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| 1 | Nature:揭示干细胞惊人异质性显示文摘论文作者George Daley教授说:"这是一项非常基础的研究,但它阐明了多能性状态广泛性。我们捕获了干细胞不同状态的详细分子谱。"研究人员通过采用多种变量如不同的化学物质、培养环境和遗传敲除来扰乱多能干细胞,研究人员探究了它们的发育景观。随后,他们分析了每个细胞的遗传组成,观察了每个细胞多能状态的微小波动。他们发现内部、化学和环境信号影响干细胞方式的许多细微差异,揭示出了复杂的发育调控因子"决策"回路。 | Roshan M.Kumar Patrick Cahan Alex K.Shalek Rahul Satija A.Jay Daley Keyser Hu Li Jin Zhang Keith Pardee David Gennert John J.Trombetta Thomas C.Ferrante Aviv Regev George Q.Daley James J. Collins | 2014 | 岭南现代临床外科2014，14，6： | 10 |
| 2 | Highly Efficient Reprogramming to Pluripotency and Directed Differentiation of Human Cells with Synthetic Modified mRNA显示文摘 | Luigi Warren Philip D. Manos Tim Ahfeldt Yuin-Han Loh Hu Li Frank Lau Wataru Ebina Pankaj K. Mandal Zachary D. Smith Alexander Meissner George Q. Daley Andrew S. Brack James J. Collins Chad Cowan Thorsten M. Schlaeger Derrick J. Rossi | 2010 | Cell Stem Cell2010，，5： | 4 |
| 3 | A striking local esophageal cytokine expression profile in eosinophilic esophagitis显示文摘 | Carine Blanchard Emily M. Stucke Beatriz Rodriguez-Jimenez Karen Burwinkel Margaret H. Collins Annette Ahrens Eileen S. Alexander Bridget K. Buckmeier Butz Sean C. Jameson Ajay Kaul James P. Franciosi Jonathan P. Kushner Philip E. Putnam J. Pablo Abonia M | 2010 | The Journal of Allergy and Clinical Immunology2010，，1： | 3 |
| 4 | Metals emitted from heavy-duty diesel vehicles equipped with advanced PM and NO X emission controls显示文摘 | Shaohua Hu Jorn D. Herner Martin Shafer William Robertson James J. Schauer Harry Dwyer John Collins Tao Huai Alberto Ayala | 2009 | Atmospheric Environment2009，，18： | 2 |
| 5 | Dry deposition of gaseous elemental mercury to plants and soils using mercury stable isotopes in a controlled environment显示文摘 | Andrew P. Rutter James J. Schauer Martin M. Shafer Joel E. Creswell Michael R. Olson Michael Robinson Ryan M. Collins Andrew M. Parman Tanya L. Katzman Justin L. Mallek | 2010 | Atmospheric Environment2010，，4： | 1 |
| 6 | Integrating Biological Redesign: Where Synthetic Biology Came From and Where It Needs to Go显示文摘 | Jeffrey C. Way James J. Collins Jay D. Keasling Pamela A. Silver | 2014 | Cell2014，，1： | 1 |
| 7 | Expanding role of 18F-fluoro-d-deoxyglucose PET and PET/CT in spinal infections显示文摘 | Filip Gemmel Paul C. Rijk James M. P. Collins Thierry Parlevliet Katrin D. Stumpe Christopher J. Palestro | 2010 | European Spine Journal2010，，4： | 1 |
| 8 | Transport impacts on atmosphere and climate: Shipping显示文摘 | Veronika Eyring Ivar S.A. Isaksen Terje Berntsen William J. Collins James J. Corbett Oyvind Endresen Roy G. Grainger Jana Moldanova Hans Schlager David S. Stevenson | 2009 | Atmospheric Environment2009，，37： | 1 |
| 9 | Design, synthesis and biological evaluation of α-substituted isonipecotic acid benzothiazole analogues as potent bacterial type II topoisomerase inhibitors显示文摘 | Lorraine C. Axford Piyush K. Agarwal Kelly H. Anderson Laura N. Andrau John Atherall Stephanie Barker James M. Bennett Michael Blair Ian Collins Lloyd G. Czaplewski David T. Davies Carlie T. Gannon Dushyant Kumar Paul Lancett Alastair Logan Christopher J. | 2013 | Bioorganic & Medicinal Chemistry Letters2013，，24： | 1 |
| 10 | Towards quantifying uncertainty in transient climate change显示文摘 | Matthew Collins Ben B. B. Booth Glen R. Harris James M. Murphy David M. H. Sexton Mark J. Webb | 2006 | Climate Dynamics (-)2006，，2： | 1 |
| 11 | Ultrasensitive Detection of KRAS2 Mutations in Bile and Serum from Patients with Biliary Tract Carcinoma Using LigAmp Technology显示文摘 | Chanjuan Shi Arjun Chandrasekaran Paul J. Thuluvath Collins Karikari Pedram Argani Michael Goggins Anirban Maitra James R. Eshleman | 2009 | The Journal of Molecular Diagnostics2009，，6： | 1 |
| 12 | Phase I Study of Single-Agent AZD1775 (MK-1775), a Wee1 Kinase Inhibitor, in Patients With Refractory Solid Tumors显示文摘 | Do Khanh Wilsker Deborah Ji Jiuping Zlott Jennifer Freshwater Tomoko Kinders Robert J. Collins Jerry Chen Alice P. Doroshow James H. Kummar Shivaani | 2015 | Journal of Clinical Oncology2015，，30： | 1 |
| 13 | Chlorinated dibenzo- p -dioxins, dibenzofurans, and biphenyl profiles of workers with trichlorophenol and pentachlorophenol exposures显示文摘 | James J. Collins Kenneth Bodner Salma Haidar Michael Wilken Carol J. Burns Les L. Lamparski Robert A. Budinsky Greg D. Martin Michael L. Carson | 2008 | Chemosphere2008，，1： | 1 |
| 14 | Reproducibility and changes in the apparent diffusion coefficients of solid tumours treated with combretastatin A4 phosphate and bevacizumab in a two-centre phase I clinical trial显示文摘 | Dow-Mu Koh Matthew Blackledge David J. Collins Anwar R. Padhani Toni Wallace Benjamin Wilton N. Jane Taylor J. James Stirling Rajesh Sinha Pat Walicke Martin O. Leach Ian Judson Paul Nathan | 2009 | European Radiology2009，，： | 1 |
| 15 | A Common Mechanism of Cellular Death Induced by Bactericidal Antibiotics显示文摘 | Michael A. Kohanski Daniel J. Dwyer Boris Hayete Carolyn A. Lawrence James J. Collins | 2007 | Cell2007，，5： | 1 |
| 16 | Identification, epidemiology, and chronicity of pediatric esophageal eosinophilia, 1982-1999显示文摘 | Charles W. DeBrosse Margaret H. Collins Bridget K. Buckmeier Butz Casey L. Allen Eileen C. King Amal H. Assa’ad J. Pablo Abonia Philip E. Putnam Marc E. Rothenberg James P. Franciosi | 2010 | The Journal of Allergy and Clinical Immunology2010，，： | 1 |
| 17 | Low-Density Lipoprotein and High-Density Lipoprotein Particle Subclasses Predict Coronary Events and Are Favorably Changed by Gemfibrozil Therapy in the Veterans Affairs High-Density Lipoprotein Intervention Trial显示文摘 | James D. Otvos Dorothea Collins David S. Freedman Irina Shalaurova Ernst J. Schaefer Judith R. McNamara Hanna E. Bloomfield Sander J. Robins | 2006 | Circulation2006，，12： | 1 |
| 18 | Highly Efficient Reprogramming to Pluripotency and Directed Differentiation of Human Cells with Synthetic Modified mRNA显示文摘 | Luigi Warren Philip D. Manos Tim Ahfeldt Yuin-Han Loh Hu Li Frank Lau Wataru Ebina Pankaj K. Mandal Zachary D. Smith Alexander Meissner George Q. Daley Andrew S. Brack James J. Collins Chad Cowan Thorsten M. Schlaeger Derrick J. Rossi | 2010 | Cell Stem Cell2010，，5： | 1 |
| 19 | Insights into the Origin of Water Soluble Organic Carbon in Atmospheric Fine Particulate Matter显示文摘 | David C. Snyder Andrew P. Rutter Ryan Collins Chris Worley James J. Schauer | 2009 | Aerosol Science and Technology2009，，11： | 1 |
| 20 | The Mortality Experience of Workers Exposed to 2,3,7,8-Tetrachlorodibenzo-p-dioxin in a Trichlorophenol Process Accident显示文摘 | James J. Collins Marcie E. Strauss George J. Levinskas Patrick R. Conner | 1993 | Epidemiology1993，，1： | 1 |
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