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| 1 | High-throughput screening of mouse gene knockouts identifies established and novel skeletal phenotypes显示文摘Screening gene function in vivo is a powerful approach to discover novel drug targets. We present high-throughput screening(HTS) data for 3 762 distinct global gene knockout(KO) mouse lines with viable adult homozygous mice generated using either gene-trap or homologous recombination technologies. Bone mass was determined from DEXA scans of male and female mice at 14 weeks of age and by microCT analyses of bones from male mice at 16 weeks of age. Wild-type(WT) cagemates/littermates were examined for each gene KO. Lethality was observed in an additional 850 KO lines. Since primary HTS are susceptible to false positive findings, additional cohorts of mice from KO lines with intriguing HTS bone data were examined. Aging,ovariectomy, histomorphometry and bone strength studies were performed and possible non-skeletal phenotypes were explored. Together, these screens identified multiple genes affecting bone mass: 23 previously reported genes(Calcr, Cebpb, Crtap, Dcstamp, Dkk1, Duoxa2, Enpp1, Fgf23, Kiss1/Kiss1 r, Kl(Klotho),Lrp5, Mstn, Neo1, Npr2, Ostm1, Postn, Sfrp4, Slc30a5, Slc39a13, Sost, Sumf1, Src, Wnt10b), five novel genes extensively characterized(Cldn18, Fam20 c, Lrrk1, Sgpl1, Wnt16), five novel genes with preliminary characterization(Agpat2, Rassf5, Slc10a7, Slc26a7, Slc30a10) and three novel undisclosed genes coding for potential osteoporosis drug targets. | Robert Brommage Jeff Liu Gwenn M Hansen Laura L Kirkpatrick David G Potter Arthur T Ss Brian Zambrowicz David R Powell Peter Vogel | 2014 | Bone Research2014，2，3： | 7 |
| 2 | 多作者署名与研究分析显示文摘Web of Science中不断涌现出拥有1000个、甚至更多作者,横跨100多个国家的研究论文。众多作者/众多国家的组合产生出复杂的作者署名模式,它不同于传统的典型学术论文,而且推升了论文引用率。在该报告中,我们将描述两种模式,它们将复杂作者署名与引用率提升效应关联在一起:与多作者署名(超过10个作者,5个以上国家)相关的普遍性引用率提升;超大规模作者署名(超过100个作者,超过30个国家)导致的更具扰动性的结果. | Jonathan Adams David Pendlebury Ross Potter Martin Szomszor | 2020 | 科学观察2020，15，4： | 4 |
| 3 | 病害防治措施显示文摘美国北卡罗莱纳州立大学农业推广服务部(Agricuetural Extension Service north Caroeina University),每年对该州烟草生产,均发布《烟草资料》(“Tobacco Information”),这一刊物是用以指导烟草生产的技术指南。兹将《1989年烟草资料》(“Tobacco Informetion1989”)中第62~94页的烤烟“病害防治措施”的大部分,摘译出来,供我国从事烤烟病害防治和烟草病害调查的同志们参考。 | Jhomar A. meeton David Potter Keith Wood 陈瑞泰 | 1989 | 中国烟草科学1989，，2： | 2 |
| 4 | Proximal Humerus Reconstructions for Tumors显示文摘 | Benjamin K. Potter MD Sheila C. Adams MD J. David Pitcher MD Theodore I. Malinin MD H. Thomas Temple MD | 2009 | Clinical Orthopaedics and Related Research2009，，4： | 2 |
| 5 | Rallying the troops: innate mucosal responses to enteric pathogens显示文摘 | David JAsper Justin Gawaziuk Andrew A Potter | 2009 | Cur- rent Immunology Reviews2009，5，4： | 1 |
| 6 | Enrichment improves cognition in AD mice by amyloid-related and unrelated mechanisms显示文摘 | David A. Costa Jennifer R. Cracchiolo Adam D. Bachstetter Tiffany F. Hughes Kelly R. Bales Steven M. Paul Ronald F. Mervis Gary W. Arendash Huntington Potter | 2006 | Neurobiology of Aging2006，，： | 1 |
| 7 | Calpain regulates actin remodeling during cell spreading显示文摘 | DAVID A POTTER JENNFER S TIRNAUER RICHARD JANSSEN | 1998 | Cell Biology1998，141，： | 1 |
| 8 | A Dynamic Model,Including Contact Bounce,of an Electrostatically Actuated Microswitch显示文摘 | McCarthy Brian Adams George G McGruer Nicol E Potter David | 2002 | Journal of Microelectromechanical Systems2002，11，3： | 1 |
| 9 | Decision-making using fMRI in clinical drug development: revisiting NK-1 receptor antagonists for pain显示文摘 | David Borsook Jaymin Upadhyay Michael Klimas Adam J. Schwarz Alexandre Coimbra Richard Baumgartner Edward George William Z. Potter Thomas Large David Bleakman Jeffrey Evelhoch Smriti Iyengar Lino Becerra Richard J. Hargreaves | 2012 | Drug Discovery Today (-)2012，，17： | 1 |
| 10 | Diffusion tensor imaging of cerebral white matter integrity in cognitive aging显示文摘 | David J. Madden Ilana J. Bennett Agnieszka Burzynska Guy G. Potter Nan-kuei Chen Allen W. Song | 2011 | BBA - Molecular Basis of Disease2011，，3： | 1 |
| 11 | Increasing the value of weather-related warnings显示文摘Despite advances in forecasting and emergency preparedness, weather related disasters continue to cost many lives, to displace populations and to cause wide-spread damage. Therefore, High Impact Weather Project (HIWeather), a 10-year research project (http://gffzz72c37a797ca44d97s9kb06bq0cuf06kob.ffgz.tsg.suse.edu.cn/en/resources/buHetin/hiweather-10-yearresearch- project), was established in 2016 by WM0 (World Meteorology Organization) WWRP (World Weather Research Program: http://gffzz74e393fd09b145d8s9kb06bq0cuf06kob.ffgz.tsg.suse.edu.cn/pages/prog/arep/wwrp/new/wwrp_new_en. html). HIWeather aimed at achieving dramatic improvements in the effectiveness of weather-related hazard warnings, following recent advancement in numerical weather prediction at km-scale and in disaster risk reduction. The implementation plan was developed under the concept of warning chain, which comprises all components and the connections between to a successful weather-hazards warning: observations, weather forecast, hazard forecast, impact forecast, the generation of warnings and decision making (Fig. 1). A successful warning relies on information produced by the meteorological and related physical sciences, thus its effectiveness of delivery depends on applications of social, behavioral and economic sciences. The workshop of WM0 High Impact Weather Project was held in Beijing during 20-22 November of 2018, attracted a diverse and interdisciplinary group of over 70 scientists from 25 countries in the broad field of physical and social science, during which all elements of the warning chain were discussed critically. | Qinghong Zhang Liye Li Beth Ebert Brian Golding David Johnston Brian Mills Shannon Panchuk Sally Potter Michael Riemer Juanzhen Sun Andrea Taylor Sarah Jones Paolo Ruti Julia Keller | 2019 | Science Bulletin2019，64，10： | 1 |
| 12 | Minimal Atrophy of the Entorhinal Cortex and Hippocampus: Progression of Cognitive Impairment显示文摘 | Varon Daniel Loewenstein David A Potter Elizabeth Greig Maria T Agron Joscelyn Shen Qian Zhao Weizhao Celeste Ramirez Maria Santos Isael Barker Warren Potter Huntington Duara Ranjan | 2011 | EN2011，，4： | 1 |
| 13 | Accumulation of α-synuclein in the bowel of patients in the pre-clinical phase of Parkinson’s disease显示文摘 | David Hilton Madeleine Stephens Leanne Kirk Philip Edwards Ross Potter John Zajicek Ellie Broughton Hannah Hagan Camille Carroll | 2014 | Acta Neuropathologica2014，，2： | 1 |
| 14 | Identification of Catalytic Residues in Human Mevalonate Kinase显示文摘 | David Potter Hellry M Miziorko | 1997 | The journal of biological chemistry1997，，25： | 1 |
| 15 | American Society for Therapeutic Radiology and Oncology (ASTRO) and American College of Radiology (ACR) Practice Guideline for the Performance of Stereotactic Body Radiation Therapy显示文摘 | Louis Potters Brian Kavanagh James M. Galvin James M. Hevezi Nora A. Janjan David A. Larson Minesh P. Mehta Samuel Ryu Michael Steinberg Robert Timmerman James S. Welsh Seth A. Rosenthal | 2010 | International Journal of Radiation Oncology, Biology, Physics2010，，2： | 1 |
| 16 | The epidemiology of autistic spectrum disorders:Is the prevalence rising显示文摘 | LORNA WING DAVID POTTER | | 0，，08： | 1 |
| 17 | Habitat connectivity, more than species’ biology, influences genetic differentiation in a habitat specialist, the short-eared rock-wallaby (Petrogale brachyotis)显示文摘 | Sally Potter Mark Eldridge Steven Cooper Justyna Paplinska David Taggart | 2012 | Conservation Genetics2012，，4： | 1 |
| 18 | Modelling of the spring-in phenomenon in curved parts made of a thermosetting composite显示文摘 | Nuri Ersoy Tomasz Garstka Kevin Potter Michael R. Wisnom David Porter Graeme Stringer | 2009 | Composites Part A2009，，3： | 1 |
| 19 | [仪表]用新型仪表了解环境变化显示文摘全球气候变暖的现象已经非常严重,探索相对应的解决方案需要全世界的工程师和科学家们共同努力合作。而探索出来的最终结果需要依靠原来一直没有公布的、由成千上万分布在世界各地的检测仪器提供的大量可靠数据来进行分析。政府间气候变化专业委员会(IPCC)在其20047年度的情况报告中报道说:全球性的气候变暖速度已经明显加快,全球的气温和水温上的升趋势非常明显。 | David Potter Caroline Bright | 2010 | 现代制造2010，，1： | 0 |
| 20 | Sustainable Water Resources Management: River Basin Modelling and Decision Support Framework显示文摘Sustainability is a key objective of water resources management and this paper describes a modelling and decision support framework that achieves this, illustrated by applications on the UK Thames and Mekong river basins. The decision support framework contains several modules, including an interactive user's interface linked to a GIS, a geo-database, knowledge base, simulation models and optimization procedures. Based on the analysis of scenarios and proposed interventions, efficient modelling and optimization tools form a comprehensive integrated decision support framework for the analysis and operational management of water resources in the river basin, our emphasis has been on a practical implementation through careful screening of alternatives, consideration of the institutional framework and direct involvement of stakeholders in the decision making process. Operating in this environment is transparent, reproducible and auditable, securing the trust of all interested parties. This paper discusses its applications to water utilisation on the Mekong river basin and drought management of the Lower Thames stored reservoir system. | RAO Zhengfu POTTER Bob WEBB David PARKIN Ralph | 2009 | Wuhan University Journal of Natural Sciences2009，14，6： | 0 |
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