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| 1 | 亚洲历史城市中心区遗产保护的真实性:在有关解释和成就中的假象显示文摘在历史建筑和历史地区保护中,确定真实性的原则和标准的目的是为规划应用和保护方法建立判断标准,对遗址和历史地区的文化资源管理进行策划。作者从这一角度出发,通过介绍不同流派对真实性的解释和体现手法,反映出关于遗产保护问题的各种矛盾。文章还以河内、槟城、新加坡和马尼拉等4个城市为例,分析东南亚地区对历史保护产生影响的环境条件,并进一步讨论了在这一地区遗产保护中有关真实性的问题。 | Fergus T. Maclaren M. E. Des | 2001 | 国外城市规划2001，16，4： | 12 |
| 2 | 加拿大遗产保护的实践以及有关机构显示文摘加拿大的遗产保护按国际、国家、省和地方等不同层次来进行。本文系统地描述了各个层次上的遗产保护机构及其职能,以及在各层次上开展的遗产保护实践活动,并介绍了有关立法和近年来的新发展动向。 | Fergus T. Maclaren | 2001 | 国外城市规划2001，16，4： | 9 |
| 3 | 谈伦理审查质量显示文摘针对伦理审查质量的含义进行了深入的剖析,对伦理审查质量体系的各个要素,包括法规框架,人员资质、独立性、管理和资源、审查工作的一致性和可预见性、明晰的职责流程等进行了逐一解释,同时提出质量管理环节中建立伦理委员会的内部评估机制,并定期进行独立于伦理委员会的第三方评估的重要意义。 | Fergus Sweeney | 2011 | 医学与哲学(A)2011，32，5： | 6 |
| 4 | Refining pathological evaluation of neoadjuvant therapy for adenocarcinoma of the esophagus显示文摘AIM:To assess tumour regression grade(TRG)and lymph node downstaging to help define patients who benefit from neoadjuvant chemotherapy.METHODS:Two hundred and eighteen consecutive patients with adenocarcinoma of the esophagus or gastro-esophageal junction treated with surgery alone or neoadjuvant chemotherapy and surgery between 2005and 2011 at a single institution were reviewed.Triplet neoadjuvant chemotherapy consisting of platinum,fluoropyrimidine and anthracycline was considered for operable patients(World Health Organization performance status≤2)with clinical stage T2-4 N0-1.Response to neoadjuvant chemotherapy(NAC)was assessed using TRG,as described by Mandard et al.In addition lymph node downstaging was also assessed.Lymph node downstaging was defined by cN1 at diagnosis:assessed radiologically(computed tomography,positron emission tomography,endoscopic ultrasonography),then pathologically recorded as N0 after surgery;ypN0 if NAC given prior to surgery,or pN0if surgery alone.Patients were followed up for 5 years post surgery.Recurrence was defined radiologically,with or without pathological confirmation.An association was examined between t TRG and lymph node downstaging with disease free survival(DFS)and a comprehensive range of clinicopathological characteristics.RESULTS:Two hundred and eighteen patients underwent esophageal resection during the study interval with a mean follow up of 3 years(median follow up:2.552,95%CI:2.022-3.081).There was a 1.8%(n=4)inpatient mortality rate.One hundred and thirty-six(62.4%)patients received NAC,with 74.3%(n=101)of patients demonstrating some signs of pathological tumour regression(TRG 1-4)and 5.9%(n=8)having a complete pathological response.Forty four point one percent(n=60)had downstaging of their nodal disease(cN1 to ypN0),compared to only 15.9%(n=13)that underwent surgery alone(pre-operatively overstaged:cN1 to pN0),(P<0.0001).Response to NAC was associated with significantly increased DFS(mean DFS;TRG 1-2:5.1years,95%CI:4.6-5.6 vs TRG 3-5:2.8 years,95%CI:2.2-3.3,P<0.0001).Nodal down-staging conferred a significant DFS advantage for those patients with a poor primary tumour response to NAC(median DFS;TRG 3-5 and nodal down-staging:5.533 years,95%CI:3.558-7.531 vs TRG 3-5 and no nodal down-staging:1.114 years,95%CI:0.961-1.267,P<0.0001).CONCLUSION:Response to NAC in the primary tumour and in the lymph nodes are both independently associated with improved DFS. | Fergus Noble Luke Nolan Adrian C Bateman James P Byrne Jamie J Kelly Ian S Bailey Donna M Sharland Charlotte N Rees Timothy J Iveson Tim J Underwood Andrew R Bateman | 2013 | World Journal of Gastroenterology2013，19，48： | 4 |
| 5 | Hypothalamic-Pituitary-Gut Axis Dysregulation in Irritable Bowel Syndrome: Plasma Cytokines as a Potential Biomarker?显示文摘 | Timothy G. Dinan Eamonn M.M. Quigley Salah M.M. Ahmed Paul Scully Sinead O’Brien Liam O’Mahony Siobhan O’Mahony Fergus Shanahan P.W. Napoleon Keeling | 2006 | Gastroenterology2006，，2： | 3 |
| 6 | Manipulation of the Microbiota for Treatment of IBS and IBD—Challenges and Controversies显示文摘 | Fergus Shanahan Eamonn M.M. Quigley | 2014 | Gastroenterology2014，，： | 3 |
| 7 | A Molecular Analysis of Fecal and Mucosal Bacterial Communities in Irritable Bowel Syndrome显示文摘 | Caroline Codling Liam O’Mahony Fergus Shanahan Eamonn M. M. Quigley Julian R. Marchesi | 2010 | Digestive Diseases and Sciences2010，，2： | 3 |
| 8 | Diagnostic accuracy and clinical application of faecal calprotectin in adult patients presenting with gastrointestinal symptoms in primary care显示文摘 | Polychronis Pavlidis Fergus JQ Chedgy Jeremy A Tibble | 2013 | Scandinavian Journal of Gastroenterology2013，，9： | 2 |
| 9 | Acetic acid chromoendoscopy: Improving neoplasia detection in Barrett's esophagus显示文摘Barrett's esophagus(BE) is an important condition given its significant premalignant potential and dismal five-year survival outcomes of advanced esophageal adenocarcinoma. It is therefore suggested that patients with a diagnosis of BE undergo regular surveillance in order to pick up dysplasia at an earlier stage to improve survival. Current 'gold-standard' surveillance protocols suggest targeted biopsy of visible lesions followed by four quadrant random biopsies every 2 cm. However, this method of Barrett's surveillance is fraught with poor endoscopist compliance as the procedures are time consuming and poorly tolerated by patients. There are also significant miss-rates with this technique for the detection of neoplasia as only 13% of early neoplastic lesions appear as visible nodules. Despite improvements in endoscope resolution these problems persist. Chromoendoscopy is an extremely useful adjunct to enhance mucosal visualization and characterization of Barrett's mucosa. Acetic acid chromoendoscopy(AAC) is a simple, non-proprietary technique that can significantly improve neoplasia detection rates. This topic highlight summarizes the current evidence base behind AAC for the detection of neoplasia in BE and provides an insight into the direction of travel for further research in this area. | Fergus JQ Chedgy Sharmila Subramaniam Kesavan Kandiah Sreedhari Thayalasekaran Pradeep Bhandari | 2016 | World Journal of Gastroenterology2016，22，25： | 2 |
| 10 | Lactobacillus and bifidobacterium in irritable bowel syndrome: Symptom responses and relationship to cytokine profiles显示文摘 | Liam O’Mahony Jane McCarthy Peter Kelly George Hurley Fangyi Luo Kersang Chen Gerald C. O’Sullivan Barry Kiely J. Kevin Collins Fergus Shanahan Eamonn M.M. Quigley | 2005 | Gastroenterology2005，，3： | 2 |
| 11 | Enterococcus faecalis Metalloprotease Compromises Epithelial Barrier and Contributes to Intestinal Inflammation显示文摘 | Natalie Steck Micha Hoffmann Irina G. Sava Sandra C. Kim Hannes Hahne Susan L. Tonkonogy Katrin Mair Dagmar Krueger Mihaela Pruteanu Fergus Shanahan Roger Vogelmann Michael Schemann Bernhard Kuster R. Balfor Sartor Dirk Haller | 2011 | Gastroenterology2011，，3： | 2 |
| 12 | Selenium and Iodine Deficiencies and Selenoprotein Function显示文摘This paper reviews some recent findings on the interactions between selenium deficiency and iodine deficency. Both micronutrients can control the levels of selenoprotein mRNAs, particularly in the thyroid and brain. When selenium and iodine supplies are limiting the compensatory mechanisms work to minimise adverse effects on thyroid hormone metabolsm and thus neurological developtnent. The mechanisms for regulation of selenoproteins in selenium and iodine deficiency are however very tissue-specific. For example, unlike the brain and thyroid,brown adipose tissue is unable to retain selenoproteins in selenium and iodine deficiency and is therefore at greater risk from injurious effects of the deficiencies. | JOHN R. ARTHUR FERGUS NICOL JULIE H. MITCHELL AND GEOFFREY J. BECKETT(Division Of Biochemical Sciences, Rowett Research Institute, Bucksburn, Aberdeen AB21 9SB, UK Cellular Endocrinology Unit,University Department of Clinical Biochemistry, The Royal In | 1997 | Biomedical and Environmental Sciences1997，10，2： | 2 |
| 13 | Radiologic Imaging in Cystic Fibrosis显示文摘 | Oisin J. O’Connell Sebastian McWilliams AnneMarie McGarrigle Owen J. O’Connor Fergus Shanahan David Mullane Joseph Eustace Michael M. Maher Barry J. Plant | 2012 | Chest2012，，： | 2 |
| 14 | A semi-automated in vitro gas production technique for ruminant feedstuff evaluation显示文摘 | Rogerio M Mauricio Fergus L Mould Mewa S Dhanoa Emyr Owen Kulwant S Channa Michael K Theodorou | 1999 | Animal Feed Science and Technology1999，，4： | 2 |
| 15 | Recent developments in cathode materials for lithium ion batteries显示文摘 | Jeffrey W. Fergus | 2009 | Journal of Power Sources2009，，4： | 2 |
| 16 | Computed tomography findings mimicking appendicitis as a manifestation of colorectal cancer显示文摘 | Richard E. Watchorn Liina Poder Zhen J. Wang Benjamin M. Yeh Emily M. Webb Fergus V. Coakley | 2009 | Clinical Imaging2009，，6： | 2 |
| 17 | Learning generative visual models from few training examples: An incremental Bayesian approach tested on 101 object categories显示文摘 | Li Fei-Fei Rob Fergus Pietro Perona | 2006 | Computer Vision and Image Understanding2006，，1： | 2 |
| 18 | A prospective feasibility study of sub-millisievert abdominopelvic CT using iterative reconstruction in Crohn’s disease显示文摘 | Siobhan B O’Neill Patrick D Mc Laughlin Lee Crush Owen J O’Connor Sebastian R Mc Williams Orla Craig Anne Marie Mc Garrigle Fiona O’Neill Jackie Bye Max F. Ryan Fergus Shanahan Michael M Maher | 2013 | European Radiology2013，，： | 2 |
| 19 | Lanthanum Chromite-based Materials for Solid Oxide Fuel Cell Interconnects显示文摘 | Fergus J W | 2004 | Solid State lonics2004，171，： | 1 |
| 20 | Spectral Hashing显示文摘 | Weiss Y Torralba A Fergus R | 2008 | Advances in Neural Information Processing Systems2008，21，： | 1 |
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