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| 1 | Epidural anesthesia is effective for extracorporeal shock wave lithotripsy of pancreatic and biliary calculi显示文摘AIM: To evaluate the efficacy of thoracic epidural analgesia for extracorporeal shock wave lithotripsy (ESWL). METHODS: ESWL is an effective, non-invasive technique for the treatment of difficult pancreatic and large bile duct calculi. The procedure is often painful and requires large doses of analgesics. Many different anesthetic techniques have been used. Patients with either large bile duct calculi or pancreatic duct calculi which could not be extracted by routine endoscopic methods were selected. Thoracic epidural anesthesia (TEA) was routinely used in all the subjects unless contraindicated. Bupivacaine 0.25% with or without clonidine was used to block the segments D6 to D12. The dose was calculated depending on the age, height and weight of the patient. It was usually 1-2 mL per segment blocked.RESULTS: Ninety eight percent of the 1509 patients underwent ESWL under TEA. The subjects selected were within American Society of Anesthesiologists grade Ⅰ to Ⅲ. ESWL using EA permitted successful elimination of bile duct or pancreatic calculi with minimal morbidity. The procedure time was shorter in patients with TEA than in those who underwent ESWL under total intravenous anesthesia. CONCLUSION: Almost all patients undergoing ESWL with EA had effective blocks with a single catheter insertion and local anesthetic injection. | Santosh Darisetty Manu Tandan Duvvuru Nageshwar Reddy Rama Kotla Rajesh Gupta Mohan Ramchandani Sandeep Lakhtakia Guduru Venkat Rao Rupa Banerjee | 2010 | World Journal of Gastrointestinal Surgery2010，2，5： | 13 |
| 2 | Efficacy of low dose peginterferon alpha-2b with ribavirin on chronic hepatitis C显示文摘AIM: To assess the effi cacy of peginterferon alpha 2b at doses of 50 μg weekly and 80 μg weekly (based on body weight) plus ribavirin in HCV genotype 2 and genotype 3 chronic hepatitis C patients. METHODS: During the study period of Jan 2002 to Dec 2003, all patients diagnosed as chronic hepatitis C or HCV related compensated cirrhosis were treated with peginterferon alpha 2b 50 μg S/C weekly (body weight < 60 kg) or 80 μg S/C weekly (body weight > 60 kg) plus ribavirin 800 mg/d for 24 wk. RESULTS: Overall 28 patients, 14 patients in each group (based on body weight) were treated during the period. Out of 28 patients, 75% were genotype 3, 18% were genotype 2 and 7% were genotype 1. The mean dose of peginterferon alpha 2b was 0.91 μg/kg in group 1 and 1.23 μg/kg in group 2 respectively. The end of treatment and sustained virologic response rates were 82% and 78% respectively. Serious adverse effects were seen in 3.5% patients. CONCLUSION: Low dose peginterferon alpha 2b in combination with ribavirin for 24 wk is effective in HCV genotype 2 and 3 chronic hepatitis C patients. | Rajesh Gupta CH Ramakrishna Sandeep Lakhtakia Manu Tandan Rupa Banerjee D Nageshwar Reddy | 2006 | World Journal of Gastroenterology2006，12，34： | 10 |
| 3 | Endoscopic management of postcholecystectomy biliary leakage显示文摘BACKGROUND: Biliary leak is an uncommon but significant complication following cholecystectomy. Endotherapy is an established method of treatment. However, the optimal intervention is not known. METHOD: Eighty-five patients with postcholecystectomy biliary leaks from July 2000 to March 2009 were retrospectively evaluated. RESULTS: The study population was 20 males and 65 females with a mean age of 42.47 years. Patients presented with abdominal pain (46), jaundice (23), fever (23), abdominal distension (42), or bilious abdominal drain (67). Endoscopic retrograde cholangiopancreatography detected a leak at the cystic duct stump in 45 patients, stricture with middle common bile duct leak in 4, leak from the right hepatic duct in 3, and a ligated common bile duct in 32. Twelve also had bile duct stones. One had a broken T-tube with stones Endotherapy was possible in 53 patients. Three patients with stones, one with a broken T-tube with stones, and 4 with stricture of the common bile duct with a leak were managed with sphincterotomy and stenting. Eight patients with a cystic duct stump leak with stones were managed with sphincterotomy and stone extraction. Three outpatients and 12 inpatients with a cystic duct stump leak were managed with sphincterotomy and stent and sphincterotomy and nasobiliary drain, respectively. Five patients with a cystic duct stump leak were managed with stenting. Sixteen with coagulopathy were managed with only nasobiliary drain (9) or stent (7). Leak closure was achieved in 100% patients Four developed mild pancreatitis which improved with conservative treatment.CONCLUSIONS: Endoscopic intervention is a safe and effective method of treatment of postcholecystectomy biliary leaks. However, management should be individualized based on factors such as outpatients or inpatients, presence of stone, stricture, ligature, or coagulopathy. | Virendra Singh Gurpreet Singh Ganga R Verma Rajesh Gupta | 2010 | Hepatobiliary & Pancreatic Diseases International2010，9，4： | 9 |
| 4 | Contrast-free air cholangiography-assisted unilateral plastic stenting in malignant hilar biliary obstruction显示文摘BACKGROUND:Endoscopic palliation in malignant hilar biliary obstruction requires endoscopic retrograde cholangiopancreatography (ERCP),whereas contrast injection leads to cholangitis.Contrast-free metal stenting with or without magnetic resonance cholangiopancreatography (MRCP) has shown encouraging results,but MRCP and metal stents are costly.There have been no reports on the use of air cholangiography.METHODS:We prospectively evaluated the role of air cholangiography-assisted unilateral plastic stenting in 10 patients with type Ⅱ malignant hilar biliary obstruction.A retrospectively analysed group of 10 patients treated with contrast-free unilateral metal stenting served as historical controls.RESULTS:Ten patients with unresectable type Ⅱ malignant hilar biliary obstruction were studied.Air cholangiography detected type Ⅱ obstruction in all patients,similar to MRCP.The patients underwent unilateral stenting.Successful endoscopic drainage was achieved in all patients.The mean patency of the stent was 95.8±17.5 days in the study group and 143.9±115.1 days in the control group (P=0.20).The mean survival was 121.8±41.6 days in the study group and 154.9±122.5 days in the control group (P=0.42).KaplanMeier analysis showed an estimated median survival of 100:95% CI (65.9,134.1) days in the study group and 98:95% CI (84.1,111.9) days in the control group (P=0.62).Cholangitis occurred in none of the patients and there were no 30-day deaths nor major complications.Air cholangiographyassisted unilateral plastic stenting was cheaper than contrastfree unilateral metal stenting.CONCLUSION:Air cholangiography-assisted unilateral plastic stenting is as safe and effective as contrast-free unilateral metal stenting in type Ⅱ malignant hilar biliary obstruction for palliating patients,but it is cheaper. | Virendra Singh Gurpreet Singh Vikas Gupta Rajesh Gupta Rakesh Kapoor | 2010 | Hepatobiliary & Pancreatic Diseases International2010，9，1： | 7 |
| 5 | Predictors of Surgery in Patients With Severe Acute Pancreatitis Managed by the Step-Up Approach显示文摘 | Raghavendra Yalakanti Babu Rajesh Gupta Mandeep Kang Deepak Kumar Bhasin Surinder Singh Rana Rajinder Singh | 2013 | Annals of Surgery2013，，4： | 4 |
| 6 | Endoscopic radiofrequency ablation of cholangiocarcinoma: new palliative treatment modality (with videos)显示文摘 | Amitabh Monga Rajesh Gupta Mohan Ramchandani Guduru V. Rao Darisetty Santosh D. Nageshwar Reddy | 2011 | Gastrointestinal Endoscopy2011，，4： | 2 |
| 7 | Comparison of echocardiography and device based algorithm for atrio-ventricular delay optimization in heart block patients显示文摘AIM: To compare the atrio-ventricular(AV/PV) delay optimization by echocardiography and intra-cardiac electrocardiogram(IEGM) based Quick Opt algorithm in complete heart block(CHB) patients, implanted with a dual chamber pacemaker. METHODS: We prospectively enrolled 20 patients(age 59.45 ± 18.1 years; male: 65%) with CHB, who were implanted with a dual chamber pacemaker. The left ventricular outflow tract velocity time-integral was measured after AV/PV delay optimization by both echocardiography and Quick Opt algorithm method. Bland-Altman analysis was used for agreement between the two techniques. RESULTS: The optimal AV and PV delay determined by echocardiography was 155.5 ± 14.68 ms and 122.5 ± 17.73 ms(P < 0.0001), respectively and by Quick Opt method was 167.5 ± 16.73 and 117.5 ms ± 9.10 ms(P < 0.0001), respectively. A good agreement was observed between optimal AV and PV delay as measured by two methods. However, the correlation of the optimal AV(r = 0.0689, P = 0.77) and PV(r = 0.2689, P = 0.25) intervals measured by the two techniques was poor. The time required for AV/PV optimization was 45.26 ± 1.73 min by echocardiography and 0.44 ± 0.08 min by Quick Opt method(P < 0.0001).CONCLUSION: The programmer based IEGM method is an automated, quick, easier and reliable alternative to echocardiography for the optimization of AV/PV delay in CHB patients, implanted with a dual chamber pacemaker. | Rajesh Vijayvergiya Ankur Gupta | 2015 | World Journal of Cardiology2015，7，11： | 2 |
| 8 | 有胰 divisum 的 Choledochocele : 在磁性的回声 cholangiopancreatography 上诊断的稀罕同现显示文摘 We report a case of a 42-year-old male with symptomatic choledochocele and incidental pancreas divisum diagnosed with magnetic resonance cholangiopancreatography (MRCP). Small choledochocele is rare congenital malformation associated with non-specific symptoms and a delay in diagnosis. The coexistence of choledochocele and pancreas divisum is extremely rare with only two case reports published in literature. In both cases MRCP failed to diagnose any biliary or pancreatic abnormality. This case suggests that the patients with recurrent abdominal pain and pancreas divisum should not be presumed to be suffering from pancreatitis. Careful evaluated for additional anomalies in the biliary tree should be sought for refractory symptoms. MRCP is a useful one-stop-shop for diagnosing pancreatic and biliary ductal anomalies. | Yashwant Patidar Nitesh Agarwal Shailesh Gupta Ankur Arora Amar Mukund S Rajesh | 2013 | World Journal of Radiology2013，5，7： | 2 |
| 9 | In vivo evaluation of anti-oxidant and anti-lipidimic potential of Annona squamosa aqueous extract in Type 2 diabetic models显示文摘 | Rajesh Kumar Gupta Achyut Narayan Kesari Sandhya Diwakar Ameetabh Tyagi Vibha Tandon Ramesh Chandra Geeta Watal | 2008 | Journal of Ethnopharmacology2008，，1： | 2 |
| 10 | Role of <sup>18</sup> F ‐fluorodeoxyglucose positron emission tomography/computed tomography in the characterization of pancreatic masses: Experience from tropics显示文摘 | Sampath Santhosh Bhagwant Rai Mittal Deepak Bhasin Radhika Srinivasan Surinder Rana Ashim Das Ritambhra Nada Anish Bhattacharya Rajesh Gupta Rakesh Kapoor | 2013 | J Gastroenterol Hepatol2013，，2： | 2 |
| 11 | An overview of sustainability assessment methodologies显示文摘 | Rajesh Kumar Singh H.R. Murty S.K. Gupta A.K. Dikshit | 2008 | Ecological Indicators2008，，2： | 2 |
| 12 | Online Strategies for Dynamic Power Management in Systems with Multiple Power-Saving States显示文摘 | Sandy Irani Sandeep Shukla Rajesh Gupta | 2003 | ACM Transactions on Embedded Computing Systems2003，2，3： | 1 |
| 13 | Avinash joshi multiband hysteresis modulation and switching characterization for sliding-mode-controlled cascaded multilevel inverter显示文摘 | Rajesh Gupta Arindam Ghosh | 2010 | IEEE Transactions on Industry applications2010，57，7： | 1 |
| 14 | An overview of sustainability assessment Methodologies 显示文摘 | Rajesh K S Murty H R Gupta S K | 2009 | ecological indicator2009，9，： | 1 |
| 15 | Arterial pH,bicarbonate levels and base deficit at presentation as markers of predicting mortality in acute pancreatitis:a single-centre prospective study显示文摘Background.Arterial blood gas(ABG)parameters such as pH form part of multi-parameter scoring systems for predicting severe acute pancreatitis;however,literature on detailed evaluation of ABG alone in this context is scarce.Methods.Patients with acute pancreatitis presenting to our unit between January 2012 and November 2013 were prospectively studied.ABG analysis was done at admission and development of organ failure,any need for intervention,and mortality were noted.The association between various parameters of ABG analysis and the development of organ failure or local complications,need for interventions(endoscopic/radiological/surgical)and mortality were analysed.Results.Two hundred and five patients(mean age:39.33-13.85 years;61.0%males)were prospectively studied.The aetiology of acute pancreatitis was alcohol in 93 patients(45.4%)and gall stone disease in 73(35.6%).Organ failure developed in 71.2%patients and 83.9%had local complications.In 18%of patients,endoscopic/radiological/surgical interventions were needed and 14.6%died.The patients(n=35)with metabolic acidosis(pH<7.35)suffered higher frequency of organ failure,need for interventions and mortality.Patients with low arterial bicarbonate levels,as well as higher base deficit,also displayed higher frequency of organ failure,need for interventions and mortality.The receiver operating characteristic(ROC)curves for pH<7.35,bicarbonate<22 meq/L and base deficit of>4 meq/L for prediction of mortality were 0.771(95%CI:0.664–0.878),0.707(95%CI:0.622–0.791)and 0.780(95%CI:0.693–0.867),respectively.Conclusion.Arterial pH,bicarbonate levels,and base deficit at presentation are useful early markers for predicting adverse outcome in acute pancreatitis. | Vishal Sharma Thingbaijam Shanti Devi Ravi Sharma Puneet Chhabra Rajesh Gupta Surinder S.Rana Deepak K.Bhasin | 2014 | Gastroenterology Report2014，2，3： | 1 |
| 16 | Dynamic optimization of chemical processes using ant colony framework 显示文摘 | Rajesh J Gupta K Kusumakar H S | 2001 | Computers and Chemistry2001，25，6： | 1 |
| 17 | Multiband Hysteresis Modulation and Switching Characterization for Sliding-Mode-Controlled Cascaded Multilevel Inverter显示文摘 | Rajesh Gupta Arindam Ghosh Avinash Joshi | | 0，，07： | 1 |
| 18 | Midodrine in patients with cirrhosis and refractory or recurrent ascites: A randomized pilot study显示文摘 | Virendra Singh Sahdeb P. Dhungana Baljinder Singh Rajesh Vijayverghia Chander K. Nain Navneet Sharma Ashish Bhalla Pramod K. Gupta | 2011 | Journal of Hepatology2011，，2： | 1 |
| 19 | Molecular mapping and characterization of an RGA locus RGA Ptokin 1 -2171 in chickpea显示文摘 | Rajesh P N Tekeoglu M Gupta V S | 2002 | Euphytica2002，，128： | 1 |
| 20 | Hypoglycemic and antihyperglycemic activity of Aegle marmelos seed extract in normal and diabetic rats显示文摘 | Achyut Narayan Kesari Rajesh Kumar Gupta Santosh Kumar Singh Sandhya Diwakar Geeta Watal | 2006 | Journal of Ethnopharmacology2006，，3： | 1 |
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