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| 1 | Bone Regeneration Based on Tissue Engineering Conceptions – A 21st Century Perspective显示文摘The role of Bone Tissue Engineering in the field of Regenerative Medicine has been the topic of substantial research over the past two decades.Technological advances have improved orthopaedic implants and surgical techniques for bone reconstruction.However,improvements in surgical techniques to reconstruct bone have been limited by the paucity of autologous materials available and donor site morbidity.Recent advances in the development of biomaterials have provided attractive alternatives to bone grafting expanding the surgical options for restoring the form and function of injured bone.Specifically,novel bioactive(second generation)biomaterials have been developed that are characterised by controlled action and reaction to the host tissue environment,whilst exhibiting controlled chemical breakdown and resorption with an ultimate replacement by regenerating tissue.Future generations of biomaterials(third generation)are designed to be not only osteoconductive but also osteoinductive,i.e.to stimulate regeneration of host tissues by combining tissue engineering and in situ tissue regeneration methods with a focus on novel applications.These techniques will lead to novel possibilities for tissue regeneration and repair.At present,tissue engineered constructs that may find future use as bone grafts for complex skeletal defects,whether from post-traumatic,degenerative,neoplastic or congenital/developmental'origin'require osseous reconstruction to ensure structural and functional integrity.Engineering functional bone using combinations of cells,scaffolds and bioactive factors is a promising strategy and a particular feature for future development in the area of hybrid materials which are able to exhibit suitable biomimetic and mechanical properties.This review will discuss the state of the art in this field and what we can expect from future generations of bone regeneration concepts. | Jan Henkel Maria A.Woodruff Devakara R.Epari Roland Steck Vaida Glatt Ian C.Dickinson Peter F.M.Choong Michael A.Schuetz Dietmar W.Hutmacher | 2013 | Bone Research2013，1，3： | 33 |
| 2 | Enterococcus faecalis Metalloprotease Compromises Epithelial Barrier and Contributes to Intestinal Inflammation显示文摘 | Natalie Steck Micha Hoffmann Irina G. Sava Sandra C. Kim Hannes Hahne Susan L. Tonkonogy Katrin Mair Dagmar Krueger Mihaela Pruteanu Fergus Shanahan Roger Vogelmann Michael Schemann Bernhard Kuster R. Balfor Sartor Dirk Haller | 2011 | Gastroenterology2011，，3： | 2 |
| 3 | PAH-DNA adducts, cigarette smoking, GST polymorphisms, and breast cancer risk显示文摘 | McCarty K M Santella R M Steck S E | 2009 | Environ Health Perspect2009，117，4： | 1 |
| 4 | Lycopene and cardiovascular disease 显示文摘 | Arab L Steck S | 2000 | Am J Clin Nutr2000，71，6： | 1 |
| 5 | Electrophoretic analysis of the major polypeptides of the human erythrocyte membrane显示文摘 | Fairbanks G Steck TL Wallach DFH | 1971 | Biochemistry1971，10，： | 1 |
| 6 | Production and Transportation Integration for a Make-to-Order Manufacturing Company with a Commit-to-Delivery Busilless Mode 显示文摘 | Kathryn E Stecke Xuying Zhao | 2007 | Manufacturing & Service Operations Management2007，9，2： | 1 |
| 7 | Lycopene and cardiovascular disease显示文摘 | Lenore Arab Susan Steck | 2000 | American Society for Clinical Nutrition2000，71，6： | 1 |
| 8 | Zone of traction injury of the common peroneal nerve显示文摘 | Prasad AR Steck JK Dellon AL | 2007 | Ann Plast Surg2007，59，3： | 1 |
| 9 | A new dietary inflammatory index predicts interval changes in serum high-sensitivity C-reactive protein显示文摘 | Cavicchia P P Steck S E Hurley T G Hussey J R Ma Y Ockene I S | 2009 | J Nutr2009，139，： | 1 |
| 10 | Induction of intervertebral disc-like cel s from adult mesenchymal stem cel s显示文摘 | Steck E Bertram H Abel R | | 0，，03： | 1 |
| 11 | Ammonium-based alkaline- free synthesis of MFI-type boron and titanium zeolites 显示文摘 | MuLLER U STECK W | 1994 | Stud Surf Sci Catal1994，84，： | 1 |
| 12 | Zone of traction injury of the common peroneal nerve显示文摘 | Prasad A R Steck J K Dellon A L | 2007 | Ann Plast Surg2007，59，： | 1 |
| 13 | Design, planning, scheduling, and control problems of flexible manufacturing systems显示文摘 | STECKE K E | 1985 | Annals of Operations Research1985，3，1： | 1 |
| 14 | A straightforward introduction to continuous quantum measurement显示文摘 | Jacobs K Steck D A | 2006 | Comtemporary Physics2006，47，5： | 1 |
| 15 | Isolation and structure elucidation of earotenoid-glycosyl esters in Gardenia Fruits (Gardenia jasminoides Ellis) and Saffron (Crocus sativus Linne) 显示文摘 | PFISTER S MEYER P STECK A | 1996 | J Agric Food Chem1996，44，9： | 1 |
| 16 | Clinical features and pathophys-iologieal basis of sensory neuronopathies(gansionopathies)显示文摘 | Antoine JC Steck AJ | 2004 | Muscle Nerve2004，30，3： | 1 |
| 17 | Support Vector Machines for Classifying and Describing Credit Applicants: Detecting Typical and Critical Re- gions 显示文摘 | Schebesch K B Stecking R | 2005 | Journal of the Operational Research Society2005，，56： | 1 |
| 18 | Racial disparities in colorectal cancer incidence by type 2 diabetes mellitus status显示文摘 | Cavicchia PP Adams SA Steck SE | 2013 | Cancer causes and control2013，24，2： | 1 |
| 19 | Biomimetic tubular nanofiber mesh and platelet rich plasma-mediated delivery of BMP-7 for large bone defect regeneration显示文摘 | A. Berner J. Boerckel S. Saifzadeh R. Steck J. Ren C. Vaquette J. Zhang M. Nerlich R. Guldberg D. Hutmacher M. Woodruff | 2012 | Cell and Tissue Research2012，，3： | 1 |
| 20 | The metaphyseal bone defect in distal radius fractures and its implication on trabecular remodeling-a histomorphometric study (case series)显示文摘 | Lutz M Steck R Sitte I | 2015 | J Orthop Surg Res2015，10，1： | 1 |
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