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| 1 | 心脏磁共振灌注成像用于冠状动脉疾病功能评价:与冠状动脉造影和血流储备分数的比较显示文摘Aims: Cardiac magnetic resonance perfusion imaging(CMRI) is a promising technique for non-invasive measurement of myocardial perfusion reserve. Fractional flowreserve(FFR) is an established invasive method for functional assessment of coronary artery disease(CAD). To prospectively assess the diagnostic value of CMRI for the detection of haemodynamically significant coronary lesions, compared with coronary angiography(CA) and FFR. Methods and results: Forty-three patients with suspected or known CAD underwent CA, CMRI, and FFR measurement. First pass magnetic resonance perfusion examination was performed during hyperaemia(140 μg/kg/min adenosine over 6 min) and at rest. One hundred and twenty-nine perfusion territories were assessed by semi-quantitative evaluation of signal intensity-time curves using the myocardial perfusion reserve index(MPRI)[upslopestress(corrected)/ upsloperest(corrected)]. Perfusion territories were categorized as normal(coronary stenosis≤50%), intermediate(stenosis >50%and FFR >0.75), or severe(stenosis >50%and FFR≤0.75 or total occlusion). MPRI values(±SD) were significantly different between the three categories[normal, 2.2±0.5 vs. intermediate, 1.8±0.5(P=0.005) and intermediate vs. severe, 1.2±0.3(P< 0.001)]. An MPRI cut-off value of 1.5(derived from receiver operating characteristics analysis) distinguished haemodynamically relevant(severe) from non-relevant(normal and intermediate) stenoses with a sensitivity of 88%(CI 74-100%)and a specificity of 90%(CI 84-96%). Conclusion: In contrast to earlier studies that compared CMRI with morphological examination(CA) alone, the present study compared CMRI with CA plus a standard invasive functional assessment(FFR) and demonstrated that CMRI is able to distinguish haemodynamically relevant from non-relevant coronary lesions with a high sensitivity and specificity and may therefore contribute to clinical decision-making. | Rieber J. Huber A. Erhard I. 郭俊 | 2006 | 世界核心医学期刊文摘(心脏病学分册)2006，，12： | 4 |
| 2 | Failure of Current Antibiotic First-Line Regimens and Mortality in Hospitalized Patients with Spontaneous Bacterial Peritonitis显示文摘 | A. Umgelter W. Reindl M. Miedaner R. M. Schmid W. Huber | 2009 | Infection2009，，1： | 3 |
| 3 | Premature ovarian failure: etiology and prospects显示文摘 | T. Laml I. Schulz-Lobmeyr A. Obruca J. C. Huber B. W. Hartmann | 2000 | Gynecological Endocrinology2000，，4： | 2 |
| 4 | Effectiveness of a procalcitonin algorithm to guide antibiotic therapy in respiratory tract infections outside of study conditions: a post-study survey显示文摘 | P. Schuetz M. Batschwaroff F. Dusemund W. Albrich U. Bürgi M. Maurer M. Brutsche A. R. Huber B. Müller | 2010 | European Journal of Clinical Microbiology & Infectious Diseases2010，，3： | 1 |
| 5 | Mammary Uptake, Portal-Drained Visceral Flux, and Hepatic Metabolism of Free and Peptide-Bound Amino Acids in Cows Fed Steam-Flaked or Dry-Rolled Sorghum Grain Diets显示文摘 | H. Tagari K. Webb B. Theurer T. Huber D. DeYoung P. Cuneo J.E.P. Santos J. Simas M. Sadik A. Alio O. Lozano A. Delgado-Elorduy L. Nussio C.M.M. Bittar F. Santos | 2008 | Journal of Dairy Science2008，，2： | 1 |
| 6 | Components of the interleukin-33/ST2 system are differentially expressed and regulated in human cardiac cells and in cells of the cardiac vasculature显示文摘 | Svitlana Demyanets Christoph Kaun Richard Pentz Konstantin A. Krychtiuk Sabine Rauscher Stefan Pfaffenberger Andreas Zuckermann Arezu Aliabadi Marion Gr?ger Gerald Maurer Kurt Huber Johann Wojta | 2013 | Journal of Molecular and Cellular Cardiology2013，，： | 1 |
| 7 | The synthesis of A21978C analogs byStreptomyces roseosporus cultivated under carbon limitation and fed fatty acids显示文摘 | F. M. Huber D. M. Berry R. L. Pieper A. J. Tietz | 1990 | Biotechnology Letters1990，，11： | 1 |
| 8 | The CIMT-monitoring panel: a two-step approach to harmonize the enumeration of antigen-specific CD8 + T lymphocytes by structural and functional assays显示文摘 | C. M. Britten C. Gouttefangeas M. J. P. Welters G. Pawelec S. Koch C. Ottensmeier A. Mander S. Walter A. Paschen J. Müller-Berghaus I. Haas A. Mackensen T. K?llgaard P. Straten M. Schmitt K. Giannopoulos R. Maier H. Veelken C. Bertinetti A. Konur C. Huber | 2008 | Cancer Immunology Immunotherapy2008，，3： | 1 |
| 9 | Capillary zone electrophoretic analysis of carbohydrates by direct and indirect UV detection显示文摘 | P. J. Oefner A. E. Vorndran E. Grill C. Huber G. K. Bonn | 1992 | Chromatographia (-)1992，，5： | 1 |
| 10 | Clinical impact of programmed cell death ligand 1 expression in colorectal cancer显示文摘 | Raoul A. Droeser Christian Hirt Carsten T. Viehl Daniel M. Frey Christian Nebiker Xaver Huber Inti Zlobec Serenella Eppenberger-Castori Alexander Tzankov Raffaele Rosso Markus Zuber Manuele Giuseppe Muraro Francesca Amicarella Eleonora Cremonesi Michael H | 2013 | European Journal of Cancer2013，，9： | 1 |
| 11 | TORE SUPRA experience of copper chromium zirconium electron beam welding显示文摘 | A. Durocher M. Lipa Ph. Chappuis J. Schlosser T. Huber B. Schedler | 2002 | Journal of Nuclear Materials2002，，： | 1 |
| 12 | The chronology of third molar mineralization in the Austrian population—a contribution to forensic age estimation显示文摘 | A. Meinl S. Tangl C. Huber B. Maurer G. Watzek | 2006 | Forensic Science International2006，，2： | 1 |
| 13 | Investigation into the shape selectivity of zeolite catalysts for biomass conversion显示文摘 | Jungho Jae Geoffrey A. Tompsett Andrew J. Foster Karl D. Hammond Scott M. Auerbach Raul F. Lobo George W. Huber | 2011 | Journal of Catalysis2011，，2： | 1 |
| 14 | Investigation into the shape selectivity of zeolite catalysts for biomass conversion显示文摘 | Jungho Jae Geoffrey A. Tompsett Andrew J. Foster Karl D. Hammond Scott M. Auerbach Raul F. Lobo George W. Huber | 2011 | Journal of Catalysis2011，，2： | 1 |
| 15 | FOCUS: A pilot study for national-scale critical loads development in the United States显示文摘 | Tamara F. Blett Jason A. Lynch Linda H. Pardo Cindy Huber Richard Haeuber Richard Pouyat | 2013 | Environmental Science and Policy2013，，： | 1 |
| 16 | Influence of updated guidelines on short- and long-term mortality in patients with non-ST-segment elevation acute coronary syndrome (NSTE-ACS)显示文摘 | B. Vogel S. Hahne I. Kozanli K. Kalla R. Jarai M. Freynhofer P. Smetana M. Nürnberg A. Geppert G. Unger K. Huber | 2011 | International Journal of Cardiology2011，，3： | 1 |
| 17 | Autoimmunity in viral myocarditis显示文摘 | Jay Reddy Chandirasegaran Massilamany Iwona Buskiewicz Sally A. Huber | 2013 | Current Opinion in Rheumatology2013，，4： | 1 |
| 18 | Tunable room-temperature cw laser action in Cr3+: GdScGa-Garnet显示文摘 | B. Struve G. Huber V. V. Laptev I. A. Shcherbakov E. V. Zharikov | 1983 | Applied Physics B Photophysics and Laser Chemistry1983，，3： | 1 |
| 19 | Side Effects of Phytoestrogens: A Meta-analysis of Randomized Trials显示文摘 | Clemens B. Tempfer Georg Froese Georg Heinze Eva-Katrin Bentz Lukas A. Hefler Johannes C. Huber | 2009 | The American Journal of Medicine2009，，10： | 1 |
| 20 | Splanchnic and Mammary Nitrogen Metabolism by Dairy Cows Fed Steam-Rolled or Steam-Flaked Corn显示文摘 | A. Delgado-Elorduy C.B. Theurer J.T. Huber A. Alio O. Lozano M. Sadik P. Cuneo H.D. De Young I.J. Simas J.E.P. Santos L. Nussio C. Nussio K.E. Webb H. Tagari | 2002 | Journal of Dairy Science2002，，1： | 1 |
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