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| 1 | 血管性认知损害诊断的进一步规范化:血管性认知损害分类共识研究组指南显示文摘引言血管性认知损害(vascular cognitive impairment,VCI)诊断共识的缺乏(体现为多种不同评估方案的使用),妨碍了对其理解和治疗的推进.多个国家的大量临床医生和研究人员参与了2个阶段血管性认知损害分类共识研究(Vascular Impairment of Cognition Classification Consensus Study,VICCCS),旨在就VCI的诊断原则(VICCCS-1)和诊断方案(VICCCS-2)达成一致意见.本文提供了VICCCS-2的相关内容.方法使用VICCCS-1达成的原则和已发表的诊断指南作为在线德尔菲(Delphi)调查的参考基点,以期对VCI的临床诊断达成共识.结果共进行了6轮调查,每轮有65~79名专家参与,他们就VICCCS修订的轻度和重度VCI的诊断指南达成共识,并肯定了美国国立神经疾病与卒中研究所-加拿大卒中网(National Institute of Neurological Disorders and Stroke–Canadian Stroke Network,NINDS-CSN)发布的神经心理学评估方案和对影像学检查的推荐意见.讨论VICCCS-2建议规范化应用NINDS-CSN推荐的神经心理学和影像学评估方案诊断VCI,以促进研究协作. | Olivia A. Skrobot Sandra E. Black Christopher Chen Charles DeCarli Timo Erkinjuntti Gary A. Ford Rajesh N. Kalaria John O'Brien Leonardo Pantoni Florence Pasquier Gustavo C. Roman Anders Wallin Perminder Sachdev Ingmar Skoog the VICCCS group Yoav Ben-Shlomo Anthony P. Passmore Seth Love Patrick G. Kehoe 朱婷珂 徐俊 | 2018 | 国际脑血管病杂志2018，26，4： | 58 |
| 2 | Corrosion Protection Properties of Organofunctional Silanes ——An Overview显示文摘The aim of this paper is to review the development and state of the art in the application of cer- tain organosilicon compounds known as trialkoxysilanes (or simply silanes) to the problems of the metal finishing industry. The ultimate goal of this work is the replacement of chromate passivation and paint pretreatments, as well as overcoming the shortcomings of organic coatings formulated in the modern environmentally friendly world, thus without chromate or chromated pigments, volatile organic carbon (VOC) containing compounds or harazardous air pollutants (HAPs). | W. J. van Ooij D. Zhu M. Stacy A. Seth T. Mugada J. Gandhi P. Puomi | 2005 | Tsinghua Science and Technology2005，10，6： | 47 |
| 3 | Antiviral innate immunity pathways显示文摘最近的研究揭开了激活主人的二个发信号小径对病毒的感染的天生的免疫。小径之一利用像使用费的受体(TLR ) 的成员检测通过 endocytosis 进入内涵体的病毒的家庭。TLR 小径通过最终导致抄写因素 NF-kappaB, IRF3 和 IRF7 的激活的几发信号的蛋白质导致干扰素生产。另外的抗病毒的小径为细胞内部的病毒的双 stranded RNA 把 RNA helicase RIG-I 用作受体。RIG-I 通过最近识别的适配器蛋白质 MAVS 激活 NF-kappaB 和 IRF,包含居住在 mitochondrial 膜的蛋白质的一个卡片领域。MAVS 为抗病毒的天生的免疫是必要的,但是它也用作丙肝病毒(HCV ) 的一个目标,它采用病毒的朊酶劈开 MAVS 离开线粒体,从而允许 HCV 逃离主人免疫系统。 | Rashu B Seth Lijun Sun Zhijian J Chen | 2006 | Cell Research2006，16，2： | 45 |
| 4 | 西藏班公湖-怒江缝合带——深部地球物理结构给出的启示显示文摘通过跨越缝合带的综合地球物理和地质调查研究,查明了地质上推测的“班公湖-怒江缝合带”的深部结构和构造,提出了下述观点现有资料尚不足以证明,“班公湖-怒江缝合带”是严格意义上的缝合带,而趋向表明是一个老的弧后拉张区,在后来的印度大陆与拉萨地块碰撞挤压过程中,先是沉积了巨厚的第三纪地层,仅在20Ma(?)以来才转变成挤压体制,形成多条逆冲断裂;纳木错-申扎逆冲的蛇绿岩片带代表着侏罗纪洋的主要缝合带位置,在其闭合过程中洋壳与陆壳一起向北发生俯冲,并形成班戈岩带所代表的岩浆弧,在岩浆弧后出现了拉张区;下地壳向北挤压增厚,物理性质不同的上、下地壳之间相互运动而形成了一条缓倾的剪切片理化带,南北长达300km,命名为主羌塘逆冲断裂带(MQT);并使班戈岩片整体向南逆推上去,致使地壳分层增厚;在拉张期伦坡拉小地块向下运动,20Ma以后转变成压缩体制后又开始向上逆推,再加上后期的剥蚀,致使班戈深成岩体出露于地表;唐古拉山、各拉丹冬等年轻的火山岩浆带与地表显示的构造活动无直接关系,推测应是地壳深层作用引起的构造岩浆活动的显示。 | 赵文津 刘葵 蒋忠惕 吴珍汉 赵逊 史大年 熊嘉育 J.Mechie L.Brown T.Hearn J.R.Guo Seth S.Haines | 2004 | 地质通报2004，23，7： | 37 |
| 5 | 特拉华欺负受害量表(学生卷)中文版信、效度研究显示文摘目的:检验特拉华欺负受害量表(学生卷)(DBVS-S)中文版在中国青少年中的信度和效度。方法:应用中文版DBVS-S对湖南省4个地区10所学校小学六年级至高三2443名学生施测,以流调中心抑郁量表(CES-D)、学生生活满意度量表(SLSS)和Olweus儿童欺负问卷(BVQ)为效标,测评效标关联效度,随机抽取其中2个班计117名被试间隔4周后重测。结果:1DBVS-S中文版维度结构与原量表一致,探索性因素分析和验证性因素分析均支持三因子结构模型;2DVBS-S中文版总分与CES-D和BVQ的相关系数分别为0.360和0.766(P<0.001),与SLSS的相关系数为-0.184(P<0.001);3总量表α系数为0.839,4周后的重测相关系数为0.684。结论:特拉华欺负受害量表(学生卷)中文版具有较好的信效度。 | 谢家树 吕永晓 George G.Bear Chunyan Yang Seth J.Marshall Rong Gong | 2015 | 中国临床心理学杂志2015，23，4： | 21 |
| 6 | 特拉华校园氛围量表(学生卷)中文版信、效度研究显示文摘目的:检验特拉华校园氛围量表(学生卷)(DSCS-S)中文版在中国青少年中的信度和效度。方法:应用中文版特拉华校园氛围量表对2552名中小学生施测,四周后抽取其中125名被试重测;以流调中心抑郁量表(CESD)、学生生活满意度量表(SLSS)和特拉华欺负受害量表(学生卷)(DBVS-S)为效标,检验其校标关联效度。结果:1探索性因素分析和验证性因素分析均支持量表的八因素结构模型;28因子模型各主要拟合指标为RESEA=0.050;CFI=0.901;χ2/df=5.110;GFI=0.923;IFI=0.910;DSCS-S与CES-D相关系数为-0.76(P<0.01),与SLSS相关系数为0.33(P<0.01);与DBVS-S的相关系数为-0.20(P<0.01);3总量表α系数为0.80,重测信度为0.68。结论:特拉华校园氛围量表(学生卷)(DSCS-S)中文版具有良好的信效度。 | 谢家树 吕永晓 马坤 谢璐 George G.Bear Chunyan Yang Seth J.Marshall Rong Gong | 2016 | 中国临床心理学杂志2016，24，2： | 21 |
| 7 | 大陆内部长余震序列及其对地震风险评估的启示显示文摘板块构造学说的最有力的特征之一,是已知的板块运动让我们对板块边界未来大地震的发震位置和平均复发间隔有更清晰的认识。然而,板块构造学说却不能预测板块内的地震何时何地发生,因为理想的板块内部是不会变形的。因此,板块内部的地震风险评估过于依靠如下假设:从有限的历史记录中得到的小地震发震位置能够反映出连续变形的地区,而变形将诱发未来大地震[1]。然而,本文将要说明的是,最近许多这样的小地震很可能是几百年前发生过的大地震的余震。文中将给出一个简单的模型,并由此模型得出:余震序列的长度和断层加载速率呈反比关系。发生在缓慢变形的大陆内部的余震序列,其持续时间与在快速加载的板块边界所观测到的典型的10年尺度余震序列相比要长得多。因为这些预测与观测结果相符,所以将大陆内部地震看作稳态地震活动的一般做法高估了目前地震活跃地区的地震危险性,而低估了其他地区的地震风险。 | Seth Stein Mian Liu 刘杨(译) 朱守彪(校) | 2009 | 国际地震动态2009，，12： | 19 |
| 8 | Burden of Gastrointestinal Disease in the United States: 2012 Update显示文摘 | Anne F. Peery Evan S. Dellon Jennifer Lund Seth D. Crockett Christopher E. McGowan William J. Bulsiewicz Lisa M. Gangarosa Michelle T. Thiny Karyn Stizenberg Douglas R. Morgan Yehuda Ringel Hannah P. Kim Marco Dacosta DiBonaventura Charlotte F. Carroll Je | 2012 | Gastroenterology2012，，5： | 15 |
| 9 | 沥青质分散剂评价方法改进与新型高效分散剂合成显示文摘为了更加高效准确地评价沥青质分散剂,首次利用测定掺稀后黏度变化的实验方法取代现有沉淀评价方法,结合对现有市售分散剂的评价结果,分析了原有方法的缺点与不足。利用新方法探索了不同基团、链长、结构对分散剂分散性能的影响。结果表明,在用沉淀法测定时,强极性的烷基苯磺酸和长链离子液体分散剂出现增稠现象。针对塔河某掺稀井最为合适的沥青质分散剂应是具有C18烷基链长、含有2~4个极性头基团的多胺类非离子型表面活性剂。在此基础上,以油酸和二乙烯三胺合成了新型的长链烷基酰胺二胺型沥青质分散剂。通过掺稀黏度法测得,新合成的分散剂与沥青混合液在30、60℃下的平均黏度为890和277 m Pa·s,比常用的Span80多元醇类分散剂分别提高27%和46%。 | 周洪涛 贾寒 刘源 刘东亮 AJAY Seth 郑利强 | 2014 | 油田化学2014，31，4： | 15 |
| 10 | Foreign object ingestion and esophageal food impaction:An update and review on endoscopic management显示文摘Foreign body ingestion encompasses both foreign object ingestion(FOI) and esophageal food impaction(EFI) and represents a common and clinically significant scenario among patients of all ages. The immediate risk to the patient ranges from negligible to life-threatening, depending on the ingested substance,its location, patient fitness, and time to appropriate therapy. This article reviews the FOI and EFI literature and highlights important considerations and implications for pediatric and adult patients as well as their providers. Where published literature is insufficient to provide evidence-based guidance, expert opinion is included to supplement the content of this comprehensive review. | Brian M Fung Seth Sweetser Louis M Wong Kee Song James H Tabibian | 2019 | World Journal of Gastrointestinal Endoscopy2019，11，3： | 15 |
| 11 | Osteopontin increases hepatocellular carcinoma cell growth in a CD44 dependant manner显示文摘AIM:To investigate the role of osteopontin(OPN) and its splice variants in the proliferation of hepatocellular carcinoma(HCC).METHODS:The expression of OPN variants in HCC cell lines as well as HCC tissue samples and nontumour tissue was studied using polymerase chain reaction.OPN variant cDNAs were cloned into a mammalian expression vector allowing both transient expression and the production of stable OPN expressing cell lines.OPN expression was studied in these cells using Western blotting,immunofluoresnce and enzyme linked immunosorbent assay.A CD44 blocking antibody and siRNA targeting of CD44 were used to examine the role of this receptor in the OPN stimulated cell growth observed in culture.Huh-7 cells stably expressing either OPN-A,-B or-C were injected subcutaneously into the flanks of nude mice to observe in vivo tumour growth.Expression of OPN mRNA and protein in these tumours was examined using reverse transcriptionpolymerase chain reaction and immunohistochemistry.RESULTS:OPN is expressed in HCC in 3 forms,the full length OPN-A and 2 splice variants OPN-B and-C.OPN variant expression was noted in HCC tissue as well as cognate surrounding cirrhotic liver tissue.Expression of these OPN variants in the HCC derived cell line Huh-7 resulted in secretion of OPN into the culture medium.Transfer of OPN conditioned media to na ve Huh-7 and HepG2 cells resulted in significant cell growth suggesting that all OPN variants can modulate cell proliferation in a paracrine manner.Furthermore the OPN mediated increase in cellular proliferation was dependent on CD44 as only CD44 positive cell lines responded to OPN conditioned media while siRNA knockdown of CD44 blocked the proliferative effect.OPN expression also increased the proliferation of Huh-7 cells in a subcutaneous nude mouse tumour model,with Huh-7 cells expressing OPN-A showing the greatest proliferative effect.CONCLUSION:This study demonstrates that OPN plays a significant role in the proliferation of HCC through interaction with the cell surface receptor CD44.Modulation of this interaction could represent a novel strategy for the control of HCC. | Renee J Phillips Karla J Helbig Kylie H Van der Hoek Devanshi Seth Michael R Beard | 2012 | World Journal of Gastroenterology2012，18，26： | 12 |
| 12 | 纸的断裂韧性及其与纤维长度的关系显示文摘介绍了用断裂基功的概念测定纸张断裂韧性的新方法。并用此法研究了纤维长度对断裂韧性的影响,表明纸的断裂韧性与纤维长度几乎成直线关系;断裂韧性对纤维长度的依赖性比撕裂和抗张强度大。 | 彭毓秀 Seth,RS | 1994 | 中国造纸1994，13，4： | 10 |
| 13 | Screening and Surveillance for the Early Detection of Colorectal Cancer and Adenomatous Polyps, 2008: A Joint Guideline From the American Cancer Society, the US Multi-Society Task Force on Colorectal Cancer, and the American College of Radiology显示文摘 | Bernard Levin David A. Lieberman Beth McFarland Kimberly S. Andrews Durado Brooks John Bond Chiranjeev Dash Francis M. Giardiello Seth Glick David Johnson C. Daniel Johnson Theodore R. Levin Perry J. Pickhardt Douglas K. Rex Robert A. Smith Alan Thorson S | 2008 | Gastroenterology2008，，5： | 8 |
| 14 | Phytochrome-lnteracting Factors (PIFs) as Bridges between Environmental Signals and the Circadian Clock: Diurnal Regulation of Growth and Development显示文摘The rotation of the Earth around its axis results in distinct changes in light and temperature during a 24-h day/night cycle.Plants being sessile are constantly and predictably exposed to these environmental changes.It is therefore critical for them to properly perceive environmental signals in order to effectively manage growth and development. | Jieun Shin Muhammad Usman Anwer Seth Jon Davis | 2013 | Molecular Plant2013，6，3： | 8 |
| 15 | The Global Stratotype Section and Point (GSSP) for the base of the Katian Stage of the Upper Ordovician Series at Black Knob Ridge, Southeastern Oklahoma, USA显示文摘 | Daniel Goldman Stephen A. Leslie Jaak Nōlvak Seth Young Stig M. Bergstroem Warren D. Huff | 2007 | Episodes2007，30，4： | 7 |
| 16 | Peripheral primitive neuroectodermal tumor of the kidney presenting with pulmonary tumor embolism: A case report显示文摘Peripheral primitive neuroectodermal tumor(PNET) of the kidney is a rare, aggressive tumor known for its recurrence and metastatic potential. Despite the frequency of venous extension to the renal veins and inferior vena cava, pulmonary tumor embolism at the initial presentation is not common. We report a case of 22-year-old female with PNET of the kidney who presented with tumor embolism in the inferior vena cava(IVC) and bilateral pulmonary artery. The patient underwent surgical resection and histopathological analysis confirmed the presence of tumor within the IVC and pulmonary arteries. The patient received adjuvant chemotherapy and is currently doing well on follow-up. | Sathya Chinnaa Chandan J Das Sanjay Sharma Prabhjot Singh Amlesh Seth Suvendu Purkait Sandeep R Mathur | 2014 | World Journal of Radiology2014，6，10： | 7 |
| 17 | Can emergency physicians perform extended compression ultrasound for the diagnosis of lower extremity deep vein thrombosis?显示文摘BACKGROUND:Current point-of-care ultrasound protocols in the evaluation of lower extremity deep vein thrombosis (DVT) can miss isolated femoral vein clots.Extended compression ultrasound (ECUS) includes evaluation of the femoral vein from the femoral vein/deep femoral vein bifurcation to the adductor canal.Our objective is to determine if emergency physicians (EPs) can learn ECUS for lower extremity DVT evaluation after a focused training session.METHODS:Prospective study at an urban academic center.Participants with varied ultrasound experience received instruction in ECUS prior to evaluation.Two live models with varied levels of difficult sonographic anatomy were intentionally chosen for the evaluation.Each participant scanned both models.Pre-and post-study surveys were completed.RESULTS:A total of 96 ultrasound examinations were performed by 48 participants (11 attendings and 37 residents).Participants' assessment scores averaged 95.8% (95% CI 93.3%-98.3%) on the easier anatomy live model and averaged 92.3% (95% CI 88.4%-96.2%) on the difficult anatomy model.There were no statistically significant differences between attendings and residents.On the model with easier anatomy,all but 1 participant identified and compressed the proximal femoral vein successfully,and all participants identified and compressed the mid and distal femoral vein.With the difficult anatomy,97.9% (95% CI93.8%-102%) identified and compressed the proximal femoral vein,whereas 93.8% (95% CI 86.9%-100.6%) identified and compressed the mid femoral vein,and 91.7% (95% CI83.9%-99.5%) identified and compressed the distal femoral vein.CONCLUSION:EPs at our institution were able to perform ECUS with good reproducibility after a focused training session. | Elaine Situ-LaCasse Helpees Guirguis Lucas Friedman Asad E.Patanwala Seth E.Cohen Srikar Adhikari | 2019 | World Journal of Emergency Medicine2019，10，4： | 6 |
| 18 | Time for a Nuclear Meeting: Protein Trafficking and Chromatin Dynamics Intersect in the Plant Circadian System显示文摘生理节奏的钟调停改编到 24-h 世界。在 Arabidopsis,很生理节奏钟的部件在原子核充当 transcriptional 管理者并且产生抄本累积的有韵律的摆动。在这评论,我们集中于调制生理节奏钟的部件的活动的 post-transcriptional 事件,例如 phosphorylation, ubiquitination 和调停 proteasome 的降级,在细胞的本地化的变化,和 proteinprotein 相互作用。这些进程被发现了为生理节奏的功能,不是仅仅在植物,而且在另外的生理节奏的系统必要。而且,表明网络的光和钟高度被互连。在原子核,光和钟部件一起工作产生 transcriptional 节奏,导致预定的一般控制种生理的过程。 | Eva Herrero Seth J. Davis | 2012 | Molecular Plant2012，5，3： | 6 |
| 19 | 大陆内的长余震序列和对地震危险性评估的意义显示文摘板块构造学说最强大的特点之一,是通过已知的板块运动可以了解板块边界未来大地震的地点和平均复发间隔。然而板块构造学却不能探知板块之内何时何处发生地震,因为理想的板块内部不发生形变。因此,在板块内部,进行地震危险性评估主要依靠的假设是,短期历史记录给出的小地震的位置反映出连续形变从而引发未来大地震(Shed-locketal,2000)。然而在此我们提出,最近的这些地震有许多可能是数百年前大地震的余震。我们提出一简单模型可预测:余震序列的长度和断层应力加载的速率成反比。预测缓慢形变的大陆内的余震序列显著长于快速加载的板块边界通常观测到的10年。这些预测与观测结果一致。所以把大陆地震看作稳态地震活动的通行做法过高估计了现今活动地区的危险性,而低估了其他地区的地震危险性。 | Seth Stein 刘勉 杨雅琼(译) | 2009 | 世界地震译丛2009，40，4： | 6 |
| 20 | Clinical outcome of pediatric collagenous gastritis: Case series and review of literature显示文摘Collagenous gastritis (CG) is characterized by patchy subepithelial collagen bands. Effective treatment and the clinical and histological outcome of CG in children are poorly defined. The aim of this study is to summarize the published literature on the clinical outcome and response to therapy of pediatric CG including two new cases. We performed a search in Pubmed, OVID for related terms; articles including management and clinical and/or endo-histologic follow up information were included and abstracted. Reported findings were pooled in a dedicated database including the corresponding data extracted from chart review in our patients with CG. Twenty-four patients were included (17 females) with a mean age of 11.7 years. The clinical presentation included iron deficiency anemia and dyspepsia. The reported duration of follow up (in 18 patients) ranged between 0.2-14 years. Despite most subjects presenting with anemia including one requiring blood transfusion, oral iron therapy was only documented in 12 patients. Other treatment modalities were antisecretory measures in 13 patients; proton pump inhibitors (12), or histamine-2 blockers (3), sucralfate (5), prednisolone (6), oral budesonide in 3 patients where one received it in fish oil and triple therapy (3). Three (13%) patients showed no clinical improvement despite therapy; conversely 19 out of 22 were reported with improved symptoms including 8 with complete symptom resolution. Spontaneous clinical resolution without antisecretory, anti-inflammatory or gastroprotective agents was noted in 5 patients (4 received only supplemental iron). Follow up endohistopathologic data (17 patients) included persistent collagen band and stable Mononuclear cell infiltrate in 12 patients with histopathologic improvement in 5 patients. Neither collagen band thickness nor mononuclear cell infiltrate correlated with clinical course. Intestinal metaplasia and endocrine cell hyperplasia were reported (1) raising the concern of long term malignant transformation. In summary, CG in children is a chronic disease, typically with a variable clinical response and an indolent course that is distinct from the adult phenotype. Long term therapy usually inclused iron supplementation but cannot be standardized, given the chronicity of the disease, variability of response and potential for adverse events. | Nadia Mazen Hijaz Seth Steven Septer James Degaetano Thomas Mario Attard | 2013 | World Journal of Gastroenterology2013，19，9： | 5 |
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