沉香醇 synthase 分别地。叶子的 Headspace 分析证明那 caryophyllene 或沉香醇排出物增加了关于五倍什么时候 N.? benthamiana VAMP72 功能被堵住。RNA 定序和 agroinfiltrated N. 的蛋白质 ubiquitination 分析 ? benthamiana 叶摘录建议增加的萜烯排出物可以被归因于 proteasome 基于三观察失灵:离开 DsRed 标记蛋白质的高水平, TPS+Vi (1 ) 出现了,(2 ) ubiquitinated 蛋白质的高水平,并且(3 ) 多重 proteasome 基因的协调导致的表示,大概由调停 proteasome 的反馈规定的缺乏引起了。然而, caryophyllene 或沉香醇没禁止 proteasome 相关的朊酶活动在在里面 ? vitro 试金。当结果不为在萜烯运输的泡熔化的一个角色是最后的时,他们确实显示出在泡熔化和某些萜烯的宫外的表示的抑制之间的一个强壮的相互作用。结果在新陈代谢的工程有潜在的应用。 | Hieng-Ming Ting Thierry L. Delatte Pim Kolkman Johana C. Misas-Villamil Renier A.L. van der Hoom Harro J. Bouwmeester Alexander R. van der Krol | 2015 | Molecular Plant2015，8，3： | 2 |
| 4 | Validation study of postoperative liver failure and mortality risk scores after liver resection for perihilar cholangiocarcinoma显示文摘Background:Surgery for perihilar cholangiocarcinoma(PHCC)remains a challenging procedure with high morbidity and mortality.The Academic Medical Center(Amsterdam UMC)and Memorial Sloan Kettering Cancer Center proposed a postoperative mortality risk score(POMRS)and post-hepatectomy liver failure score(PHLFS)to predict patient outcomes.This study aimed to validate the POMRS and PHLFS for PHCC patients at Hokkaido University.Methods:Medical records of 260 consecutive PHCC patients who had undergone major hepatectomy with extrahepatic bile duct resection without pancreaticoduodenectomy at Hokkaido University between March 2001 and November 2018 were evaluated to validate the PHLFS and POMRS.Results:The observed risks for PHLF were 13.7%,24.5%,and 39.8%for the low-risk,intermediate-risk,and high-risk groups,respectively,in the study cohort.A receiver-operator characteristic(ROC)analysis revealed that the PHLFS had moderate predictive value,with an analysis under the curve(AUC)value of 0.62.Mortality rates based on the POMRS were 1.7%,5%,and 5.1%for the low-risk,intermediate-risk,and high-risk groups,respectively.The ROC analysis demonstrated an AUC value of 0.58.Conclusions:This external validation study showed that for PHLFS the threshold for discrimination in an Eastern cohort was reached(AUC>0.6),but it would require optimization of the model before use in clinical practice is acceptable.The POMRS were not applicable in the eastern cohort.Further external validation is recommended. | Takehiro Noji Satoko Uemura Jimme KWiggers Kimitaka Tanaka Yoshitsugu Nakanishi Toshimichi Asano Toru Nakamura Takahiro Tsuchikawa Keisuke Okamura Pim BOlthof William RJarnagin Thomas Mvan Gulik Satoshi Hirano | 2022 | Hepatobiliary Surgery and Nutrition2022，11，3： | 2 |
| 5 | High-Resolution Spiral Computed Tomography Coronary Angiography in Patients Referred for Diagnostic Conventional Coronary Angiography显示文摘 | Nico R. Mollet Filippo Cademartiri Carlos A.G. van Mieghem Giuseppe Runza Eugène P. McFadden Timo Baks Patrick W. Serruys Gabriel P. Krestin Pim J. de Feyter | 2005 | Circulation2005，，15： | 2 |
| 6 | Influence of Organo-Metal Interactions on Regeneration of Exhausted Clay Mineral Sorbents in Soil Columns Loaded with Heavy Metals显示文摘Natural clay minerals can play an important role in crude remediation of wastewater polluted with the heavy metals(HMs) Cu, Zn and Ni. The presence and timing of addition of natural dissolved organic matter(DOM) have a significant effect on the HM removal by clay mineral sorbents. However, the influence of the presence of DOM on the remediation of the used clay mineral sorbents once saturated with HMs is largely unknown. To resolve this, clay mineral-rich soil column of varying composition, loaded(i) with Cu, Zn and Ni only,(ii) first with DOM followed by Cu, Zn and Ni, or(iii) with DOM, Cu, Zn and Ni simultaneously, was used in a set of desorption experiments. The soil columns were leached with 0.001 mol L^(-1)CaCl_2 dissolved in water as control eluent and 0.001 mol L^(-1)CaCl_2 dissolved in DOM as treatment eluent. During the preceding loading phase of the sorbent, the timing of DOM addition(sequential or concurrent with HMs) was found to have a significant influence on the subsequent removal of the HMs. In particular when the column was loaded with DOM and HMs simultaneously, largely irreversible co-precipitation took place. Our results indicate that the regeneration potential of clay mineral sorbents in wastewater treatment will be significantly reduced when the treated water is rich in DOM. In contrast, in manured agricultural fields(where HMs enter together with DOM), HM mobility will be lower than expected from interaction dynamics of HMs and clay minerals. | Yasser REFAEY Boris JANSEN Pim DE VOOGT John R.PARSONS Abdel-Hamid EL-SHATER Abdel-Aziz EL-HADDAD Karsten KALBITZ | 2017 | Pedosphere2017，27，3： | 2 |
| 7 | 荷兰水质与空气质量监测的发展现状显示文摘 | 张明顺 Pim Hamminga | 2006 | 环境监测管理与技术2006，18，3： | 2 |
| 8 | Proton Pump Inhibitors Partially Restore Mucosal Integrity in Patients with PPI-responsive Esophageal Eosinophilia but not Eosinophilic Esophagitis显示文摘 | Bram D. van Rhijn Pim W. Weijenborg Joanne Verheij Marius A. van den Bergh Weerman Caroline Verseijden René M.J.G.J. van den Wijngaard Wouter J. de Jonge Andreas J.P.M. Smout Albert J. Bredenoord | 2014 | Clinical Gastroenterology and Hepatology2014，，： | 2 |
| 9 | Fractional Flow Reserve Versus Angiography for Guiding Percutaneous Coronary Intervention in Patients With Multivessel Coronary Artery Disease显示文摘 | Nico H.J. Pijls William F. Fearon Pim A.L. Tonino Uwe Siebert Fumiaki Ikeno Bernhard Bornschein Marcel van't Veer Volker Klauss Ganesh Manoharan Thomas Engstr?m Keith G. Oldroyd Peter N. Ver Lee Philip A. MacCarthy Bernard De Bruyne | 2010 | Journal of the American College of Cardiology2010，，3： | 2 |
| 10 | Post-hepatectomy liver regeneration in the context of bile acid homeostasis and the gut-liver signaling axis显示文摘Background:Liver regeneration following partial hepatectomy(PHx)is a complicated process involving multiple organs and several types of signaling networks.The bile acid-activated metabolic pathways occupy an auxiliary yet important chapter in the entire biochemical story.PHx is characterized by rapid but transient bile acid overload in the liver,which constitutes the first wave of proliferative signaling in the remnant hepatocytes.Bile acids trigger hepatocyte proliferation through activation of several nuclear receptors.Following biliary passage into the intestines,enterocytes reabsorb the bile acids,which results in the activation of farnesoid X receptor(FXR),the consequent excretion of fibroblast growth factor(FGF)19/FGF15,and its release into the enterohepatic circulation.FGF19/FGF15 subsequently binds to its cognate receptor,fibroblast growth factor receptor 4(FGFR4)complexed withβ-klotho,on the hepatocyte membrane,which initiates the second wave of proliferative signaling.Because some bile acids are toxic,the remnant hepatocytes must resolve the potentially detrimental state of bile acid excess.Therefore,the hepatocytes orchestrate a bile acid detoxification and elimination response as a protective mechanism in concurrence with the proliferative signaling.The response in part results in the excretion of(biotransformed)bile acids into the canalicular system,causing the bile acids to end up in the intestines.Relevance for patients:Recently,FXR agonists have been shown to promote regeneration via the gut-liver axis.This type of pharmacological intervention may prove beneficial for patients with hepatobiliary tumors undergoing PHx.In light of these developments,the review provides an in-depth account of the pathways that underlie post-PHx liver regeneration in the context of bile acid homeostasis in the liver and the gut-liver signaling axis. | Lianne de Haan Sarah Jvan der Lely Anne-Loes K.Warps Quincy Hofsink Pim B.Olthof Mark J.de Keijzer Daniel A.Lionarons Lionel Mendes-Dias Bote G.Bruinsma Korkut Uygun Hartmut Jaeschke Geoffrey C.Farrell Narci Teoh Rowan Fvan Golen Tiangang Li Michal Heger | 2018 | Journal of Clinical & Translational Research2018，4，1： | 2 |
| 11 | The clinical significance of epidermal growth factor receptor (EGR-R) in human breast cancer: a review on 5232 patients 显示文摘 | Berns PMJJ Schmitz PIM etal | 1992 | Endocrine Rew1992，13，： | 1 |
| 12 | Nitric oxide contribute to the but does not modulate O^2 - consumption in exercising swine 显示文摘 | Dirk JD Rene S Pim AL et regulation of vasomotor tone al | 2000 | Cardiovascular Research2000，47，： | 1 |
| 13 | Thirty-day incidence and six-month clinical outcome of thrombotic stent occlusion after bare-metal, sirolimus, or paclitaxel stent implantation显示文摘 | Andrew T.L. Ong Angela Hoye Jiro Aoki Carlos A.G. van Mieghem Gaston A. Rodriguez Granillo Karel Sonnenschein Evelyn Regar Eugene P. McFadden Georgios Sianos Willem J. van der Giessen Peter P.T. de Jaegere Pim de Feyter Ron T. van Domburg Patrick W. Serru | 2005 | Journal of the American College of Cardiology2005，，6： | 1 |
| 14 | Environmental and economic costs of soil erosion and conservation benefits显示文摘 | Pim entel D Harvey C Resos udar mo P | 1995 | Science1995，267，： | 1 |
| 15 | Host range of Oidium lycopersici occurring in the Netherlands显示文摘 | Huang Caicheng Jeannette Biesheuvel Pim Lindhout | 2000 | European Journal of Plant Pathology2000，106，： | 1 |
| 16 | The role of the E6-p53 interaction in the molecular pathogenesis of HPV显示文摘 | Thomas M Pim D Banks L | 1999 | Oncogene1999，18，53： | 1 |
| 17 | Environmental Pollution显示文摘 | de Boer Jacob Wester Peter G van der Horst Aschwin Leonard Pim E G | 2003 | 122 : 632003，122，： | 1 |
| 18 | p53 polymorpHic variants at codon 72 exert different effects on cell cycle progression 显示文摘 | Pim D Banks L | 2004 | Int J Cancer2004，108，2： | 1 |
| 19 | Brominated flame retardants and perfluorinated compounds in indoor dust from homes and offices in Flanders, Belgium显示文摘 | Wendy D’Hollander Laurence Roosens Adrian Covaci Christa Cornelis Hans Reynders Karen Van Campenhout Pim de Voogt Lieven Bervoets | 2010 | Chemosphere2010，，4： | 1 |
| 20 | Cost-Effectiveness of Percutaneous Coronary Intervention in Patients With Stable Coronary Artery Disease and Abnormal Fractional Flow Reserve显示文摘 | William F. Fearon David Shilane Nico H.J. Pijls Derek B. Boothroyd Pim A.L. Tonino Emanuele Barbato Peter Jüni Bernard De Bruyne Mark A. Hlatky | 2013 | Circulation2013，，12： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员